review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1016/S0891-5849(00)00417-2 |
P698 | PubMed publication ID | 11084284 |
P50 | author | Mary-Ellen Harper | Q39497756 |
P2093 | author name string | R Weindruch | |
J J Ramsey | |||
P2860 | cites work | BMCP1, a novel mitochondrial carrier with high expression in the central nervous system of humans and rodents, and respiration uncoupling activity in recombinant yeast | Q22008535 |
UCP4, a novel brain-specific mitochondrial protein that reduces membrane potential in mammalian cells | Q22008783 | ||
Uncoupling protein-3: a new member of the mitochondrial carrier family with tissue-specific expression | Q24309291 | ||
UCP3: an uncoupling protein homologue expressed preferentially and abundantly in skeletal muscle and brown adipose tissue | Q24312228 | ||
Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia | Q24324798 | ||
The aging process | Q24616537 | ||
Aging: a theory based on free radical and radiation chemistry | Q27860549 | ||
Cloning and characterization of the 5' flanking region of the human uncoupling protein 3 (UCP3) gene | Q28144070 | ||
Cloning and characterization of an uncoupling protein homolog: a potential molecular mediator of human thermogenesis | Q28236890 | ||
Adaptive reduction in basal metabolic rate in response to food deprivation in humans: a role for feedback signals from fat stores | Q28282145 | ||
The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen | Q29616357 | ||
Oxidative stress, caloric restriction, and aging | Q29618229 | ||
Exercise training-induced alterations in skeletal muscle antioxidant capacity: a brief review | Q33693424 | ||
Seminars in medicine of the Beth Israel Deaconess Medical Center. Caloric intake and aging | Q33775761 | ||
Mitochondrial oxygen radical generation and leak: sites of production in states 4 and 3, organ specificity, and relation to aging and longevity | Q33832703 | ||
Effect of age and caloric restriction on DNA oxidative damage in different tissues of C57BL/6 mice | Q34320508 | ||
Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian species | Q34338013 | ||
Cellular energy utilization and molecular origin of standard metabolic rate in mammals | Q34433543 | ||
Regulation of mitochondrial protein turnover by thyroid hormone(s) | Q34663614 | ||
Evolution of energy metabolism. Proton permeability of the inner membrane of liver mitochondria is greater in a mammal than in a reptile | Q34781672 | ||
Exercise and food restriction in rats | Q35899496 | ||
Basal metabolic rate, fat-free mass, and body cell mass during energy restriction | Q35966256 | ||
Biochemical and stereological analysis of rat liver mitochondria in different thyroid states | Q36199636 | ||
The leaks and slips of bioenergetic membranes | Q36380004 | ||
Calorie restriction lowers body temperature in rhesus monkeys, consistent with a postulated anti-aging mechanism in rodents | Q37631308 | ||
Cellular energy metabolism and regulation | Q37747370 | ||
Oxidative muscular injury and its relevance to hyperthyroidism | Q37923919 | ||
Changes in liver and gastrointestinal tract energy demands in response to physiological workload in ruminants | Q37930742 | ||
Superoxide anion radical production in different animal species | Q38293228 | ||
Lipids and thyroid hormones | Q39578221 | ||
Changes in the Erythrocyte Sodium Pump with Age | Q39803512 | ||
Assessment of interrelationships among levels of intake and production, organ size and fasting heat production in growing animals | Q39830222 | ||
The relation of metabolic rate to body weight and organ size | Q40011792 | ||
Age estimation and longevity in reptiles | Q40633128 | ||
How diet influences the aging process of the rat. | Q40714625 | ||
FRAR course on laboratory approaches to aging. The comparative perspective and choice of animal models in aging research. | Q40809329 | ||
Regulation of energy expenditure in aging humans | Q40853659 | ||
Antiaging action of caloric restriction: endocrine and metabolic aspects | Q40958703 | ||
Uncoupling protein-3 expression in rodent skeletal muscle is modulated by food intake but not by changes in environmental temperature | Q41067789 | ||
Effects of fasting, refeeding, and fasting with T3 administration on Na-K,ATPase in rat skeletal muscle | Q41085610 | ||
Age-related changes in rates of protein synthesis and degradation in rat tissues. | Q41166913 | ||
The contribution of the leak of protons across the mitochondrial inner membrane to standard metabolic rate | Q41201367 | ||
No major thermogenic role for (Na+ + K+)-dependent adenosine triphosphatase apparent in hepatocytes from hyperthyroid rats | Q41553460 | ||
