Cellular and molecular mechanisms of bone remodeling.

scientific article

Cellular and molecular mechanisms of bone remodeling. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1074/JBC.R109.041087
P932PMC publication ID2919071
P698PubMed publication ID20501658

P50authorNicola C PartridgeQ55835077
P2093author name stringLiza J Raggatt
P2860cites workEssential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1Q24300916
Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activationQ24311588
Osteoprotegerin: a novel secreted protein involved in the regulation of bone densityQ24313918
Sclerostin is an osteocyte-expressed negative regulator of bone formation, but not a classical BMP antagonistQ24646652
Osteoimmunology: interactions of the bone and immune systemQ24655113
Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone developmentQ28119185
The microphthalmia transcription factor regulates expression of the tartrate-resistant acid phosphatase gene during terminal differentiation of osteoclastsQ28140929
Bone resorption by osteoclastsQ28145169
Spatial distribution of Bax and Bcl-2 in osteocytes after bone fatigue: complementary roles in bone remodeling regulation?Q28217341
Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signalingQ28240767
Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostinQ28261537
Megakaryocyte-osteoblast interaction revealed in mice deficient in transcription factors GATA-1 and NF-E2Q28585601
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesisQ28589430
Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblastsQ29547605
Genetic regulation of osteoclast development and functionQ29617421
Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclastsQ29618116
A physical mechanism for coupling bone resorption and formation in adult human bone.Q30485638
A three-dimensional distribution of osteocyte processes revealed by the combination of confocal laser scanning microscopy and differential interference contrast microscopyQ30653079
A G protein-linked receptor for parathyroid hormone and parathyroid hormone-related peptideQ31035948
The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption.Q33823576
Mice lacking beta3 integrins are osteosclerotic because of dysfunctional osteoclastsQ33939357
Parathyroid hormone-dependent signaling pathways regulating genes in bone cells.Q34508386
Transcriptional control of skeletogenesisQ34820209
Concerted regulation of inorganic pyrophosphate and osteopontin by akp2, enpp1, and ank: an integrated model of the pathogenesis of mineralization disordersQ35097443
Multiple signaling pathways converge on the Cbfa1/Runx2 transcription factor to regulate osteoblast differentiationQ35210378
B cells and T cells are critical for the preservation of bone homeostasis and attainment of peak bone mass in vivoQ35804512
Osteoclast-derived activity in the coupling of bone formation to resorption.Q36032429
Commitment and differentiation of osteoclast precursor cells by the sequential expression of c-Fms and receptor activator of nuclear factor kappaB (RANK) receptorsQ36375584
Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient miceQ36791739
Dissociation between bone resorption and bone formation in osteopenic transgenic miceQ36800774
Osteocytes as dynamic multifunctional cellsQ36889712
Osteitis fibrosa is mediated by Platelet-Derived Growth Factor-A via a phosphoinositide 3-kinase-dependent signaling pathway in a rat model for chronic hyperparathyroidismQ36976360
Regulation of bone formation by osteoclasts involves Wnt/BMP signaling and the chemokine sphingosine-1-phosphate.Q37015968
T cells: unexpected players in the bone loss induced by estrogen deficiency and in basal bone homeostasisQ37033722
