Modeling the zebrafish segmentation clock's gene regulatory network constrained by expression data suggests evolutionary transitions between oscillating and nonoscillating transcription

scientific article

Modeling the zebrafish segmentation clock's gene regulatory network constrained by expression data suggests evolutionary transitions between oscillating and nonoscillating transcription is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1534/GENETICS.114.163642
P932PMC publication ID4063927
P698PubMed publication ID24663100
P5875ResearchGate publication ID261068152

P2093author name stringScott A Holley
Yuan Kang
Jamie Schwendinger-Schreck
P2860cites workUniversally sloppy parameter sensitivities in systems biology modelsQ21145658
Somitogenesis clock-wave initiation requires differential decay and multiple binding sites for clock proteinQ27335009
Repressor dimerization in the zebrafish somitogenesis clockQ27339483
A spatio-temporal model of Notch signalling in the zebrafish segmentation clock: conditions for synchronised oscillatory dynamicsQ27355549
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Topology and dynamics of the zebrafish segmentation clock core circuitQ28481517
Instability of Hes7 protein is crucial for the somite segmentation clockQ28505422
Periodic repression by the bHLH factor Hes7 is an essential mechanism for the somite segmentation clockQ28585491
Dynamic expression and essential functions of Hes7 in somite segmentationQ28593057
Master transcription factors and mediator establish super-enhancers at key cell identity genesQ29618062
Control of the segmentation process by graded MAPK/ERK activation in the chick embryoQ30476074
Single-cell-resolution imaging of the impact of Notch signaling and mitosis on segmentation clock dynamicsQ30528453
fgf8 mRNA decay establishes a gradient that couples axial elongation to patterning in the vertebrate embryo.Q54731950
A β-catenin gradient links the clock and wavefront systems in mouse embryo segmentationQ60492559
A clock and wavefront model for control of the number of repeated structures during animal morphogenesisQ60698414
Setting the tempo in development: an investigation of the zebrafish somite clock mechanismQ33286066
Zebrafish whole mount high-resolution double fluorescent in situ hybridizationQ33422268
Inferring genetic interactions via a nonlinear model and an optimization algorithmQ33534524
Zebrafish hairy/enhancer of split protein links FGF signaling to cyclic gene expression in the periodic segmentation of somites.Q33826911
Expression of the oscillating gene her1 is directly regulated by Hairy/Enhancer of Split, T-box, and Suppressor of Hairless proteins in the zebrafish segmentation clockQ34145324
Large-scale analysis of the regulatory architecture of the mouse genome with a transposon-associated sensorQ34172336
Evolutionary plasticity of segmentation clock networks.Q34190763
Analysis of her1 and her7 mutants reveals a spatio temporal separation of the somite clock moduleQ34314148
Computational representation of developmental genetic regulatory networksQ34420340
Intronic delay is essential for oscillatory expression in the segmentation clockQ34602627
FGF4 and FGF8 comprise the wavefront activity that controls somitogenesis.Q34652756
Optimization of a stochastically simulated gene network model via simulated annealing.Q35095781
Gene regulatory logic for reading the Sonic Hedgehog signaling gradient in the vertebrate neural tubeQ35700673
The Her7 node modulates the network topology of the zebrafish segmentation clock via sequestration of the Hes6 hub.Q35741905
Transcriptional regulation by the numbers: models.Q36083228
Crosstalk between Fgf and Wnt signaling in the zebrafish tailbud.Q36177067
Long-range downstream enhancers are essential for Pax6 expressionQ36661860
Animal transcription networks as highly connected, quantitative continuaQ37947741
Short-lived Her proteins drive robust synchronized oscillations in the zebrafish segmentation clockQ39383305
Two linked hairy/Enhancer of split-related zebrafish genes, her1 and her7, function together to refine alternating somite boundaries.Q39608214
Protein dynamics in drug combinations: a linear superposition of individual-drug responsesQ39731018
Completing the set of h/E(spl) cyclic genes in zebrafish: her12 and her15 reveal novel modes of expression and contribute to the segmentation clock.Q40245530
Control of her1 expression during zebrafish somitogenesis by a delta-dependent oscillator and an independent wave-front activityQ40443832
Fgf/MAPK signalling is a crucial positional cue in somite boundary formationQ40673345
Pairwise agonist scanning predicts cellular signaling responses to combinatorial stimuliQ41493018
Somitogenesis in the anole lizard and alligator reveals evolutionary convergence and divergence in the amniote segmentation clock.Q42629116
Requirement of multiple lysine residues for the transcriptional activity and the instability of Hes7.Q42813176
Accelerating the tempo of the segmentation clock by reducing the number of introns in the Hes7 geneQ43669340
her1 and the notch pathway function within the oscillator mechanism that regulates zebrafish somitogenesisQ43903112
Anterior and posterior waves of cyclic her1 gene expression are differentially regulated in the presomitic mesoderm of zebrafishQ44538271
her11 is involved in the somitogenesis clock in zebrafishQ45017372
tortuga refines Notch pathway gene expression in the zebrafish presomitic mesoderm at the post-transcriptional levelQ46093519
Segment number and axial identity in a segmentation clock period mutantQ47073670
her1 and her13.2 are jointly required for somitic border specification along the entire axis of the fish embryoQ47073860
Oscillatory expression of Hes1, p53, and NF-kappaB driven by transcriptional time delaysQ47672822
Avian hairy gene expression identifies a molecular clock linked to vertebrate segmentation and somitogenesisQ48041941
The elongation rate of RNA polymerase II in zebrafish and its significance in the somite segmentation clock.Q50769850
Autoinhibition with transcriptional delay: a simple mechanism for the zebrafish somitogenesis oscillator.Q52010517
Hairy/E(spl)-related (Her) genes are central components of the segmentation oscillator and display redundancy with the Delta/Notch signaling pathway in the formation of anterior segmental boundaries in the zebrafish.Q52118960
FGF signaling controls somite boundary position and regulates segmentation clock control of spatiotemporal Hox gene activation.Q52130820
Reliability of frequency and amplitude decoding in gene regulation.Q53382209
P433issue2
P407language of work or nameEnglishQ1860
P1104number of pages14
P304page(s)725-738
P577publication date2014-03-24
P1433published inGeneticsQ3100575
P1476titleModeling the zebrafish segmentation clock's gene regulatory network constrained by expression data suggests evolutionary transitions between oscillating and nonoscillating transcription
P478volume197

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cites work (P2860)
Q98286429Geometric models for robust encoding of dynamical information into embryonic patterns
Q46713018Pnrc2 regulates 3'UTR-mediated decay of segmentation clock-associated transcripts during zebrafish segmentation
Q91562404Pumilio response and AU-rich elements drive rapid decay of Pnrc2-regulated cyclic gene transcripts
Q36127626Sumoylation of Hes6 Regulates Protein Degradation and Hes1-Mediated Transcription
Q47829020The kinetics in mathematical models on segmentation clock genes in zebrafish.

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