Reactive oxygen species, mitochondria, apoptosis and aging. | Q41601406 | ||
Aging, protein requirements, and protein turnover | Q41606661 | ||
Variables affecting measurement of human red cell Na+,K+ATPase activity: technical factors, feeding, aging | Q42447382 | ||
Protein turnover and growth in the whole body, liver and kidney of the rat from the foetus to senility | Q42867813 | ||
Thyroid hormones and muscle protein turnover. The effect of thyroid-hormone deficiency and replacement in thryoidectomized and hypophysectomized rats | Q42883731 | ||
Effects of caloric restriction on skeletal muscle mitochondrial proton leak in aging rats | Q43544613 | ||
Influence of plane of nutrition on body composition, organ size and energy utilization of Sprague-Dawley rats | Q43943824 | ||
Dietary restriction and aging: the initiation of a primate study | Q44048396 | ||
The effects of aging and chronic dietary restriction on whole body growth and protein turnover in the rat. | Q44181614 | ||
Effect of reduced dietary intake on energy expenditure, protein turnover, and glucose cycling in man. | Q44366495 | ||
Whole body protein turnover in aging man. | Q44431357 | ||
Comparison of the effect of a mitochondrial uncoupler, 2,4-dinitrophenol and adrenaline on oxygen radical production in the isolated perfused rat liver | Q44499306 | ||
Energy utilization and organ mass of Targhee sheep selected for rate and efficiency of gain and receiving high and low planes of nutrition | Q44725489 | ||
Singlet oxygen-induced inhibition of cardiac sarcolemmal Na+K(+)-ATPase | Q44896105 | ||
Aging and ATPase activities in rat jejunum | Q44898922 | ||
Repetitive weight loss and weight regain: effects on weight reduction, resting metabolic rate, and lipolytic activity before and after exercise and/or diet treatment | Q47173772 | ||
Visceral organ size and hepatocyte metabolic activity in fed and fasted rats | Q47176389 | ||
Effects of plane of nutrition on organ size and fasting heat production in genetically obese and lean pigs | Q47251317 | ||
Effects of plane of nutrition on organ size and fasting heat production in pigs | Q47265984 | ||
Physiological adaptations to a weight-loss dietary regimen and exercise programs in women | Q47306299 | ||
Changes in Energy Expenditure Resulting from Altered Body Weight | Q47357419 | ||
Severe vs moderate energy restriction with and without exercise in the treatment of obesity: efficiency of weight loss | Q47398996 | ||
Animal longevity and protein turnover rate | Q47864143 | ||
The proton permeability of the inner membrane of liver mitochondria from ectothermic and endothermic vertebrates and from obese rats: correlations with standard metabolic rate and phospholipid fatty acid composition. | Q47965601 | ||
Effect of aging on the activities of acetylcholinesterase, Na+,K(+)-ATPase and Mg(2+)-ATPase in rat pituitary and hypothalamus | Q47997599 | ||
Starvation-induced changes in metabolic rate, blood flow, and regional energy expenditure in rats | Q48301706 | ||
Localization at complex I and mechanism of the higher free radical production of brain nonsynaptic mitochondria in the short-lived rat than in the longevous pigeon | Q48398051 | ||
Aging: effects on sodium- and potassium-activated adenosine triphosphatase activity and ouabain binding sites in rat brain | Q48477121 | ||
An allometric comparison of the mitochondria of mammalian and reptilian tissues: the implications for the evolution of endothermy | Q48572621 | ||
Mortality rate and longevity of food-restricted exercising male rats: a reevaluation | Q48767951 | ||
Does food restriction retard aging by reducing metabolic rate? | Q48829536 | ||
Effect of chronic food restriction in aging rats. I. Liver subcellular membranes | Q48922686 | ||
Changes in protein turnover and growth of the rat lung in response to ageing and long-term dietary restriction | Q48945972 | ||
Dietary omega 6 fatty acids and the effects of hyperthyroidism in mice | Q49172184 | ||
Long-term dietary restriction in older-aged rhesus monkeys: effects on insulin resistance | Q49328279 | ||
Whole body protein turnover in chronically undernourished individuals | Q50120563 | ||
Dietary restriction of adult male rhesus monkeys: design, methodology, and preliminary findings from the first year of study | Q50128241 | ||
Whole-body protein turnover in the healthy elderly. | Q50931505 | ||
Lymphocyte Na,K-ATPase is reduced in aged people. | Q51614970 | ||
Long-term food restriction depresses serum thyroid hormone concentrations in the rat. | Q51616529 | ||
