p38 MAP kinases: beyond the stress response

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p38 MAP kinases: beyond the stress response is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S0968-0004(00)01595-4
P698PubMed publication ID10838561

P50authorAlmudena PorrasQ60316553
P2093author name stringNebreda AR
Porras A
P2860cites workNeuronal activity-dependent cell survival mediated by transcription factor MEF2Q28146016
Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP KinaseQ28280649
MEF2 is upregulated during cardiac hypertrophy and is required for normal post-natal growth of the myocardiumQ28506129
Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell deathQ28570235
p38 mitogen-activated protein kinase pathway promotes skeletal muscle differentiation. Participation of the Mef2c transcription factorQ28646220
p38 mitogen-activated protein kinase functionally contributes to chondrogenesis induced by growth/differentiation factor-5 in ATDC5 cellsQ33178681
Cardiac hypertrophy: sorting out the circuitryQ33665828
The Drosophila p38 MAPK pathway is required during oogenesis for egg asymmetric development.Q33864479
p38 mitogen-activated protein kinase can be involved in transforming growth factor beta superfamily signal transduction in Drosophila wing morphogenesisQ33957563
Cell cycle arrest and reversion of Ras-induced transformation by a conditionally activated form of mitogen-activated protein kinase kinase kinase 3.Q33958377
Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase familyQ34453631
Use of a drug-resistant mutant of stress-activated protein kinase 2a/p38 to validate the in vivo specificity of SB 203580.Q40947866
Stress-activated protein kinase-2/p38 and a rapamycin-sensitive pathway are required for C2C12 myogenesisQ40975177
Cooperation of p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways during granulocyte colony-stimulating factor-induced hemopoietic cell proliferationQ40975219
Specific inhibitors of p38 mitogen-activated protein kinase block 3T3-L1 adipogenesisQ40993756
Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway.Q41173912
An inhibitor of p38 mitogen-activated protein kinase protects neonatal cardiac myocytes from ischemiaQ41609637
p38 mitogen-activated protein kinase activation is required for fibroblast growth factor-2-stimulated cell proliferation but not differentiationQ41671454
Requirement of p38 mitogen-activated protein kinase for neuronal differentiation in PC12 cellsQ42539781
Cdc42Hs, but not Rac1, inhibits serum-stimulated cell cycle progression at G1/S through a mechanism requiring p38/RK.Q42800747
Constitutively active mitogen-activated protein kinase kinase 6 (MKK6) or salicylate induces spontaneous 3T3-L1 adipogenesisQ42808012
MKK6 activates myocardial cell NF-kappaB and inhibits apoptosis in a p38 mitogen-activated protein kinase-dependent mannerQ44160668
Induction of apoptosis by SB202190 through inhibition of p38beta mitogen-activated protein kinaseQ47954457
Targeted down-regulation of caveolin-3 is sufficient to inhibit myotube formation in differentiating C2C12 myoblasts. Transient activation of p38 mitogen-activated protein kinase is required for induction of caveolin-3 expression and subsequent myotQ73066721
Specific activation of the p38 mitogen-activated protein kinase signaling pathway and induction of neurite outgrowth in PC12 cells by bone morphogenetic protein-2Q78208149
P433issue6
P407language of work or nameEnglishQ1860
P1104number of pages4
P304page(s)257-260
P577publication date2000-06-01
P1433published inTrends in Biochemical SciencesQ1565711
P1476titlep38 MAP kinases: beyond the stress response
P478volume25

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cites work (P2860)
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Q49747284Decreased expression of the long non-coding RNA SLC7A11-AS1 predicts poor prognosis and promotes tumor growth in gastric cancer
Q42654343Defatting of acetone leaf extract of Acacia karroo (Hayne) enhances its hypoglycaemic potential.
