| Q74464460 | 'Loop' domain deletional mutant of Bcl-xL is as effective as p29Bcl-xL in inhibiting radiation-induced cytosolic accumulation of cytochrome c (cyt c), caspase-3 activity, and apoptosis |
| Q43769936 | 17-beta-estradiol alters Jurkat lymphocyte cell cycling and induces apoptosis through suppression of Bcl-2 and cyclin A. |
| Q63408384 | A matter of life and death |
| Q81358761 | A mismatched role for Bcl-2 |
| Q27649579 | A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation |
| Q39644466 | A novel role for the Bcl-2 protein family: specific suppression of the RAD51 recombination pathway |
| Q40489962 | A proteolytic fragment of Mcl-1 exhibits nuclear localization and regulates cell growth by interaction with Cdk1. |
| Q42855863 | A survivor hits the breaks |
| Q36611899 | Absence of Bcl-2 and Fas/CD95/APO-1 predicts the response to immunotherapy in metastatic renal cell carcinoma |
| Q35879720 | Acquisition of apoptotic resistance in cadmium-transformed human prostate epithelial cells: Bcl-2 overexpression blocks the activation of JNK signal transduction pathway |
| Q37251275 | Activation of NQO1 in NQO1*2 polymorphic human leukemic HL-60 cells by diet-derived sulforaphane |
| Q28477722 | Activation of multiple apoptotic pathways in human nasopharyngeal carcinoma cells by the prenylated isoflavone, osajin |
| Q36847519 | Affinity purification-mass spectrometry analysis of bcl-2 interactome identified SLIRP as a novel interacting protein. |
| Q27469588 | Antiapoptotic but not antiviral function of human bcl-2 assists establishment of Japanese encephalitis virus persistence in cultured cells |
| Q33787044 | Antiapoptotic herpesvirus Bcl-2 homologs escape caspase-mediated conversion to proapoptotic proteins |
| Q33923835 | Apoptosis and cell division |
| Q74425511 | Apoptosis and cell-cycle regulatory proteins in colorectal carcinoma: relationship to tumour stage and patient survival |
| Q36194530 | Apoptosis and immaturity in acute myeloid leukemia |
| Q39918140 | Apoptosis and its suppression in hepatocytes culture |
| Q36960721 | Apoptosis is triggered when prosurvival Bcl-2 proteins cannot restrain Bax. |
| Q34395580 | Apoptosis regulators and their role in tumorigenesis |
| Q28211754 | BAD/BCL-[X(L)] heterodimerization leads to bypass of G0/G1 arrest |
| Q44422869 | BCL-2 and BCL-XL restrict lineage choice during hematopoietic differentiation |
| Q35006788 | BCL-2 family protein, BAD is down-regulated in breast cancer and inhibits cell invasion |
| Q40691704 | BCL-x(L) and BCL2 delay Myc-induced cell cycle entry through elevation of p27 and inhibition of G1 cyclin-dependent kinases |
| Q36501194 | BCL2 family in DNA damage and cell cycle control |
| Q51777155 | BCL2L12A localizes to the cell nucleus and induces growth inhibition through G2/M arrest in CHO cells. |
| Q40092563 | BRE is an antiapoptotic protein in vivo and overexpressed in human hepatocellular carcinoma. |
| Q55475811 | Bag-1 and Bcl-2 gene transfer in malignant glioma: modulation of cell cycle regulation and apoptosis. |
| Q51811083 | Bax and Bid, two proapoptotic Bcl-2 family members, inhibit homologous recombination, independently of apoptosis regulation. |
| Q42524349 | Bax expression and growth behavior of basal cell carcinomas |
| Q34735853 | Bcl-2 Gene Family in Endocrine Pathology: A Review |
| Q73694637 | Bcl-2 and Bax proteins are present in interphase nuclei of mammalian cells |
| Q42667002 | Bcl-2 blocks 2-methoxyestradiol induced leukemia cell apoptosis by a p27(Kip1)-dependent G1/S cell cycle arrest in conjunction with NF-kappaB activation |
| Q40417967 | Bcl-2 decreases cell proliferation and promotes accumulation of cells in S phase without affecting the rate of apoptosis in human ovarian carcinoma cells |
