| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/S0047-6374(00)00112-3 |
| P698 | PubMed publication ID | 10996019 |
| P2093 | author name string | Müller WE | |
| Schröder HC | |||
| Ushijima H | |||
| Laplanche JL | |||
| P2860 | cites work | Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine | Q24322674 |
| Activation of Raf-1 by 14-3-3 proteins | Q24324360 | ||
| Inducible expression of neuronal glutamate receptor channels in the NT2 human cell line | Q24563296 | ||
| Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins | Q24564014 | ||
| Prions | Q24633319 | ||
| Structure of amyloid A4-(1-40)-peptide of Alzheimer's disease | Q27729739 | ||
| Fatal familial insomnia, a prion disease with a mutation at codon 178 of the prion protein gene | Q28181555 | ||
| Apoptosis in the pathogenesis and treatment of disease | Q28235731 | ||
| 14-3-3 proteins interact with specific MEK kinases | Q28260788 | ||
| Glutathione | Q28261279 | ||
| Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L) | Q28297419 | ||
| gp120 of HIV-1 induces apoptosis in rat cortical cell cultures: prevention by memantine | Q28317192 | ||
| Copper stimulates endocytosis of the prion protein | Q28589040 | ||
| Inactivation of bcl-2 results in progressive degeneration of motoneurons, sympathetic and sensory neurons during early postnatal development | Q28590612 | ||
| Bcl-2 overexpression prevents motoneuron cell body loss but not axonal degeneration in a mouse model of a neurodegenerative disease | Q28591123 | ||
| The structural basis for 14-3-3:phosphopeptide binding specificity | Q29547190 | ||
| Cell death: the significance of apoptosis | Q29617620 | ||
| Synergistic effects of HIV coat protein and NMDA receptor-mediated neurotoxicity. | Q46152124 | ||
| Channel formation by a neurotoxic prion protein fragment | Q46437362 | ||
| Cytotoxicity of prion protein peptide (PrP106-126) differs in mechanism from the cytotoxic activity of the Alzheimer's disease amyloid peptide, A beta 25-35. | Q47634090 | ||
| Molecular pathology of fatal familial insomnia | Q47820843 | ||
| Prion protein is necessary for normal synaptic function | Q48087355 | ||
| Prion protein peptide neurotoxicity can be mediated by astrocytes | Q48127864 | ||
| Suppression of PrP(Sc)- and HIV-1 gp120 induced neuronal cell death by sulfated colominic acid. | Q48157650 | ||
| Brain penetration and in vivo recovery of NMDA receptor antagonists amantadine and memantine: a quantitative microdialysis study | Q48197949 | ||
| High neuron-specific enolase level of cerebrospinal fluid in the early stage of Creutzfeldt-Jakob disease | Q48219909 | ||
| MS-8209, a water-soluble amphotericin B derivative, affects both scrapie agent replication and PrPres accumulation in Syrian hamster scrapie | Q48231432 | ||
| Cytoprotective effect of NMDA receptor antagonists on prion protein (PrionSc)-induced toxicity in rat cortical cell cultures | Q48233046 | ||
| Astrocytic glutamate uptake and prion protein expression | Q48290049 | ||
| Activation of microglial cells by PrP and beta-amyloid fragments raises intracellular calcium through L-type voltage sensitive calcium channels | Q48301690 | ||
| Neurotoxicity of a prion protein fragment | Q48304223 | ||
| Phenotypic variability of Gerstmann-Sträussler-Scheinker disease is associated with prion protein heterogeneity. | Q48367656 | ||
| Immunohistochemical study of microglia in the Creutzfeldt-Jakob diseased brain | Q48379501 | ||
| High levels of nervous system-specific proteins in cerebrospinal fluid in patients with early stage Creutzfeldt-Jakob disease | Q48419470 | ||
| Detection of 14-3-3 protein in the cerebrospinal fluid supports the diagnosis of Creutzfeldt-Jakob disease | Q48550821 | ||
| Nearly ubiquitous tissue distribution of the scrapie agent precursor protein | Q48595206 | ||
| Secondary structure analysis of the scrapie-associated protein PrP 27-30 in water by infrared spectroscopy | Q48674139 | ||
| Protection of flupirtine on beta-amyloid-induced apoptosis in neuronal cells in vitro: prevention of amyloid-induced glutathione depletion. | Q48701951 | ||