Q44224221Delta MEKK3:ER* activation induces a p38 alpha/beta 2-dependent cell cycle arrest at the G2 checkpoint
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Q42093335Differential involvement of p38 mitogen-activated protein kinase kinases MKK3 and MKK6 in T-cell apoptosis
Q34336416Differentiation, apoptosis, and function of human immature and mature myeloid cells: intracellular signaling mechanism
Q41952858Dihydroberberine exhibits synergistic effects with sunitinib on NSCLC NCI-H460 cells by repressing MAP kinase pathways and inflammatory mediators
Q39647867Diphenyl diselenide induces apoptotic cell death and modulates ERK1/2 phosphorylation in human neuroblastoma SH-SY5Y cells
Q36002854Distinct cardiodynamic and molecular characteristics during early and late stages of sepsis-induced myocardial dysfunction
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Q37682247Downregulation of MMP1 in MDS-derived mesenchymal stromal cells reduces the capacity to restrict MDS cell proliferation
Q42509418EGF-R regulates MMP function in fibroblasts through MAPK and AP-1 pathways.
Q39091777ERK pathway is activated in bare-FeNPs-induced autophagy
Q46487836ERK1/2 and p38 regulate trophoblasts differentiation in human term placenta.
Q36953314Effect of Helicobacter pylori on NFKB1, p38α and TNF-α mRNA expression levels in human gastric mucosa
Q35815140Effect of lead on ERK activity and the protective function of bFGF in rat primary culture astroglia
Q35109743Effect of p38 MAP kinases on contractility and ischemic injury in intact heart
Q46966257Effect of retinoic acid on cell proliferation and differentiation as well as on lipid synthesis, lipoprotein secretion, and apolipoprotein biogenesis
Q36444286Effects of calcium-sensing receptor on the secretion of parathyroid hormone-related peptide and its impact on humoral hypercalcemia of malignancy.
Q37726491Effects of p38α/β inhibition on acute lymphoblastic leukemia proliferation and survival in vivo
Q90471586Enhancement of Macrophage Function by the Antimicrobial Peptide Sublancin Protects Mice from Methicillin-Resistant Staphylococcus aureus
Q40602773Epigallocatechin-3-gallate inhibits epidermal growth factor receptor signaling pathway. Evidence for direct inhibition of ERK1/2 and AKT kinases.
Q35054708Epithelial cell senescence impairs repair process and exacerbates inflammation after airway injury
Q47136971Essential role of mitochondrial Stat3 in p38MAPK mediated apoptosis under oxidative stress.
Q46037321Essential role of p38 MAPK in caspase-independent, iPLA(2)-dependent cell death under hypoxia/low glucose conditions.
Q40430785Essential role of p38gamma in K-Ras transformation independent of phosphorylation
Q42438492Eukaryotic elongation factor 2 controls TNF-α translation in LPS-induced hepatitis
Q39988758Examination of the cellular mechanisms by which marinobufagenin inhibits cytotrophoblast function
Q34451539Expression and activation of mitogen-activated protein kinases in matured porcine oocytes under thermal stress.
Q47448061Expression of Oryza sativa MAP kinase gene is developmentally regulated and stress-responsive
Q24531403Extracellular signal-regulated kinase phosphorylates tumor necrosis factor alpha-converting enzyme at threonine 735: a potential role in regulated shedding.
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Q53173608From oncogene to tumor suppressor: the dual role of Myc in leukemia.
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Q39891313Generation and characterization of p38beta (MAPK11) gene-targeted mice.
Q35672032Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38alpha in abrogating myoblast proliferation
Q37295316Genetic variants of GADD45A, GADD45B and MAPK14 predict platinum-based chemotherapy-induced toxicities in Chinese patients with non-small cell lung cancer
Q40468889Genetic variants of JNK and p38α pathways and risk of non-small cell lung cancer in an Eastern Chinese population.
Q52654188Genome-wide survey of protein kinases required for cell cycle progression.
