Autoantibody-mediated angiotensin receptor activation contributes to preeclampsia through tumor necrosis factor-alpha signaling

scientific article

Autoantibody-mediated angiotensin receptor activation contributes to preeclampsia through tumor necrosis factor-alpha signaling is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1161/HYPERTENSIONAHA.110.150540
P932PMC publication ID3380607
P698PubMed publication ID20351341

P50authorSusan M. RaminQ110252023
P2093author name stringYang Xia
Yujin Zhang
M John Hicks
Rodney E Kellems
Roxanna A Irani
Sean C Blackwell
Cissy Chenyi Zhou
P2860cites workBiological functions of angiotensin and its receptorsQ28306268
Tumor necrosis factor induces glomerular damage in the rabbitQ33444321
The detrimental role of angiotensin receptor agonistic autoantibodies in intrauterine growth restriction seen in preeclampsiaQ33591058
TNF-alpha inhibition reduces renal injury in DOCA-salt hypertensive ratsQ33647618
Angiotensin receptor agonistic autoantibody is highly prevalent in preeclampsia: correlation with disease severityQ33748680
Patients with preeclampsia develop agonistic autoantibodies against the angiotensin AT1 receptorQ33848380
Pathogenesis and genetics of pre-eclampsiaQ33934445
Human pro-tumor necrosis factor is a homotrimerQ34386603
Latest advances in understanding preeclampsiaQ34425288
Angiotensin II induces soluble fms-Like tyrosine kinase-1 release via calcineurin signaling pathway in pregnancyQ35699115
Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant miceQ35701236
Immunosuppressive treatment protects against angiotensin II-induced renal damageQ35747734
Endothelin, the kidney, and hypertensionQ36554955
The role of the immune system in preeclampsiaQ36791219
NK cells and pre-eclampsiaQ36812227
Experimental elimination of tumor necrosis factor in low-dose endotoxin models has variable effects on survivalQ36966855
Pathophysiology of hypertension during preeclampsia: linking placental ischemia with endothelial dysfunctionQ37022723
Inflammatory cytokines in the pathophysiology of hypertension during preeclampsiaQ37119326
Cellular localization of AT1 receptor mRNA and protein in normal placenta and its reduced expression in intrauterine growth restriction. Angiotensin II stimulates the release of vasorelaxantsQ37377636
Hypertension in response to chronic reductions in uterine perfusion in pregnant rats: effect of tumor necrosis factor-alpha blockadeQ37459545
Vasoactive peptides and uterine vesselsQ40383652
Angiotensin receptor subtype AT(1) mediates alveolar epithelial cell apoptosis in response to ANG II.Q40746660
Interleukin-12 augments cytolytic activity of peripheral and decidual lymphocytes against choriocarcinoma cell lines and primary culture human placental trophoblastsQ40946626
Angiotensin II induces apoptosis in human and rat alveolar epithelial cellsQ40954053
Chimeric anti-TNF-α monoclonal antibody cA2 binds recombinant transmembrane TNF-α and activates immune effector functionsQ41355139
Placental cytokines and the pathogenesis of preeclampsiaQ41452017
Angiotensin II signal transduction in vascular smooth muscle: role of tyrosine kinasesQ41454874
Angiotensin II induces tumor necrosis factor biosynthesis in the adult mammalian heart through a protein kinase C-dependent pathwayQ43982318
