Endothelial dysfunction. An important mediator in the pathophysiology of hypertension during pre-eclampsia

scientific article published on August 2012

Endothelial dysfunction. An important mediator in the pathophysiology of hypertension during pre-eclampsia is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID3796355
P698PubMed publication ID22728575

P2093author name stringB Lamarca
P2860cites workEicosanoids in preeclampsiaQ28166550
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Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsiaQ29615916
Changes in endothelial function precede the clinical disease in women in whom preeclampsia developsQ33225347
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Patients with preeclampsia develop agonistic autoantibodies against the angiotensin AT1 receptorQ33848380
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CD4+ T-helper cells stimulated in response to placental ischemia mediate hypertension during pregnancyQ35130793
Preeclampsia, a disease of the maternal endothelium: the role of antiangiogenic factors and implications for later cardiovascular diseaseQ35143007
Angiotensin II type 1 autoantibody induced hypertension during pregnancy is associated with renal endothelial dysfunctionQ35576417
Heme Oxygenase-1 Attenuates Hypoxia-Induced sFlt-1 and Oxidative Stress in Placental Villi through Its Metabolic Products CO and BilirubinQ35615008
Potential roles of angiotensin receptor-activating autoantibody in the pathophysiology of preeclampsiaQ35681821
Oxidative stress and preeclampsia: rationale for antioxidant clinical trialsQ35869763
L-arginine supplementation abolishes the blood pressure and endothelin response to chronic increases in plasma sFlt-1 in pregnant ratsQ35950303
Activating autoantibodies to the angiotensin II type I receptor play an important role in mediating hypertension in response to adoptive transfer of CD4+ T lymphocytes from placental ischemic ratsQ35994304
Role of the renin-angiotensin system in the pathogenesis of preeclampsiaQ36064478
Preeclampsia serum upregulates CD40/CD40L expression and induces apoptosis in human umbilical cord endothelial cellsQ36112505
Hypertension in response to CD4(+) T cells from reduced uterine perfusion pregnant rats is associated with activation of the endothelin-1 system.Q36115279
Hypertension in response to IL-6 during pregnancy: role of AT1-receptor activationQ36244980
Preeclampsia: recent insightsQ36288757
Agonistic autoantibodies to the angiotensin II type I receptor cause pathophysiologic characteristics of preeclampsiaQ36355165
Angiotensin II type 1 receptor antibodies and increased angiotensin II sensitivity in pregnant ratsQ36683260
Immunoregulation in normal pregnancy and pre-eclampsia: an overviewQ36684096
Pathophysiology of hypertension in response to placental ischemia during pregnancy: a central role for endothelin?Q37131819
First trimester vitamin D, vitamin D binding protein, and subsequent preeclampsiaQ37178546
Elevated asymmetric dimethylarginine concentrations precede clinical preeclampsia, but not pregnancies with small-for-gestational-age infantsQ37181052
Hypertension in response to autoantibodies to the angiotensin II type I receptor (AT1-AA) in pregnant rats: role of endothelin-1.Q37447371
Endothelial dysfunction: a link among preeclampsia, recurrent pregnancy loss, and future cardiovascular events?Q40268212
Preeclampsia: an endothelial cell disorderQ41281924
Importance of prostaglandins in hypertension during reduced uteroplacental perfusion pressureQ41284596
Placental cytokines and the pathogenesis of preeclampsiaQ41452017
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Reduced uterine perfusion pressure during pregnancy in the rat is associated with increases in arterial pressure and changes in renal nitric oxide.Q43576536
Pathophysiology of hypertension during preeclampsia linking placental ischemia with endothelial dysfunctionQ43744794
Enhanced thromboxane synthesis during chronic reductions in uterine perfusion pressure in pregnant ratsQ44130345
Reduced endothelial NO-cGMP-mediated vascular relaxation and hypertension in IL-6-infused pregnant ratsQ44715072
L-arginine depletion in preeclampsia orients nitric oxide synthase toward oxidant speciesQ44743355
Cytochrome P-450 inhibition attenuates hypertension induced by reductions in uterine perfusion pressure in pregnant ratsQ44752496
L-arginine attenuates hypertension in pregnant rats with reduced uterine perfusion pressureQ44760481
TNF alpha concentrations and mRNA expression are increased in preeclamptic placentasQ45102738
Maternal-placental interactions of oxidative stress and antioxidants in preeclampsiaQ45112360
Low-molecular-weight heparin lowers the recurrence rate of preeclampsia and restores the physiological vascular changes in angiotensin-converting enzyme DD womenQ45158743
S-nitrosoalbumin-mediated relaxation is enhanced by ascorbate and copper: effects in pregnancy and preeclampsia plasmaQ45166655
