Characterization of the GXXXG motif in the first transmembrane segment of Japanese encephalitis virus precursor membrane (prM) protein

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Characterization of the GXXXG motif in the first transmembrane segment of Japanese encephalitis virus precursor membrane (prM) protein is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1027168484
P356DOI10.1186/1423-0127-17-39
P932PMC publication ID2890656
P698PubMed publication ID20492732
P5875ResearchGate publication ID44620959

P2093author name stringSuh-Chin Wu
Ying-Ju Lin
Jia-Guan Peng
P2860cites workAmino acid distributions in integral membrane protein structuresQ30168203
Alanine insertion scanning mutagenesis of lactose permease transmembrane helicesQ30428848
Insect cells as hosts for the expression of recombinant glycoproteins.Q33804553
Noninfectious recombinant antigen for detection of St. Louis encephalitis virus-specific antibodies in serum by enzyme-linked immunosorbent assayQ37576107
Interactions between the transmembrane segments of the alphavirus E1 and E2 proteins play a role in virus budding and fusionQ39732657
Formation of bovine viral diarrhea virus E1-E2 heterodimers is essential for virus entry and depends on charged residues in the transmembrane domainsQ39946464
The conserved glycine residues in the transmembrane domain of the Semliki Forest virus fusion protein are not required for assembly and fusion.Q40468559
Single point mutation in tick-borne encephalitis virus prM protein induces a reduction of virus particle secretionQ40510997
Secretion of noninfectious dengue virus-like particles and identification of amino acids in the stem region involved in intracellular retention of envelope proteinQ40514541
Histidine 39 in the dengue virus type 2 M protein has an important role in virus assemblyQ40520518
Enhancing biosynthesis and secretion of premembrane and envelope proteins by the chimeric plasmid of dengue virus type 2 and Japanese encephalitis virusQ40564204
Murray Valley encephalitis virus recombinant subviral particles protect mice from lethal challenge with virulent wild-type virusQ40579012
Dengue type 2 virus subviral extracellular particles produced by a stably transfected mammalian cell line and their evaluation for a subunit vaccineQ40589716
Complete nucleotide sequence and cell-line multiplication pattern of the attenuated variant CH2195LA of Japanese encephalitis virusQ40609321
Japanese encephalitis virus antigenic variants with characteristic differences in neutralization resistance and mouse virulenceQ41060173
Molecular organization of a recombinant subviral particle from tick-borne encephalitis virusQ41630846
Ala-insertion scanning mutagenesis of the glycophorin A transmembrane helix: a rapid way to map helix-helix interactions in integral membrane proteinsQ42185560
Statistical analysis of amino acid patterns in transmembrane helices: the GxxxG motif occurs frequently and in association with beta-branched residues at neighboring positions.Q52081092
Charged residues in the transmembrane domains of hepatitis C virus glycoproteins play a major role in the processing, subcellular localization, and assembly of these envelope proteinsQ27469653
Mapping of functional elements in the stem-anchor region of tick-borne encephalitis virus envelope protein EQ27469713
West Nile virus recombinant DNA vaccine protects mouse and horse from virus challenge and expresses in vitro a noninfectious recombinant antigen that can be used in enzyme-linked immunosorbent assaysQ27469785
Histidine at Residue 99 and the Transmembrane Region of the Precursor Membrane prM Protein Are Important for the prM-E Heterodimeric Complex Formation of Japanese Encephalitis VirusQ27469836
Generation and Characterization of a Mammalian Cell Line Continuously Expressing Japanese Encephalitis Virus Subviral ParticlesQ27469890
Role of the transmembrane domains of prM and E proteins in the formation of yellow fever virus envelope.Q27473078
A functional epitope determinant on domain III of the Japanese encephalitis virus envelope protein interacted with neutralizing-antibody combining sitesQ27473104
Construction and Mutagenesis of an Artificial Bicistronic Tick-Borne Encephalitis Virus Genome Reveals an Essential Function of the Second Transmembrane Region of Protein E in Flavivirus AssemblyQ27477719
Transmembrane Domains of Hepatitis C Virus Envelope Glycoproteins: Residues Involved in E1E2 Heterodimerization and Involvement of These Domains in Virus EntryQ27478363
Synthesis and secretion of recombinant tick-borne encephalitis virus protein E in soluble and particulate formQ27480299
Proteolytic activation of tick-borne encephalitis virus by furinQ27480892
The transmembrane domains of hepatitis C virus envelope glycoproteins E1 and E2 play a major role in heterodimerizationQ27622511
Visualization of membrane protein domains by cryo-electron microscopy of dengue virusQ27642288
A structural perspective of the flavivirus life cycleQ29616269
P407language of work or nameEnglishQ1860
P921main subjectencephalitisQ199615
transmembrane proteinQ424204
Japanese encephalitisQ738292
Japanese encephalitis virusQ19838331
P304page(s)39
P577publication date2010-05-24
P1433published inJournal of Biomedical ScienceQ15759332
P1476titleCharacterization of the GXXXG motif in the first transmembrane segment of Japanese encephalitis virus precursor membrane (prM) protein
P478volume17

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cites work (P2860)
Q26700092A Single Amino Acid Substitution in the M Protein Attenuates Japanese Encephalitis Virus in Mammalian Hosts
Q66678719Directional entry and release of Zika virus from polarized epithelial cells
Q56347959Establishment of Baculovirus-Expressed VLPs Induced Syncytial Formation Assay for Flavivirus Antiviral Screening
Q34057796Glutamic acid at residue 125 of the prM helix domain interacts with positively charged amino acids in E protein domain II for Japanese encephalitis virus-like-particle production
Q56798166Mosquito-borne flaviviruses: overview of viral life-cycle and host–virus interactions
Q38364867Post-translational regulation and modifications of flavivirus structural proteins
Q24324019Protein oligomerization mediated by the transmembrane carboxyl terminal domain of Bcl-XL
Q41890205Sequence-dependent backbone dynamics of a viral fusogen transmembrane helix
Q35584131The I22V and L72S substitutions in West Nile virus prM protein promote enhanced prM/E heterodimerisation and nucleocapsid incorporation
Q26865109Transmembrane helix dimerization: beyond the search for sequence motifs