Q34467934HOG on the promoter: regulation of the osmotic stress response
Q39785077Heparin regulates colon cancer cell growth through p38 mitogen-activated protein kinase signalling
Q39684768Hepatitis B virus X protein activates the p38 mitogen-activated protein kinase pathway in dedifferentiated hepatocytes
Q38760084Hepatocyte growth factor and alternative splice variants - expression, regulation and implications in osteogenesis and bone health and repair
Q90641455Hepatospecific ablation of p38α MAPK governs liver regeneration through modulation of inflammatory response to CCl4-induced acute injury
Q33916318Hormesis effects of silver nanoparticles at non-cytotoxic doses to human hepatoma cells
Q57059658Hsp70 interacts with MAPK-activated protein kinase 2 to regulate p38MAPK stability and myoblast differentiation during skeletal muscle regeneration
Q34579680Hyperactive variants of p38alpha induce, whereas hyperactive variants of p38gamma suppress, activating protein 1-mediated transcription
Q34804514IL-6 activates serum and glucocorticoid kinase via p38alpha mitogen-activated protein kinase pathway
Q35250612In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer.
Q28505561Inactivation of Rheb by PRAK-mediated phosphorylation is essential for energy-depletion-induced suppression of mTORC1
Q51999206Induction of apoptosis and cellular senescence in mice lacking transcription elongation factor, Elongin A.
Q43832936Inhibition of PI3K/p70 S6K and p38 MAPK cascades increases osteoblastic differentiation induced by BMP-2.
Q39824870Inhibition of basal p38 or JNK activity enhances epithelial barrier function through differential modulation of claudin expression
Q37557188Inhibition of phosphodiesterase-4 promotes oligodendrocyte precursor cell differentiation and enhances CNS remyelination.
Q42842968Inhibition of tumor promoting signals by activation of SSTR2 and opioid receptors in human breast cancer cells
Q38832198Insulin-like growth factor 1 receptor and p38 mitogen-activated protein kinase signals inversely regulate signal transducer and activator of transcription 3 activity to control human dental pulp stem cell quiescence, propagation, and differentiation
Q34377183Integrating stress-response and cell-cycle checkpoint pathways
Q81333268Interferon-beta protects astrocytes against tumour necrosis factor-induced apoptosis via activation of p38 mitogen-activated protein kinase
Q39024648Interleukin-1 stimulates glutamate uptake in glial cells by accelerating membrane trafficking of Na+/K+-ATPase via actin depolymerization
Q40815583Intestinal epithelial cell differentiation involves activation of p38 mitogen-activated protein kinase that regulates the homeobox transcription factor CDX2.
Q36405454Involvement of the p38 MAPK-NF-kappaB signal transduction pathway and COX-2 in the pathobiology of meniscus degeneration in humans
Q33569707Ionizing radiation induces cellular senescence of articular chondrocytes via negative regulation of SIRT1 by p38 kinase
Q44282483Irisin and FNDC5: effects of 12-week strength training, and relations to muscle phenotype and body mass composition in untrained women
Q24540351JLP: A scaffolding protein that tethers JNK/p38MAPK signaling modules and transcription factors.
Q24674569Japanese encephalitis virus infection initiates endoplasmic reticulum stress and an unfolded protein response
Q33796903L-Carnitine rescues ketamine-induced attenuated heart rate and MAPK (ERK) activity in zebrafish embryos
Q92216284Lic regulates JNK-mediated cell death in Drosophila
Q42826277Long-term potentiation of wound-induced exocytosis and plasma membrane repair is dependent on cAMP-response element-mediated transcription via a protein kinase C- and p38 MAPK-dependent pathway
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Q33705505MAP kinase p38 is a novel target of CacyBP/SIP phosphatase
Q35575324MAP kinases in chondrocyte differentiation.
Q39870546MAP kinases in proliferating human colon cancer Caco-2 cells
Q37508518MAPK signaling pathways in the regulation of hematopoiesis
Q40224907MAPK-activated protein kinase-2 (MK2)-mediated formation and phosphorylation-regulated dissociation of the signal complex consisting of p38, MK2, Akt, and Hsp27.
Q64120396MEF-2 isoforms' (A-D) roles in development and tumorigenesis
Q40081397MKK6 phosphorylation regulates production of superoxide by enhancing Rac GTPase activity
Q37217986Marinobufagenin causes endothelial cell monolayer hyperpermeability by altering apoptotic signaling
Q35756940Maternal Nanos represses hid/skl-dependent apoptosis to maintain the germ line in Drosophila embryos
Q39955500Mechanism(s) Involved in Carbon Monoxide-releasing Molecule-2-mediated Cardioprotection During Ischaemia-reperfusion Injury in Isolated Rat Heart.
