scholarly article | Q13442814 |
P2093 | author name string | Andrew E Aplin | |
Ethan V Abel | |||
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Mutations of the BRAF gene in human cancer | Q27860760 | ||
A new mathematical model for relative quantification in real-time RT-PCR | Q27860781 | ||
WAF1, a potential mediator of p53 tumor suppression | Q27861121 | ||
The emerging roles of forkhead box (Fox) proteins in cancer | Q28253741 | ||
Mutant B-RAF signaling and cyclin D1 regulate Cks1/S-phase kinase-associated protein 2-mediated degradation of p27Kip1 in human melanoma cells | Q28259285 | ||
Requirement for Foxd3 in maintaining pluripotent cells of the early mouse embryo | Q28506803 | ||
Genesis, a winged helix transcriptional repressor with expression restricted to embryonic stem cells | Q28591060 | ||
Foxd3 is required in the trophoblast progenitor cell lineage of the mouse embryo | Q28592381 | ||
BRAF mutation predicts sensitivity to MEK inhibition | Q29614281 | ||
Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma | Q29614282 | ||
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Oncogenic BRAF regulates melanoma proliferation through the lineage specific factor MITF. | Q33352015 | ||
The winged-helix transcription factor FoxD3 is important for establishing the neural crest lineage and repressing melanogenesis in avian embryos. | Q33939222 | ||
Cyclin D3 expression in melanoma cells is regulated by adhesion-dependent phosphatidylinositol 3-kinase signaling and contributes to G1-S progression | Q34703578 | ||
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ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation | Q36647913 | ||
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Regulation of embryonic stem cell self-renewal and pluripotency by Foxd3 | Q39957518 | ||
AZD6244 (ARRY-142886), a potent inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1/2 kinases: mechanism of action in vivo, pharmacokinetic/pharmacodynamic relationship, and potential for combination in precl | Q40093939 | ||
B-RAF and PI-3 kinase signaling protect melanoma cells from anoikis | Q40302263 | ||
Stimulation of oncogenic metabotropic glutamate receptor 1 in melanoma cells activates ERK1/2 via PKCepsilon | Q40348200 | ||
The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts | Q40967344 | ||
Mutational analysis of the human p53 gene in malignant melanoma | Q41697274 | ||
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Dissection of the functional interaction between p53 and the embryonic proto-oncoprotein PAX3. | Q42819906 | ||
SnapShot: p53 posttranslational modifications | Q43118019 | ||
FOXD3 regulates the lineage switch between neural crest-derived glial cells and pigment cells by repressing MITF through a non-canonical mechanism | Q43130524 | ||
Requirement for Foxd3 in the maintenance of neural crest progenitors | Q43139378 | ||
High prevalence of BRAF mutations in thyroid cancer: genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma | Q44387406 | ||
Raf/MEK/MAPK signaling stimulates the nuclear translocation and transactivating activity of FOXM1c | Q45238610 | ||
Effectively targeting BRAF in melanoma: a formidable challenge | Q46424236 | ||
Mutant B-RAF mediates resistance to anoikis via Bad and Bim. | Q46774780 | ||
An organometallic protein kinase inhibitor pharmacologically activates p53 and induces apoptosis in human melanoma cells | Q47583291 | ||
A negative feedback loop of transcription factors that controls stem cell pluripotency and self-renewal | Q56067490 | ||
Adhesion control of cyclin D1 and p27Kip1 levels is deregulated in melanoma cells through BRAF-MEK-ERK signaling | Q58450931 | ||
Constitutive mitogen-activated protein kinase activation in melanoma is mediated by both BRAF mutations and autocrine growth factor stimulation | Q73013877 | ||
Suppression of BRAF(V599E) in human melanoma abrogates transformation | Q79074168 | ||
Clonally cultured differentiated pigment cells can dedifferentiate and generate multipotent progenitors with self-renewing potential | Q79277701 | ||
P433 | issue | 7 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 2891-2900 | |
P577 | publication date | 2010-03-23 | |
P1433 | published in | Cancer Research | Q326097 |
P1476 | title | FOXD3 is a mutant B-RAF-regulated inhibitor of G(1)-S progression in melanoma cells | |
P478 | volume | 70 |
Q92642778 | Adaptive Responses as Mechanisms of Resistance to BRAF Inhibitors in Melanoma |
Q35683271 | Adaptive upregulation of FOXD3 and resistance to PLX4032/4720-induced cell death in mutant B-RAF melanoma cells |
Q58606024 | BRAF Splice Variant Resistance to RAF Inhibitor Requires Enhanced MEK Association |
Q41056167 | BRAF mutation-specific promoter methylation of FOX genes in colorectal cancer |
Q38757522 | Crosstalk signaling in targeted melanoma therapy |
Q34742221 | CtBP2 downregulation during neural crest specification induces expression of Mitf and REST, resulting in melanocyte differentiation and sympathoadrenal lineage suppression |
Q38708426 | Curcumin inhibits prostate cancer by targeting PGK1 in the FOXD3/miR-143 axis |