Controlled trial of the metabolic effects of a very-low-calorie diet: short- and long-term effects. | Q51616911 | ||
The effect of chronic and acute dietary restriction on the growth and protein turnover of fast and slow types of rat skeletal muscle. | Q52264065 | ||
Visceral oxygen consumption during chronic feed restriction and realimentation in sheep | Q52349880 | ||
Hydrogen peroxide production by liver mitochondria in different species. | Q52449073 | ||
Adaptation of energy metabolism to undernutrition in ewes. Contribution of portal-drained viscera, liver and hindquarters. | Q52915295 | ||
Hyperthyroidism stimulates mitochondrial proton leak and ATP turnover in rat hepatocytes but does not change the overall kinetics of substrate oxidation reactions. | Q55065329 | ||
A study of the prognostic respiratory markers of sustained weight loss in obese subjects after 28 days on VLCD | Q58419887 | ||
Body mass dependence of H+ leak in mitochondria and its relevance to metabolic rate | Q59066240 | ||
A Paradigm of Experimentally Induced Mild Hyperthyroidism: Effects on Nitrogen Balance, Body Composition, and Energy Expenditure in Healthy Young Men | Q61985346 | ||
Vascular tissue (Na,K)ATPase activity and aging in the F344 rat. | Q64891894 | ||
Effect of Age on Red Cell Membrane Sodium-potassium Dependent Adenosine Triphosphatase (na +-k+ Atpase) Activity in Healthy Men | Q67246792 | ||
Growth, body composition, and visceral organ mass and metabolism in lambs during and after metabolizable protein or net energy restrictions | Q67976570 | ||
Age-related changes in whole-body amino acid kinetics and protein turnover in rats | Q68044035 | ||
Effects of caloric restriction and aging on erythrocyte membrane Ca2+-ATPase activity in specific pathogen-free Fischer 344 rats | Q68247072 | ||
Basal metabolic rate, body composition and whole-body protein turnover in Indian men with differing nutritional status | Q68256425 | ||
Synthesis of insulin-dependent activator of hepatocyte plasmatic membrane Na,K-ATPase decreases in aging | Q68265652 | ||
Synaptic aging as revealed by changes in membrane potential and decreased activity of Na+,K(+)-ATPase | Q68448711 | ||
The influence of chronic dietary intervention on protein turnover and growth of the diaphragm and extensor digitorum longus muscles of the rat | Q69057054 | ||
Energy expenditure associated with sodium/potassium transport and protein synthesis in skeletal muscle and isolated hepatocytes from hyperthyroid sheep | Q69362017 | ||
The biological basis of maintenance and its relevance to assessing responses to nutrients | Q69600267 | ||
Effect of a high-protein, very-low-calorie diet on resting metabolism, thyroid hormones, and energy expenditure of obese middle-aged women | Q69740757 | ||
Effect of level of nutrition on splanchnic blood flow and oxygen consumption in sheep | Q69745240 | ||
Energy expenditure before and during energy restriction in obese patients | Q70081827 | ||
Decrease of lymphocyte (Na+,K+)ATP-ase activity in aged people | Q70119533 | ||
Effects of a very-low-calorie diet and physical-training regimens on body composition and resting metabolic rate in obese females | Q70210152 | ||
Skeletal muscle and whole body protein turnover in thyroid disease | Q70387459 | ||
Maintenance energy requirements during lactation in rats | Q70455579 | ||
Energy restriction reduces metabolic rate in adult male Fisher-344 rats | Q70531891 | ||
Modulation of membrane phospholipid fatty acid composition by age and food restriction | Q70578417 | ||
Manipulating metabolic parameters to improve growth rate and milk secretion | Q70659174 | ||
Pituitary-thyroid activity and longevity in neonatally thyroxine-treated rats | Q71077199 | ||
Effect of experimental hyperthyroidism on protein turnover in skeletal and cardiac muscle | Q71337585 | ||
Proton leak and control of oxidative phosphorylation in perfused, resting rat skeletal muscle | Q71420444 | ||
Contribution of mitochondrial proton leak to skeletal muscle respiration and to standard metabolic rate | Q71738047 | ||
Differential effects of plane of protein or energy nutrition on visceral organs and hormones in lambs1 | Q72054676 | ||
Characteristics of mitochondrial proton leak and control of oxidative phosphorylation in the major oxygen-consuming tissues of the rat | Q72364841 | ||
Effect of an energy-restrictive diet, with or without exercise, on lean tissue mass, resting metabolic rate, cardiovascular risk factors, and bone in overweight postmenopausal women | Q72892977 | ||
Physical activity as a factor in the action of dietary restriction on aging: effects in Fischer 344 rats | Q73401822 | ||
