Circulating and Vascular Bioactive Factors during Hypertension in Pregnancy

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Circulating and Vascular Bioactive Factors during Hypertension in Pregnancy is …
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P356DOI10.2174/157340710790711737
P932PMC publication ID2856945
P698PubMed publication ID20419111
P5875ResearchGate publication ID43343448

P2093author name stringRaouf A Khalil
Alain F Tanbe
P2860cites workNitric oxide activity in the peripheral vasculature during normotensive and preeclamptic pregnancyQ78117582
Arachidonic acid metabolites and an early stage of pulmonary hypertension in chronically hypoxic newborn pigsQ78396702
Angiotensin-(1-7) in normal and preeclamptic pregnancyQ78568866
Evaluation of physiological alterations of the placenta through analysis of cell-free messenger ribonucleic acid concentrations of angiogenic factorsQ80425329
Serum levels of interleukin-6, interleukin-1beta and human chorionic gonadotropin in pre-eclamptic and normal pregnancyQ80454204
Recent patents on Rho signaling pathway as therapeutic target for cardiovascular diseasesQ80551190
The immunohistochemical evaluation of VEGF in placenta biopsies of pregnancies complicated by preeclampsiaQ80821578
Relationship between increased blood lead and pregnancy hypertension in women without occupational lead exposure in Tehran, IranQ80991877
Hypoxia is responsible for soluble vascular endothelial growth factor receptor-1 (VEGFR-1) but not for soluble endoglin induction in villous trophoblastQ81086992
Generation of reactive oxygen species by neutrophils and endothelial cell injury in normal and preeclamptic pregnanciesQ81236313
Screening test for preeclampsia through assessment of uteroplacental blood flow and biochemical markers of oxidative stress and endothelial dysfunctionQ81305565
Hypertension produced by reduced uterine perfusion in pregnant rats is associated with increased soluble fms-like tyrosine kinase-1 expressionQ81411178
Tumor necrosis factor-alpha in the placenta is not elevated in pre-eclamptic patients despite its elevation in peripheral bloodQ81432957
Angiotensin II hypertension is attenuated in interleukin-6 knockout miceQ81472565
Dietary fiber, potassium, magnesium and calcium in relation to the risk of preeclampsiaQ81878607
Antihypertensive drug therapy for mild to moderate hypertension during pregnancyQ24246376
Maternal obesity and diabetes as risk factors for adverse pregnancy outcomes: differences among 4 racial/ethnic groupsQ24544895
The placental problem: linking abnormal cytotrophoblast differentiation to the maternal symptoms of preeclampsiaQ24795491
Antioxidant therapy to prevent preeclampsiaQ28171421
Aspirin for the prevention of preeclampsia in women with abnormal uterine artery Doppler: a meta-analysisQ28191497
Aspirin for prevention of preeclampsia in women with historical risk factors: a systematic reviewQ28196410
Soluble endoglin contributes to the pathogenesis of preeclampsiaQ28244053
Aortic adaptation to pregnancy: elevated expression of matrix metalloproteinases-2 and -3 in rat gestationQ28574980
Impaired angiogenesis in SHR is associated with decreased KDR and MT1-MMP expressionQ28582505
Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functionsQ29547189
Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsiaQ29615916
Interleukin-6 induces oxidative stress and endothelial dysfunction by overexpression of the angiotensin II type 1 receptorQ30747560
Endothelin and nitric oxide mediate reduced myogenic reactivity of small renal arteries from pregnant ratsQ31731441
[Ca(2+)](i) signaling in renal arterial smooth muscle cells of pregnant rat is enhanced during inhibition of NOS.Q31732247
Role of endothelin B receptors in enhancing endothelium-dependent nitric oxide-mediated vascular relaxation during high salt dietQ32071788
Prolonged blockade of nitric oxide synthesis in gravid rats produces sustained hypertension, proteinuria, thrombocytopenia, and intrauterine growth retardationQ33490821
Endothelial cell responses to hypoxic stressQ33535019
Regulation of cardiovascular development and physiology by hypoxia-inducible factor 1.Q33692449
Patients with preeclampsia develop agonistic autoantibodies against the angiotensin AT1 receptorQ33848380
Molecular regulation of the endothelin-1 gene by hypoxia. Contributions of hypoxia-inducible factor-1, activator protein-1, GATA-2, AND p300/CBP.Q33940517
Vascular function in preeclampsia.Q33951685
Recurrence of pre-eclampsia across generations: exploring fetal and maternal genetic components in a population based cohortQ34081523
Nitric oxide regulates the expression of vasoconstrictors and growth factors by vascular endothelium under both normoxia and hypoxiaQ34110398
Protein kinase C isoforms as specific targets for modulation of vascular smooth muscle function in hypertensionQ34293890