Q35642026 | Decreased FOXD3 Expression Is Associated with Poor Prognosis in Patients with High-Grade Gliomas |
Q37393397 | Down-regulation of long non-coding RNA FOXD3 antisense RNA 1 (FOXD3-AS1) inhibits cell proliferation, migration, and invasion in malignant glioma cells |
Q37587383 | Downregulation of the transcription factor, FoxD3, is associated with lymph node metastases in invasive ductal carcinomas of the breast |
Q36660155 | Dynamic DNA methylation across diverse human cell lines and tissues |
Q47203970 | ERK-mediated phosphorylation regulates SOX10 sumoylation and targets expression in mutant BRAF melanoma. |
Q34389137 | Effects and interactions of MiR-577 and TSGA10 in regulating esophageal squamous cell carcinoma |
Q92642727 | Enhanced JunD/RSK3 signalling due to loss of BRD4/FOXD3/miR-548d-3p axis determines BET inhibition resistance |
Q36468749 | Establishment and Characterization of Orthotopic Mouse Models for Human Uveal Melanoma Hepatic Colonization |
Q36951681 | FOXD3 Promotes PAX3 Expression in Melanoma Cells |
Q38603133 | FOXD3 Regulates CSC Marker, DCLK1-S, and Invasive Potential: Prognostic Implications in Colon Cancer |
Q92659648 | FOXD3 Regulates VISTA Expression in Melanoma |
Q37420182 | FOXD3 is a novel tumor suppressor that affects growth, invasion, metastasis and angiogenesis of neuroblastoma |
Q37706298 | FOXD3 is a tumor suppressor of colon cancer by inhibiting EGFR-Ras-Raf-MEK-ERK signal pathway |
Q42546275 | FOXD3 modulates migration through direct transcriptional repression of TWIST1 in melanoma |
Q33779603 | FOXD3 regulates anaplastic thyroid cancer progression |
Q24633339 | FOXD3 regulates migration properties and Rnd3 expression in melanoma cells |
Q37881690 | Finding the root of the problem: the quest to identify melanoma stem cells |
Q39084764 | Foxd3 suppresses interleukin-10 expression in B cells |
Q43215055 | Future perspectives in melanoma research. Meeting report from the "Melanoma research: a bridge from Naples to the World. Napoli, December 5th-6th 2011". |
Q36341898 | GSK3β inhibition blocks melanoma cell/host interactions by downregulating N-cadherin expression and decreasing FAK phosphorylation |
Q37323162 | Genetic variation in phosphodiesterase (PDE) 7B in chronic lymphocytic leukemia: overview of genetic variants of cyclic nucleotide PDEs in human disease |
Q93270780 | Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility |
Q26783032 | Histone Modifications, Modifiers and Readers in Melanoma Resistance to Targeted and Immune Therapy |
Q41641032 | Hypermethylation of FOXD3 suppresses cell proliferation, invasion and metastasis in hepatocellular carcinoma |
Q37365693 | In vivo MAPK reporting reveals the heterogeneity in tumoral selection of resistance to RAF inhibitors |
Q37233445 | JUN dependency in distinct early and late BRAF inhibition adaptation states of melanoma |
Q36682132 | MIG6 Is MEK Regulated and Affects EGF-Induced Migration in Mutant NRAS Melanoma. |
Q41821510 | MITF depletion elevates expression levels of ERBB3 receptor and its cognate ligand NRG1-beta in melanoma |
Q36793441 | Melanoma adapts to RAF/MEK inhibitors through FOXD3-mediated upregulation of ERBB3 |
Q38460190 | Mining for novel tumor suppressor genes using a shortest path approach |
Q34786402 | Overcoming resistance to BRAF inhibition in BRAF-mutated metastatic melanoma |
Q36065213 | PAX3 and FOXD3 Promote CXCR4 Expression in Melanoma |
Q91814939 | Protein Kinase A Signaling Inhibits Iridophore Differentiation in Zebrafish |
Q36362336 | RAC1 P29S regulates PD-L1 expression in melanoma. |
Q37625751 | Resistance to RAF inhibitors revisited |
Q38041728 | Resistance to chemotherapy: short-term drug tolerance and stem cell-like subpopulations. |
Q36451902 | SHOC2 and CRAF mediate ERK1/2 reactivation in mutant NRAS-mediated resistance to RAF inhibitor |
Q49733370 | Screening of FOXD3 targets in lung cancer via bioinformatics analysis |
Q36961746 | Selective RAF inhibitor impairs ERK1/2 phosphorylation and growth in mutant NRAS, vemurafenib‐resistant melanoma cells |
Q61453545 | Serum Fork-Head Box D3 (FOXD3) Expression Is Down-Regulated in and Associated with Diagnosis of Patients with Non-Small Cell Lung Cancer |
Q52721955 | Systems biology analysis of mitogen activated protein kinase inhibitor resistance in malignant melanoma. |
Q38741265 | Tanapoxvirus lacking a neuregulin-like gene regresses human melanoma tumors in nude mice |
Q27853026 | Targeting TBK1 inhibits migration and resistance to MEK inhibitors in mutant NRAS melanoma |
Q34104135 | The MAPK pathway as an apoptosis enhancer in melanoma |
Q93235559 | The lncRNA RMEL3 protects immortalized cells from serum withdrawal-induced growth arrest and promotes melanoma cell proliferation and tumor growth |
Q48090844 | Transcription factors as critical players in melanoma invasiveness, drug resistance, and opportunities for therapeutic drug development. |
Q52949999 | Tumor suppression function of FoxD3 in lung cancer |
Q44447711 | microRNA regulation of skin pigmentation in fish |
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