A role for uncoupling protein-2 as a regulator of mitochondrial hydrogen peroxide generation | Q73626811 | ||
Effects of diet and exercise on energy expenditure in postmenopausal women | Q73760799 | ||
Effect of thyroid state on lipid peroxidation, antioxidant defences, and susceptibility to oxidative stress in rat tissues | Q73923926 | ||
Birds as Models of Aging in Biomedical Research | Q74440416 | ||
Long-term calorie restriction reduces energy expenditure in aging monkeys | Q74457542 | ||
Mitochondrial proton leak and superoxide generation: an hypothesis | Q74521456 | ||
Expression of uncoupling protein-3 and mitochondrial activity in the transition from hypothyroid to hyperthyroid state in rat skeletal muscle | Q74528007 | ||
Contribution of mitochondrial proton leak to respiration rate in working skeletal muscle and liver and to SMR | Q74590837 | ||
P433 | issue | 10 | |
P304 | page(s) | 946-968 | |
P577 | publication date | 2000-11-01 | |
P1433 | published in | Free Radical Biology and Medicine | Q5500023 |
P1476 | title | Restriction of energy intake, energy expenditure, and aging | |
P478 | volume | 29 |
Q28484850 | 3,5-Diiodo-L-thyronine administration to hypothyroid rats rapidly enhances fatty acid oxidation rate and bioenergetic parameters in liver cells |
Q33906121 | A general life history theory for effects of caloric restriction on health maintenance |
Q83465005 | A general model for ontogenetic growth under food restriction |
Q44260221 | A low molecular weight antioxidant decreases weight and lowers tumor incidence |
Q81110366 | A proposed mechanism for the lowering of mitochondrial electron leak by caloric restriction |
Q51418867 | Acute administration of 3,5-diiodo-L-thyronine to hypothyroid rats stimulates bioenergetic parameters in liver mitochondria. |
Q35966046 | Ageing, oxidative stress, and mitochondrial uncoupling. |
Q42451639 | Age‐related changes in the metabolism and body composition of three dog breeds and their relationship to life expectancy |
Q34688131 | Aging is a deprivation syndrome driven by a germ-soma conflict |
Q33954183 | Caloric restriction and the aging process: a critique |
Q51603217 | Caloric restriction in lean and obese strains of laboratory rat: effects on body composition, metabolism, growth and overall health. |
Q33535799 | Caloric restriction shortens lifespan through an increase in lipid peroxidation, inflammation and apoptosis in the G93A mouse, an animal model of ALS. |
Q28763406 | Calorie restriction increases muscle mitochondrial biogenesis in healthy humans |
Q24541443 | Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency |
Q33206142 | Cloning and identification of hepatocellular carcinoma down-regulated mitochondrial carrier protein, a novel liver-specific uncoupling protein |
Q36952404 | Considerations on temperature, longevity and aging |
Q36434968 | Control of energy balance in relation to energy intake and energy expenditure in animals and man: an ecological perspective |
Q50102206 | Cross-species comparison of proteome turnover kinetics |
Q45220595 | Dexamethasone impairs muscle energetics, studied by (31)P NMR, in rats. |
Q33899468 | Dietary approaches to epilepsy treatment: old and new options on the menu |
Q35221395 | Dietary fat and aging modulate apoptotic signaling in liver of calorie-restricted mice |
Q42444722 | Dietary restriction and beta-cell sensitivity to glucose in adult male rhesus monkeys |
Q35527234 | Do altered energy metabolism or spontaneous locomotion 'mediate' decelerated senescence? |
Q28564376 | Down-regulation of the cardiac sarcoplasmic reticulum ryanodine channel in severely food-restricted rats |
Q37217429 | Effect of 6-month calorie restriction on biomarkers of longevity, metabolic adaptation, and oxidative stress in overweight individuals: a randomized controlled trial |
Q37039107 | Effect of aging, caloric restriction, and uncoupling protein 3 (UCP3) on mitochondrial proton leak in mice |
Q33887533 | Effect of indigenous herbs on growth, blood metabolites and carcass characteristics in the late fattening period of hanwoo steers |
Q36102928 | Effect of long-term caloric restriction on oxygen consumption and body temperature in two different strains of mice |
Q43747230 | Effects of 12 Months of Caloric Restriction on Muscle Mitochondrial Function in Healthy Individuals |
Q35713626 | Effects of age and caloric restriction on mitochondrial protein oxidative damage in mice |
Q45183235 | Effects of phentermine and phenformin on biomarkers of aging in rats |
Q33636335 | Energy expenditure and aging |
Q53649006 | Exercise, body mass index, caloric intake, and cardiovascular mortality. |
