scholarly article | Q13442814 |
P50 | author | Bruce Spiegelman | Q21042408 |
Christopher B Newgard | Q87867408 | ||
P2093 | author name string | James Rhee | |
Pere Puigserver | |||
Ruojing Yang | |||
Jiandie Lin | |||
Paul T. Tarr | |||
P2860 | cites work | A tissue-specific coactivator of steroid receptors, identified in a functional genetic screen | Q22253330 |
Insulin signalling and the regulation of glucose and lipid metabolism | Q24292020 | ||
The PGC-1-related protein PERC is a selective coactivator of estrogen receptor alpha | Q24292329 | ||
Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator | Q24294798 | ||
Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting | Q24563197 | ||
The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression | Q24670887 | ||
A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis | Q27860471 | ||
Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1 | Q28131760 | ||
Peroxisome proliferator-activated receptor gamma coactivator 1beta (PGC-1beta ), a novel PGC-1-related transcription coactivator associated with host cell factor | Q28208668 | ||
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1 | Q28216275 | ||
Perturbation of fuel homeostasis caused by overexpression of the glucose-6-phosphatase catalytic subunit in liver of normal rats | Q28572235 | ||
Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres | Q29555845 | ||
CREB regulates hepatic gluconeogenesis through the coactivator PGC-1 | Q29615692 | ||
Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction | Q29619822 | ||
Regulation of glucose production by the liver | Q33711817 | ||
Mitochondrial DNA instability and peri-implantation lethality associated with targeted disruption of nuclear respiratory factor 1 in mice | Q33967022 | ||
Transcriptional regulation of liver development | Q34043393 | ||
New drug targets for type 2 diabetes and the metabolic syndrome | Q34105009 | ||
The orphan receptors COUP-TF and HNF-4 serve as accessory factors required for induction of phosphoenolpyruvate carboxykinase gene transcription by glucocorticoids | Q34763533 | ||
Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysis | Q35995063 | ||
Adenovirus-mediated transfer of low density lipoprotein receptor gene acutely accelerates cholesterol clearance in normal mice | Q36201407 | ||
Selection and analysis of galactose metabolic pathway variants of a mouse liver cell line | Q36723472 | ||
Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis | Q37526796 | ||
Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1alpha and PGC-1beta) in muscle cells | Q40649634 | ||
Cytokine stimulation of energy expenditure through p38 MAP kinase activation of PPARgamma coactivator-1. | Q40763964 | ||
Defect in peroxisome proliferator-activated receptor alpha-inducible fatty acid oxidation determines the severity of hepatic steatosis in response to fasting. | Q51555809 | ||
P433 | issue | 33 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | glucose | Q37525 |
P304 | page(s) | 30843–30848 | |
P577 | publication date | 2003-08-15 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | PGC-1beta in the regulation of hepatic glucose and energy metabolism | |
P478 | volume | 278 |
Q30497916 | A reduction in ATP demand and mitochondrial activity with neural differentiation of human embryonic stem cells. |
Q27335066 | Ablation of PGC-1beta results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance |
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