Insect cells as hosts for the expression of recombinant glycoproteins.

scientific article

Insect cells as hosts for the expression of recombinant glycoproteins. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1012852562
P356DOI10.1023/A:1026488408951
P698PubMed publication ID10612411

P50authorIain B. WilsonQ55416045
Erika StaudacherQ43199918
Friedrich AltmannQ41883273
P2093author name stringL März
P2860cites workShear sensitivity of insect cells.Q52734521
Insect cell bioreactors.Q52734523
Scale up aspects of sparged insect-cell bioreactors.Q52734529
Downstream processing of insect cell cultures.Q52734534
Production of multidomain complement glycoproteins in insect cells.Q52734538
Safety aspects of insect cell culture.Q52734541
Complete structure of the carbohydrate moiety of stem bromelain. An application of the almond glycopeptidase for structural studies of glycopeptidesQ66961443
Peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase F cannot release glycans with fucose attached alpha 1----3 to the asparagine-linked N-acetylglucosamine residueQ67940170
Structure of a sugar chain of a protease inhibitor isolated from barbados pride (Caesalpinia pulcherrima Sw.) seedsQ69620554
The glycoprotein nature of phospholipase A2, hyaluronidase and acid phosphatase from honey-bee venomQ71156786
The asparagine-linked carbohydrate of honeybee venom hyaluronidaseQ72345349
N-linked glycosylation of Drosophila rhodopsin occurs exclusively in the amino-terminal domain and functions in rhodopsin maturationQ74432762
Evidence for N-glycosylation and ubiquitination of the prolactin receptor expressed in a baculovirus-insect cell systemQ42068016
Glycosylation of shaker potassium channel protein in insect cell culture and in Xenopus oocytesQ42068486
Engineering the assembly pathway of the baculovirus-insect cell expression systemQ42068494
Insect cell hosts for baculovirus expression vectors contain endogenous exoglycosidase activityQ42070380
Antibody production in silkworm cells and silkworm larvae infected with a dual recombinant Bombyx mori nuclear polyhedrosis virusQ42071040
Arylphorin from Manduca sexta: carbohydrate structure and immunological studiesQ42075624
Production of human alpha-interferon in silkworm using a baculovirus vectorQ42075774
The antigenicity of the carbohydrate moiety of an insect glycoprotein, honey-bee (Apis mellifera) venom phospholipase A2. The role of alpha 1,3-fucosylation of the asparagine-bound N-acetylglucosamineQ42086759
Core alpha1,3-fucose is a key part of the epitope recognized by antibodies reacting against plant N-linked oligosaccharides and is present in a wide variety of plant extractsQ42541806
Regulation of asparagine-linked oligosaccharide processing. Oligosaccharide processing in Aedes albopictus mosquito cellsQ43032728
Palmitoylation of Semliki Forest virus glycoproteins in insect cells (C6/36) occurs in an early compartment and is coupled to the cleavage of the precursor p62.Q43048496
Acylation of the Marburg virus glycoproteinQ44239313
Alpha 1-6(alpha 1-3)-difucosylation of the asparagine-bound N-acetylglucosamine in honeybee venom phospholipase A2.Q45364682
Immunological response of mice to the bovine respiratory syncytial virus fusion glycoprotein expressed in recombinant baculovirus infected insect cellsQ45757011
Long-lasting protection of sheep against bluetongue challenge after vaccination with virus-like particles: evidence for homologous and partial heterologous protection.Q45782124
Fatty acid acylation of the 67K envelope glycoprotein of a baculovirus: Autographa californica nuclear polyhedrosis virusQ45843830
Modeling assembly, aggregation, and chaperoning of immunoglobulin G production in insect cellsQ47445663
Biochemical analysis of proteins recognized by anti-HRP antibodies in Drosophila melanogaster: identification and characterization of neuron specific and male specific glycoproteinsQ47563116
The quality control of glycoprotein folding in the endoplasmic reticulum, a trip from trypanosomes to mammalsQ47708224
Economics of baculovirus-insect cell production systemsQ47745339
Perfusion bioreactors for the production of recombinant proteins in insect cellsQ47745368
Productivity of insect cells for recombinant proteinsQ47745389
Expression of recombinant anti-E-selectin single-chain Fv antibody fragments in stably transfected insect cell lines.Q47809308
Mutant analysis reveals an alternative pathway for N-linked glycosylation in Drosophila melanogasterQ47881468
Molecular and genetic analysis of the Drosophila mas-1 (mannosidase-1) gene which encodes a glycoprotein processing alpha 1,2-mannosidaseQ48074889
Occurrence of sialic acids in Drosophila melanogasterQ52443762