Q44004658 | Exercise-induced oxidative stress in older adults as a function of habitual activity level |
Q44392594 | Food restriction attenuates blood lipid peroxidation in carbon tetrachloride-intoxicated rats |
Q45969593 | Food restriction promotes downregulation of myocardial L-type Ca2+ channels. |
Q34079690 | Genetic dissection of dietary restriction in mice supports the metabolic efficiency model of life extension |
Q90580174 | Greater skeletal muscle oxidative capacity is associated with higher resting metabolic rate: results from the Baltimore Longitudinal Study of Aging |
Q30494859 | Honoring Clive McCay and 75 years of calorie restriction research |
Q37264286 | Individual variation in macronutrient regulation measured by proton magnetic resonance spectroscopy of human plasma. |
Q42493468 | Influence of intensity of food restriction on skeletal muscle mitochondrial energy metabolism in rats |
Q35173320 | Interaction of growth hormone receptor/binding protein gene disruption and caloric restriction for insulin sensitivity and attenuated aging. |
Q34062800 | Intrinsic aerobic capacity impacts susceptibility to acute high-fat diet-induced hepatic steatosis |
Q36192493 | Laboratory findings of caloric restriction in rodents and primates. |
Q43176943 | Life span extension in mice by food restriction depends on an energy imbalance |
Q47799207 | Long-term caloric restriction increases UCP3 content but decreases proton leak and reactive oxygen species production in rat skeletal muscle mitochondria |
Q45161623 | Long-term calorie restriction reduces proton leak and hydrogen peroxide production in liver mitochondria |
Q37306243 | Long-term dietary restriction influences plasma ghrelin and GOAT mRNA level in rats |
Q42710645 | Mechanisms of muscular electrophysiological and mitochondrial dysfunction following exposure to malathion, an organophosphorus pesticide |
Q36713728 | Mechanisms underlying caloric restriction and lifespan regulation: implications for vascular aging. |
Q36633913 | Metabolic reprogramming in dietary restriction |
Q24647414 | Metabolic shifts due to long-term caloric restriction revealed in nonhuman primates |
Q82514835 | Mitochondrial energetics in liver and skeletal muscle after energy restriction in young rats |
Q42411402 | Mitochondrial energy metabolism in a model of undernutrition induced by dexamethasone |
Q44217937 | Modulations by dietary restriction on antioxidant enzymes and lipid peroxidation in developing mice |
Q34801651 | Molecular mechanisms linking calorie restriction and longevity |
Q46382518 | Nutrition modulation of human aging: The calorie restriction paradigm |
Q39144678 | Nutrition, metabolism, and targeting aging in nonhuman primates |
Q44068708 | Oxidative damage increases with age in a canine model of human brain aging |
Q51392997 | Pre-operative dietary restriction is feasible in live-kidney donors. |
Q50170151 | Predicting the effects of body fatness on food intake and performance of sheep. |
Q60922005 | Preoperative short-term fasting protects liver injury in patients undergoing hepatectomy |
Q44684766 | Proton leak and hydrogen peroxide production in liver mitochondria from energy-restricted rats |
Q37440086 | Reduced hepatic mitochondrial respiration following acute high-fat diet is prevented by PGC-1α overexpression. |
Q42011059 | Relationship between Liver Mitochondrial Respiration and Proton Leak in Low and High RFI Steers from Two Lineages of RFI Angus Bulls |
Q28577981 | Severe food restriction induces myocardial dysfunction related to SERCA2 activity |
Q47851494 | Sex-related differences in energy balance in response to caloric restriction. |
Q33566529 | The effects of graded levels of calorie restriction: VIII. Impact of short term calorie and protein restriction on basal metabolic rate in the C57BL/6 mouse |
Q38611320 | The embedded tumour: host physiology is important for the evaluation of tumour growth |
Q35105507 | The evolution of the control of food intake |
Q36012249 | The influence of dietary fat source on liver and skeletal muscle mitochondrial modifications and lifespan changes in calorie-restricted mice |
Q36467364 | The influence of dietary lipid composition on liver mitochondria from mice following 1 month of calorie restriction |
Q36796224 | The influence of dietary lipid composition on skeletal muscle mitochondria from mice following 1 month of calorie restriction |
Q34069418 | The influence of dietary lipid composition on skeletal muscle mitochondria from mice following eight months of calorie restriction |
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