Lectin-like oxidized low-density lipoprotein 1 receptor in a reduced uteroplacental perfusion pressure rat model of preeclampsiaQ46324781
Systemic increase in the ratio between Foxp3+ and IL-17-producing CD4+ T cells in healthy pregnancy but not in preeclampsiaQ46332630
Circulating factors as markers and mediators of endothelial cell dysfunction in preeclampsiaQ46433836
System y+ arginine transport and NO production in peripheral blood mononuclear cells in pregnancy and preeclampsiaQ46847905
Pregnancy prevents hypertensive remodeling of cerebral arteries: a potential role in the development of eclampsiaQ46870281
Enhanced endothelin synthesis by endothelial cells exposed to sera from pregnant rats with decreased uterine perfusionQ46877931
Women with preeclampsia have higher plasma endothelin levels than women with normal pregnanciesQ46878600
Moderate ascorbate deficiency increases myogenic tone of arteries from pregnant but not virgin ascorbate-dependent ratsQ46907903
Insulin resistance in preeclampsiaQ46919162
Implication of an AGT haplotype in a multigene association study with pregnancy hypertensionQ47364068
Preeclampsia is associated with lower percentages of regulatory T cells in maternal bloodQ47890265
Insulin resistance and alterations in angiogenesis: additive insults that may lead to preeclampsiaQ47945074
Decreased endothelium-dependent vascular relaxation during reduction of uterine perfusion pressure in pregnant rat.Q50514586
Hypertension produced by reductions in uterine perfusion in the pregnant rat: role of interleukin 6.Q51139503
Hypertension produced by reductions in uterine perfusion in the pregnant rat: role of tumor necrosis factor-alpha.Q51359651
Lipoprotein subfraction changes in normal pregnancy: threshold effect of plasma triglyceride on appearance of small, dense low density lipoprotein.Q51574204
Fatty acid pattern of esterified and free fatty acids in sera of women with normal and pre‐eclamptic pregnancyQ51587356
Short- and long-term changes in plasma inflammatory markers associated with preeclampsia.Q52087250
Relation between circulating angiotensin II type 1 receptor agonistic autoantibodies and soluble fms-like tyrosine kinase 1 in the pathogenesis of preeclampsia.Q52933863
Agonistic autoantibodies to the AT1 receptor in a transgenic rat model of preeclampsia.Q52940276
Soluble endoglin and other circulating antiangiogenic factors in preeclampsia.Q53600812
Role of endothelin in mediating tumor necrosis factor-induced hypertension in pregnant rats.Q54661322
Agonistic Angiotensin II Type 1 Receptor Autoantibodies in Postpartum Women With a History of PreeclampsiaQ56981931
Dysregulation of the Circulating and Tissue-Based Renin-Angiotensin System in PreeclampsiaQ56981959
In Preeclampsia, the Circulating Factors Capable of Altering In Vitro Endothelial Function Precede Clinical DiseaseQ58035998
Changes in Endothelial Function Precede the Clinical Disease in Women in Whom Preeclampsia DevelopsQ61830910
Cardiovascular Function in Mice During Normal Pregnancy and in the Absence of Endothelial NO SynthaseQ61964364
The effect of over-expression of sFlt-1 on blood pressure and the occurrence of other manifestations of preeclampsia in unrestrained conscious pregnant miceQ64377179
Maternal plasma level of endothelin is increased in preeclampsiaQ67973452
Maternal and fetal serum nitric oxide (NO) concentrations in normal pregnancy, pre-eclampsia and eclampsiaQ73502640
Endothelin type a receptor blockade attenuates the hypertension in response to chronic reductions in uterine perfusion pressureQ73567364
Nitric oxide production with preeclampsiaQ74601245
Plasma lipids and vascular dysfunction in preeclampsiaQ74757931
Plasma and 24-h NO(x) and cGMP during normal pregnancy and preeclampsia in women on a reduced NO(x) dietQ78009520
Maternal fetal/placental interactions and abnormal pregnancy outcomesQ79372322
Difference in neutrophil superoxide generation during pregnancy between preeclampsia and essential hypertensionQ80125849
Questionable role of the angiotensin II receptor subtype 1 autoantibody in the pathogenesis of preeclampsiaQ80336129
Generation of reactive oxygen species by neutrophils and endothelial cell injury in normal and preeclamptic pregnanciesQ81236313
Hypertension during pregnancy: a disorder begging for pathophysiological supportQ81397976
Angiotensin II type 1 receptor agonistic antibodies reflect fundamental alterations in the uteroplacental vasculatureQ81423834
Uterine artery Doppler and changes in endothelial function before clinical disease in preeclamptic womenQ82615541
P433issue4
P921main subjectmaternal healthQ6786626
arterial hypertensionQ41861
pre-eclampsiaQ61335
endotheliumQ111140
pathophysiologyQ1135939
P304page(s)309-320
P577publication date2012-08-01
P1433published inMinerva GinecologicaQ15752699
P1476titleEndothelial dysfunction. An important mediator in the pathophysiology of hypertension during pre-eclampsia
P478volume64

