Pathogenesis of pre-eclampsia: marinobufagenin and angiogenic imbalance as biomarkers of the syndrome

scientific article published on 02 February 2012

Pathogenesis of pre-eclampsia: marinobufagenin and angiogenic imbalance as biomarkers of the syndrome is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.TRSL.2012.01.005
P8608Fatcat IDrelease_gb5osaohwbcg7drjsf4mabf3eu
P698PubMed publication ID22683369
P5875ResearchGate publication ID225286413

P50authorDavid C ZawiejaQ47419069
P2093author name stringMohammad N Uddin
Thomas J Kuehl
Richard O Jones
Steven R Allen
P2860cites workThe placental problem: linking abnormal cytotrophoblast differentiation to the maternal symptoms of preeclampsiaQ24795491
Endogenous and exogenous cardiac glycosides: their roles in hypertension, salt metabolism, and cell growthQ36817975
Monoclonal antibody to an endogenous bufadienolide, marinobufagenin, reverses preeclampsia-induced Na/K-ATPase inhibition and lowers blood pressure in NaCl-sensitive hypertensionQ36974139
Inflammatory cytokines in the pathophysiology of hypertension during preeclampsiaQ37119326
AT1-receptor autoantibodies and uteroplacental RAS in pregnancy and pre-eclampsiaQ37132801
Marinobufagenin causes endothelial cell monolayer hyperpermeability by altering apoptotic signalingQ37217986
Oxidative stress contributes to soluble fms-like tyrosine kinase-1 induced vascular dysfunction in pregnant ratsQ37449693
Role of reactive oxygen species in hypertension produced by reduced uterine perfusion in pregnant ratsQ37449704
Neurologic complications of pre-eclampsiaQ37493270
Emerging role of the bufadienolides in cardiovascular and kidney diseasesQ37736752
The concept of the natriuretic hormone and its relation to hypertension.Q39824388
Examination of the cellular mechanisms by which marinobufagenin inhibits cytotrophoblast functionQ39988758
Marinobufagenin inhibits proliferation and migration of cytotrophoblast and CHO cellsQ40012513
The role of excessive volume expansion in the pathogenesis of preeclampsiaQ40310697
Marinobufagenin impairs first trimester cytotrophoblast differentiationQ40320679
Preeclampsia: an excessive maternal inflammatory response to pregnancyQ40824430
Pregnancy-related mortality in the United States, 1987-1990.Q41022994
Preeclampsia: an endothelial cell disorderQ41281924
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Vascular endothelial growth factor induced functional and morphologic signs of endothelial dysfunction in isolated arteries from normal pregnant womenQ42436216
Contribution of angiogenic factors in a rat model of pre-eclampsiaQ42933447
Marinobufagenin, resibufogenin and preeclampsiaQ43157537
Alterations in the renin-angiotensin system in a rat model of human preeclampsiaQ43218182
The treatment of preeclampsia in a rat model employing DigibindQ43262762
Maternal autoantibodies from preeclamptic patients activate angiotensin receptors on human trophoblast cellsQ44320558
AT1 receptor agonistic antibodies from preeclamptic patients stimulate NADPH oxidaseQ44385661
Genetic variation in solute carrier genes is associated with preeclampsia.Q44474766
Antibodies from preeclamptic patients stimulate increased intracellular Ca2+ mobilization through angiotensin receptor activationQ45069619
Gadd45a stress signaling regulates sFlt-1 expression in preeclampsia.Q46006231
A rat model of preeclampsiaQ46342948
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Shear stress activates p60src-Ras-MAPK signaling pathways in vascular endothelial cellsQ46668484
Involvement of marinobufagenin in a rat model of human preeclampsiaQ46716993
Effects of an endogenous ouabainlike compound on heart and aortaQ46844124
Pregnancy prevents hypertensive remodeling of cerebral arteries: a potential role in the development of eclampsiaQ46870281
Neurological complications associated with the pre-eclampsia/eclampsia syndromeQ46890619
Resibufogenin corrects hypertension in a rat model of human preeclampsiaQ46919214
Circulating angiogenic factors and the risk of preeclampsiaQ47217679
Simultaneous measurement of marinobufagenin, ouabain, and hypertension-associated protein in various disease statesQ47771935
Endogenous marinobufagenin-like factor in acute plasma volume expansionQ47771986
Extracellular fluid volumes in pregnancy-induced hypertensionQ50798261
Marinobufagenin is an upstream modulator of Gadd45a stress signaling in preeclampsiaQ53300122
Soluble endoglin and other circulating antiangiogenic factors in preeclampsia.Q53600812
Maternal plasma levels of vascular endothelial growth factor in normotensive pregnancies and in pregnancies complicated by pre-eclampsia.Q54230092
Circulating bufodienolide and cardenolide sodium pump inhibitors in preeclampsia.Q54426625
The upregulation of angiotensin II receptor AT1 in human preeclamptic placentaQ58029863
A circulating inhibitor of (Na+ + K+) ATPase associated with essential hypertensionQ59079199
Elevated serum levels of vascular endothelial growth factor in patients with preeclampsiaQ59367832
Plasma marinobufagenin-like and ouabain-like immunoreactivity during saline volume expansion in anesthetized dogsQ62633259
Changes in the renin-angiotensin system in primigravidae with hypertensive disease of pregnancyQ67321033
Measurement of individual plasma angiotensins in normal pregnancy and pregnancy-induced hypertensionQ67947877
Renin-aldosterone relationships in pregnancy-induced hypertensionQ68044331
Increased fetoplacental active renin production in pregnancy-induced hypertensionQ68178270
Analysis of changes in the renin-angiotensin system during pregnancyQ68640705
