| scholarly article | Q13442814 |
| P356 | DOI | 10.3324/HAEMATOL.2009.015628 |
| P8608 | Fatcat ID | release_jlabmc5ykff6jc34epkeclnjme |
| P932 | PMC publication ID | 2864384 |
| P698 | PubMed publication ID | 20015878 |
| P5875 | ResearchGate publication ID | 40693260 |
| P50 | author | Adrian Harris | Q37374768 |
| Daniel J. Peet | Q37382862 | ||
| Sally K Martin | Q61156962 | ||
| Stan Gronthos | Q61478070 | ||
| Andrew Zannettino | Q62831692 | ||
| P2093 | author name string | Nobutaka Fujii | |
| Peter Diamond | |||
| Luen Bik To | |||
| Sharon A Williams | |||
| P2860 | cites work | Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension | Q24307473 |
| Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method | Q25938999 | ||
| Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases | Q28139317 | ||
| The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages | Q28143066 | ||
| Levels of hypoxia-inducible factor-1alpha independently predict prognosis in patients with lymph node negative breast carcinoma | Q28181979 | ||
| Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch | Q28217194 | ||
| Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion | Q29547317 | ||
| Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1 | Q29615241 | ||
| Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes | Q29617594 | ||
| Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours | Q29618396 | ||
| Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation | Q29619687 | ||
| In vivo antitumor effects of the mTOR inhibitor CCI-779 against human multiple myeloma cells in a xenograft model | Q33362103 | ||
| Oxygen tension regulates the expression of the platelet-derived growth factor-B chain gene in human endothelial cells | Q34259539 | ||
| Bone marrow angiogenesis and progression in multiple myeloma. | Q34292940 | ||
| Hypoxia-mediated induction of acidic/basic fibroblast growth factor and platelet-derived growth factor in mononuclear phagocytes stimulates growth of hypoxic endothelial cells | Q34349638 | ||
| The small-molecule VEGF receptor inhibitor pazopanib (GW786034B) targets both tumor and endothelial cells in multiple myeloma | Q35540030 | ||
| Targeting PKC in multiple myeloma: in vitro and in vivo effects of the novel, orally available small-molecule inhibitor enzastaurin (LY317615.HCl). | Q35628888 | ||
| Bone marrow angiogenesis in multiple myeloma | Q36343529 | ||
| Hypoxia inducible factor-2alpha in cancer. | Q36778663 | ||
| Biology of hypoxia-inducible factor-2alpha in development and disease | Q37079716 | ||
| Regulation of endothelial cell branching morphogenesis by endogenous chemokine stromal-derived factor-1 | Q77869788 | ||
| Hypoxia-induced production of stromal cell-derived factor 1 (CXCL12) and vascular endothelial growth factor by synovial fibroblasts | Q78387178 | ||
| Targeted disruption of the CXCL12/CXCR4 axis inhibits osteolysis in a murine model of myeloma-associated bone loss | Q37427808 | ||
| A low-molecular-weight inhibitor against the chemokine receptor CXCR4: a strong anti-HIV peptide T140. | Q39507599 | ||
| Targeting angiogenesis via a c-Myc/hypoxia-inducible factor-1alpha-dependent pathway in multiple myeloma | Q39840627 | ||
| Stromal cell-derived factor-1alpha (SDF-1alpha/CXCL12)-enhanced angiogenesis of human basal cell carcinoma cells involves ERK1/2-NF-kappaB/interleukin-6 pathway | Q39930243 | ||
| The anti-cancer drug lenalidomide inhibits angiogenesis and metastasis via multiple inhibitory effects on endothelial cell function in normoxic and hypoxic conditions | Q39937690 | ||
| Tumor angiogenesis is associated with plasma levels of stromal-derived factor-1alpha in patients with multiple myeloma. | Q40200955 | ||
| Irradiation and hypoxia promote homing of haematopoietic progenitor cells towards gliomas by TGF-beta-dependent HIF-1alpha-mediated induction of CXCL12. | Q40256595 | ||
| Mechanistic investigation and implications of photodynamic therapy induction of vascular endothelial growth factor in prostate cancer. | Q40272822 | ||
