scholarly article | Q13442814 |
P356 | DOI | 10.1128/MCB.25.23.10454-10464.2005 |
P8608 | Fatcat ID | release_v2sawrzthfg2niocxyfzyvrb7i |
P932 | PMC publication ID | 1291241 |
P698 | PubMed publication ID | 16287858 |
P50 | author | Giorgos Kollias | Q11260534 |
Simon J. Arthur | Q46843760 | ||
Marietta Armaka | Q49464153 | ||
P2093 | author name string | Laura J Armit | |
Victoria A Beardmore | |||
Heather J Hinton | |||
Carol Clacher | |||
Julia M Carr | |||
Maria Apostolaki | |||
Christina Eftychi | |||
Joanne Darragh | |||
Joanne McIlrath | |||
Loraine Malone | |||
P2860 | cites work | Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways | Q24309037 |
Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB | Q24319704 | ||
A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3 | Q24320233 | ||
The protein kinase complement of the human genome | Q24324497 | ||
MSK1 and MSK2 are required for the mitogen- and stress-induced phosphorylation of CREB and ATF1 in fibroblasts | Q24537233 | ||
p38gamma regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP | Q24555714 | ||
Activation of the p38 mitogen-activated protein kinase pathway arrests cell cycle progression and differentiation of immature thymocytes in vivo | Q36375760 | ||
Feedback control of the protein kinase TAK1 by SAPK2a/p38 | Q40240134 | ||
Molecular determinants that mediate selective activation of p38 MAP kinase isoforms | Q40387373 | ||
MAPK p38 alpha is dispensable for lymphocyte development and proliferation. | Q40468334 | ||
MSK1 activity is controlled by multiple phosphorylation sites. | Q40487132 | ||
The in vivo role of PtdIns(3,4,5)P3 binding to PDK1 PH domain defined by knockin mutation | Q40561467 | ||
Role of CSB/p38/RK stress response kinase in LPS and cytokine signaling mechanisms | Q40971614 | ||
Differential involvement of p38 mitogen-activated protein kinase kinases MKK3 and MKK6 in T-cell apoptosis | Q42093335 | ||
Conversion of SB 203580-insensitive MAP kinase family members to drug-sensitive forms by a single amino-acid substitution | Q42541263 | ||
MSKs are required for the transcription of the nuclear orphan receptors Nur77, Nurr1 and Nor1 downstream of MAPK signalling. | Q42953889 | ||
Acquisition of sensitivity of stress-activated protein kinases to the p38 inhibitor, SB 203580, by alteration of one or more amino acids within the ATP binding pocket | Q47982160 | ||
Intrathymic signals in thymocytes are mediated by p38 mitogen-activated protein kinase. | Q52519672 | ||
Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for activation of p38alpha and p38delta MAPK isoforms by TGF-beta 1 in murine mesangial cells. | Q52547825 | ||
Impaired On/Off Regulation of TNF Biosynthesis in Mice Lacking TNF AU-Rich Elements | Q62819809 | ||
Essential role of p38alpha MAP kinase in placental but not embryonic cardiovascular development | Q74191149 | ||
Effect of SB 203580 on the activity of c-Raf in vitro and in vivo | Q77733964 | ||
Structural basis for p38alpha MAP kinase quinazolinone and pyridol-pyrimidine inhibitor specificity | Q27641774 | ||
MAPK-regulated transcription: a continuously variable gene switch? | Q28217211 | ||
Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction | Q28271470 | ||
Deficiency of the stress kinase p38alpha results in embryonic lethality: characterization of the kinase dependence of stress responses of enzyme-deficient embryonic stem cells | Q28343994 | ||
Requirement for p38alpha in erythropoietin expression: a role for stress kinases in erythropoiesis | Q28505039 | ||
Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for tumor necrosis factor-induced cytokine expression | Q28507834 | ||
Defective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3 (Mkk3)-deficient mice | Q28509000 | ||
Purification and identification of a major activator for p38 from osmotically shocked cells. Activation of mitogen-activated protein kinase kinase 6 by osmotic shock, tumor necrosis factor-alpha, and H2O2 | Q28509037 | ||
Isolation of TAO1, a protein kinase that activates MEKs in stress-activated protein kinase cascades | Q28566826 | ||
