Aberrant DNA methylation is associated with disease progression, resistance to imatinib and shortened survival in chronic myelogenous leukemia

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Aberrant DNA methylation is associated with disease progression, resistance to imatinib and shortened survival in chronic myelogenous leukemia is …
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scholarly articleQ13442814

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P819ADS bibcode2011PLoSO...622110J
P356DOI10.1371/JOURNAL.PONE.0022110
P932PMC publication ID3132778
P698PubMed publication ID21760961
P5875ResearchGate publication ID51494308

P50authorMarcos EstecioQ41192024
Jean-Pierre J IssaQ55459879
Jorge Eduardo CortesQ60320900
Hagop KantarjianQ60394812
Nianxiang ZhangQ86407993
Woonbok ChungQ92086738
Vazganush GharibyanQ114428015
Kimie KondoQ117223256
P2093author name stringShoudan Liang
Yue Lu
Jaroslav Jelinek
Rong He
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Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosomeQ28287810
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LINE-1 hypomethylation in cancer is highly variable and inversely correlated with microsatellite instabilityQ33283510
DNA methylation predicts survival and response to therapy in patients with myelodysplastic syndromesQ33628772
Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl proteinQ33682660
Progressive de novo DNA methylation at the bcr-abl locus in the course of chronic myelogenous leukemiaQ35871366
High-throughput methylation profiling by MCA coupled to CpG island microarrayQ36004673
Epigenetic changes in solid and hematopoietic tumors.Q36279348
Correlation between CpG methylation profiles and hormone receptor status in breast cancersQ36393321
Identification of novel tumor markers in prostate, colon and breast cancer by unbiased methylation profilingQ36571511
Aberrant CpG island methylation in acute myeloid leukemia is accentuated at relapseQ36835063
Aberrant DNA methylation is a dominant mechanism in MDS progression to AML.Q37086937
Reversion-induced LIM interaction with Src reveals a novel Src inactivation cycleQ37234340
Genome-wide screen of promoter methylation identifies novel markers in melanoma.Q37287368
Treatment selection after imatinib resistance in chronic myeloid leukemiaQ37431597
Imatinib and beyond--exploring the full potential of targeted therapy for CML.Q37571446
A genome-wide screen identifies frequently methylated genes in haematological and epithelial cancersQ39628888
CpG island methylation profiling in human melanoma cell lines.Q39851708
PDLIM4, an actin binding protein, suppresses prostate cancer cell growthQ39884402
Methylation status of RASSF1A in patients with chronic myeloid leukemiaQ39887507
Genome-wide identification of aberrantly methylated promoter associated CpG islands in acute lymphocytic leukemia.Q39975102
Inactivation of HOXA genes by hypermethylation in myeloid and lymphoid malignancy is frequent and associated with poor prognosis.Q40085449
Phase II study of low-dose decitabine in combination with imatinib mesylate in patients with accelerated or myeloid blastic phase of chronic myelogenous leukemia.Q40459776
Phase II study of low-dose decitabine in patients with chronic myelogenous leukemia resistant to imatinib mesylateQ40508930
A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elementsQ40587967
DNA methylation in serum and tumors of cervical cancer patientsQ40593488
Identification of differentially methylated sequences in colorectal cancer by methylated CpG island amplificationQ40951949
The estrogen receptor CpG island is methylated in most hematopoietic neoplasms.Q41223399
Hypermethylation-associated inactivation indicates a tumor suppressor role for p15INK4B.Q41228119
Alterations in DNA methylation: a fundamental aspect of neoplasiaQ41617101
Quantitative measure of c-abl and p15 methylation in chronic myelogenous leukemia: biological implicationsQ41731985
Differential genome-wide array-based methylation profiles in prognostic subsets of chronic lymphocytic leukemiaQ43246242
Role of the nucleoplasmin 2 C-terminal domain in the formation of nucleolus-like bodies in mouse oocytesQ43266806
Promoter hypomethylation of the LINE-1 retrotransposable elements activates sense/antisense transcription and marks the progression of chronic myeloid leukemiaQ44500993
Epigenetic profiling in chronic lymphocytic leukemia reveals novel methylation targetsQ44826936
sFRP1 promoter methylation is associated with persistent Philadelphia chromosome in chronic myeloid leukemiaQ46177631
CpG island methylation and expression of the secreted frizzled-related protein gene family in chronic lymphocytic leukemiaQ46902022
Cloning, expression, and mutation analysis of NOR1, a novel human gene down-regulated in HNE1 nasopharyngeal carcinoma cell lineQ48239551
Alterations of DNA methylation and histone modifications contribute to gene silencing in hepatocellular carcinomas.Q51579451
RIL, a LIM gene on 5q31, is silenced by methylation in cancer and sensitizes cancer cells to apoptosis.Q55043439
Alterations in DNA Methylation: A Fundamental Aspect of NeoplasiaQ56418625
HIC1 hypermethylation is a late event in hematopoietic neoplasmsQ58290208
Distinct patterns of inactivation of p15INK4B and p16INK4A characterize the major types of hematological malignanciesQ63641308
Abnormal methylation of the calcitonin gene marks progression of chronic myelogenous leukemiaQ70167698
Repetitive DNA hypomethylation in the advanced phase of chronic myeloid leukemiaQ80979924
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectleukemiaQ29496
imatinibQ177094
DNA methylationQ874745
P304page(s)e22110
P577publication date2011-07-08
P1433published inPLOS OneQ564954
P1476titleAberrant DNA methylation is associated with disease progression, resistance to imatinib and shortened survival in chronic myelogenous leukemia
P478volume6

Reverse relations

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