The de novo cytosine methyltransferase DRM2 requires intact UBA domains and a catalytically mutated paralog DRM3 during RNA-directed DNA methylation in Arabidopsis thaliana.

scientific article

The de novo cytosine methyltransferase DRM2 requires intact UBA domains and a catalytically mutated paralog DRM3 during RNA-directed DNA methylation in Arabidopsis thaliana. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PGEN.1001182
P932PMC publication ID2965745
P698PubMed publication ID21060858
P5875ResearchGate publication ID47718793

P50authorIan HendersonQ42756124
Angelique DelerisQ82318323
P2093author name stringSteven E Jacobsen
Xuehua Zhong
William Wong
Krystyna A Kelly
Sriharsa Pradhan
Hang Gyeong Chin
Gregory A Horwitz
P2860cites workDNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian developmentQ22010765
EUKARYOTIC CYTOSINE METHYLTRANSFERASESQ22255656
Regulation of myotubularin-related (MTMR)2 phosphatidylinositol phosphatase by MTMR5, a catalytically inactive phosphataseQ24299014
Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylationQ24338119
Locus-specific control of asymmetric and CpNpG methylation by the DRM and CMT3 methyltransferase genesQ24540245
Establishing, maintaining and modifying DNA methylation patterns in plants and animalsQ24630397
DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNAQ24645346
Origins and evolution of eukaryotic RNA interferenceQ24647077
Genetic and functional diversification of small RNA pathways in plantsQ24797901
Solution structures of UBA domains reveal a conserved hydrophobic surface for protein-protein interactionsQ27639223
Structural basis of ubiquitin recognition by the ubiquitin-associated (UBA) domain of the ubiquitin ligase EDDQ27648554
Reconstitution and mechanism of the stimulation of de novo methylation by human DNMT3LQ28250975
RNAi, DRD1, and histone methylation actively target developmentally important non-CG DNA methylation in arabidopsisQ28469008
MIWI2 is essential for spermatogenesis and repression of transposons in the mouse male germlineQ28507423
Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprintingQ28508038
A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in miceQ28511242
DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testesQ28513286
Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3LQ28585211
Mili, a mammalian member of piwi family gene, is essential for spermatogenesisQ28585613
miwi, a murine homolog of piwi, encodes a cytoplasmic protein essential for spermatogenesisQ28589737
Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA methylation patterningQ29615977
Highly integrated single-base resolution maps of the epigenome in ArabidopsisQ29616098
Role of transposable elements in heterochromatin and epigenetic controlQ29616253
Dynamic regulation of ARGONAUTE4 within multiple nuclear bodies in Arabidopsis thalianaQ33319282
A structural-maintenance-of-chromosomes hinge domain-containing protein is required for RNA-directed DNA methylation.Q33345476
Three SRA-domain methylcytosine-binding proteins cooperate to maintain global CpG methylation and epigenetic silencing in Arabidopsis.Q33360264
SRA-domain proteins required for DRM2-mediated de novo DNA methylationQ33388216
Mobilization of transposons by a mutation abolishing full DNA methylation in ArabidopsisQ33946286
RNA polymerase IV directs silencing of endogenous DNA.Q33984841
Genome-wide high-resolution mapping and functional analysis of DNA methylation in arabidopsisQ34562910
The DNA methylation locus DDM1 is required for maintenance of gene silencing in ArabidopsisQ35201604
Conserved plant genes with similarity to mammalian de novo DNA methyltransferases.Q35702821
Allosteric regulation of an essential trypanosome polyamine biosynthetic enzyme by a catalytically dead homologQ35850113
Heritable epigenetic mutation of a transposon-flanked Arabidopsis gene due to lack of the chromatin-remodeling factor DDM1.Q35941544