Angiotensin and cytoskeletal proteins: role in vascular remodelingQ34492824
World Health Organization randomized trial of calcium supplementation among low calcium intake pregnant womenQ34565461
Maternal vitamin D deficiency increases the risk of preeclampsiaQ34579840
Deficiency in catechol-O-methyltransferase and 2-methoxyoestradiol is associated with pre-eclampsiaQ34656275
1,25-Dihydroxyvitamin D(3) is a negative endocrine regulator of the renin-angiotensin systemQ34793842
Nutrient involvement in preeclampsiaQ35121229
The genetics of pre-eclampsia: a feto-placental or maternal problem?Q35177399
Placental trophoblast-derived factors diminish endothelial barrier functionQ47650864
Characterization of endothelium- dependent relaxation in guinea pig basilar artery - effect of hypoxia and role of cytochrome P450 mono-oxygenase.Q47694967
Endothelial dysfunction in preeclampsiaQ47879591
Decreased endothelium-dependent vascular relaxation during reduction of uterine perfusion pressure in pregnant rat.Q50514586
Systemic hemodynamic and regional blood flow changes in response to chronic reductions in uterine perfusion pressure in pregnant rats.Q50952787
Hypertension produced by reductions in uterine perfusion in the pregnant rat: role of interleukin 6.Q51139503
Hypertension produced by reductions in uterine perfusion in the pregnant rat: role of tumor necrosis factor-alpha.Q51359651
Plasma nitric oxide, endothelin-1, arginase and superoxide dismutase in pre-eclamptic women.Q51436935
Hypocalcemia and pregnancy-induced hypertension produced by low-calcium diet.Q51594970
Alteration of serum soluble endoglin levels after the onset of preeclampsia is more pronounced in women with early-onset.Q51865183
Environmental lead level and pregnancy-induced hypertension.Q51965294
Endothelial function in myometrial resistance arteries of normal pregnant women perfused with syncytiotrophoblast microvillous membranes.Q52055001
Modulation of angiotensin II receptor expression during development and regression of hypoxic pulmonary hypertension.Q52170561
Soluble endoglin and other circulating antiangiogenic factors in preeclampsia.Q53600812
[The role of calcium in the regulation of normal vascular tone and in arterial hypertension]Q53919958
The preliminary characterization of a vasoactive circulating factor(s) in preeclampsia.Q54010076
Maternal plasma vascular endothelial growth factor concentrations in normal and hypertensive pregnancies and their relationship to peripheral vascular resistance.Q54021736
Rho A/Rho kinase: human umbilical artery mRNA expression in normal and pre eclamptic pregnancies and functional role in isoprostane-induced vasoconstriction.Q54594222
Role of endothelin in mediating tumor necrosis factor-induced hypertension in pregnant rats.Q54661322
Essential role of vascular endothelial growth factor in angiotensin II-induced vascular inflammation and remodeling.Q54709411
Soluble fms-like Tyrosine Kinase 1Q56619509
Soluble Flt-1 as a diagnostic marker of pre-eclampsiaQ62504254
Pre-eclampsia and trisomy 13Q67592481
Plasma endothelin levels in preeclampsia: elevation and correlation with uric acid levels and renal impairmentQ68053902
Pre-eclampsia and trisomy 13: a possible associationQ69904752
Protein kinase C in uterine and systemic arteries during ovarian cycle and pregnancyQ70116950
Chronic hypoxia selectively augments endothelium-dependent pulmonary arterial vasodilationQ71465109
Mammal-specific, ERK-dependent, caldesmon phosphorylation in smooth muscle. Quantitation using novel anti-phosphopeptide antibodiesQ73066673
Ca(2+)-insensitive vascular protein kinase C during pregnancy and NOS inhibitionQ73087551
Plasma nitric oxide metabolites and lipid peroxide levels in preeclamptic pregnant women before and after deliveryQ73258662
Selective overexpression of the hypoxia-inducible transcription factor, HIF-2alpha, in placentas from women with preeclampsiaQ73399793
Pregnancy-associated reduction in vascular protein kinase C activity rebounds during inhibition of NO synthesisQ73426782
Stress upregulates arterial matrix metalloproteinase expression and activity via endothelin A receptor activationQ73616010
Phosphorylation of caldesmon by ERK MAP kinases in smooth muscleQ73634448
AT(1) receptor agonistic antibodies from preeclamptic patients cause vascular cells to express tissue factorQ73815485
Matrix metalloproteinase-2 is elevated in the plasma of women with preeclampsiaQ74226798
Increased nitric oxide synthase activity and expression in the human uterine artery during pregnancyQ74253964
Enhanced vascular reactivity during inhibition of nitric oxide synthesis in pregnant ratsQ74518978
Nitric oxide production with preeclampsiaQ74601245
Circulating levels of immunoreactive cytokines in women with preeclampsiaQ77384781