Q37000710Mitochondrial permeabilization without caspase activation mediates the increase of basal apoptosis in cells lacking Nrf2.
Q34473609Mitogen-activated protein kinase (MAPK)-docking sites in MAPK kinases function as tethers that are crucial for MAPK regulation in vivo
Q42979531Mitogen-activated protein kinase activated protein kinase 2 (MK2) participates in p38 MAPK regulated control of oligodendrocyte differentiation
Q40740565Mitogen-activated protein kinase-dependent and -independent routes control shedding of transmembrane growth factors through multiple secretases.
Q31004055Mitogen-activated protein kinases, adherens junction dynamics, and spermatogenesis: a review of recent data
Q40492947Modulation of the p38 MAPK (mitogen-activated protein kinase) pathway through Bcr/Abl: implications in the cellular response to Ara-C.
Q54215670Molecular Cloning and Expression Determination of p38 MAPK from the Liver and Kidney of Silver Carp.
Q60303251Molecular mechanism by which MKK6 ()-mediated MAPK cascades regulate the oxidative stress response
Q94475934Morusin exerts anti-cancer activity in renal cell carcinoma by disturbing MAPK signaling pathways
Q41767222Mouse embryonic stem cells lacking p38alpha and p38delta can differentiate to endothelial cells, smooth muscle cells, and epithelial cells.
Q45090963Multiple activation mechanisms of p38alpha mitogen-activated protein kinase
Q37425407Mutations associated with retinopathies alter mitogen-activated protein kinase-induced phosphorylation of neural retina leucine-zipper
Q44893106NMDA and AMPA receptor expression and cortical neuronal death are associated with p38 in glutamate-induced excitotoxicity in vivo
Q36739616Natural variability in Drosophila larval and pupal NaCl tolerance
Q34462888Negative feedback regulation of MKK6 mRNA stability by p38alpha mitogen-activated protein kinase
Q33613972Nemo-like kinase, an essential effector of anterior formation, functions downstream of p38 mitogen-activated protein kinase.
Q42031613Nerve growth factor-induced cell cycle reentry in newborn neurons is triggered by p38MAPK-dependent E2F4 phosphorylation
Q43243455Neurodegenerative, with expression ATF-2 by p38 in cortical neurons.
Q28679143Neuronal p38 MAPK signalling: an emerging regulator of cell fate and function in the nervous system
Q44402659Nitric oxide-induced epidermal growth factor-dependent phosphorylations in A431 tumour cells.
Q37230433Nonsteroidal anti-inflammatory drug-activated gene-1 expression inhibits urethane-induced pulmonary tumorigenesis in transgenic mice
Q39563966Nonstructural 3 protein of hepatitis C virus triggers an oxidative burst in human monocytes via activation of NADPH oxidase.
Q35920795Nuclear factor of activated T cells c is a target of p38 mitogen-activated protein kinase in T cells
Q41487865OSU-DY7, a novel D-tyrosinol derivative, mediates cytotoxicity in chronic lymphocytic leukaemia and Burkitt lymphoma through p38 mitogen-activated protein kinase pathway
Q41123019Oscillatory dynamics of p38 activity with transcriptional and translational time delays
Q36952671Overexpression of mitogen-activated protein kinase kinase 6 in the heart improves functional recovery from ischemia in vitro and protects against myocardial infarction in vivo
Q38191702Oxidative stress response pathways: Fission yeast as archetype
Q40451806Oxidized low-density lipoprotein-induced apoptosis is attenuated by insulin-activated phosphatidylinositol 3-kinase/Akt through p38 mitogen-activated protein kinase.
Q40509976P38 alpha mitogen-activated protein kinase sensitizes cells to apoptosis induced by different stimuli.