| Effectiveness of anthracycline against experimental prion disease in Syrian hamsters | Q48706421 | ||
| Flupirtine reduces functional deficits and neuronal damage after global ischemia in rats | Q48726344 | ||
| Effects of the 1-amino-adamantanes at the MK-801-binding site of the NMDA-receptor-gated ion channel: a human postmortem brain study | Q48738084 | ||
| Abnormalities in stress proteins in prion diseases | Q48775242 | ||
| Intracellular calcium rise through L-type calcium channels, as molecular mechanism for prion protein fragment 106-126-induced astroglial proliferation. | Q48861725 | ||
| Pre-mortem diagnosis of Creutzfeldt-Jakob disease by detection of abnormal cerebrospinal fluid proteins | Q48886619 | ||
| The 14-3-3 brain protein in cerebrospinal fluid as a marker for transmissible spongiform encephalopathies | Q48913771 | ||
| Diagnostic criteria for sporadic Creutzfeldt-Jakob disease | Q48934056 | ||
| Role of microglia and host prion protein in neurotoxicity of a prion protein fragment | Q49050987 | ||
| Exacerbation of copper toxicity in primary neuronal cultures depleted of cellular glutathione. | Q51985324 | ||
| Programmed cell death and Bcl-2 protection in very low oxygen. | Q52208882 | ||
| Chemoprophylaxis of scrapie in mice | Q53030476 | ||
| Isoform pattern of 14-3-3 proteins in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease. | Q53231720 | ||
| Potent inhibition of scrapie-associated PrP accumulation by congo red | Q54131452 | ||
| S-100 protein concentration in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease | Q57274052 | ||
| Diagnosis of Creutzfeldt-Jakob disease by two-dimensional gel electrophoresis of cerebrospinal fluid | Q57274061 | ||
| Cerebrospinal fluid and serum concentrations of the N-methyl-D-aspartate (NMDA) receptor antagonist memantine in man. | Q57781109 | ||
| Cerebrospinal-fluid test for new-variant Creutzfeldt-Jakob disease | Q59691968 | ||
| Abnormal proteins in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease. | Q64960210 | ||
| Further analysis of nucleic acids in purified scrapie prion preparations by improved return refocusing gel electrophoresis | Q67518889 | ||
| Memantine is a potent blocker of N-methyl-D-aspartate (NMDA) receptor channels | Q69358445 | ||
| Detection of apoptosis in murine scrapie | Q70875757 | ||
| Regulation of intracellular free calcium levels by the cellular prion protein | Q71365172 | ||
| Flupirtine protects neurons against excitotoxic or ischemic damage and inhibits the increase in cytosolic Ca2+ concentration | Q71377073 | ||
| Neurotoxicity in rat cortical cells caused by N-methyl-D-aspartate (NMDA) and gp120 of HIV-1: induction and pharmacological intervention | Q71570724 | ||
| Maternal 3-methylglutaconic aciduria associated with abnormalities in offspring | Q71579726 | ||
| Implication of cyclosporine in up-regulation of Bcl-2 expression and maintenance of CD8 lymphocytosis in cytomegalovirus-infected allograft recipients | Q71700452 | ||
| Exposure to gp120 of HIV‐1 Induces an Increased Release of Arachidonic Acid in Rat Primary Neuronal Cell Culture Followed by NMDA Receptor‐mediated Neurotoxicity | Q71795847 | ||
| N-Methyl-d-aspartate and α2-adrenergic mechanisms are involved in the depressent action of flupirtine on spinal reflexes in rats | Q71845892 | ||
| The cellular prion protein (PrP) selectively binds to Bcl-2 in the yeast two-hybrid system | Q71873789 | ||
| Flupirtine protects against ischaemic retinal dysfunction in rats | Q72110358 | ||
| Immunohistochemical evidence for flupirtine acting as an antagonist on theN-methyl-d-aspartate and homocysteic acid-induced release of GABA in the rabbit retina | Q72111867 | ||
| The triaminopyridine flupirtine prevents cell death in rat cortical cells induced by N-methyl-D-aspartate and gp120 of HIV-1 | Q72130473 | ||
| Cerebrospinal fluid concentration of neuron-specific enolase in diagnosis of Creutzfeldt-Jakob disease | Q72318725 | ||
| Mouse cortical cells lacking cellular PrP survive in culture with a neurotoxic PrP fragment | Q72568587 | ||
| Creutzfeldt-Jakob disease: assessment and management | Q72620390 | ||
