Engineering β1,4-galactosyltransferase I to reduce secretion and enhance N-glycan elongation in insect cells

scientific article

Engineering β1,4-galactosyltransferase I to reduce secretion and enhance N-glycan elongation in insect cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.JBIOTEC.2014.11.013
P932PMC publication ID4278940
P698PubMed publication ID25462875
P5875ResearchGate publication ID269175742

P50authorDonald L JarvisQ59033612
Kay-Hooi KhooQ62806297
Hideaki Mabashi-asazumaQ42767514
P2093author name stringChristoph Geisler
Chu-Wei Kuo
P2860cites workMolecular cloning of a cDNA encoding a novel human leukocyte alpha-1,3-fucosyltransferase capable of synthesizing the sialyl Lewis x determinantQ24316888
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Fucosyltransferase substrate specificity and the order of fucosylation in invertebratesQ33209986
Beta-1,4-galactosylation of N-glycans is a complex processQ33783691
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A new insect cell glycoengineering approach provides baculovirus-inducible glycogene expression and increases human-type glycosylation efficiencyQ33893766
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The impact of glycosylation on the pharmacokinetics of a TNFR2:Fc fusion protein expressed in Glycoengineered Pichia Pastoris.Q45958455
Alteration of terminal glycosylation sequences on N-linked oligosaccharides of Chinese hamster ovary cells by expression of beta-galactoside alpha 2,6-sialyltransferase.Q46007488
Expression of natural human β1,4-GalT1 variants and of non-mammalian homologues in plants leads to differences in galactosylation of N-glycansQ46857785
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Different glycosyltransferases are differentially processed for secretion, dimerization, and autoglycosylation.Q51833327
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Galactosyltransferase--still up and runningQ35138095
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Substrate specificities and intracellular distributions of three N-glycan processing enzymes functioning at a key branch point in the insect N-glycosylation pathwayQ35801895
The membrane spanning domain of beta-1,4-galactosyltransferase specifies trans Golgi localizationQ35934419
Impact of a human CMP-sialic acid transporter on recombinant glycoprotein sialylation in glycoengineered insect cellsQ36491777
Protein N-glycosylation in the baculovirus-insect cell expression system and engineering of insect cells to produce "mammalianized" recombinant glycoproteins.Q36601827
Structure and function of beta -1,4-galactosyltransferaseQ36627413
Improved glycosylation of a foreign protein by Tn-5B1-4 cells engineered to express mammalian glycosyltransferases.Q36815622
Nucleotide sequence and temporal expression of a baculovirus regulatory geneQ36889543
A novel baculovirus vector for the production of nonfucosylated recombinant glycoproteins in insect cellsQ37573768
Localization of Golgi-resident glycosyltransferasesQ37591235
How Golgi glycosylation meets and needs trafficking: the case of the COG complexQ37813005
Use of lectins in analysis of glycoconjugatesQ38312626
The relationship between ST6Gal I Golgi retention and its cleavage-secretionQ38318446
Regulating cell surface glycosylation by small molecule control of enzyme localizationQ38346424
A fused lobes gene encodes the processing beta-N-acetylglucosaminidase in Sf9 cellsQ39262654
A transgenic insect cell line engineered to produce CMP-sialic acid and sialylated glycoproteins.Q39462326
Novel baculovirus expression vectors that provide sialylation of recombinant glycoproteins in lepidopteran insect cells.Q39603349
Subcellular organization of glycosylation in mammalian cellsQ39668642
A secreted type of beta1,6 N-acetylglucosaminyltransferase V (GnT-V), a novel angiogenesis inducer, is regulated by gamma-secretase.Q40201542
Mammalian glycosyltransferase expression allows sialoglycoprotein production by baculovirus-infected insect cellsQ40794881
Engineering lepidopteran insect cells for sialoglycoprotein production by genetic transformation with mammalian beta 1,4-galactosyltransferase and alpha 2,6-sialyltransferase genesQ40826999
In vivo synthesis of mammalian-like, hybrid-type N-glycans in Pichia pastorisQ40833188
Electrophoretic analysis of glycoprotein glycans produced by lepidopteran insect cells infected with an immediate early recombinant baculovirus encoding mammalian beta1,4-galactosyltransferaseQ40835288
The cytoplasmic, transmembrane, and stem regions of glycosyltransferases specify their in vivo functional sublocalization and stability in the GolgiQ40912913
Stable expression of mammalian beta 1,4-galactosyltransferase extends the N-glycosylation pathway in insect cells.Q41041039
Secretion of alpha1,3-galactosyltransferase by cultured cells and presence of enzyme in animal seraQ41057192
Modifying the insect cell N-glycosylation pathway with immediate early baculovirus expression vectors.Q41160004
Insect cells contain an unusual, membrane-bound beta-N-acetylglucosaminidase probably involved in the processing of protein N-glycans.Q41324053
Processing of asparagine-linked oligosaccharides in insect cells. N-acetylglucosaminyltransferase I and II activities in cultured lepidopteran cellsQ41512282
The signal anchor and stem regions of the beta-galactoside alpha 2,6-sialyltransferase may each act to localize the enzyme to the Golgi apparatusQ41628848
OPTIMIZER: a web server for optimizing the codon usage of DNA sequencesQ41769919
A method for producing recombinant baculovirus expression vectors at high frequency.Q42070060
A baculovirus expression vector derived from the basic protein promoter of Autographa californica nuclear polyhedrosis virusQ42073143
Involvement of a cysteine protease in the secretion process of human xylosyltransferase I.Q43144436
P921main subjectinsectQ1390
P304page(s)52-65
P577publication date2014-11-25
P1433published inJournal of BiotechnologyQ6294860
P1476titleEngineering β1,4-galactosyltransferase I to reduce secretion and enhance N-glycan elongation in insect cells
P478volume193

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cites work (P2860)
Q47822735CRISPR-Cas9 vectors for genome editing and host engineering in the baculovirus-insect cell system.
Q36828495Characterization of an Sf-rhabdovirus-negative Spodoptera frugiperda cell line as an alternative host for recombinant protein production in the baculovirus-insect cell system
Q47659258Combinatorial genome and protein engineering yields monoclonal antibodies with hypergalactosylation from CHO cells.
Q47840988Expression and Characterization of Human β-1, 4-Galactosyltransferase 1 (β4GalT1) Using Silkworm-Baculovirus Expression System
Q33684020N-Glycan Modification of a Recombinant Protein via Coexpression of Human Glycosyltransferases in Silkworm Pupae
Q60045816Sequencing the mosaic genome of Brahman cattle identifies historic and recent introgression including polled
Q38951951Synthetic gene design-The rationale for codon optimization and implications for molecular pharming in plants.
Q36361549The sweet branch of metabolic engineering: cherry-picking the low-hanging sugary fruits

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