Peripheral blood mononuclear cells stimulate progesterone production by luteal cells derived from pregnant and non-pregnant women: possible involvement of interleukin-4 and interleukin-10 in corpus luteum function and differentiationQ77519168
Tumor necrosis factor-alpha-induced hypertension in pregnant rats results in decreased renal neuronal nitric oxide synthase expressionQ77684136
Endothelin mediates renal vasodilation and hyperfiltration during pregnancy in chronically instrumented conscious ratsQ77755765
Differential expression of renal nitric oxide synthase isoforms during pregnancy in ratsQ77945719
Plasma and 24-h NO(x) and cGMP during normal pregnancy and preeclampsia in women on a reduced NO(x) dietQ78009520
Purification and characterization of a complex from placental syncytiotrophoblast microvillous membranes which inhibits the proliferation of human umbilical vein endothelial cellsQ78018453
Trophoblast deportation and the maternal inflammatory response in pre-eclampsiaQ35190881
Enhanced expression of Ang-(1-7) during pregnancyQ35845564
Atheroprotective effects of antioxidants through inhibition of mitogen-activated protein kinases.Q35859073
Abnormal placentation and the syndrome of preeclampsiaQ35941005
Angiotensin II and vascular inflammation.Q36140047
Preeclampsia: recent insightsQ36288757
Could antioxidant supplementation prevent pre-eclampsia?Q36325124
Fetal programming of hypertensionQ36341270
Brief overview of maternal triglycerides as a risk factor for pre-eclampsia.Q36428553
Calcium supplementation during pregnancy and lactation: effects on the mother and the fetusQ36437354
Neurovascular mechanisms of hypertension in pregnancyQ36486193
Intrauterine growth restriction: fetal programming of hypertension and kidney diseaseQ36569856
Diet during pregnancy and risk of preeclampsia or gestational hypertensionQ36867915
Olmesartan improves endothelin-induced hypertension and oxidative stress in ratsQ36951733
Pathophysiology of hypertension during preeclampsia: linking placental ischemia with endothelial dysfunctionQ37022723
Severe preeclampsia-related changes in gene expression at the maternal-fetal interface include sialic acid-binding immunoglobulin-like lectin-6 and pappalysin-2.Q37072792
Endoglin in angiogenesis and vascular diseasesQ37088038
Inflammatory cytokines in the pathophysiology of hypertension during preeclampsiaQ37119326
Autoantibodies to the angiotensin type I receptor in response to placental ischemia and tumor necrosis factor alpha in pregnant ratsQ37436219
Role of reactive oxygen species in hypertension produced by reduced uterine perfusion in pregnant ratsQ37449704
Transcriptional stimulation of the eNOS gene by the stable prostacyclin analogue beraprost is mediated through cAMP-responsive element in vascular endothelial cells: close link between PGI2 signal and NO pathwaysQ38351435
Phosphotyrosine-dependent targeting of mitogen-activated protein kinase in differentiated contractile vascular cellsQ39371096
Role of angiotensin II and prostaglandin E2 in regulating cardiac fibroblast collagen turnoverQ40380110
Mitochondrial reactive oxygen species and c-Src play a critical role in hypoxic response in vascular smooth muscle cellsQ40418046
Effects of placental proteases on maternal and fetal blood pressure in normal pregnancy and preeclampsiaQ41092408
Mechanisms of smooth muscle contractionQ41169589
Reduced endothelial NO-cGMP vascular relaxation pathway during TNF-alpha-induced hypertension in pregnant ratsQ42515767
Resistance artery smooth muscle function in pregnancy and preeclampsiaQ42516324
Nitric oxide synthase activity in placentae from women with pre-eclampsiaQ42520050
Endothelin-1 induces an angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo.Q42757110
Stabilization of hypoxia-inducible factor-1{alpha} by prostacyclin under prolonged hypoxia via reducing reactive oxygen species level in endothelial cells.Q43413808
Association of maternal endothelial dysfunction with preeclampsiaQ43553727
Reduced uterine perfusion pressure during pregnancy in the rat is associated with increases in arterial pressure and changes in renal nitric oxide.Q43576536
Regulation of prostacyclin synthesis by angiotensin II and TNF-alpha in vascular smooth muscleQ43577316
Elevated levels of S-nitrosoalbumin in preeclampsia plasmaQ43633772
High intake of energy, sucrose, and polyunsaturated fatty acids is associated with increased risk of preeclampsiaQ43717221
The role of endothelium-derived hyperpolarizing factor in the regulation of the uterine circulation in pregnant ratsQ43745798
Important role of Rho-kinase in the pathogenesis of cardiovascular inflammation and remodeling induced by long-term blockade of nitric oxide synthesis in ratsQ43888051
Differential mechanisms of endothelium-dependent vasodilator responses in human myometrial small arteries in normal pregnancy and pre-eclampsiaQ44048792