| Q77769534 | Bcl-2 expression delays hepatocyte cell cycle progression during liver regeneration |
| Q35748053 | Bcl-2 expression inhibits liver carcinogenesis and delays the development of proliferating foci |
| Q28300063 | Bcl-2 expression suppresses mismatch repair activity through inhibition of E2F transcriptional activity |
| Q36429868 | Bcl-2 family members do not inhibit apoptosis by binding the caspase activator Apaf-1 |
| Q33699417 | Bcl-2 gene family and related proteins in mammary gland involution and breast cancer |
| Q31407508 | Bcl-2 independence of flavopiridol-induced apoptosis. Mitochondrial depolarization in the absence of cytochrome c release. |
| Q43516172 | Bcl-2 inhibits apoptosis of spermatogonia and growth of spermatogonial stem cells in a cell-intrinsic manner |
| Q40769247 | Bcl-2 is an apoptotic target suppressed by both c-Myc and E2F-1. |
| Q40943450 | Bcl-2 over-expression reduces growth rate and prolongs G1 phase in continuous chemostat cultures of hybridoma cells |
| Q40659371 | Bcl-2 promotes premature senescence induced by oncogenic Ras. |
| Q33964373 | Bcl-2 retards cell cycle entry through p27(Kip1), pRB relative p130, and altered E2F regulation |
| Q52533610 | Bcl-xL and Bcl-2 expression in squamous cell carcinoma of the head and neck. |
| Q39962406 | Bcl-xL/Bcl-2 coordinately regulates apoptosis, cell cycle arrest and cell cycle entry |
| Q28511847 | Bim regulates BCR-induced entry of B cells into the cell cycle |
| Q24532974 | Bim: a novel member of the Bcl-2 family that promotes apoptosis |
| Q43140152 | Biologically distinct conformations of Bcl-x can be resolved using 2D isoelectric focusing |
| Q42266182 | Blocking the mitochondrial apoptotic pathway preserves motor neuron viability and function in a mouse model of amyotrophic lateral sclerosis |
| Q22010049 | Btf, a novel death-promoting transcriptional repressor that interacts with Bcl-2-related proteins |
| Q35160263 | Buffy, a Drosophila Bcl-2 protein, has anti-apoptotic and cell cycle inhibitory functions |
| Q57274132 | Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9 |
| Q34207528 | Caspases: more than just killers? |
| Q57375673 | Caveolin-1: a complex and provocative therapeutic target in prostate cancer and potentially other malignancies |
| Q37079878 | Chemoresistance in gliomas |
| Q40820011 | Comparison of Bcl-2 to a Bcl-2 deletion mutant for mammalian cells exposed to culture insults |
| Q36776853 | Constitutive Bcl-2 expression throughout the hematopoietic compartment affects multiple lineages and enhances progenitor cell survival |
| Q22008570 | Control of apoptosis and mitotic spindle checkpoint by survivin |
| Q34170806 | Control of apoptosis in hematopoietic cells by the Bcl-2 family of proteins |
| Q28142562 | Cyclin' on the viral path to destruction |
| Q42451048 | DNA synthesis and Bcl-2 expression during development of mucous cell metaplasia in airway epithelium of rats exposed to LPS. |
| Q35815150 | DNA-damage response network at the crossroads of cell-cycle checkpoints, cellular senescence and apoptosis |
| Q36316368 | Debcl, a proapoptotic Bcl-2 homologue, is a component of the Drosophila melanogaster cell death machinery. |
| Q57272593 | Dependence of granzyme B-mediated cell death on a pathway regulated by Bcl-2 or its viral homolog, BHRF1 |
| Q73763477 | Differential clonal expansion of CD4 and CD8 T cells in response to 4-1BB ligation: contribution of 4-1BB during inflammatory responses |
| Q47886310 | Dismantling in cell death: molecular mechanisms and relationship to caspase activation |
| Q34135695 | Dissecting p53 tumor suppressor functions in vivo |