Hormone production during pregnancy in the primigravid patient. II. Plasma levels of deoxycorticosterone throughout pregnancy of normal women and women who developed pregnancy-induced hypertensionQ71386510
Trophoblastic invasion of human decidua from 8 to 18 weeks of pregnancyQ71413387
Elevated endoxin-like factor complicating a multifetal second trimester pregnancy: treatment with digoxin-binding immunoglobulinQ71861419
Pre-eclampsia is associated with an excess of proliferative immature intermediate trophoblastQ72297496
Chronic blood pressure effects of bufalin, a sodium-potassium ATPase inhibitor, in ratsQ72710474
Alpha 1-adrenergic receptor antibodies in patients with primary hypertensionQ73089177
Preeclampsia-eclampsia: clinical and neuroradiographic correlates and insights into the pathogenesis of hypertensive encephalopathyQ73141222
Suppression of serum vascular endothelial growth factor immunoreactivity in normal pregnancy and in pre-eclampsiaQ73154748
Reductions of vascular endothelial growth factor and placental growth factor concentrations in severe preeclampsiaQ73305965
AT(1) receptor agonistic antibodies from preeclamptic patients cause vascular cells to express tissue factorQ73815485
Definitive molecular evidence of renin-angiotensin system in human uterine decidual cellsQ74188076
Preeclampsia -- searching for the causeQ75425657
Human spiral artery renin-angiotensin systemQ77418886
Endothelial junctional protein redistribution and increased monolayer permeability in human umbilical vein endothelial cells isolated during preeclampsiaQ77660104
Effects of two putative endogenous digitalis-like factors, marinobufagenin and ouabain, on the Na+, K+-pump in human mesenteric arteriesQ77788611
The localization and expression of the renin-angiotensin system in the human placenta throughout pregnancyQ78039553
The renal excretion of sodium in women with preeclampsiaQ78321878
Pressor response to angiotonin in pregnant and nonpregnant womenQ78762451
Angiogenic factors and preeclampsiaQ79382870
Apoptotic signaling induces hyperpermeability following hemorrhagic shockQ79793823
[Edema in pregnancy--trivial?]Q81160035
Hypertension produced by reduced uterine perfusion in pregnant rats is associated with increased soluble fms-like tyrosine kinase-1 expressionQ81411178
Resibufogenin administration prevents oxidative stress in a rat model of human preeclampsiaQ82975843
Hypertension in response to AT1-AA: role of reactive oxygen species in pregnancy-induced hypertensionQ83799951
Is inflammation the cause of pre-eclampsia?Q27007059
Implantation and the survival of early pregnancyQ28215729
Soluble endoglin contributes to the pathogenesis of preeclampsiaQ28244053
Cerebrovascular function in pregnancy and eclampsiaQ28305037
Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsiaQ29615916
Blood-brain barrier, brain metabolism and cerebral blood flowQ30752573
Marinobufagenin, an endogenous alpha-1 sodium pump ligand, in hypertensive Dahl salt-sensitive ratsQ32071317
Cerebral blood flow autoregulation and edema formation during pregnancy in anesthetized rats.Q33268023
Preeclampsia: the endothelium, circulating factor(s) and vascular endothelial growth factorQ33538256
Vascular leak in a rat model of preeclampsiaQ33651001
Patients with preeclampsia develop agonistic autoantibodies against the angiotensin AT1 receptorQ33848380
Current topic: the uteroplacental renin-angiotensin systemQ34001273
Sodium ions, calcium ions, blood pressure regulation, and hypertension: a reassessment and a hypothesisQ34170867
A study of angiotensin II pressor response throughout primigravid pregnancyQ34512573
Endogenous cardiotonic steroids: physiology, pharmacology, and novel therapeutic targetsQ34605877
Endogenous cardiac glycosides, a new class of steroid hormonesQ34655320
Pregnancy and the risk of strokeQ34683028
Pre-eclampsia: more than pregnancy-induced hypertensionQ34726951
Role of angiotensin II type I receptor agonistic autoantibodies (AT1-AA) in preeclampsiaQ34785813
Preeclampsia. Part 1: clinical and pathophysiologic considerationsQ34827918
Preeclampsia. Part 2: experimental and genetic considerationsQ34827936
Role of Reactive Oxygen Species During Hypertension in Response to Chronic Antiangiogenic Factor (sFlt-1) Excess in Pregnant RatsQ35086662
Trophoblastic remodeling in normal and preeclamptic pregnancies: implication of cytokines.Q35172646
PLASMA VOLUME, TOTAL CIRCULATING PROTEIN, AND "AVAILABLE FLUID" ABNORMALITIES IN PREECLAMPSIA AND ECLAMPSIA.Q35389030
IL-6-induced pathophysiology during pre-eclampsia: potential therapeutic role for magnesium sulfate?Q35581520
Potential roles of angiotensin receptor-activating autoantibody in the pathophysiology of preeclampsiaQ35681821
Angiotensin II induces soluble fms-Like tyrosine kinase-1 release via calcineurin signaling pathway in pregnancyQ35699115
Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant miceQ35701236
Renin angiotensin signaling in normal pregnancy and preeclampsiaQ35743816
Trophoblast differentiation during embryo implantation and formation of the maternal-fetal interfaceQ35889634
Role of the renin-angiotensin system in the pathogenesis of preeclampsiaQ36064478
Endogenous cardiac glycosides: hormones using the sodium pump as signal transducerQ36247906
Signaling via beta(2) integrins triggers neutrophil-dependent alteration in endothelial barrier function.Q36404687
P433issue2
P921main subjectpathogenesisQ372016
biomarkerQ864574
pre-eclampsiaQ61335
P304page(s)99-113
P577publication date2012-02-02
P1433published inTranslational ResearchQ15761127
P1476titlePathogenesis of pre-eclampsia: marinobufagenin and angiogenic imbalance as biomarkers of the syndrome
P478volume160

