Linking the old and new -- do angiotensin II type 1 receptor antibodies provide the missing link in the pathophysiology of preeclampsia?

scientific article published on 08 July 2015

Linking the old and new -- do angiotensin II type 1 receptor antibodies provide the missing link in the pathophysiology of preeclampsia? is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.3109/10641955.2015.1051227
P698PubMed publication ID26153629

P50authorAnnemarie HennessyQ37837597
Angela MakrisQ76380588
Shikha AggarwalQ114573414
P2860cites workA leading role for the immune system in the pathophysiology of preeclampsiaQ27003069
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Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsiaQ29615916
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The detrimental role of angiotensin receptor agonistic autoantibodies in intrauterine growth restriction seen in preeclampsiaQ33591058
Angiotensin receptor agonistic autoantibody-mediated tumor necrosis factor-alpha induction contributes to increased soluble endoglin production in preeclampsiaQ33748650
Angiotensin receptor agonistic autoantibody is highly prevalent in preeclampsia: correlation with disease severityQ33748680
Patients with preeclampsia develop agonistic autoantibodies against the angiotensin AT1 receptorQ33848380
Pathogenesis and genetics of pre-eclampsiaQ33934445
Angiotensin receptor agonistic autoantibody-mediated soluble fms-like tyrosine kinase-1 induction contributes to impaired adrenal vasculature and decreased aldosterone production in preeclampsiaQ34040304
Recent Insights into the pathogenesis of pre-eclampsiaQ34682287
Cardiovascular sequelae of preeclampsia/eclampsia: a systematic review and meta-analysesQ34897462
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Autoantibody from women with preeclampsia induces soluble Fms-like tyrosine kinase-1 production via angiotensin type 1 receptor and calcineurin/nuclear factor of activated T-cells signalingQ35681804
Recombinant vascular endothelial growth factor 121 attenuates autoantibody-induced features of pre-eclampsia in pregnant miceQ35683468
Autoantibody-mediated IL-6-dependent endothelin-1 elevation underlies pathogenesis in a mouse model of preeclampsiaQ35715914
Placental oxidative stress: from miscarriage to preeclampsiaQ35879133
Autoantibody-mediated angiotensin receptor activation contributes to preeclampsia through tumor necrosis factor-alpha signalingQ36050771
IL-17-mediated oxidative stress is an important stimulator of AT1-AA and hypertension during pregnancyQ36178540
Hypertension in response to IL-6 during pregnancy: role of AT1-receptor activationQ36244980
Agonistic antibodies directed at the angiotensin II, AT1 receptor in preeclampsiaQ36380482
The effect of immune factors, tumor necrosis factor-alpha, and agonistic autoantibodies to the angiotensin II type I receptor on soluble fms-like tyrosine-1 and soluble endoglin production in response to hypertension during pregnancyQ36407259
Immunoregulation in normal pregnancy and pre-eclampsia: an overviewQ36684096
Hypoxia and reoxygenation: a possible mechanism for placental oxidative stress in preeclampsiaQ36686796
The functional role of the renin-angiotensin system in pregnancy and preeclampsiaQ37039872
Protein composition of microparticles shed from human placenta during placental perfusion: Potential role in angiogenesis and fibrinolysis in preeclampsiaQ37146239
Autoantibodies to the angiotensin type I receptor in response to placental ischemia and tumor necrosis factor alpha in pregnant ratsQ37436219
Hypertension in response to autoantibodies to the angiotensin II type I receptor (AT1-AA) in pregnant rats: role of endothelin-1.Q37447371
The pathophysiology of preeclampsia involves altered levels of angiogenic factors promoted by hypoxia and autoantibody-mediated mechanismsQ38014802
The role of hypoxia and hypoxia-inducible factor-1alpha in preeclampsia pathogenesisQ38049205
Vascular endothelial growth factor-A and aldosterone: relevance to normal pregnancy and preeclampsiaQ39185420
Regulation of placental growth by aldosterone and cortisolQ39633468
Control of vascular responsiveness during human pregnancyQ40122647
Sera from preeclamptic women specifically activate human umbilical vein endothelial cells in vitro: morphological and biochemical evidenceQ41098649
Preeclampsia: an endothelial cell disorderQ41281924
Placental cytokines and the pathogenesis of preeclampsiaQ41452017
Lymphocyte intracellular free calcium concentration is increased in preeclampsiaQ42472176
Hypertension Induced by the Tyrosine Kinase Inhibitor Sunitinib Is Associated With Increased Circulating Endothelin-1 LevelsQ42928512
Study of plasma factors associated with neutrophil activation and lipid peroxidation in preeclampsiaQ43771322
Angiotensin type 1 receptor autoantibody from preeclamptic patients induces human fetoplacental vasoconstrictionQ43939628
Autoantibody against AT1 receptor from preeclamptic patients induces vasoconstriction through angiotensin receptor activationQ44218760
Maternal autoantibodies from preeclamptic patients activate angiotensin receptors on human trophoblast cellsQ44320558
AT1 receptor agonistic antibodies from preeclamptic patients stimulate NADPH oxidaseQ44385661
Agonistic autoantibodies directed against the angiotensin II AT1 receptor in patients with preeclampsiaQ44413491
Antibodies from preeclamptic patients stimulate increased intracellular Ca2+ mobilization through angiotensin receptor activationQ45069619
Angiotensin II type 1-receptor activating antibodies in renal-allograft rejectionQ45259438
Increased intracellular free calcium and sensitivity to angiotensin II in platelets of preeclamptic womenQ46136176
Uteroplacental ischemia results in proteinuric hypertension and elevated sFLT-1.Q46339760
Maternal autoantibodies from preeclamptic patients activate angiotensin receptors on human mesangial cells and induce interleukin-6 and plasminogen activator inhibitor-1 secretionQ46344658
Recognition of the long-term sequelae of eclampsiaQ50246480
Hypertension produced by reductions in uterine perfusion in the pregnant rat: role of tumor necrosis factor-alpha.Q51359651
Involvement of functional autoantibodies against vascular receptors in systemic sclerosis.Q52900457
Immunology in hypertension, preeclampsia, and target-organ damage.Q52909791
Role of endothelin in mediating tumor necrosis factor-induced hypertension in pregnant rats.Q54661322
Prevalence of agonistic autoantibodies against the angiotensin II type 1 receptor and soluble fms-like tyrosine kinase 1 in a gestational age-matched case study.Q54782424
Agonistic Angiotensin II Type 1 Receptor Autoantibodies in Postpartum Women With a History of PreeclampsiaQ56981931
P433issue3
P921main subjectpre-eclampsiaQ61335
maternal healthQ6786626
P304page(s)369-382
P577publication date2015-07-08
P1433published inHypertension in PregnancyQ5958696
P1476titleLinking the old and new -- do angiotensin II type 1 receptor antibodies provide the missing link in the pathophysiology of preeclampsia?
P478volume34

Reverse relations

Q39737548Anti-Angiotensin II Type 1 Receptor and Anti-Endothelial Cell Antibodies: A Cross-Sectional Analysis of Pathological Findings in Allograft Biopsiescites workP2860

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