| PrP and β‐Amyloid Fragments Activate Different Neurotoxic Mechanisms in Cultured Mouse Cells | Q73494469 | ||
| Detection of 14-3-3 protein in the CSF of genetic Creutzfeldt-Jakob disease | Q73624596 | ||
| Effect of flupirtine on Bcl-2 and glutathione level in neuronal cells treated in vitro with the prion protein fragment (PrP106-126) | Q73820551 | ||
| 14-3-3 protein, neuron-specific enolase, and S-100 protein in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease | Q74587325 | ||
| Increase of neuron-specific enolase in patients with Creutzfeldt-Jakob disease | Q74614409 | ||
| Effect of flupirtine on cell death of human umbilical vein endothelial cells induced by reactive oxygen species | Q78109088 | ||
| Flupirtine protects both neuronal cells and lymphocytes against induced apoptosis in vitro: implications for treatment of AIDS patients | Q82498391 | ||
| Bcl-2 functions in an antioxidant pathway to prevent apoptosis | Q29620401 | ||
| Memantine is a clinically well tolerated N-methyl-D-aspartate (NMDA) receptor antagonist--a review of preclinical data | Q30580986 | ||
| Diagnosis of Creutzfeldt-Jakob disease and related human spongiform encephalopathies | Q32132961 | ||
| Oxidant, mitochondria and calcium: an overview | Q33537010 | ||
| Block of N-methyl-D-aspartate-activated current by the anticonvulsant MK-801: selective binding to open channels | Q33554934 | ||
| Role of the 37 kDa laminin receptor precursor in the life cycle of prions | Q33585086 | ||
| Bcl-2 family proteins as ion-channels | Q33592271 | ||
| Clinical aspects of human spongiform encephalopathies, with the exception of iatrogenic forms | Q33604080 | ||
| Memantine displaces [3H]MK-801 at therapeutic concentrations in postmortem human frontal cortex | Q34510586 | ||
| Flupirtine partially prevents neuronal injury induced by prion protein fragment and lead acetate | Q34735303 | ||
| Pharmacological intervention in age-associated brain disorders by Flupirtine: Alzheimer's and prion diseases | Q34747314 | ||
| MS-8209, a new amphotericin B derivative, provides enhanced efficacy in delaying hamster scrapie | Q35121108 | ||
| 14-3-3 proteins: a highly conserved, widespread family of eukaryotic proteins | Q35624026 | ||
| Scrapie prion proteins accumulate in the cytoplasm of persistently infected cultured cells | Q36223171 | ||
| Neurotoxicity of HIV coat protein gp120, NMDA receptors, and protein kinase C: A study with rat cerebellar granule cell cultures | Q36695384 | ||
| Creutzfeldt-Jakob disease in the elderly | Q36728053 | ||
| Predicted alpha-helical regions of the prion protein when synthesized as peptides form amyloid | Q37302673 | ||
| Sulfated glycans stimulate endocytosis of the cellular isoform of the prion protein, PrPC, in cultured cells. | Q38287981 | ||
| Flupirtine. A review of its pharmacological properties, and therapeutic efficacy in pain states | Q39494904 | ||
| Apoptosis in the Nervous System: Morphological Features, Methods, Pathology, and Prevention | Q40423446 | ||
| The role of intracellular oxidants in apoptosis | Q40437336 | ||
| Reactive oxygen species and the regulation of cell death by the Bcl-2 gene family | Q40437342 | ||
| Apoptotic death in an in vitro model of neuronal oxidative stress | Q40480393 | ||
| Fatal familial insomnia and familial Creutzfeldt-Jakob disease: clinical, pathological and molecular features. | Q40537014 | ||
| Biology and genetics of prion diseases | Q40573008 | ||
| 14-3-3 proteins: biological function and domain structure | Q40949003 | ||
| Neuronal cell death in scrapie-infected mice is due to apoptosis | Q40979839 | ||
| Protein folding, nucleation phenomena and delayed neurodegeneration in Alzheimer's disease. | Q41060585 | ||
| The anti-prion activity of Congo red. Putative mechanism | Q41062006 | ||
| Flupirtine increases the levels of glutathione and Bc1-2 in hNT (human Ntera/D1) neurons: mode of action of the drug-mediated anti-apoptotic effect | Q41145481 | ||
| Expression of bcl-2 inhibits cellular radical generation | Q41221774 | ||
| 1-methyl-4-phenyl-pyridinium ion (MPP+) causes DNA fragmentation and increases the Bcl-2 expression in human neuroblastoma, SH-SY5Y cells, through different mechanisms | Q41258866 | ||