| Q34091244 | Diva/Boo is a negative regulator of cell death in human glioma cells |
| Q46346438 | Drosophila Bcl-2 proteins participate in stress-induced apoptosis, but are not required for normal development |
| Q36072488 | Dynamic Bcl-xL (S49) and (S62) Phosphorylation/Dephosphorylation during Mitosis Prevents Chromosome Instability and Aneuploidy in Normal Human Diploid Fibroblasts |
| Q46529662 | EGL-1 BH3 mutants reveal the importance of protein levels and target affinity for cell-killing potency. |
| Q36375602 | Early activation of caspases during T lymphocyte stimulation results in selective substrate cleavage in nonapoptotic cells |
| Q73347777 | Ectopic expression of Bcl-2 switches over nuclear signalling for cAMP-induced apoptosis to granulocytic differentiation |
| Q77589893 | Effect of Bcl-2 expression on hepatic preneoplasia in mice |
| Q34369809 | Elevated Mcl-1 perturbs lymphopoiesis, promotes transformation of hematopoietic stem/progenitor cells, and enhances drug resistance |
| Q35032627 | Enforced expression of the apoptosis inhibitor Bcl-2 ablates tolerance induction in DNA-reactive B cells through a novel mechanism |
| Q40641095 | Estrogen and progesterone modulate monocyte cell cycle progression and apoptosis |
| Q33965788 | Estrogenic activity of coumestrol, DDT, and TCDD in human cervical cancer cells |
| Q74372236 | Expression of Bax and apoptosis-related proteins in human esophageal squamous cell carcinoma including dysplasia |
| Q77697362 | Expression of Bcl-2, Bcl-x, Mcl-1, Bax and Bak in human uterine leiomyomas and myometrium during the menstrual cycle and after menopause |
| Q81149836 | Expression of PCNA, p53, Bax, and Bcl-X in oral poorly differentiated and basaloid squamous cell carcinoma: relationships with prognosis |
| Q53664165 | Expression of cell cycle regulatory proteins in ovaries prophylactically removed from Jewish Ashkenazi BRCA1 and BRCA2 mutation carriers: correlation with histopathology. |
| Q43874623 | Expression of survivin, Bcl-2 and Bax proteins in the domestic cat (Felis catus) endometrium during the oestrus cycle |
| Q37880074 | From cell biology to therapy: ENMD-2076 in the treatment of multiple myeloma |
| Q30839663 | Functional cloning of SPIN-2, a nuclear anti-apoptotic protein with roles in cell cycle progression |
| Q39582084 | Functional differences between BHRF1, the Epstein-Barr virus-encoded Bcl-2 homologue, and Bcl-2 in human epithelial cells |
| Q49720385 | Genetic variants in IL15 promoter affect transcription activity and intramuscular fat deposition in longissimus dorsi muscle of pigs |
| Q34055787 | Herpesvirus homologues of cellular genes |
| Q38313948 | Identification of an ataxia telangiectasia-mutated protein mediated surveillance system to regulate Bcl-2 overexpression |
| Q47073853 | Imbalance in liver homeostasis leading to hyperplasia by overexpressing either one of the Bcl-2-related genes, zfBLP1 and zfMcl-1a |
| Q54690940 | Immunohistochemical detection of Ki67 in breast cancer correlates with transcriptional regulation of genes related to apoptosis and cell death. |
| Q36292668 | Immunohistochemical detection of p53 and Bcl-2 in colorectal carcinoma: no evidence for prognostic significance |
| Q80527467 | In situ localization of apoptotic changes in the interface membrane of aseptically loosened orthopaedic implants |
| Q33921263 | In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability |
| Q39918016 | Influence of bcl-2 on antibody productivity in high cell density perfusion cultures of hybridoma |
| Q40896291 | Influence of bcl-2 on cell death during the cultivation of a Chinese hamster ovary cell line expressing a chimeric antibody. |