Differential effects between marimastat, a TNF-alpha converting enzyme inhibitor, and anti-TNF-alpha antibody on murine models for sepsis and arthritisQ44025492
TNF-alpha enhances contraction and inhibits endothelial NO-cGMP relaxation in systemic vessels of pregnant ratsQ44031650
Angiotensin II regulates the synthesis of proinflammatory cytokines and chemokines in the kidney.Q44201217
Autoantibody against AT1 receptor from preeclamptic patients induces vasoconstriction through angiotensin receptor activationQ44218760
Maternal autoantibodies from preeclamptic patients activate angiotensin receptors on human trophoblast cellsQ44320558
AT1 receptor agonistic antibodies from preeclamptic patients stimulate NADPH oxidaseQ44385661
Angiotensin II-induced MMP-2 release from endothelial cells is mediated by TNF-alphaQ44673765
Antibodies from preeclamptic patients stimulate increased intracellular Ca2+ mobilization through angiotensin receptor activationQ45069619
Maternal autoantibodies from preeclamptic patients activate angiotensin receptors on human mesangial cells and induce interleukin-6 and plasminogen activator inhibitor-1 secretionQ46344658
Protein kinase-mediated regulation of calcineurin through the phosphorylation of modulatory calcineurin-interacting protein 1.Q46895776
Angiotensin II participates in mononuclear cell recruitment in experimental immune complex nephritis through nuclear factor-kappa B activation and monocyte chemoattractant protein-1 synthesis.Q47909651
Elevated placental soluble vascular endothelial growth factor receptor-1 inhibits angiogenesis in preeclampsiaQ47915288
Cytotoxicity of tumour necrosis factor-alpha and gamma-interferon against primary human placental trophoblasts.Q50767140
Negative regulation of soluble Flt-1 and soluble endoglin release by heme oxygenase-1.Q51037240
Raised serum TNF-alpha, blood sugar and uric acid in preeclampsia in third trimester of pregnancy.Q51501322
Evidence for a role of tumor necrosis factor alpha in disturbances of triglyceride and glucose metabolism predisposing to coronary heart disease.Q51572038
Role of endothelin in mediating tumor necrosis factor-induced hypertension in pregnant rats.Q54661322
Evidence for an elevation in serum interleukin-2 and tumor necrosis factor-alpha levels before the clinical manifestations of preeclampsiaQ73628337
AT(1) receptor agonistic antibodies from preeclamptic patients cause vascular cells to express tissue factorQ73815485
Report of the National High Blood Pressure Education Program Working Group on High Blood Pressure in PregnancyQ74090763
Angiotensin II induces TNF production by the thick ascending limb: functional implicationsQ74154109
Definitive molecular evidence of renin-angiotensin system in human uterine decidual cellsQ74188076
Circulating levels of immunoreactive cytokines in women with preeclampsiaQ77384781
Angiotensin II decreases system A amino acid transporter activity in human placental villous fragments through AT1 receptor activationQ79760387
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectautoantibodyQ785022
pre-eclampsiaQ61335
P304page(s)1246-1253
P577publication date2010-03-29
P1433published inHypertensionQ5958695
P1476titleAutoantibody-mediated angiotensin receptor activation contributes to preeclampsia through tumor necrosis factor-alpha signaling
P478volume55