Q36437685PP2AC Level Determines Differential Programming of p38-TSC-mTOR Signaling and Therapeutic Response to p38-Targeted Therapy in Colorectal Cancer
Q43263762Pharmacologically activated migration of aortic endothelial cells is mediated through p38 SAPK.
Q40760829Phosphatidylinositol 3-kinase controls human intestinal epithelial cell differentiation by promoting adherens junction assembly and p38 MAPK activation.
Q34016207Phosphorylation of EEA1 by p38 MAP kinase regulates mu opioid receptor endocytosis
Q35213239Phosphorylation of Raptor by p38beta participates in arsenite-induced mammalian target of rapamycin complex 1 (mTORC1) activation
Q31629257Phosphorylation-induced change of the oligomerization state of alpha B-crystallin
Q38784376Physalin A induces G2/M phase cell cycle arrest in human non-small cell lung cancer cells: involvement of the p38 MAPK/ROS pathway
Q40623656Physical stress by magnetic force accelerates differentiation of human osteoblasts
Q36146787Protective effect of 3-O-methyl quercetin and kaempferol from Semecarpus anacardium against H2O2 induced cytotoxicity in lung and liver cells.
Q39539256Protective effect of a Chrysanthemum indicum containing formulation in cadmium-induced ototoxicity
Q50938980Protein Tyrosine Signaling and its Potential Therapeutic Implications in Carcinogenesis.
Q24563065Protein kinase Cdelta regulates keratinocyte death and survival by regulating activity and subcellular localization of a p38delta-extracellular signal-regulated kinase 1/2 complex
Q35037746Protein kinases and their involvement in the cellular responses to genotoxic stress.
Q35635542Protein kinases in the regulation of apoptosis in B-cell chronic lymphocytic leukemia
Q21136385REX-1 expression and p38 MAPK activation status can determine proliferation/differentiation fates in human mesenchymal stem cells
Q38362019Rac1-MKK3-p38-MAPKAPK2 pathway promotes urokinase plasminogen activator mRNA stability in invasive breast cancer cells
Q28211306Ras participates in the activation of p38 MAPK by interleukin-1 by associating with IRAK, IRAK2, TRAF6, and TAK-1
Q24679707Regulation of PRAK subcellular location by p38 MAP kinases
Q40141729Regulation of apoptosis signal-regulating kinase 1 by protein phosphatase 2Cepsilon
Q38916274Regulation of centriolar satellite integrity and its physiology
Q39847460Regulation of endothelial protein C receptor shedding by cytokines is mediated through differential activation of MAP kinase signaling pathways
Q35923996Regulation of the activity of p38 mitogen-activated protein kinase by Akt in cancer and adenoviral protein E1A-mediated sensitization to apoptosis
Q39465762Regulation of the p38 mitogen-activated protein kinase and dual-specificity phosphatase 1 feedback loop modulates the induction of interleukin 6 and 8 in cells infected with coronavirus infectious bronchitis virus.
Q28505919Regulation of vertebrate myotome development by the p38 MAP kinase-MEF2 signaling pathway
Q35072903Rice MAPKs
Q40028122Role for mitogen-activated protein kinase p38 alpha in lung epithelial branching morphogenesis
Q44488190Role of the p38 MAPK pathway in cisplatin-based therapy
Q24299813SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7
Q37581437SOCS1 favors the epithelial-mesenchymal transition in melanoma, promotes tumor progression and prevents antitumor immunity by PD-L1 expression
Q39957413Sea urchin deciliation induces thermoresistance and activates the p38 mitogen-activated protein kinase pathway.
Q39674577Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence
Q37560607Signal integration by JNK and p38 MAPK pathways in cancer development
Q81563180Simulated microgravity activates MAPK pathways in fibroblasts cultured on microgrooved surface topography
Q52774264Skeletal muscle myogenesis is regulated by G protein-coupled receptor kinase 2.
Q52623512Subchronic microcystin-LR exposure increased hepatic apoptosis and induced compensatory mechanisms in mice.
Q41771840TEF-1 and C/EBPbeta are major p38alpha MAPK-regulated transcription factors in proliferating cardiomyocytes.