Enhanced thromboxane synthesis during chronic reductions in uterine perfusion pressure in pregnant ratsQ44130345
Enhanced [Ca2+]i in renal arterial smooth muscle cells of pregnant rats with reduced uterine perfusion pressureQ44185600
Reduced function of endothelial prostacyclin in human omental resistance arteries in pre-eclampsiaQ44218040
Pulmonary vascular endothelial growth factor and nitric oxide interaction during total cardiopulmonary bypass in neonatal pigsQ44456864
Tumor necrosis factor alpha in the bovine oviduct during the estrous cycle: messenger RNA expression and effect on secretion of prostaglandins, endothelin-1, and angiotensin II.Q44475138
Pre-eclampsia (EPH-gestosis)-induced decrease of MMP-s content in the umbilical cord arteryQ44555376
Reduced endothelial NO-cGMP-mediated vascular relaxation and hypertension in IL-6-infused pregnant ratsQ44715072
Placental lipid peroxides and thromboxane are increased and prostacyclin is decreased in women with preeclampsiaQ44897228
The imbalance between thromboxane and prostacyclin in preeclampsia is associated with an imbalance between lipid peroxides and vitamin E in maternal bloodQ44929427
Inhibition of inducible nitric oxide synthase and superoxide production reduces matrix metalloproteinase-9 activity and restores coronary vasomotor function in rat cardiac allograftsQ45008785
Activation of Rho/Rho kinase signaling pathway by reactive oxygen species in rat aortaQ45061635
Changes in endothelium-derived hyperpolarizing factor in hypertension and ageing: response to chronic treatment with renin-angiotensin system inhibitorsQ45102837
Matrix metalloproteinase-specific inhibition of Ca2+ entry mechanisms of vascular contractionQ45159052
Effects of vasoactive agents on intracellular calcium and force in myometrial and subcutaneous resistance arteries isolated from preeclamptic, pregnant, and nonpregnant womanQ45254319
Investigation of vascular responses in endothelial nitric oxide synthase/cyclooxygenase-1 double-knockout mice: key role for endothelium-derived hyperpolarizing factor in the regulation of blood pressure in vivo.Q45256231
Preeclampsia, gestational hypertension and intrauterine growth restriction, related or independent conditions?Q46342132
Angiogenin and vascular endothelial growth factor in pregnancies complicated by preeclampsiaQ46440312
Increased phospholipase A2 and thromboxane but not prostacyclin production by placental trophoblast cells from normal and preeclamptic pregnancies cultured under hypoxia conditionQ46454719
Vasoactivity to and endogenous release of vascular endothelial growth factor in the in vitro perfused human placental lobule from pregnancies complicated by preeclampsia.Q46475774
Angiotensin-converting enzyme inhibitors reveal non-NO-, non-prostacycline-mediated endothelium-dependent relaxation in internal thoracic artery of hypertensive patientsQ46590537
Mechanisms of endothelin-1-induced contraction in pulmonary arteries from chronically hypoxic ratsQ46697023
Evidence that inward rectifier K+ channels mediate relaxation by the PGI2 receptor agonist cicaprost via a cyclic AMP-independent mechanismQ46719781
Angiotensin II infusion alters vascular function in mouse resistance vessels: roles of O and endotheliumQ46844588
Women with preeclampsia have higher plasma endothelin levels than women with normal pregnanciesQ46878600
Endothelium-derived hyperpolarizing factor in preeclampsia: heterogeneous contribution, mechanisms, and morphological prerequisitesQ46886600
The positive inotropic effect of angiotensin II: role of endothelin-1 and reactive oxygen speciesQ46966458
Plasma- and urine concentrations of nitrite/nitrate and cyclic Guanosinemonophosphate in intrauterine growth restricted and preeclamptic pregnanciesQ46987465
Genetic and environmental factors associated with the development of hypertension in pregnancyQ47605160
P433issue1
P304page(s)60-75
P577publication date2010-03-01
P1433published inCurrent Bioactive CompoundsQ15765834
P1476titleCirculating and Vascular Bioactive Factors during Hypertension in Pregnancy
P478volume6

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cites work (P2860)
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Q93074775Intrauterine Growth Restriction and Hyperoxia as a Cause of White Matter Injury
Q46342648Matrix Metalloproteinases in Normal Pregnancy and Preeclampsia
Q37136212Mechanisms of Endothelial Dysfunction in Hypertensive Pregnancy and Preeclampsia
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Q34205668Pregnancy disorders appear to modify the risk for retinopathy of prematurity associated with neonatal hyperoxemia and bacteremia
Q26828020Role of endothelin in uteroplacental circulation and fetal vascular function

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