MK2 targets AU-rich elements and regulates biosynthesis of tumor necrosis factor and interleukin-6 independently at different post-transcriptional levels | Q28586348 | ||
MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis | Q28593865 | ||
Essential role for p38alpha mitogen-activated protein kinase in placental angiogenesis | Q28594675 | ||
Selective activation of p38 mitogen-activated protein (MAP) kinase isoforms by the MAP kinase kinases MKK3 and MKK6 | Q28678886 | ||
Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation | Q29614227 | ||
Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases | Q29614338 | ||
On the role of tumor necrosis factor and receptors in models of multiorgan failure, rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease | Q33333935 | ||
The p38 signal transduction pathway: activation and function | Q33838955 | ||
p38 MAP kinases: beyond the stress response | Q33934138 | ||
Inhibition of p38 MAP kinase as a therapeutic strategy | Q33957191 | ||
Interleukin-10 targets p38 MAPK to modulate ARE-dependent TNF mRNA translation and limit intestinal pathology. | Q34081023 | ||
MAP-kinase signaling pathways in T cells | Q34282347 | ||
Cellular mutants define a common mRNA degradation pathway targeting cytokine AU-rich elements | Q34364003 | ||
Activation and signaling of the p38 MAP kinase pathway | Q34390191 | ||
Identification and characterization of a predominant isoform of human MKK3. | Q34416895 | ||
MAP kinases in the immune response | Q34542231 | ||
An efficient proteomics method to identify the cellular targets of protein kinase inhibitors. | Q34787933 | ||
Mixed-lineage kinase control of JNK and p38 MAPK pathways | Q34810173 | ||
In the cellular garden of forking paths: how p38 MAPKs signal for downstream assistance | Q35009282 | ||
PI3K-signalling in B- and T-cells: insights from gene-targeted mice | Q35053089 | ||
Inhibitors of p38 mitogen-activated protein kinase for the treatment of rheumatoid arthritis. | Q35165967 | ||
p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases | Q35209995 | ||
The p38 MAP kinase pathway as a therapeutic target in inflammatory disease | Q35834912 | ||
Modeling the function of tumor necrosis factor in immune pathophysiology | Q35862356 | ||
Mechanism of p38 MAP kinase activation in vivo. | Q35967224 | ||
New therapies for rheumatoid arthritis | Q36088346 | ||
P433 | issue | 23 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 10454-10464 | |
P577 | publication date | 2005-12-01 | |
P1433 | published in | Molecular and Cellular Biology | Q3319478 |
P1476 | title | Generation and characterization of p38beta (MAPK11) gene-targeted mice | |
P478 | volume | 25 |
Q37649076 | "Go upstream, young man": lessons learned from the p38 saga |
Q28584161 | Activation of ASK1, downstream MAPKK and MAPK isoforms during cardiac ischaemia |
Q28387063 | Activation of p38 MAP kinase and JNK pathways by UVA irradiation |
Q54356167 | Alternative p38 MAPKs are essential for collagen-induced arthritis. |
Q37179387 | An essential role for p38 MAPK in cerebellar granule neuron precursor proliferation |
Q91622079 | Astrocytic p38α MAPK drives NMDA receptor-dependent long-term depression and modulates long-term memory |
Q39463481 | Characterization of the cellular action of the MSK inhibitor SB-747651A. |
Q37265027 | Cross talk between the Akt and p38α pathways in macrophages downstream of Toll-like receptor signaling |
Q33636430 | Crosstalk in inflammation: the interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatases |
Q38057357 | Cytoprotective signaling and gene expression in endothelial cells and macrophages-lessons for atherosclerosis |
Q34638032 | Dectin-1 regulates IL-10 production via a MSK1/2 and CREB dependent pathway and promotes the induction of regulatory macrophage markers |
Q34607153 | Deficiency in p38β MAPK fails to inhibit cytokine production or protect neurons against inflammatory insult in in vitro and in vivo mouse models |
Q47097391 | Differential Effects of Inhibitor Combinations on Lysophosphatidic Acid-Mediated Chemokine Secretion in Unprimed and Tumor Necrosis Factor-α-Primed Synovial Fibroblasts. |