The structure of a neural specific carbohydrate epitope of horseradish peroxidase recognized by anti-horseradish peroxidase antiserum.Q52445118
Characterisation of oligosaccharides from Drosophila melanogaster glycoproteins.Q52447465
Glycosylation of chromosomal proteins: localization of O-linked N-acetylglucosamine in Drosophila chromatin.Q52452782
Expression and characterization of the Ha-ras p21 protein produced at high levels in the insect/baculovirus system.Q52454500
Kinetic comparison of peptide: N-glycosidases F and A reveals several differences in substrate specificity.Q52536543
Processing of asparagine-linked oligosaccharides in insect cells: evidence for alpha-mannosidase II.Q52537458
Expression of equine herpesvirus type 1 glycoprotein gp14 in Escherichia coli and in insect cells: a comparative study on protein processing and humoral immune responses.Q52542463
Mass spectrometric studies on the N-linked oligosaccharides of baculovirus-expressed mouse interleukin-3.Q52543502
Structure of the asn-linked oligosaccharides of apolipophorin III from the insect Locusta migratoria. Carbohydrate-linked 2-aminoethylphosphonate as a constituent of a glycoprotein.Q52545638
Primary structures of the N-linked carbohydrate chains from honeybee venom phospholipase A2.Q52546255
Coexpression of molecular chaperone BiP improves immunoglobulin solubility and IgG secretion from Trichoplusia ni insect cells.Q52552402
Insect cell cultivation: growth and kinetics.Q52734511
Medium design for insect cell culture.Q52734515
Post-translational modifications in insect cells.Q52734517
Lipid modifications of G proteins: alpha subunits are palmitoylatedQ24563070
Hepatitis C virus structural proteins assemble into viruslike particles in insect cellsQ27469539
Site-specific N-glycosylation and oligosaccharide structures of recombinant HIV-1 gp120 derived from a baculovirus expression systemQ28255278
Cloning and expression of the murine gene and chromosomal location of the human gene encoding N-acetylglucosaminyltransferase IQ28511486
Reconstitution and purification of eukaryotic initiation factor 2B (eIF2B) expressed in Sf21 insect cellsQ28575308
Mice lacking N-acetylglucosaminyltransferase I activity die at mid-gestation, revealing an essential role for complex or hybrid N-linked carbohydratesQ28588255
Biological roles of oligosaccharides: all of the theories are correctQ29616459
Human serotonin1B receptor expression in Sf9 cells: phosphorylation, palmitoylation, and adenylyl cyclase inhibitionQ30421359
N-glycosylation of recombinant human interferon-gamma produced in different animal expression systemsQ30430759
Structural analysis of N-glycans from allergenic grass, ragweed and tree pollens: core alpha1,3-linked fucose and xylose present in all pollens examined.Q30725139
Characterization of a UDP-Gal:Galbeta1-3GalNAc alpha1, 4-galactosyltransferase activity in a Mamestra brassicae cell lineQ31962312
High-level production of a functional immunoglobulin heterodimer in a baculovirus expression systemQ33593636
Fucose α1,3-Linked to the Core Region of Glycoprotein N-Glycans Creates an Important Epitope for IgE from Honeybee Venom Allergic IndividualsQ34306864
Structures of the N-linked oligosaccharides of the membrane glycoproteins from three lepidopteran cell lines (Sf-21, IZD-Mb-0503, Bm-N).Q34349881
Function of the two mannose 6-phosphate receptors in lysosomal enzyme transportQ34386154
Conformational implications of asparagine-linked glycosylationQ34805791
GDP-fucose: beta-N-acetylglucosamine (Fuc to (Fuc alpha 1----6GlcNAc)-Asn-peptide)alpha 1----3-fucosyltransferase activity in honeybee (Apis mellifica) venom glands. The difucosylation of asparagine-bound N-acetylglucosamineQ34805804
N-acetyl-beta-glucosaminidase accounts for differences in glycosylation of influenza virus hemagglutinin expressed in insect cells from a baculovirus vectorQ35862260
Production of human alkaline phosphatase, a secreted, glycosylated protein, from a baculovirus expression system and the attachment-dependent cell line Trichoplusia ni BTI-Tn 5B1-4 using a split-flow, air-lift bioreactorQ41518924
Expression of the glycosylphosphatidylinositol-linked complement-inhibiting protein CD59 antigen in insect cells using a baculovirus vectorQ41518962
The presence of UDP-N-acetylglucosamine:alpha-3-D-mannoside beta 1,2-N-acetylglucosaminyltransferase I activity in Spodoptera frugiperda cells (IPLB-SF-21AE) and its enhancement as a result of baculovirus infectionQ41533352
Biosynthesis and secretion of human interleukin 2 glycoprotein variants from baculovirus-infected Sf21 cells. Characterization of polypeptides and posttranslational modificationsQ41544468
Distinct N-glycan fucosylation potentials of three lepidopteran cell linesQ41610385