| Q36368577 | Initiation of apoptosis by granzyme B requires direct cleavage of bid, but not direct granzyme B-mediated caspase activation. |
| Q74416103 | Interleukin-2-mediated survival and proliferative signals are uncoupled in T lymphocytes that fail to divide after activation |
| Q40984598 | Interleukin-3 induces the phosphorylation of a distinct fraction of bcl-2. |
| Q40653567 | Life span shortening of normal fibroblasts by overexpression of BCL-2: a result of potent increase in cell death |
| Q41773989 | Ligand activated progesterone receptor B drives autophagy-senescence transition through a Beclin-1/Bcl-2 dependent mechanism in human breast cancer cells |
| Q24537892 | Linking sister chromatid cohesion and apoptosis: role of Rad21. |
| Q38440406 | Loss of BCL-2 in the progression of oral cancer is not attributable to mutations |
| Q36136644 | Loss of Bim results in abnormal accumulation of mature CD4-CD8-CD44-CD25- thymocytes |
| Q73270773 | Loss of anti-mitotic effects of Bcl-2 with retention of anti-apoptotic activity during tumor progression in a mouse model |
| Q36691973 | Low expression of bcl-2 in Brca1-associated breast cancers |
| Q47895480 | Lymphoma development in Bax transgenic mice is inhibited by Bcl-2 and associated with chromosomal instability. |
| Q48027266 | Matters of life and death: programmed cell death at Cold Spring Harbor |
| Q52826978 | Mcl-1 and Bcl-xL are co-regulated by IL-6 in human myeloma cells. |
| Q43002647 | Mechanism of action of interleukin-2 (IL-2)-Bax, an apoptosis-inducing chimaeric protein targeted against cells expressing the IL-2 receptor |
| Q34040608 | Mimicking pregnancy as a strategy for breast cancer prevention. |
| Q59009610 | Mitochondria shape up |
| Q77709638 | Moderate activation of the apoptosis inhibitor bcl-xL worsens the prognosis in pancreatic cancer |
| Q28513666 | Mono- and multisite phosphorylation enhances Bcl2's antiapoptotic function and inhibition of cell cycle entry functions |
| Q34276988 | Mutations in apoptosis genes: a pathogenetic factor for human disease |
| Q38753660 | Non-apoptotic functions of BCL-2 family proteins |
| Q35874918 | Non-apoptotic functions of apoptosis-regulatory proteins |
| Q38756877 | Non-canonical roles of Bcl-2 and Bcl-xL proteins: relevance of BH4 domain |
| Q33502518 | Novel Bcl-2 homology-3 domain-like sequences identified from screening randomized peptide libraries for inhibitors of the pro-survival Bcl-2 proteins. |
| Q38999607 | Obatoclax induces G1/G0-phase arrest via p38/p21(waf1/Cip1) signaling pathway in human esophageal cancer cells |
| Q41959713 | Phospho-Bcl-x(L)(Ser62) plays a key role at DNA damage-induced G(2) checkpoint |
| Q44052586 | Phosphorylation of Bcl-2 in G2/M phase-arrested cells following photodynamic therapy with hypericin involves a CDK1-mediated signal and delays the onset of apoptosis. |
| Q73680430 | Phosphorylation of Bcl-2 protein by CDC2 kinase during G2/M phases and its role in cell cycle regulation |
| Q30865931 | Pro-apoptotic apoptosis protease-activating factor 1 (Apaf-1) has a cytoplasmic localization distinct from Bcl-2 or Bcl-x(L). |
| Q24675444 | Proapoptotic BH3-only proteins trigger membrane integration of prosurvival Bcl-w and neutralize its activity |
| Q41129712 | Prognostic value of Bcl-2 in breast cancer patients treated with neoadjuvant anthracycline based chemotherapy. |
| Q30492978 | Proliferation control strategies to improve productivity and survival during CHO based production culture : A summary of recent methods employed and the effects of proliferation control in product secreting CHO cell lines |
| Q40670642 | R-Ras alters Ca2+ homeostasis by increasing the Ca2+ leak across the endoplasmic reticular membrane. |
