Sindbis virus entry into cells triggers apoptosis by activating sphingomyelinase, leading to the release of ceramide

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Sindbis virus entry into cells triggers apoptosis by activating sphingomyelinase, leading to the release of ceramide is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.74.14.6425-6432.2000
P932PMC publication ID112150
P698PubMed publication ID10864654

P50authorDiane E. GriffinQ4793714
P2093author name stringS Chatterjee
J T Jan
P2860cites workFAN, a novel WD-repeat protein, couples the p55 TNF-receptor to neutral sphingomyelinaseQ24323995
Molecular cloning and characterization of a full-length complementary DNA encoding human acid ceramidase. Identification Of the first molecular lesion causing Farber diseaseQ24336488
PKC zeta is a molecular switch in signal transduction of TNF-alpha, bifunctionally regulated by ceramide and arachidonic acidQ24568285
Sphingolipid-dependent fusion of Semliki Forest virus with cholesterol-containing liposomes requires both the 3-hydroxyl group and the double bond of the sphingolipid backboneQ27478474
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Induction of apoptosis by Sindbis virus occurs at cell entry and does not require virus replication.Q33825385
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Thiol agents and Bcl-2 identify an alphavirus-induced apoptotic pathway that requires activation of the transcription factor NF-kappa B.Q36236221
Suppression of steady-state, but not stimulus-induced NF-kappaB activity inhibits alphavirus-induced apoptosisQ36256156
Cytokine response modifier A (CrmA) inhibits ceramide formation in response to tumor necrosis factor (TNF)-alpha: CrmA and Bcl-2 target distinct components in the apoptotic pathwayQ36376514
Bc1-2 protects mice against fatal alphavirus encephalitisQ37605545
An update of the enzymology and regulation of sphingomyelin metabolismQ37923512
Tumor necrosis factor-alpha (TNF-alpha) signal transduction through ceramide. Dissociation of growth inhibitory effects of TNF-alpha from activation of nuclear factor-kappa B.Q38316784
Sphingomyelinases and Niemann-Pick diseaseQ39501156
Sindbis virus induces apoptosis through a caspase-dependent, CrmA-sensitive pathway.Q39577253
The transmembrane domains of Sindbis virus envelope glycoproteins induce cell deathQ39578400
The entry of enveloped viruses into cells by endocytosisQ40174418
Interaction of Sindbis virus with liposomal model membranesQ40306920
Ceramide: an intracellular signal for apoptosisQ40497600
The sphingomyelin pathway in tumor necrosis factor and interleukin-1 signalingQ40751632
Membrane fusion of Semliki Forest virus requires sphingolipids in the target membraneQ40792231
Neutral sphingomyelinase.Q40850174
Ceramide-activated protein phosphatase: partial purification and relationship to protein phosphatase 2A.Q40857568
TNF receptor death domain-associated proteins TRADD and FADD signal activation of acid sphingomyelinaseQ41052331
Apoptosis induced by a postbinding step of vaccinia virus entry into Chinese hamster ovary cellsQ41059681
Activation of acid sphingomyelinase by interleukin-1 (IL-1) requires the IL-1 receptor accessory proteinQ41083675
Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.Q41218044
Bax-independent inhibition of apoptosis by Bcl-XL.Q41229247
Phosphorylation of Raf by ceramide-activated protein kinaseQ41270560
Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase.Q41440948
Renaturation and tumor necrosis factor-alpha stimulation of a 97-kDa ceramide-activated protein kinaseQ41493252
Conversion of lytic to persistent alphavirus infection by the bcl-2 cellular oncogeneQ41572703
Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis.Q42555356
CAR1, a TNFR-related protein, is a cellular receptor for cytopathic avian leukosis-sarcoma viruses and mediates apoptosisQ42806740
Protein kinase C zeta isoform is critical for kappa B-dependent promoter activation by sphingomyelinaseQ42835297
Phosphorylation and dephosphorylation events play critical roles in Sindbis virus maturationQ45774665
Sphingolipids activate membrane fusion of Semliki Forest virus in a stereospecific mannerQ45787419
Basis of neurovirulence in Sindbis virus encephalomyelitis of miceQ45832181
Role of the immune response in recovery from Sindbis virus encephalitis in miceQ45888076
Coupling of the p75 neurotrophin receptor to sphingolipid signaling.Q47825981
Fumonisins: fungal toxins that shed light on sphingolipid functionQ47986534
Distinct adapter proteins mediate acid versus neutral sphingomyelinase activation through the p55 receptor for tumor necrosis factorQ47992357
Ceramide quantitation: evaluation of a mixed micellar assay using E. coli diacylglycerol kinase.Q54613087
Inhibition of Tumor Necrosis Factor Signal Transduction in Endothelial Cells by DimethylaminopurineQ58112582
c-Jun is a downstream target for ceramide-activated protein phosphatase in A431 cells.Q64967336
TNF activates NF-kappa B by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdownQ67505708
Human acid sphingomyelinase from human urineQ70192142
Programmed cell death induced by ceramideQ70619078
Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signalingQ72710788
Characteristics and partial purification of a novel cytosolic, magnesium-independent, neutral sphingomyelinase activated in the early signal transduction of 1 alpha,25-dihydroxyvitamin D3-induced HL-60 cell differentiationQ72772789
Substrate recognition by ceramide-activated protein kinase. Evidence that kinase activity is proline-directedQ72932271
Tumor necrosis factor induces ceramide oscillations and negatively controls sphingolipid synthases by caspases in apoptotic Kym-1 cellsQ77545172
P433issue14
P407language of work or nameEnglishQ1860
P921main subjectapoptotic processQ14599311
ceramidesQ424213
Sindbis virusQ2302993
P304page(s)6425-6432
P577publication date2000-07-01
P1433published inJournal of VirologyQ1251128
P1476titleSindbis virus entry into cells triggers apoptosis by activating sphingomyelinase, leading to the release of ceramide
P478volume74

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