Novel pathways in complex-type oligosaccharide synthesis: new vistas opened by studies in invertebratesQ41655507
Detection of the lipid-linked precursor oligosaccharide of N-linked protein glycosylation in Drosophila melanogasterQ41665089
Characterization of oligosaccharide structures on a chimeric respiratory syncytial virus protein expressed in insect cell line Sf9.Q41690892
Carbohydrate variant of the recombinant beta-subunit of human choriogonadotropin expressed in baculovirus expression systemQ41691554
Expression of three recombinant proteins using baculovirus vectors in 23 insect cell linesQ41709678
Crossreactive carbohydrate determinantsQ41713453
Structure of O-glycosidically linked oligosaccharides synthesized by the insect cell line Sf9.Q41736215
Purification and properties of α-mannosidase II from Golgi-like membranes of baculovirus-infected Spodoptera frugiperda (IPLB-SF-21AE) cellsQ41840174
The role of tinman, a mesodermal cell fate gene, in axon pathfinding during the development of the transverse nerve in Drosophila.Q42058825
Baculovirus-mediated large-scale expression and purification of a polyhistidine-tagged rubella virus capsid proteinQ42060724
Differential fatty acid selection during biosynthetic S-acylation of a transmembrane protein (HEF) and other proteins in insect cells (Sf9) and in mammalian cells (CV1).Q42063711
Purification, biochemistry and molecular cloning of an insect glycosylasparaginase from Spodoptera frugiperdaQ42064060
High-level expression of five foreign genes by a single recombinant baculovirusQ42066487
Immunogenic and protective properties of chicken anaemia virus proteins expressed by baculovirusQ42067386
Baculovirus expression of the maize mitochondrial protein URF13 confers insecticidal activity in cell cultures and larvaeQ36241795
Posttranslational processing of recombinant human interferon-gamma in animal expression systemsQ36279636
Antibodies to horseradish peroxidase as specific neuronal markers in Drosophila and in grasshopper embryosQ36292831
Cloning and sequence analysis of GmII, a Drosophila melanogaster homologue of the cDNA encoding murine Golgi alpha-mannosidase II.Q36719612
Structural analysis and localization of the carbohydrate moieties of a soluble human interferon gamma receptor produced in baculovirus-infected insect cellsQ36745882
Cloning, expression, and hormonal regulation of an insect beta-N-acetylglucosaminidase geneQ36814342
Isolation and characterization of an alpha 1,2-mannosidase cDNA from the lepidopteran insect cell line Sf9.Q36860168
Microheterogeneity of the oligosaccharides carried by the recombinant bovine lactoferrin expressed in Mamestra brassicae cells.Q36875941
The 'yellow brick road' to branched complex N-glycansQ37135294
Rapid and efficient purification of native histidine-tagged protein expressed by recombinant vaccinia virusQ37604177
Complex asparagine-linked oligosaccharides are required for morphogenic events during post-implantation development.Q37631574
Expression of a Recombinant Baculovirus for Vitronectin in Insect Cells: Purification, Characterization of Post-translational Modifications and Functional Studies of the Recombinant ProteinQ38317399
Lectins as chaperones in glycoprotein foldingQ38331342
Baculovirus surface display: construction and screening of a eukaryotic epitope libraryQ38337245
Concanavalin A binding and endoglycosidase D resistance of beta1,2-xylosylated and alpha1,3-fucosylated plant and insect oligosaccharides.Q38338264
High-level expression and purification of a recombinant human alpha-1, 3-fucosyltransferase in baculovirus-infected insect cells.Q38343870
Differential N-glycan patterns of secreted and intracellular IgG produced in Trichoplusia ni cellsQ38346924
Neural-specific carbohydrate moiety shared by many surface glycoproteins in Drosophila and grasshopper embryos.Q39104424
Direct cloning into the Autographa californica nuclear polyhedrosis virus for generation of recombinant baculoviruses.Q40400699
Current methods for manipulating baculovirusesQ40533961
Large-scale insect and plant cell cultureQ40534650
Glycosylation and secretion of human tissue plasminogen activator in recombinant baculovirus-infected insect cellsQ40644152
Drosophila UDP-glucose:glycoprotein glucosyltransferase: sequence and characterization of an enzyme that distinguishes between denatured and native proteinsQ40806166
Optimising fed-batch production of recombinant proteins using the baculovirus expression vector systemQ40963459
N-Linked glycosylation of a baculovirus-expressed recombinant glycoprotein in insect larvae and tissue culture cellsQ41035528
Strict order of (Fuc to Asn-linked GlcNAc) fucosyltransferases forming core-difucosylated structures.Q41037223