Reverse relations

cites work (P2860)
Q28069689A Dormant Microbial Component in the Development of Preeclampsia
Q27003069A leading role for the immune system in the pathophysiology of preeclampsia
Q34870775A2B adenosine receptor-mediated induction of IL-6 promotes CKD.
Q38118625Activating autoantibodies and cardiovascular disease
Q64111458Angiotensin II type i receptor agonistic autoantibodies induces apoptosis of cardiomyocytes by downregulating miR21 in preeclampsia: a mechanism study
Q27027039Angiotensin receptor agonistic autoantibodies and hypertension: preeclampsia and beyond
Q37816496Animal models of pre-eclampsia.
Q26828588Antibodies in the pathogenesis of hypertension
Q107324240Autoantibodies against ACE2 and angiotensin type-1 receptors increase severity of COVID-19
Q35715914Autoantibody-mediated IL-6-dependent endothelin-1 elevation underlies pathogenesis in a mouse model of preeclampsia
Q34040357Autoantibody-mediated complement C3a receptor activation contributes to the pathogenesis of preeclampsia
Q36334105Beneficial effect of human umbilical cord-derived mesenchymal stem cells on an endotoxin-induced rat model of preeclampsia
Q45020552Differential regulation of TNF receptors in maternal leukocytes is associated with severe preterm preeclampsia
Q36836373Elevated Transglutaminase Activity Triggers Angiotensin Receptor Activating Autoantibody Production and Pathophysiology of Preeclampsia
Q26852668Elucidating immune mechanisms causing hypertension during pregnancy
Q33577570Endothelial dysfunction induced by antibodies against angiotensin AT1 receptor in immunized rats
Q34072217Exposure to AT1 receptor autoantibodies during pregnancy increases susceptibility of the maternal heart to postpartum ischemia-reperfusion injury in rats
Q34656228Foxp3 (-/ATT) polymorphism contributes to the susceptibility of preeclampsia
Q35362708Full-length human placental sFlt-1-e15a isoform induces distinct maternal phenotypes of preeclampsia in mice
Q36380039GPCRs as potential therapeutic targets in preeclampsia.
Q83799951Hypertension in response to AT1-AA: role of reactive oxygen species in pregnancy-induced hypertension
Q35029700Hypertension in response to placental ischemia during pregnancy: role of B lymphocytes
Q37786350Immunologic characteristics of preeclampsia, a comprehensive review
Q89860687Inflammasomes-A Molecular Link for Altered Immunoregulation and Inflammation Mediated Vascular Dysfunction in Preeclampsia
Q39198610Inflammation, Autoimmunity, and Hypertension: The Essential Role of Tissue Transglutaminase
Q26827525Inflammation, immunity, and hypertensive end-organ damage
Q38543831Linking the old and new -- do angiotensin II type 1 receptor antibodies provide the missing link in the pathophysiology of preeclampsia?
Q55004295Maternal plasma fetuin-A concentration is lower in patients who subsequently developed preterm preeclampsia than in uncomplicated pregnancy: a longitudinal study.
Q34495512Maternal serum levels of TNF-alpha and IL-6 long after delivery in preeclamptic and normotensive pregnant women
Q34140082Maternally sequestered therapeutic polypeptides - a new approach for the management of preeclampsia
Q50937792Mechanism of agonistic angiotensin II type I receptor autoantibody-amplified contractile response to Ang II in the isolated rat thoracic aorta.
Q35099504Mesenchymal stem cells ameliorate Th1-induced pre-eclampsia-like symptoms in mice via the suppression of TNF-α expression
Q54901493Molecular Mechanisms of Preeclampsia.
Q33891299Morphometric evaluation of preeclamptic placenta using light microscopic images
Q37451544Placental Ischemia and Resultant Phenotype in Animal Models of Preeclampsia
Q39136791Recent Advances in Immunity and Hypertension
Q35707881Receptor-activating autoantibodies and disease: preeclampsia and beyond
Q35683468Recombinant vascular endothelial growth factor 121 attenuates autoantibody-induced features of pre-eclampsia in pregnant mice
Q64907090Renin-angiotensin system in pre-eclampsia: everything old is new again.
Q47546316Role and mechanism of AT1-AA in the pathogenesis of HELLP syndrome
Q37067705Role of agonistic autoantibodies against type-1 angiotensin II receptor in the pathogenesis of retinopathy in preeclampsia
Q38014802The pathophysiology of preeclampsia involves altered levels of angiogenic factors promoted by hypoxia and autoantibody-mediated mechanisms
Q57150158The role of Agonistic Autoantibodies to the Angiotensin II Type 1 Receptor (AT1-AA) in Pathophysiology of Preeclampsia
Q33834419The role of inflammation in the pathology of preeclampsia
Q33668328The therapeutic potential of antioxidants, ER chaperones, NO and H2S donors, and statins for treatment of preeclampsia
Q48284671Therapeutic benefit of mesenchymal stem cells in pregnant rats with angiotensin receptor agonistic autoantibody-induced hypertension: Implications for immunomodulation and cytoprotection.
Q36836229Tumor necrosis factor-α: regulation of renal function and blood pressure

Search more.