Poor prognostic clinicopathologic features correlate with VEGF expression but not with PTEN expression in squamous cell carcinoma of the larynx

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Poor prognostic clinicopathologic features correlate with VEGF expression but not with PTEN expression in squamous cell carcinoma of the larynx is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1042133867
P356DOI10.1186/1746-1596-5-35
P932PMC publication ID2904738
P698PubMed publication ID20546613
P5875ResearchGate publication ID44671827

P50authorBedri KandemirQ116884254
P2093author name stringYurdanur Sullu
Sinan Atmaca
Filiz Karagoz
Seda Gun
P2860cites workPTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancerQ27860985
PTEN regulatory functions in tumor suppression and cell biologyQ28284719
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Clinical application of antiangiogenic therapy: microvessel density, what it does and doesn't tell us.Q34693504
Multiple regulatory pathways of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) expression in tumorsQ35690266
Inactivation of PTEN is associated with increased angiogenesis and VEGF overexpression in gastric cancerQ36178164
PI3K/PTEN signaling in tumorigenesis and angiogenesisQ36982971
Overview of current and future biologically based targeted therapies in head and neck squamous cell carcinomaQ37414399
VEGF is up-regulated by hypoxic stimulation and related to tumour angiogenesis and severity of disease in oral squamous cell carcinoma: in vitro and in vivo studiesQ40334624
Immunohistochemical evidence of PTEN in oral squamous cell carcinoma and its correlation with the histological malignancy grading systemQ40634516
Expression and significance of PTEN, hypoxia-inducible factor-1 alpha in colorectal adenoma and adenocarcinomaQ41973966
PTEN and LKB1 genes in laryngeal tumoursQ43076526
Tumor angiogenesis: a new significant and independent prognostic indicator in early-stage breast carcinomaQ45952675
PIK3CA is implicated as an oncogene in ovarian cancer.Q46015944
Microvessel density and expression of vascular endothelial growth factor, basic fibroblast growth factor, and platelet-derived endothelial growth factor in oral squamous cell carcinomasQ46626227
VEGF and bFGF expression and microvessel density of maxillary sinus squamous cell carcinoma in relation to p53 status, spontaneous apoptosis and prognosisQ47606746
Basic fibroblast growth factor (bFGF) and vascular endothelial growth factor (VEGF) levels, as prognostic indicators in NSCLC.Q47955121
Frequent monoallelic deletion of PTEN and its reciprocal associatioin with PIK3CA amplification in gastric carcinoma.Q52549220
Somatic deletions and mutations in the Cowden disease gene, PTEN, in sporadic thyroid tumors.Q53439669
PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas.Q53629192
Microvessel density in head and neck squamous cell carcinoma primary tumors and its correlation with clinical staging parameters.Q53632247
Tumor angiogenesis as a prognostic factor in early oral tongue cancerQ71247492
Vascular endothelial growth factorQ73129419
Mutation analysis of the putative tumor suppressor gene PTEN/MMAC1 in advanced gastric carcinomasQ73271272
Expression of vascular endothelial growth factor receptors on tumor cells in head and neck squamous cell carcinomaQ73821812
The association between tumour progression and vascularity in the oral mucosaQ73882543
Expression of vascular endothelial growth factor and microvessel density in head and neck tumorigenesisQ74067255
Endoglin (CD105) expression in squamous cell carcinoma of the oral cavityQ77759709
Inactivation of the PTEN gene protein product is associated with the invasiveness and metastasis, but not angiogenesis, of breast cancerQ79366153
Expression of PTEN protein in patients with laryngeal squamous cell carcinomaQ80256287
Expression of c-erbB receptors, MMPs and VEGF in squamous cell carcinoma of the head and neckQ80342360
Prognostic significance of VEGF immunohistochemical expression and tumor angiogenesis in head and neck squamous cell carcinomaQ80934411
Mutation of the PIK3CA gene in ovarian and breast cancerQ80945762
Strong immunohistochemical expression of vascular endothelial growth factor predicts overall survival in head and neck squamous cell carcinomaQ81422492
P275copyright licenseCreative Commons Attribution 2.0 GenericQ19125117
P6216copyright statuscopyrightedQ50423863
P921main subjectlarynxQ9637
P304page(s)35
P577publication date2010-06-14
P1433published inDiagnostic PathologyQ18397261
P1476titlePoor prognostic clinicopathologic features correlate with VEGF expression but not with PTEN expression in squamous cell carcinoma of the larynx
P478volume5

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cites work (P2860)
Q53315227Brush cytology with immunocytochemical evaluation of VEGF expression versus biopsy in clinically precancerous laryngeal lesions: can we diagnose laryngeal cancer only with brush cytology?
Q55282044CD31 and VEGF are prognostic biomarkers in early-stage, but not in late-stage, laryngeal squamous cell carcinoma.
Q30584751CD44v/CD44s expression patterns are associated with the survival of pancreatic carcinoma patients
Q35974482Epigenetic dysregulation in laryngeal squamous cell carcinoma
Q37560826Expression of angiogenic growth factors in laryngeal carcinoma
Q36294075Larynx carcinoma regulates tumor-associated macrophages through PLGF signaling
Q37564494Low copy number of mitochondrial DNA (mtDNA) predicts worse prognosis in early-stage laryngeal cancer patients
Q47168379Overexpression of Antiangiogenic Vascular Endothelial Growth Factor Isoform and Splicing Regulatory Factors in Oral, Laryngeal and Pharyngeal Squamous Cell Carcinomas
Q90734120Prognostic implication of CEACAM1 expression in squamous cell carcinoma of the larynx: Pilot study
Q38018809The metastatic niche and stromal progression
Q37277702The relationship between lymphatic vascular density and vascular endothelial growth factor A (VEGF-A) expression with clinical-pathological features and survival in pancreatic adenocarcinomas
Q87374939Upregulation of serum vascular endothelial growth factor and matrix metalloproteinase-3 in patients with oral squamous cell carcinoma
Q37142987miR-203 is involved in the laryngeal carcinoma pathogenesis via targeting VEGFA and Cox-2.

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