Q33939763 | Endothelial and macrophage-specific deficiency of P38α MAPK does not affect the pathogenesis of atherosclerosis in ApoE-/- mice |
Q35969116 | Epigenetic modifiers reduce inflammation and modulate macrophage phenotype during endotoxemia-induced acute lung injury |
Q42438492 | Eukaryotic elongation factor 2 controls TNF-α translation in LPS-induced hepatitis |
Q37688086 | Functional roles of p38 mitogen-activated protein kinase in macrophage-mediated inflammatory responses |
Q24598036 | Gadd45γ and Map3k4 interactions regulate mouse testis determination via p38 MAPK-mediated control of Sry expression |
Q35672032 | Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38alpha in abrogating myoblast proliferation |
Q28589176 | Genetic analysis of specific and redundant roles for p38alpha and p38beta MAPKs during mouse development |
Q36197114 | High-resolution protein interaction map of the Drosophila melanogaster p38 mitogen-activated protein kinases reveals limited functional redundancy |
Q57059658 | Hsp70 interacts with MAPK-activated protein kinase 2 to regulate p38MAPK stability and myoblast differentiation during skeletal muscle regeneration |
Q34579680 | Hyperactive variants of p38alpha induce, whereas hyperactive variants of p38gamma suppress, activating protein 1-mediated transcription |
Q40206010 | Identification of novel phosphorylation sites in MSK1 by precursor ion scanning MS. |
Q36706331 | In vivo functions of mitogen-activated protein kinases: conclusions from knock-in and knock-out mice |
Q36238033 | Inhibition of JAKs in macrophages increases lipopolysaccharide-induced cytokine production by blocking IL-10-mediated feedback |
Q43116264 | Inhibition of neuronal p38α, but not p38β MAPK, provides neuroprotection against three different neurotoxic insults. |
Q34733108 | Inhibitory effects of intrathecal p38β antisense oligonucleotide on bone cancer pain in rats |
Q92255220 | Knocking down of LINC01220 inhibits proliferation and induces apoptosis of endometrial carcinoma through silencing MAPK11 |
Q36647424 | LY2228820 dimesylate, a selective inhibitor of p38 mitogen-activated protein kinase, reduces angiogenic endothelial cord formation in vitro and in vivo. |
Q35230204 | Lack of the T cell-specific alternative p38 activation pathway reduces autoimmunity and inflammation |
Q37623379 | Loss of Functionally Redundant p38 Isoforms in T Cells Enhances Regulatory T Cell Induction |
Q33991251 | Loss of cystic fibrosis transmembrane conductance regulator function enhances activation of p38 and ERK MAPKs, increasing interleukin-6 synthesis in airway epithelial cells exposed to Pseudomonas aeruginosa |
Q38567096 | MAP Kinase Cascades in Antigen Receptor Signaling and Physiology |
Q37508518 | MAPK signaling pathways in the regulation of hematopoiesis |
Q36745371 | MKK signaling and vascularization. |
Q54454015 | MSK1 regulates the transcription of IL-1ra in response to TLR activation in macrophages. |
Q42159260 | Mammary branch initiation and extension are inhibited by separate pathways downstream of TGFβ in culture |
Q27679954 | Mechanism and consequence of the autoactivation of p38α mitogen-activated protein kinase promoted by TAB1 |
Q38088305 | Mechanisms of the joint-protective effects of p38 MAPK inhibitors in rodent arthritis |
Q34776420 | Mice with a conditional deletion of the neurotrophin receptor TrkB are dwarfed, and are similar to mice with a MAPK14 deletion |
Q37504948 | Mitochondrial p38β and manganese superoxide dismutase interaction mediated by estrogen in cardiomyocytes |
Q37802466 | Mitogen-activated protein kinases in hepatocellular carcinoma development |
Q27865268 | Mitogen-activated protein kinases in innate immunity |
Q27644283 | Molecular basis of MAPK-activated protein kinase 2:p38 assembly |
Q41767222 | Mouse embryonic stem cells lacking p38alpha and p38delta can differentiate to endothelial cells, smooth muscle cells, and epithelial cells. |
Q33613972 | Nemo-like kinase, an essential effector of anterior formation, functions downstream of p38 mitogen-activated protein kinase. |