Reverse relations

cites work (P2860)
Q92180156A cross sectional study to assess the sFlt-1:PlGF ratio in pregnant women with and without preeclampsia
Q53700889AT1-AA (Angiotensin II Type 1 Receptor Agonistic Autoantibody) Blockade Prevents Preeclamptic Symptoms in Placental Ischemic Rats.
Q38684330Dysregulation of the Fas/FasL system in an experimental animal model of HELLP syndrome.
Q35547367Endocan, a putative endothelial cell marker, is elevated in preeclampsia, decreased in acute pyelonephritis, and unchanged in other obstetrical syndromes
Q37512393Endothelin-1 down-regulates matrix metalloproteinase 14 and 15 expression in human first trimester trophoblasts via endothelin receptor type B.
Q35800606Expression profile of C19MC microRNAs in placental tissue in pregnancy-related complications
Q42679579Expression profile of C19MC microRNAs in placental tissue of patients with preterm prelabor rupture of membranes and spontaneous preterm birth.
Q98613250Family history of chronic illness, preterm gestational age and smoking exposure before pregnancy increases the probability of preeclampsia in Omo district in southern Ethiopia: a case-control study
Q35979122Heart Rate Variability and Autonomic Modulations in Preeclampsia
Q34025660Hypertension, inflammation and T lymphocytes are increased in a rat model of HELLP syndrome
Q88503866Impaired function of cerebral parenchymal arterioles in experimental preeclampsia
Q55223615Int6/eIF3e Silencing Promotes Placenta Angiogenesis in a Rat Model of Pre-eclampsia.
Q35690758Involvement of Visceral Adipose Tissue in Immunological Modulation of Inflammatory Cascade in Preeclampsia
Q35883182Is the serum l-arginine level during early pregnancy a predictor of pregnancy-induced hypertension?
Q91962935Natural killer cells contribute to mitochondrial dysfunction in response to placental ischemia in reduced uterine perfusion pressure rats
Q64226376Placental CX3CL1 is Deregulated by Angiotensin II and Contributes to a Pro-Inflammatory Trophoblast-Monocyte Interaction
Q57177277Preeclampsia and Related Cardiovascular Risk: Common Genetic Background
Q36838343Preeclampsia is a biomarker for vascular disease in both mother and child: the need for a medical alert system
Q26800272Preeclampsia: long-term consequences for vascular health
Q41387285Red cell distribution width predicts incident dipstick albuminuria in Korean adults without chronic kidney disease
Q50102668The profiles of soluble adhesion molecules in the "great obstetrical syndromes".
Q51294484Vitamin D supplementation reduces some AT1-AA-induced downstream targets implicated in preeclampsia including hypertension.

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