| Q35189463 | Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis |
| Q36670905 | Removal of the BH4 domain from Bcl-2 protein triggers an autophagic process that impairs tumor growth |
| Q35192102 | Role of Nr13 in regulation of programmed cell death in the bursa of Fabricius |
| Q47192395 | Role of β-Interferon Inducer (DEAE-Dextran) in Tumorigenesis by VEGF and NOTCH1 Inhibition along with Apoptosis Induction |
| Q40853948 | Schizosaccharomyces pombe Rad9 contains a BH3-like region and interacts with the anti-apoptotic protein Bcl-2. |
| Q77803743 | Seeking muscle stem cells |
| Q34780573 | Sensory neuropathy attributable to loss of Bcl-w |
| Q36363353 | Sheeppox virus SPPV14 encodes a Bcl-2-like cell death inhibitor that counters a distinct set of mammalian proapoptotic proteins. |
| Q60370453 | Somatic Hypermutation of Ig Genes is Affected Differently by Failures in Apoptosis Caused by Disruption of Fas (lpr Mutation) or by Overexpression of Bcl-2 |
| Q44117862 | Stromal cells prevent apoptosis of AML cells by up-regulation of anti-apoptotic proteins |
| Q27666435 | Structural Basis for Apoptosis Inhibition by Epstein-Barr Virus BHRF1 |
| Q57067509 | Sunset Yellow and Allura Red modulate Bcl2 and COX2 expression levels and confer oxidative stress-mediated renal and hepatic toxicity in male rats |
| Q42064781 | The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized. |
| Q35591695 | The Bcl-2 family: roles in cell survival and oncogenesis. |
| Q35031256 | The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions |
| Q95721798 | The Chk1-Cdc25C regulation is involved in sensitizing A253 cells to a novel topoisomerase I inhibitor BNP1350 by bax gene transfer |
| Q44078274 | The anti-apoptotic genes Bcl-X(L) and Bcl-2 are over-expressed and contribute to chemoresistance of non-proliferating leukaemic CD34+ cells |
| Q34474341 | The basic helix-loop-helix transcription factor Nex-1/Math-2 promotes neuronal survival of PC12 cells by modulating the dynamic expression of anti-apoptotic and cell cycle regulators. |
| Q34662848 | The configuration of the immunoglobulin genes in B cell chronic lymphocytic leukemia |
| Q24309225 | The conserved N-terminal BH4 domain of Bcl-2 homologues is essential for inhibition of apoptosis and interaction with CED-4 |
| Q44718490 | The presence of 19-kDa Bcl-2 in dividing cells |
| Q36301514 | The pro-apoptotic proteins, Bid and Bax, cause a limited permeabilization of the mitochondrial outer membrane that is enhanced by cytosol |
| Q35745742 | The proapoptotic BH3-only protein bim is expressed in hematopoietic, epithelial, neuronal, and germ cells |
| Q39677796 | The retinoblastoma protein binds the promoter of the survival gene bcl-2 and regulates its transcription in epithelial cells through transcription factor AP-2. |
| Q26851645 | The role of Bcl-2 family proteins in therapy responses of malignant astrocytic gliomas: Bcl2L12 and beyond |
| Q34242701 | The role of apoptosis in regulating hematopoiesis and hematopoietic stem cells |
| Q44297006 | The role of various Bcl-2 domains in the anti-proliferative effect and modulation of cellular glutathione levels: a prominent role for the BH4 domain |
| Q28203506 | Tissue expression and subcellular localization of the pro-survival molecule Bcl-w |
| Q37140322 | Transgenic Bcl-3 slows T cell proliferation |
| Q28592731 | Transgenic models of lymphoid neoplasia and development of a pan-hematopoietic vector |
| Q39433259 | miR-125b and miR-155 contribute to BCL2 repression and proliferation in response to CD40 ligand (CD154) in human leukemic B-cells |
| Q33326639 | p27 deficiency cooperates with Bcl-2 but not Bax to promote T-cell lymphoma. |