| Amphotericin B: a novel class of antiscrapie drugs | Q41262896 | ||
| Aminoadamantanes as NMDA receptor antagonists and antiparkinsonian agents--preclinical studies. | Q41509275 | ||
| BCL-2 blocks glutamate toxicity in neural cell lines | Q41532133 | ||
| Excitotoxic mechanisms of neurodegeneration in transmissible spongiform encephalopathies | Q41643134 | ||
| The spectrum of transmissible spongiform encephalopathies | Q41693881 | ||
| Flupirtine, a nonopioid centrally acting analgesic, acts as an NMDA antagonist | Q41724627 | ||
| Cellular isoform of the scrapie agent protein participates in lymphocyte activation | Q41737574 | ||
| Mode of antinociceptive action of flupirtine in the rat. | Q41905541 | ||
| Sulphated glycosaminoglycans prevent the neurotoxicity of a human prion protein fragment | Q41987801 | ||
| Activation effects of a prion protein fragment [PrP-(106-126)] on human leucocytes | Q42124076 | ||
| Human keratinocytes express cellular prion-related protein in vitro and during inflammatory skin diseases | Q42463820 | ||
| Effect of the triaminopyridine flupirtine on calcium uptake, membrane potential and ATP synthesis in rat heart mitochondria. | Q43181843 | ||
| Determination of 14-3-3 protein levels in cerebrospinal fluid from Creutzfeldt-Jakob patients by a highly sensitive capture assay | Q43546837 | ||
| Creutzfeldt-Jakob disease: clinical features, epidemiology and tests | Q44296790 | ||
| Prion protein peptides induce alpha-helix to beta-sheet conformational transitions | Q44458369 | ||
| Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent | Q44592404 | ||
| Overexpression of Bcl-2 with herpes simplex virus vectors protects CNS neurons against neurological insults in vitro and in vivo | Q45772275 | ||
| The assay development of a molecular marker for transmissible spongiform encephalopathies. | Q45930864 | ||
| Memantine prevents HIV coat protein-induced neuronal injury in vitro | Q45976515 | ||
| P433 | issue | 2-3 | |
| P304 | page(s) | 193-218 | |
| P577 | publication date | 2000-07-01 | |
| P1433 | published in | Mechanisms of Ageing and Development | Q1839797 |
| P1476 | title | Novel approaches in diagnosis and therapy of Creutzfeldt-Jakob disease | |
| P478 | volume | 116 |
| Q34405540 | 14-3-3 proteins; bringing new definitions to scaffolding |
| Q43244743 | Anti-apoptotic effect of memantine against staurosporine- and low-potassium-induced cell death in cerebellar granule cells: a development-dependent effect |
| Q44588379 | Congo red analogues as potential anti-prion agents |
| Q37372476 | Copy number gain and oncogenic activity of YWHAZ/14-3-3zeta in head and neck squamous cell carcinoma |
| Q40093984 | Cyclodextrins inhibit replication of scrapie prion protein in cell culture. |
| Q43546837 | Determination of 14-3-3 protein levels in cerebrospinal fluid from Creutzfeldt-Jakob patients by a highly sensitive capture assay |
| Q36129188 | Evidence for inhibitory effects of flupirtine, a centrally acting analgesic, on delayed rectifier k(+) currents in motor neuron-like cells. |
| Q34625274 | Experimental treatments for human transmissible spongiform encephalopathies: is there a role for pentosan polysulfate? |
| Q34121060 | Flupirtine blocks apoptosis in batten patient lymphoblasts and in human postmitotic CLN3- and CLN2-deficient neurons |
| Q34322776 | Flupirtine, a re-discovered drug, revisited |
| Q36099134 | Mechanistic insights into the cure of prion disease by novel antiprion compounds |
| Q30490604 | Pharmacodynamics of memantine: an update |
| Q34701024 | Potassium channels: gene family, therapeutic relevance, high-throughput screening technologies and drug discovery. |
| Q46041482 | Protective effect of memantine against Doxorubicin toxicity in primary neuronal cell cultures: influence a development stage |
| Q33830151 | Redox control of prion and disease pathogenesis |
| Q37353880 | Small-molecule theranostic probes: a promising future in neurodegenerative diseases. |
| Q35122351 | Therapeutic approaches to prion diseases. |
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