Angiotensin II type i receptor agonistic autoantibodies induces apoptosis of cardiomyocytes by downregulating miR21 in preeclampsia: a mechanism study

Angiotensin II type i receptor agonistic autoantibodies induces apoptosis of cardiomyocytes by downregulating miR21 in preeclampsia: a mechanism study is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID6511800
P698PubMed publication ID31105840

P2093author name stringJin Wang
Jiping Yue
Jianming Zhi
Qin Xia
Xiangying Jiao
P2860cites workMicroRNA expression in response to murine myocardial infarction: miR-21 regulates fibroblast metalloprotease-2 via phosphatase and tensin homologueQ24643939
Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosisQ24798477
MicroRNA-21 is a downstream effector of AKT that mediates its antiapoptotic effects via suppression of Fas ligandQ28509297
Human villous trophoblasts express and secrete placenta-specific microRNAs into maternal circulation via exosomesQ33459716
Patients with preeclampsia develop agonistic autoantibodies against the angiotensin AT1 receptorQ33848380
Exposure to AT1 receptor autoantibodies during pregnancy increases susceptibility of the maternal heart to postpartum ischemia-reperfusion injury in ratsQ34072217
MicroRNAs: small RNAs with big effectsQ34979843
Maternal treatment with agonistic autoantibodies against type-1 angiotensin II receptor in late pregnancy increases apoptosis of myocardial cells and myocardial susceptibility to ischemia-reperfusion injury in offspring ratsQ35053657
Up-regulation of microRNA-21 mediates isoflurane-induced protection of cardiomyocytes.Q35196236
Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant miceQ35701236
Autoantibody-mediated angiotensin receptor activation contributes to preeclampsia through tumor necrosis factor-alpha signalingQ36050771
The functional role of the renin-angiotensin system in pregnancy and preeclampsiaQ37039872
Role of agonistic autoantibodies against type-1 angiotensin II receptor in the pathogenesis of retinopathy in preeclampsiaQ37067705
PTEN and the PI3-kinase pathway in cancerQ37259680
MicroRNA analysis in placentas from patients with preeclampsia: comparison of new and published resultsQ38120774
Functional, structural, and sequence studies of microRNA.Q38165850
The potential for circulating microRNAs in the diagnosis of myocardial infarction: a novel approach to disease diagnosis and treatmentQ38631508
Circulating microRNAs and hypertension--from new insights into blood pressure regulation to biomarkers of cardiovascular riskQ38716878
Role of IgM and angiotensin II Type I receptor autoantibodies in local complement activation in placental ischemia-induced hypertension in the rat.Q41653771
MicroRNA expression profiles in placenta with severe preeclampsia using a PNA-based microarrayQ45238170
Mechanism of agonistic angiotensin II type I receptor autoantibody-amplified contractile response to Ang II in the isolated rat thoracic aorta.Q50937792
Downregulation of microRNA‑21 expression inhibits proliferation, and induces G1 arrest and apoptosis via the PTEN/AKT pathway in SKM‑1 cells.Q64930094
AT(1) receptor agonistic antibodies from preeclamptic patients cause vascular cells to express tissue factorQ73815485
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectpre-eclampsiaQ61335
cardiomyocyteQ1047227
P304page(s)2339-2349
P577publication date2019-01-01
P1433published inAmerican Journal of Translational ResearchQ4744272
P1476titleAngiotensin II type i receptor agonistic autoantibodies induces apoptosis of cardiomyocytes by downregulating miR21 in preeclampsia: a mechanism study
P478volume11

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Q98289716Phosphoproteomics reveals the apoptotic regulation of aspirin in the placenta of preeclampsia-like micecites workP2860

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