Q33905516TNF and MAP kinase signalling pathways
Q73692378TNF-alpha inhibits UCP-1 expression in brown adipocytes via ERKs. Opposite effect of p38MAPK
Q28361340TRAF6 is a critical mediator of signal transduction by the viral oncogene latent membrane protein 1
Q83230375Telomerase inhibition with a novel G-quadruplex-interactive agent, telomestatin: in vitro and in vivo studies in acute leukemia
Q28348605The Usf-1 transcription factor is a novel target for the stress-responsive p38 kinase and mediates UV-induced Tyrosinase expression.
Q36011824The brown adipose cell: a model for understanding the molecular mechanisms of insulin resistance.
Q36109992The cerebral cavernous malformation pathway controls cardiac development via regulation of endocardial MEKK3 signaling and KLF expression.
Q34004606The challenges of translating knockout phenotypes into gene function
Q45796015The dietary histone deacetylase inhibitor sulforaphane induces human beta-defensin-2 in intestinal epithelial cells
Q37292416The interactions of flavonoids within neuronal signalling pathways
Q38019033The many faces of p38 mitogen-activated protein kinase in progenitor/stem cell differentiation.
Q36592365The p38 MAPK stress pathway as a tumor suppressor or more?
Q43976249The p38 and JNK pathways cooperate to trans-activate vitamin D receptor via c-Jun/AP-1 and sensitize human breast cancer cells to vitamin D(3)-induced growth inhibition
Q52132212The p38 mitogen-activated protein kinase is involved in associative learning in rabbits.
Q27437628The p38/MK2/Hsp25 pathway is required for BMP-2-induced cell migration
Q28189507The proto-oncoprotein Brx activates estrogen receptor beta by a p38 mitogen-activated protein kinase pathway
Q33619118The role of nuclear factor I-C in tooth and bone development.
Q36974540The role of p38 in mitochondrial respiration in male and female mice
Q51265841The role of p38alpha in Schwann cells in regulating peripheral nerve myelination and repair.
Q33838890The role of p38alpha mitogen-activated protein kinase gene in the HELLP syndrome
Q39996855The role of repair protein Rad51 in synergistic cytotoxicity and mutagenicity induced by epidermal growth factor receptor inhibitor (Gefitinib, IressaR) and benzo[a]pyrene in human lung cancer.
Q100694481The role of stress kinases in metabolic disease
Q33328969The small molecule Mek1/2 inhibitor U0126 disrupts the chordamesoderm to notochord transition in zebrafish
Q39428879The status of phosphorylated p38 in esophageal squamous cell carcinoma
Q42239898The stress-activated protein kinases p38α/β and JNK1/2 cooperate with Chk1 to inhibit mitotic entry upon DNA replication arrest
Q45284019The suppressive role of p38 MAPK in cellular vacuole formation
Q34075110Therapeutic potential of anti-inflammatory drugs in focal stroke
Q39147015Thymoquinone induces apoptosis in oral cancer cells through p38β inhibition
Q48499441Time-dependent modulation of mitogen activated protein kinases and AKT in rat hippocampus and cortex in the pilocarpine model of epilepsy
Q44362242Transcriptional regulation of heme oxygenase-1 gene expression by MAP kinases of the JNK and p38 pathways in primary cultures of rat hepatocytes
Q24550794Transforming growth factor-beta1 (TGF-beta)-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of p38 by TGF-beta-activated kinase 1 and mitogen-activated protein kinase kinase 3
Q35153367Tumor necrosis factor-alpha stimulates the epithelial-to-mesenchymal transition of human colonic organoids
Q40768240Two clusters of residues at the docking groove of mitogen-activated protein kinases differentially mediate their functional interaction with the tyrosine phosphatases PTP-SL and STEP.
Q34281252Ubiquitin-conjugating enzyme Ubc13 controls breast cancer metastasis through a TAK1-p38 MAP kinase cascade
Q34433609Voltage-gated sodium channel Nav1.6 is modulated by p38 mitogen-activated protein kinase.
Q33534917Whole genome analysis of p38 SAPK-mediated gene expression upon stress.