Q37349777 | Noninvasive detection of candidate molecular biomarkers in subjects with a history of insulin resistance and colorectal adenomas |
Q42380665 | Novel Noncatalytic Substrate-Selective p38α-Specific MAPK Inhibitors with Endothelial-Stabilizing and Anti-Inflammatory Activity. |
Q28646177 | Nuclear localization of p38 MAPK in response to DNA damage |
Q92859614 | Phenotype-Based Screens with Conformation-Specific Inhibitors Reveal p38 Gamma and Delta as Targets for HCC Polypharmacology |
Q52608079 | Phosphorylation of cAMP-specific PDE4A5 (phosphodiesterase-4A5) by MK2 (MAPKAPK2) attenuates its activation through protein kinase A phosphorylation. |
Q46261780 | Reduced oxazolone-induced skin inflammation in MAPKAP kinase 2 knockout mice. |
Q26742080 | Redundancy in the World of MAP Kinases: All for One |
Q24314902 | Regulation of PKD by the MAPK p38delta in insulin secretion and glucose homeostasis |
Q35728290 | Regulation of sodium iodide symporter gene expression by Rac1/p38β mitogen-activated protein kinase signaling pathway in MCF-7 breast cancer cells |
Q91972740 | Role of Alterations in Protein Kinase p38γ in the Pathogenesis of the Synaptic Pathology in Dementia With Lewy Bodies and α-Synuclein Transgenic Models |
Q57065048 | Role of Mitogen Activated Protein Kinase Signaling in Parkinson's Disease |
Q46321255 | Role of Reactive Oxygen Species during Low-Intensity Pulsed Ultrasound Application in MC-3 T3 E1 Pre-osteoblast Cell Culture |
Q37392558 | Role of p38 MAP Kinase Signal Transduction in Solid Tumors |
Q40771606 | Role of spinal p38alpha and beta MAPK in inflammatory hyperalgesia and spinal COX-2 expression |
Q38366515 | Roles of p38α mitogen-activated protein kinase in mouse models of inflammatory diseases and cancer. |
Q36469025 | SB203580 increases G-CSF production via a stem-loop destabilizing element in the 3' untranslated region in macrophages independently of its effect on p38 MAPK activity |
Q36076268 | SB203580, a p38 inhibitor, improved cardiac function but worsened lung injury and survival during Escherichia coli pneumonia in mice. |
Q37504904 | Selective suppression of the α isoform of p38 MAPK rescues late-stage tau pathology. |
Q37560607 | Signal integration by JNK and p38 MAPK pathways in cancer development |
Q35685580 | Signaling via the kinase p38α programs dendritic cells to drive TH17 differentiation and autoimmune inflammation |
Q36910213 | Store-operated Ca2+ entry (SOCE) induced by protease-activated receptor-1 mediates STIM1 protein phosphorylation to inhibit SOCE in endothelial cells through AMP-activated protein kinase and p38β mitogen-activated protein kinase |
Q26781375 | Stress kinases in the modulation of metabolism and energy balance |
Q54121159 | Stress-Activated Protein Kinases in Spinal Cord Injury: Focus on Roles of p38. |
Q45305579 | Suppression of MAPK11 or HIPK3 reduces mutant Huntingtin levels in Huntington's disease models |
Q36371410 | Systematic identification of arsenic-binding proteins reveals that hexokinase-2 is inhibited by arsenic. |
Q42175314 | TGF-β1 induces endothelial cell apoptosis by shifting VEGF activation of p38(MAPK) from the prosurvival p38β to proapoptotic p38α. |
Q33905516 | TNF and MAP kinase signalling pathways |
Q34132268 | Targeted disruption of Mapk14 (p38MAPKalpha) in granulosa cells and cumulus cells causes cell-specific changes in gene expression profiles that rescue COC expansion and maintain fertility |
Q34624894 | Targeting dual-specificity phosphatases: manipulating MAP kinase signalling and immune responses. |
Q38026044 | The Role of p38 MAPK and Its Substrates in Neuronal Plasticity and Neurodegenerative Disease |
Q39140421 | The TGFβ-induced phosphorylation and activation of p38 mitogen-activated protein kinase is mediated by MAP3K4 and MAP3K10 but not TAK1. |
Q40789928 | The activation of p38 alpha, and not p38 beta, mitogen-activated protein kinase is required for ischemic preconditioning |
Q27320544 | The catalytic subunit of the system L1 amino acid transporter (slc7a5) facilitates nutrient signalling in mouse skeletal muscle |
Q36983159 | The kinase p38 alpha serves cell type-specific inflammatory functions in skin injury and coordinates pro- and anti-inflammatory gene expression |
