The essential functions of NEDD8 are mediated via distinct surface regions, and not by polyneddylation in Schizosaccharomyces pombe

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The essential functions of NEDD8 are mediated via distinct surface regions, and not by polyneddylation in Schizosaccharomyces pombe is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2011PLoSO...620089G
P356DOI10.1371/JOURNAL.PONE.0020089
P932PMC publication ID3105002
P698PubMed publication ID21655279
P5875ResearchGate publication ID51203340

P2093author name stringDimitris P Xirodimas
Colin Gordon
David Girdwood
P2860cites workThe conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiaeQ24306410
Regulation of nucleolar signalling to p53 through NEDDylation of L11Q24310534
Ribosomal proteins are targets for the NEDD8 pathwayQ24313502
Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugationQ24314520
A new NEDD8-ligating system for cullin-4AQ24321773
NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligasesQ24337709
Structural basis of NEDD8 ubiquitin discrimination by the deNEDDylating enzyme NEDP1.Q24529121
Direct interactions between NEDD8 and ubiquitin E2 conjugating enzymes upregulate cullin-based E3 ligase activity.Q51088435
Three novel antibiotic marker cassettes for gene disruption and marker switching in Schizosaccharomyces pombe.Q52566419
The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1Q27642844
Structure of ubiquitin refined at 1.8 A resolutionQ27728512
Structure of tetraubiquitin shows how multiubiquitin chains can be formedQ27730945
Crystal structure of the human ubiquitin-like protein NEDD8 and interactions with ubiquitin pathway enzymesQ27766356
Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1.Q27931858
Cullin neddylation and substrate-adaptors counteract SCF inhibition by the CAND1-like protein Lag2 in Saccharomyces cerevisiae.Q27932725
Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chainQ28142613
The Nedd8-conjugated ROC1-CUL1 core ubiquitin ligase utilizes Nedd8 charged surface residues for efficient polyubiquitin chain assembly catalyzed by Cdc34Q28201996
NEDP1, a highly conserved cysteine protease that deNEDDylates CullinsQ28202321
DEN1 is a dual function protease capable of processing the C terminus of Nedd8 and deconjugating hyper-neddylated CUL1Q28205415
Modification of proteins by ubiquitin and ubiquitin-like proteinsQ28244250
Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activityQ28270986
Structure of a complex between Nedd8 and the Ulp/Senp protease family member Den1Q28295412
Molecular genetic analysis of fission yeast Schizosaccharomyces pombeQ29547703
Ubiquitin-binding domainsQ29614358
Ubiquitin-binding domains - from structures to functionsQ29614829
Ubiquitin and ubiquitin-like proteins as multifunctional signalsQ30014838
Surface hydrophobic residues of multiubiquitin chains essential for proteolytic targetingQ33292109
Novel substrates and functions for the ubiquitin-like molecule NEDD8.Q34827554
Autoinhibitory regulation of SCF-mediated ubiquitination by human cullin 1's C-terminal tailQ36844169
Multimodal activation of the ubiquitin ligase SCF by Nedd8 conjugationQ37101488
A targeted proteomic analysis of the ubiquitin-like modifier nedd8 and associated proteins.Q37178794
The diversity of ubiquitin recognition: hot spots and varied specificityQ37764527
Characterization of Schizosaccharomyces pombe Hus1: a PCNA-related protein that associates with Rad1 and Rad9Q39450987
A ubiquitin mutant with specific defects in DNA repair and multiubiquitinationQ40015739
Covalent modifier NEDD8 is essential for SCF ubiquitin-ligase in fission yeastQ40430046
Nedd8-modification of Cul1 is promoted by Roc1 as a Nedd8-E3 ligase and regulates its stabilityQ40673171
Cell cycle-regulated modification of the ribosome by a variant multiubiquitin chainQ40863875
Ubiquitin lys63 is involved in ubiquitination of a yeast plasma membrane proteinQ42174399
In vitro assembly and recognition of Lys-63 polyubiquitin chainsQ43615489
Distinct functional surface regions on ubiquitinQ43635274
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectSchizosaccharomyces pombeQ2236682
P304page(s)e20089
P577publication date2011-05-31
P1433published inPLOS OneQ564954
P1476titleThe essential functions of NEDD8 are mediated via distinct surface regions, and not by polyneddylation in Schizosaccharomyces pombe
P478volume6

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cites work (P2860)
Q36271570A high throughput mutagenic analysis of yeast sumo structure and function.
Q34621887Nedd8 processing enzymes in Schizosaccharomyces pombe
Q34793372Phage display to identify Nedd8-mimicking peptides as inhibitors of the Nedd8 transfer cascade
Q34042816Protein neddylation: beyond cullin-RING ligases
Q21129204The NEDD8 modification pathway in plants
Q28087342Ubiquitylation, neddylation and the DNA damage response

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