Role of Esrrg in the fibrate-mediated regulation of lipid metabolism genes in human ApoA-I transgenic mice

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Role of Esrrg in the fibrate-mediated regulation of lipid metabolism genes in human ApoA-I transgenic mice is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1034405134
P356DOI10.1038/TPJ.2009.51
P932PMC publication ID2875298
P698PubMed publication ID19949424
P5875ResearchGate publication ID40042523

P2093author name stringV I Zannis
K C Hayes
D Sanoudou
A Duka
K Drosatos
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Peroxisome proliferator-activated receptor coactivator-1alpha (PGC-1alpha) coactivates the cardiac-enriched nuclear receptors estrogen-related receptor-alpha and -gamma. Identification of novel leucine-rich interaction motif within PGC-1alphaQ28218141
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Fibrates influence the expression of genes involved in lipoprotein metabolism in a tissue-selective manner in the ratQ28584207
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Fibrates downregulate apolipoprotein C-III expression independent of induction of peroxisomal acyl coenzyme A oxidase. A potential mechanism for the hypolipidemic action of fibratesQ34201490
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Mode of action of fibrates in the regulation of triglyceride and HDL-cholesterol metabolismQ36411159
The orphan nuclear receptor estrogen-related receptor alpha is a transcriptional regulator of the human medium-chain acyl coenzyme A dehydrogenase gene.Q36572042
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The transcriptional coactivator PGC-1 regulates the expression and activity of the orphan nuclear receptor estrogen-related receptor alpha (ERRalpha).Q40678460
PPARalpha and PPARgamma activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase geneQ41077493
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Pathway of biogenesis of apolipoprotein E-containing HDL in vivo with the participation of ABCA1 and LCAT.Q41902903
Up-regulation of pyruvate dehydrogenase kinase isoform 4 (PDK4) protein expression in oxidative skeletal muscle does not require the obligatory participation of peroxisome-proliferator-activated receptor alpha (PPARalpha).Q43002185
Apolipoprotein A-IV messenger ribonucleic acid abundance is regulated in a tissue-specific mannerQ43491947
Induction of the phospholipid transfer protein gene accounts for the high density lipoprotein enlargement in mice treated with fenofibrateQ43600867
Regulation of lipid metabolism and gene expression by fenofibrate in hamstersQ43814334
LDL receptor deficiency or apoE mutations prevent remnant clearance and induce hypertriglyceridemia in miceQ43916892
Amelioration of high fructose-induced metabolic derangements by activation of PPARalphaQ43948724
Identification of hepatic transcriptional changes in insulin-resistant rats treated with peroxisome proliferator activated receptor-alpha agonistsQ44468294
Liver gene expression in rats in response to the peroxisome proliferator-activated receptor-alpha agonist ciprofibrateQ44506981
Lecithin:cholesterol acyltransferase gene expression is regulated in a tissue-selective manner by fibrates.Q44979849
Targeted deletion of hepatic CTP:phosphocholine cytidylyltransferase alpha in mice decreases plasma high density and very low density lipoproteins.Q45032494
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Fenofibrate induces a novel degradation pathway for scavenger receptor B-I independent of PDZK1.Q46443680
Gene expression profiling of the PPAR-alpha agonist ciprofibrate in the cynomolgus monkey liverQ46635717
Transcriptional profile of postmortem skeletal muscleQ47377084
Expression of putative fatty acid transporter genes are regulated by peroxisome proliferator-activated receptor alpha and gamma activators in a tissue- and inducer-specific mannerQ47921885
Pharmacodynamic activity of lipoprotein lipase and hepatic lipase, and pharmacokinetic parameters measured in normolipidaemic subjects receiving ciprofibrate (100 or 200 mg/day) or micronised fenofibrate (200 mg/day) therapy for 23 days.Q51580711
Down-regulation of hepatic lipase gene expression and activity by fenofibrateQ52233138
Molecular profiles of inflammatory myopathies.Q54145481
Acyl-CoA synthetase mRNA expression is controlled by fibric-acid derivatives, feeding and liver proliferationQ57244405
Peroxisome proliferator-activated receptors gamma and alpha mediate in vivo regulation of uncoupling protein (UCP-1, UCP-2, UCP-3) gene expression.Q64942820
High levels of human apolipoprotein A-I in transgenic mice result in increased plasma levels of small high density lipoprotein (HDL) particles comparable to human HDL3Q69187299
Hormone-sensitive lipase and monoacylglycerol lipase are both required for complete degradation of adipocyte triacylglycerolQ70026539
Summary of the second report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II)Q70736889
A role for estrogen-related receptor alpha in the control of mitochondrial fatty acid beta-oxidation during brown adipocyte differentiationQ73935057
A hormone response element in the human apolipoprotein CIII (ApoCIII) enhancer is essential for intestinal expression of the ApoA-I and ApoCIII genes and contributes to the hepatic expression of the two linked genes in transgenic miceQ73993872
Beneficial effects of fibrates on apolipoprotein A-I metabolism occur independently of any peroxisome proliferative responseQ77726086
Tissue-specific effect of clofibrate on rat lipogenic enzyme gene expressionQ77766508
P433issue3
P304page(s)165-179
P577publication date2009-12-01
P1433published inThe Pharmacogenomics JournalQ10534704
P1476titleRole of Esrrg in the fibrate-mediated regulation of lipid metabolism genes in human ApoA-I transgenic mice
P478volume10

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