Q46438489 | The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling |
Q38019033 | The many faces of p38 mitogen-activated protein kinase in progenitor/stem cell differentiation. |
Q36518938 | The many paths to p38 mitogen-activated protein kinase activation in the immune system |
Q41911172 | The mitogen-activated protein kinase (MAPK)-activated protein kinases MK2 and MK3 cooperate in stimulation of tumor necrosis factor biosynthesis and stabilization of p38 MAPK. |
Q34601353 | The mitogen-activated protein kinase p38α regulates tubular damage in murine anti-glomerular basement membrane nephritis |
Q36040645 | The p38 MAP Kinase Family as Regulators of Proinflammatory Cytokine Production in Degenerative Diseases of the CNS. |
Q38048776 | The p38 MAPK Pathway in Rheumatoid Arthritis: A Sideways Look |
Q37620350 | The p38 MAPK inhibitors for the treatment of inflammatory diseases and cancer |
Q24617740 | The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice |
Q36592365 | The p38 MAPK stress pathway as a tumor suppressor or more? |
Q36934993 | The p38 mitogen-activated protein kinase (MAPK) pathway in rheumatoid arthritis |
Q34148893 | The p38 mitogen-activated protein kinase pathway--a potential target for intervention in infarction, hypertrophy, and heart failure |
Q27437628 | The p38/MK2/Hsp25 pathway is required for BMP-2-induced cell migration |
Q33875419 | The p38α MAPK function in osteoprecursors is required for bone formation and bone homeostasis in adult mice |
Q44870828 | The role of p38 mitogen-activated kinase (MAPK) in the mechanism regulating cyclooxygenase gene expression in equine leukocytes. |
Q100694481 | The role of stress kinases in metabolic disease |
Q36128415 | The sodium iodide symporter (NIS): regulation and approaches to targeting for cancer therapeutics |
Q36461109 | Transcription factor and kinase-mediated signaling in atherosclerosis and vascular injury |
Q24336073 | Vascular endothelial growth factor induces heat shock protein (HSP) 27 serine 82 phosphorylation and endothelial tubulogenesis via protein kinase D and independent of p38 kinase |
Q34712108 | miR-132/212 knockout mice reveal roles for these miRNAs in regulating cortical synaptic transmission and plasticity |
Q45959301 | p38 MAP kinase inhibits neutrophil development through phosphorylation of C/EBPalpha on serine 21. |
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Q26747239 | p38 MAPK Signaling in Osteoblast Differentiation |
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Q36559764 | p38 and OGT sequestration into viral inclusion bodies in cells infected with human respiratory syncytial virus suppresses MK2 activities and stress granule assembly |
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Q24657888 | p38alpha and p38gamma mediate oncogenic ras-induced senescence through differential mechanisms |
Q53223893 | p38α and p38β mitogen-activated protein kinases determine cholinergic transdifferentiation of sympathetic neurons. |
Q28710107 | p38α mitogen-activated protein kinase depletion and repression of signal transduction to translation machinery by miR-124 and -128 in neurons |
Q50946132 | p38α regulates cytokine-induced IFNγ secretion via the Mnk1/eIF4E pathway in Th1 cells. |
Q92932117 | p38β MAPK mediates ULK1-dependent induction of autophagy in skeletal muscle of tumor-bearing mice |
Q49638733 | p38γ and p38δ Are Involved in T Lymphocyte Development. |
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Q36094132 | p38γ and p38δ kinases regulate the Toll-like receptor 4 (TLR4)-induced cytokine production by controlling ERK1/2 protein kinase pathway activation |
Q36635737 | p38γ and p38δ reprogram liver metabolism by modulating neutrophil infiltration. |
Q41093817 | p38γ and δ promote heart hypertrophy by targeting the mTOR-inhibitory protein DEPTOR for degradation. |
Q41157594 | p38γ regulates UV-induced checkpoint signaling and repair of UV-induced DNA damage |
Q38260028 | p38δ MAPK: Emerging Roles of a Neglected Isoform |
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