Q37367898Xp38gamma/SAPK3 promotes meiotic G(2)/M transition in Xenopus oocytes and activates Cdc25C.
Q38350050Xp42Mpk1 Activation Is Not Required for Germinal Vescicle Breakdown but for Raf Complete Phosphorylation in Insulin-stimulated Xenopus Oocytes
Q34762154Yeast go the whole HOG for the hyperosmotic response
Q34415888p38 MAP kinase inhibition enables proliferation of adult mammalian cardiomyocytes
Q45959301p38 MAP kinase inhibits neutrophil development through phosphorylation of C/EBPalpha on serine 21.
Q44548770p38 MAP kinase mediates both short-term and long-term synaptic depression in aplysia.
Q79604064p38 MAP kinase regulation of oligodendrocyte differentiation with CREB as a potential target
Q43003484p38 MAP kinase signalling is required for hypertrophic chondrocyte differentiation
Q42126197p38 MAPK down-regulates fibulin 3 expression through methylation of gene regulatory sequences: role in migration and invasion.
Q40705683p38 MAPK mediates acid-induced transcription of PEPCK in LLC-PK(1)-FBPase(+) cells
Q36993715p38 Mitogen-activated protein kinase mediates a negative inotropic effect in cardiac myocytes
Q36997755p38 Mitogen-activated protein kinase regulates myelination
Q45061797p38 Mitogen-activated protein kinase regulation of endothelial cell migration depends on urokinase plasminogen activator expression
Q39380148p38 Mitogen-activated protein kinase signaling, ERCC1 expression, and viability of lung cancer cells from never or light smoker patients
Q36946945p38 alpha MAPK inhibits JNK activation and collaborates with IkappaB kinase 2 to prevent endotoxin-induced liver failure
Q48144894p38 differentially regulates ERK, p21, and mitogenic signalling in two pancreatic carcinoma cell lines
Q42807486p38 isoforms have opposite effects on AP-1-dependent transcription through regulation of c-Jun. The determinant roles of the isoforms in the p38 MAPK signal specificity
Q35746379p38 mitogen-activated protein kinase inhibitor SB203580 reverses the antianalgesia induced by dextro-morphine or morphine in the mouse spinal cord
Q50923980p38 mitogen-activated protein kinase is required for central nervous system myelination.
Q36399260p38-MAPK signals survival by phosphorylation of caspase-8 and caspase-3 in human neutrophils
Q81579931p38alpha MAP kinase-deficient mouse embryonic stem cells can differentiate to endothelial cells, smooth muscle cells, and neurons
Q50949746p38alpha MAPK can positively or negatively regulate Rac-1 activity depending on the presence of serum.
Q24657888p38alpha and p38gamma mediate oncogenic ras-induced senescence through differential mechanisms
Q34667875p38alpha antagonizes p38gamma activity through c-Jun-dependent ubiquitin-proteasome pathways in regulating Ras transformation and stress response
Q34684156p38α (MAPK14) critically regulates the immunological response and the production of specific cytokines and chemokines in astrocytes
Q61776576p38α MAP kinase is essential in lung stem and progenitor cell proliferation and differentiation
Q34008781p38α MAPK pathway: a key factor in colorectal cancer therapy and chemoresistance.
Q42773720p38α MAPK regulates adult muscle stem cell fate by restricting progenitor proliferation during postnatal growth and repair
Q91899588p38α Mitogen-Activated Protein Kinase Is a Druggable Target in Pancreatic Adenocarcinoma
Q39408183p38α limits the contribution of MAP17 to cancer progression in breast tumors
Q35710005p38α mediates cell survival in response to oxidative stress via induction of antioxidant genes: effect on the p70S6K pathway
Q39362199p38β MAP kinase as a therapeutic target for pancreatic cancer
Q37091827p38β, A novel regulatory target of Pokemon in hepatic cells
Q41157594p38γ regulates UV-induced checkpoint signaling and repair of UV-induced DNA damage
Q39089001β-Amyloid-evoked apoptotic cell death is mediated through MKK6-p66shc pathway

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