| The involvement of stromal derived factor 1alpha in homing and progression of multiple myeloma in the 5TMM model. | Q40289832 | ||
| Stromal cell-derived factor-1alpha and CXCR4 expression in hemangioblastoma and clear cell-renal cell carcinoma: von Hippel-Lindau loss-of-function induces expression of a ligand and its receptor | Q40396846 | ||
| Elevated serum levels of stromal-derived factor-1alpha are associated with increased osteoclast activity and osteolytic bone disease in multiple myeloma patients. | Q40449381 | ||
| A single treatment with microcapsules containing a CXCR4 antagonist suppresses pulmonary metastasis of murine melanoma | Q40543358 | ||
| Integrin alpha4beta1 involvement in stromal cell-derived factor-1alpha-promoted myeloma cell transendothelial migration and adhesion: role of cAMP and the actin cytoskeleton in adhesion. | Q40578173 | ||
| A novel triple-modality reporter gene for whole-body fluorescent, bioluminescent, and nuclear noninvasive imaging | Q40579830 | ||
| Inhibition of hypoxia-inducible factor is sufficient for growth suppression of VHL-/- tumors. | Q40585447 | ||
| Predominant role of hypoxia-inducible transcription factor (Hif)-1alpha versus Hif-2alpha in regulation of the transcriptional response to hypoxia. | Q40626158 | ||
| Expression of stromal cell-derived factor 1 and CXCR4 ligand receptor system in pancreatic cancer: a possible role for tumor progression | Q40853389 | ||
| Transcriptional regulation of mouse granulocyte-macrophage colony-stimulating factor/IL-3 locus | Q41330968 | ||
| Hypoxia regulates vascular endothelial growth factor gene expression in endothelial cells. Identification of a 5' enhancer | Q42481577 | ||
| Chemokine stromal cell-derived factor-1alpha modulates VLA-4 integrin-mediated multiple myeloma cell adhesion to CS-1/fibronectin and VCAM-1. | Q43518303 | ||
| Role of the hypoxic bone marrow microenvironment in 5T2MM murine myeloma tumor progression. | Q46541959 | ||
| Bortezomib inhibits tumor adaptation to hypoxia by stimulating the FIH-mediated repression of hypoxia-inducible factor-1. | Q46823917 | ||
| Prognostic significance of HIF-1 alpha overexpression in human pancreatic cancer | Q47188426 | ||
| CXCL12 and vascular endothelial growth factor synergistically induce neoangiogenesis in human ovarian cancers. | Q47853213 | ||
| Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia | Q48072985 | ||
| The transcriptional activator hypoxia inducible factor 2 (HIF-2/EPAS-1) regulates the oxygen-dependent expression of erythropoietin in cortical astrocytes. | Q48421828 | ||
| Mobilization of myeloma cells involves SDF-1/CXCR4 signaling and downregulation of VLA-4. | Q52552791 | ||
| Expression and function of chemokine receptors in human multiple myeloma. | Q54795137 | ||
| Vascular endothelial growth factor and interleukin-6 in paracrine tumor-stromal cell interactions in multiple myeloma | Q60652055 | ||
| Augmentation of in vitro human marrow erythropoiesis under physiological oxygen tensions is mediated by monocytes and T lymphocytes | Q68813876 | ||
| Prognostic value of bone marrow angiogenesis in multiple myeloma | Q74216118 | ||
| P433 | issue | 5 | |
| P921 | main subject | hypoxia | Q105688 |
| multiple myeloma | Q467635 | ||
| P304 | page(s) | 776-784 | |
| P577 | publication date | 2009-12-16 | |
| P1433 | published in | Haematologica | Q5638209 |
| P1476 | title | Hypoxia-inducible factor-2 is a novel regulator of aberrant CXCL12 expression in multiple myeloma plasma cells | |
| P478 | volume | 95 |
| Q38800369 | A DNA-binding Molecule Targeting the Adaptive Hypoxic Response in Multiple Myeloma Has Potent Antitumor Activity |
| Q92899471 | AGTR1 promotes lymph node metastasis in breast cancer by upregulating CXCR4/SDF-1α and inducing cell migration and invasion |
| Q37956524 | Biological aspects of angiogenesis in multiple myeloma. |
| Q38472331 | CXCL12/CXCR4: a symbiotic bridge linking cancer cells and their stromal neighbors in oncogenic communication networks |
| Q42146660 | Cell Trafficking in Multiple Myeloma |