Superior biologic activity of the recombinant bee venom allergen hyaluronidase expressed in baculovirus-infected insect cells as compared with Escherichia coliQ41040566
Stable expression of mammalian beta 1,4-galactosyltransferase extends the N-glycosylation pathway in insect cells.Q41041039
N-glycosylation of a baculovirus-expressed recombinant glycoprotein in three insect cell linesQ41041468
Human endothelin receptors ET(A) and ET(B) expressed in baculovirus-infected insect cells--direct application for signal transduction analysisQ41077265
Generation of a p10-based baculovirus expression vector in yeast with infectivity for insect larvae and insect cellsQ41077361
Stable insect cell cultures for recombinant protein productionQ41082229
Engineering the folding pathway of insect cells: generation of a stably transformed insect cell line showing improved folding of a recombinant membrane proteinQ41087856
More than silk and honey--or, can insect cells serve in the production of therapeutic glycoproteins?Q41095950
Expression of stable human O-glycan core 2 beta-1,6-N-acetylglucosaminyltransferase in Sf9 insect cellsQ41102270
Insect mucin-type glycoprotein: immunodetection of the O-glycosylated epitope in Drosophila melanogaster cells and tissuesQ41105970
Isolation and characterization of a class II alpha-mannosidase cDNA from lepidopteran insect cellsQ41130017
Modifying the insect cell N-glycosylation pathway with immediate early baculovirus expression vectors.Q41160004
Elongation of the N-glycans of fowl plague virus hemagglutinin expressed in Spodoptera frugiperda (Sf9) cells by coexpression of human beta 1,2-N-acetylglucosaminyltransferase I.Q41221793
Glycosylation in lepidopteran insect cells: identification of a beta 1-->4-N-acetylgalactosaminyltransferase involved in the synthesis of complex-type oligosaccharide chainsQ41221808
Stable expression of insect GABA receptors in insect cell lines. Promoters for efficient expression of Drosophila and mosquito Rdl GABA receptors in stably transformed mosquito cell lines.Q41227277
Baculovirus vectors for expression in insect cellsQ41238622
Expression and characterization of recombinant alpha-galactosidase in baculovirus-infected insect cellsQ41238882
Wild-type and insecticide-resistant homo-oligomeric GABA receptors of Drosophila melanogaster stably expressed in a Drosophila cell lineQ41243338
Intracellular compartmentalization of the glycoprotein B of herpesvirus Simian agent 8 expressed with a baculovirus vector in insect cellsQ41245076
Intrinsic glycosylation potentials of insect cell cultures and insect larvaeQ41287511
Insect cells contain an unusual, membrane-bound beta-N-acetylglucosaminidase probably involved in the processing of protein N-glycans.Q41324053
Effects of co-expressing chaperone BiP on functional antibody production in the baculovirus systemQ41420522
Glycosylation of recombinant prorenin in insect cells: the insect cell line Sf9 does not express the mannose 6-phosphate recognition signalQ41453846
Expression, glycosylation, and phosphorylation of human keratins 8 and 18 in insect cellsQ41486023
The alpha-subunits of G-proteins G12 and G13 are palmitoylated, but not amidically myristoylated.Q41487859
Characterization by electrospray mass spectrometry of human Ca(2+)-sensitive cytosolic phospholipase A2 produced in baculovirus-infected insect cellsQ41505239
Recombinant protein expression in a Drosophila cell line: comparison with the baculovirus systemQ41506444
Retarded processing of influenza virus hemagglutinin in insect cellsQ41509618
The oligosaccharides of influenza virus hemagglutinin expressed in insect cells by a baculovirus vectorQ41512139
Processing of asparagine-linked oligosaccharides in insect cells. N-acetylglucosaminyltransferase I and II activities in cultured lepidopteran cellsQ41512282
Expression of human interferon-alpha 2 in Sf9 cells. Characterization of O-linked glycosylation and protein heterogeneitiesQ41517464
Expression of human interferon omega 1 in Sf9 cells. No evidence for complex-type N-linked glycosylation or sialylationQ41517475
Comparison of oligosaccharide processing among various insect cell lines expressing a secreted glycoproteinQ41517927
P433issue2
P921main subjectinsectQ1390
P304page(s)109-123
P577publication date1999-02-01
P1433published inGlycoconjugate JournalQ15753886
P1476titleInsect cells as hosts for the expression of recombinant glycoproteins
P478volume16

Reverse relations

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Q40763867Sialylation of N-glycans on the recombinant proteins expressed by a baculovirus-insect cell system under beta-N-acetylglucosaminidase inhibition
Q33511748Soluble CD36 ectodomain binds negatively charged diacylglycerol ligands and acts as a co-receptor for TLR2.
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