Identification of cell cycle-arrested quiescent osteoclast precursors in vivoQ37124343
Metalloproteinase expression in monocytes and macrophages and its relationship to atherosclerotic plaque instabilityQ37261160
Osteal macrophages: a new twist on coupling during bone dynamicsQ37286721
TGF-beta1-induced migration of bone mesenchymal stem cells couples bone resorption with formationQ37307155
Differentiation and heterogeneity in the mononuclear phagocyte systemQ37349749
Colony-stimulating factor-1 induces cytoskeletal reorganization and c-src-dependent tyrosine phosphorylation of selected cellular proteins in rodent osteoclastsQ37374745
Parathyroid hormone stimulates osteoblastic expression of MCP-1 to recruit and increase the fusion of pre/osteoclastsQ40095819
Osteocytes inhibit osteoclastic bone resorption through transforming growth factor-beta: enhancement by estrogenQ40744910
The expression of osteoprotegerin and RANK ligand and the support of osteoclast formation by stromal-osteoblast lineage cells is developmentally regulatedQ40838648
Osteopetrosis in mice lacking haematopoietic transcription factor PU.1.Q41121255
A three-dimensional ultrastructural study of osteoid-osteocytes in the tibia of chick embryos.Q41476335
The ligand for osteoprotegerin (OPGL) directly activates mature osteoclasts.Q41649459
Eos, MITF, and PU.1 recruit corepressors to osteoclast-specific genes in committed myeloid progenitorsQ41842422
Hormonal regulation of the production of collagenase and a collagenase inhibitor activity by rat osteogenic sarcoma cellsQ42509736
Unique coexpression in osteoblasts of broadly expressed genes accounts for the spatial restriction of ECM mineralization to boneQ42732135
Mechanical strain induces collagenase-3 (MMP-13) expression in MC3T3-E1 osteoblastic cellsQ42830345
The bone lining cell: its role in cleaning Howship's lacunae and initiating bone formation.Q43842252
Osteal tissue macrophages are intercalated throughout human and mouse bone lining tissues and regulate osteoblast function in vitro and in vivoQ46277067
Osteopontin is strongly expressed by alveolar macrophages in the lungs of acute respiratory distress syndromeQ47900564
Osteocyte apoptosis is induced by weightlessness in mice and precedes osteoclast recruitment and bone loss.Q53628612
PTH/PTHrP receptor expression on osteoblasts and osteocytes but not resorbing bone surfaces in growing rats.Q54156212
Bidirectional ephrinB2-EphB4 signaling controls bone homeostasisQ57675131
c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodelingQ58326943
The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor geneQ59092154
Macrophages in T and B cell compartments and other tissue macrophages recognized by monoclonal antibody MOMA-2. An immunohistochemical studyQ68215594
An electron-microscopic study of the bone-remodeling sequence in the ratQ70424503
Alkaline phosphatase expression during monocyte differentiation. Overlapping markers as a link between monocytic cells, dendritic cells, osteoclasts and osteoblastsQ73952564
Catabolic effects of continuous human PTH (1--38) in vivo is associated with sustained stimulation of RANKL and inhibition of osteoprotegerin and gene-associated bone formationQ74411385
Cancellous bone remodeling occurs in specialized compartments lined by cells expressing osteoblastic markersQ74488802
Identification of multiple osteoclast precursor populations in murine bone marrowQ81628327
P433issue33
P407language of work or nameEnglishQ1860
P304page(s)25103-25108
P577publication date2010-05-25
P1433published inJournal of Biological ChemistryQ867727
P1476titleCellular and molecular mechanisms of bone remodeling
P478volume285