| Q52676274 | Daratumumab augments alloreactive natural killer cell cytotoxicity towards CD38+ multiple myeloma cell lines in a biochemical context mimicking tumour microenvironment conditions. |
| Q38672565 | Effect of hypoxia-inducible factors in normal and leukemic stem cell regulation and their potential therapeutic impact. |
| Q64090632 | Hypoxia as a barrier to immunotherapy in pancreatic adenocarcinoma |
| Q48207902 | Hypoxia favors the generation of human plasma cells |
| Q31118586 | Hypoxia induced impairment of NK cell cytotoxicity against multiple myeloma can be overcome by IL-2 activation of the NK cells. |
| Q51636063 | Hypoxia inducible factor (HIF)-2α accelerates disease progression in mouse models of leukemia and lymphoma but is not a poor prognosis factor in human AML. |
| Q36057606 | Hypoxia promotes dissemination of multiple myeloma through acquisition of epithelial to mesenchymal transition-like features |
| Q39078376 | Hypoxia reduces CD138 expression and induces an immature and stem cell-like transcriptional program in myeloma cells |
| Q36717999 | Identification of an ABCB1 (P-glycoprotein)-positive carfilzomib-resistant myeloma subpopulation by the pluripotent stem cell fluorescent dye CDy1 |
| Q38769432 | Integration of hypoxic HIF-α signaling in blood cancers |
| Q38724150 | Loss of dual-specificity phosphatase-2 promotes angiogenesis and metastasis via up-regulation of interleukin-8 in colon cancer. |
| Q61798674 | Molecular Players in Hematologic Tumor Cell Trafficking |
| Q38035044 | Molecular mechanisms of effectiveness of novel therapies in multiple myeloma |
| Q38697483 | Multiple Myeloma Cells Express Key Immunoregulatory Cytokines and Modulate the Monocyte Migratory Response. |
| Q36725401 | Multiple myeloma in the marrow: pathogenesis and treatments. |
| Q38151195 | Myeloma stem cell concepts, heterogeneity and plasticity of multiple myeloma. |
| Q42244787 | Neoplastic plasma cells generate an inflammatory environment within bone marrow and markedly alter the distribution of T cells between lymphoid compartments |
| Q38073136 | Notch-directed microenvironment reprogramming in myeloma: a single path to multiple outcomes |
| Q42793018 | Novel drugs for the treatment of multiple myeloma |
| Q34651839 | PARP-1 and YY1 are important novel regulators of CXCL12 gene transcription in rat pancreatic beta cells |
| Q38930119 | Potential targeting of B7-H4 for the treatment of cancer. |
| Q90239509 | Primary prostate cancer educates bone stroma through exosomal pyruvate kinase M2 to promote bone metastasis |
| Q35680177 | SDF-1α stiffens myeloma bone marrow mesenchymal stromal cells through the activation of RhoA-ROCK-Myosin II. |
| Q48955308 | Targeted knockdown of DJ-1 induces multiple myeloma cell death via KLF6 upregulation |
| Q33917555 | Targeting of multiple myeloma-related angiogenesis by miR-199a-5p mimics: in vitro and in vivo anti-tumor activity. |
| Q26799499 | Targeting the Pim kinases in multiple myeloma |
| Q57171912 | The Lipid Side of Bone Marrow Adipocytes: How Tumor Cells Adapt and Survive in Bone |
| Q37884379 | The emerging role of hypoxia, HIF-1 and HIF-2 in multiple myeloma. |
| Q35079365 | The left-right Pitx2 pathway drives organ-specific arterial and lymphatic development in the intestine |
| Q92360633 | The role of hypoxia-inducible factors in neovascular age-related macular degeneration: a gene therapy perspective |
| Q89167704 | Therapeutic Targeting of Vascular Remodeling and Right Heart Failure in Pulmonary Arterial Hypertension with a HIF-2α Inhibitor |
| Q55286882 | Transient HIF2A inhibition promotes satellite cell proliferation and muscle regeneration. |
| Q36289608 | Tug of war in the haematopoietic stem cell niche: do myeloma plasma cells compete for the HSC niche? |
| Q38056889 | Understanding the hypoxic niche of multiple myeloma: therapeutic implications and contributions of mouse models. |
| Q39285839 | Vinorelbine inhibits angiogenesis and 95D migration via reducing hypoxic fibroblast stromal cell-derived factor 1 secretion |
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