The role of Agonistic Autoantibodies to the Angiotensin II Type 1 Receptor (AT1-AA) in Pathophysiology of Preeclampsia

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The role of Agonistic Autoantibodies to the Angiotensin II Type 1 Receptor (AT1-AA) in Pathophysiology of Preeclampsia is …
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scholarly articleQ13442814

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P356DOI10.2174/1389201019666180925121254
P932PMC publication ID6596412
P698PubMed publication ID30255752

P2093author name stringBabbette LaMarca
Mark W Cunningham
Nathan Campbell
P2860cites workPreeclampsia: long-term consequences for vascular healthQ26800272
Nitric oxide and reactive oxygen species in the pathogenesis of preeclampsiaQ28083676
Inhibition of Angiotensin II receptors during pregnancy induces malformations in developing rat kidneyQ28583780
Autoantibodies against the angiotensin receptor (AT1) in patients with hypertensionQ74126541
Circulating levels of immunoreactive cytokines in women with preeclampsiaQ77384781
The role of angiotensin II type 1 receptor-activating antibodies in renal allograft vascular rejectionQ79882539
Angiotensin II type 1 receptor agonistic antibodies reflect fundamental alterations in the uteroplacental vasculatureQ81423834
Hypertension in response to AT1-AA: role of reactive oxygen species in pregnancy-induced hypertensionQ83799951
Autoantibodies isolated from preeclamptic patients induce endothelial dysfunction via interaction with the angiotensin II AT1 receptorQ86521061
The detrimental role of angiotensin receptor agonistic autoantibodies in intrauterine growth restriction seen in preeclampsiaQ33591058
The role of inflammation in the pathology of preeclampsiaQ33834419
Patients with preeclampsia develop agonistic autoantibodies against the angiotensin AT1 receptorQ33848380
Exposure to AT1 receptor autoantibodies during pregnancy increases susceptibility of the maternal heart to postpartum ischemia-reperfusion injury in ratsQ34072217
Preeclampsia from a renal point of view: Insides into disease models, biomarkers and therapyQ34453242
Agonistic Autoantibodies to the Angiotensin II Type 1 Receptor Enhance Angiotensin II-Induced Renal Vascular Sensitivity and Reduce Renal Function During PregnancyQ34541831
Pregnancy and the risk of strokeQ34683028
Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysisQ34708320
Public health perspectives of preeclampsia in developing countries: implication for health system strengtheningQ34919890
Hypertensive diseases of pregnancy and risk of hypertension and stroke in later life: results from cohort studyQ34950435
Maternal treatment with agonistic autoantibodies against type-1 angiotensin II receptor in late pregnancy increases apoptosis of myocardial cells and myocardial susceptibility to ischemia-reperfusion injury in offspring ratsQ35053657
Regulation of soluble fms-like tyrosine kinase-1 production in response to placental ischemia/hypoxia: role of angiotensin II.Q35363716
Angiotensin II type 1 autoantibody induced hypertension during pregnancy is associated with renal endothelial dysfunctionQ35576417
Tumor necrosis factor alpha mRNA and protein are present in human placental and uterine cells at early and late stages of gestationQ35830416
Angiotensin II receptor antagonist treatment during pregnancyQ36019473
Autoantibody-mediated angiotensin receptor activation contributes to preeclampsia through tumor necrosis factor-alpha signalingQ36050771
A model of preeclampsia in rats: the reduced uterine perfusion pressure (RUPP) modelQ36115311
IL-17-mediated oxidative stress is an important stimulator of AT1-AA and hypertension during pregnancyQ36178540
Preeclampsia: recent insightsQ36288757
The effect of immune factors, tumor necrosis factor-alpha, and agonistic autoantibodies to the angiotensin II type I receptor on soluble fms-like tyrosine-1 and soluble endoglin production in response to hypertension during pregnancyQ36407259
Angiotensin II type 1 receptor antibodies and increased angiotensin II sensitivity in pregnant ratsQ36683260
Angiotensin II type 1 receptor autoantibody (AT1-AA)-mediated pregnancy hypertensionQ37353499
Endothelin-1, oxidative stress, and endogenous angiotensin II: mechanisms of angiotensin II type I receptor autoantibody-enhanced renal and blood pressure response during pregnancyQ37353537
Autoantibodies to the angiotensin type I receptor in response to placental ischemia and tumor necrosis factor alpha in pregnant ratsQ37436219
Hypertension in response to autoantibodies to the angiotensin II type I receptor (AT1-AA) in pregnant rats: role of endothelin-1.Q37447371
Role of IgM and angiotensin II Type I receptor autoantibodies in local complement activation in placental ischemia-induced hypertension in the rat.Q41653771
Losartan and fetal toxic effectsQ43531337
HELLP syndrome in the 18th week of gestation in association with elevated angiotensin AT(1)-receptor autoantibodiesQ43672726
Angiotensin II and cAMP regulate AT(1)-mRNA expression in rat cardiomyocytes by transcriptional mechanismQ44070519
Autoantibodies against AT1-receptor and alpha1-adrenergic receptor in patients with hypertensionQ44162378
AT1 receptor agonistic antibodies from preeclamptic patients stimulate NADPH oxidaseQ44385661
Agonistic autoantibodies directed against the angiotensin II AT1 receptor in patients with preeclampsiaQ44413491
Human fetal malformations associated with the use of an angiotensin II receptor antagonist: case reportQ44787814
Preeclampsia and the risk of end-stage renal diseaseQ45748808
Enhanced endothelin synthesis by endothelial cells exposed to sera from pregnant rats with decreased uterine perfusionQ46877931
Natural killer cells mediate pathophysiology in response to reduced uterine perfusion pressureQ47637232
Agonistic Angiotensin II Type 1 Receptor Autoantibodies in Postpartum Women With a History of PreeclampsiaQ56981931
AT(1) receptor agonistic antibodies from preeclamptic patients cause vascular cells to express tissue factorQ73815485
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectpre-eclampsiaQ61335
autoantibodyQ785022
pathophysiologyQ1135939
P304page(s)781-785
P577publication date2018-01-01
P1433published inCurrent Pharmaceutical BiotechnologyQ15763083
P1476titleThe role of Agonistic Autoantibodies to the Angiotensin II Type 1 Receptor (AT1-AA) in Pathophysiology of Preeclampsia
P478volume19

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