Reverse relations

cites work (P2860)
Q33963982A synthetic thiourea-based tripodal receptor that impairs the function of human first trimester cytotrophoblast cells
Q37000033Apoptotic and stress signaling markers are augmented in preeclamptic placenta and umbilical cord
Q35383992Endogenous digitalis-like factors: an overview of the history
Q37612429Evidence of an imbalance of angiogenic/antiangiogenic factors in massive perivillous fibrin deposition (maternal floor infarction): a placental lesion associated with recurrent miscarriage and fetal death
Q38888539Hyperglycemia down-regulates cGMP-dependent protein kinase I expression in first trimester cytotrophoblast cells.
Q49917325Long Non-Coding RNAs Serve as Diagnostic Biomarkers of Preeclampsia and Modulate Migration and Invasiveness of Trophoblast Cells.
Q52723876Marinobufagenin inhibits glioma growth through sodium pump α1 subunit and ERK signaling-mediated mitochondrial apoptotic pathway.
Q33430391Neonatal Thrombocytopenia as a Consequence of Maternal Preeclampsia
Q37199922Pathogenesis and promising non-invasive markers for preeclampsia
Q33419126Pre-eclampsia has an adverse impact on maternal and fetal health
Q33748770Synthetic Receptors Induce Anti Angiogenic and Stress Signaling on Human First Trimester Cytotrophoblast Cells

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