Reiterated WG/GW motifs form functionally and evolutionarily conserved ARGONAUTE-binding platforms in RNAi-related components.Q36023554
PolV(PolIVb) function in RNA-directed DNA methylation requires the conserved active site and an additional plant-specific subunitQ37070626
NRPD4, a protein related to the RPB4 subunit of RNA polymerase II, is a component of RNA polymerases IV and V and is required for RNA-directed DNA methylationQ37111127
An effector of RNA-directed DNA methylation in arabidopsis is an ARGONAUTE 4- and RNA-binding protein.Q37238540
RNA-directed DNA methylation requires an AGO4-interacting member of the SPT5 elongation factor family.Q37264800
Small RNA guides for de novo DNA methylation in mammalian germ cellsQ37319897
Small RNA silencing pathways in germ and stem cellsQ37408998
A conserved transcriptional regulator is required for RNA-directed DNA methylation and plant developmentQ37457953
Involvement of putative SNF2 chromatin remodeling protein DRD1 in RNA-directed DNA methylationQ38341855
Tandem repeats upstream of the Arabidopsis endogene SDC recruit non-CG DNA methylation and initiate siRNA spreading.Q39161375
IDN1 and IDN2 are required for de novo DNA methylation in Arabidopsis thalianaQ39733178
DNA methyltransferasesQ40626444
Reinforcement of silencing at transposons and highly repeated sequences requires the concerted action of two distinct RNA polymerases IV in Arabidopsis.Q41807998
Role of CG and non-CG methylation in immobilization of transposons in ArabidopsisQ44348859
RNA silencing genes control de novo DNA methylationQ44664989
Role of the DRM and CMT3 methyltransferases in RNA-directed DNA methylation.Q44696942
DNA methylation profiling identifies CG methylation clusters in Arabidopsis genesQ45236570
Bursts of retrotransposition reproduced in ArabidopsisQ45347155
An ARGONAUTE4-containing nuclear processing center colocalized with Cajal bodies in Arabidopsis thaliana.Q46026182
Role of Arabidopsis ARGONAUTE4 in RNA-directed DNA methylation triggered by inverted repeats.Q46034234
Role of the arabidopsis DRM methyltransferases in de novo DNA methylation and gene silencingQ46125181
Dissecting Arabidopsis thaliana DICER function in small RNA processing, gene silencing and DNA methylation patterningQ46185049
DNA methylation is independent of RNA interference in NeurosporaQ47289161
The late flowering phenotype of fwa mutants is caused by gain-of-function epigenetic alleles of a homeodomain geneQ47812243
Atypical RNA polymerase subunits required for RNA-directed DNA methylationQ48136173
Plant nuclear RNA polymerase IV mediates siRNA and DNA methylation-dependent heterochromatin formationQ48146967
Dnmt3L and the establishment of maternal genomic imprintsQ48874297
Mechanism of stimulation of catalytic activity of Dnmt3A and Dnmt3B DNA-(cytosine-C5)-methyltransferases by Dnmt3L.Q51549058
Selective epigenetic control of retrotransposition in Arabidopsis.Q51926767
Partially redundant functions of Arabidopsis DICER-like enzymes and a role for DCL4 in producing trans-acting siRNAs.Q52043494
Genome-wide analysis of Arabidopsis thaliana DNA methylation uncovers an interdependence between methylation and transcription.Q53013759
An atypical RNA polymerase involved in RNA silencing shares small subunits with RNA polymerase II.Q54781004
An SNF2 protein associated with nuclear RNA silencing and the spread of a silencing signal between cells in ArabidopsisQ56926925
Stimulation effect of Dnmt3L on the DNA methylation activity of Dnmt3a2Q80198565
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue10
P921main subjectArabidopsis thalianaQ158695
cytosineQ178425
DNA methylationQ874745
P304page(s)e1001182
P577publication date2010-10-28
P1433published inPLOS GeneticsQ1893441
P1476titleThe de novo cytosine methyltransferase DRM2 requires intact UBA domains and a catalytically mutated paralog DRM3 during RNA-directed DNA methylation in Arabidopsis thaliana
P478volume6

Reverse relations

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