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Q38736047Stem cells applications in bone and tooth repair and regeneration: New insights, tools, and hopes
Q33619640Stress and Alterations in Bones: An Interdisciplinary Perspective
Q96305153Strontium-substituted sub-micron bioactive glasses inhibit ostoclastogenesis through suppression of RANKL-induced signaling pathway
Q55313392Substance P modulates bone remodeling properties of murine osteoblasts and osteoclasts.
Q33766770Succinate and its G-protein-coupled receptor stimulates osteoclastogenesis.
Q48209434Syringic acid, a phenolic acid, promotes osteoblast differentiation by stimulation of Runx2 expression and targeting of Smad7 by miR-21 in mouse mesenchymal stem cells
Q35097782Systemic infusion of mesenchymal stem cells improves cell-based bone regeneration via upregulation of regulatory T cells
Q37066493TREM2 and β-catenin regulate bone homeostasis by controlling the rate of osteoclastogenesis
Q38970585Targeting the Bone Marrow Microenvironment.
Q90216390The Antagonist of Retinoic Acid Receptor α, ER-50891 Antagonizes the Inhibitive Effect of All-Trans Retinoic Acid and Rescues Bone Morphogenetic Protein 2-Induced Osteoblastogenic Differentiation
Q92712185The Autophagy in Osteoimmonology: Self-Eating, Maintenance, and Beyond
Q92081389The Bone Extracellular Matrix as an Ideal Milieu for Cancer Cell Metastases
Q47224539The Components of Bone and What They Can Teach Us about Regeneration
Q35674722The Effect of OSM on MC3T3-E1 Osteoblastic Cells in Simulated Microgravity with Radiation
Q37352889The Effects of Dietary Supplements of Calcium, Vitamin D and Estrogen Hormone on Serum Levels of OPG and RANKL Cytokines and their Relationship with Increased Bone Density in Rats.
Q88907245The Growth Proliferation, Apoptotic Prevention, and Differentiation Induction of the Gelatin Hydrolysates from Three Sources to Human Fetal Osteoblasts (hFOB 1.19 Cells)
Q97557237The Ins and Outs of Cathepsins: Physiological Function and Role in Disease Management
Q53211469The Protective Effects of Alisol A 24-Acetate from Alisma canaliculatum on Ovariectomy Induced Bone Loss in Vivo.
Q26783615The Role of Hedgehog Signaling in Tumor Induced Bone Disease
Q39120074The Role of TGFβ in Bone-Muscle Crosstalk
Q38940135The botanical molecule p-hydroxycinnamic acid as a new osteogenic agent: insight into the treatment of cancer bone metastases
Q38545213The dynamic skeleton
Q46851946The effect of etidronate on the periodontium of ovariectomized rats
Q33918020The effects of proteasome inhibitors on bone remodeling in multiple myeloma
Q88815672The impact of age on radium-223 distribution and an evaluation of molecular imaging surrogates
Q36007649The influence of calcitonin gene-related peptide on markers of bone metabolism in MG-63 osteoblast-like cells co-cultured with THP-1 macrophage-like cells under virtually osteolytic conditions
Q41683326The inhibitors of cyclin-dependent kinases and GSK-3β enhance osteoclastogenesis
Q35583735The mammalian lectin galectin-8 induces RANKL expression, osteoclastogenesis, and bone mass reduction in mice
Q33875419The p38α MAPK function in osteoprecursors is required for bone formation and bone homeostasis in adult mice
Q51790755The p38α MAPK positively regulates osteoblast function and postnatal bone acquisition.
Q33565236The role of DNA methylation in common skeletal disorders
Q36111285The role of RANK ligand/osteoprotegerin in rheumatoid arthritis
Q37585395The role of midkine in skeletal remodelling
Q38181384The role of regucalcin in bone homeostasis: involvement as a novel cytokine
Q38602606Thyroid diseases and bone health
Q89107012Tissue engineered bone mimetics to study bone disorders ex vivo: Role of bioinspired materials
Q30725567Total water, phosphorus relaxation and inter-atomic organic to inorganic interface are new determinants of trabecular bone integrity
Q47219376Trabecular mapping: Leveraging geometric morphometrics for analyses of trabecular structure
Q50104779Transforming growth factor-β in stem cells and tissue homeostasis
Q57462447Ubiquitin-specific protease USP34 controls osteogenic differentiation and bone formation by regulating BMP2 signaling
Q48198849Upconversion Nanocarriers Encapsulated with Photoactivatable Ru Complexes for Near-Infrared Light-Regulated Enzyme Activity
Q93196080Uptake of osteoblast-derived extracellular vesicles promotes the differentiation of osteoclasts in the zebrafish scale
Q38648767Ursolic Acid--A Pentacyclic Triterpenoid with a Wide Spectrum of Pharmacological Activities
Q64282246Vitamin A decreases the anabolic bone response to mechanical loading by suppressing bone formation
Q37582330β-Caryophyllene promotes osteoblastic mineralization, and suppresses osteoclastogenesis and adipogenesis in mouse bone marrow cultures in vitro

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