Effect of aging, caloric restriction, and uncoupling protein 3 (UCP3) on mitochondrial proton leak in mice

scientific article published on 30 September 2008

Effect of aging, caloric restriction, and uncoupling protein 3 (UCP3) on mitochondrial proton leak in mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.EXGER.2008.09.010
P8608Fatcat IDrelease_dsssmrw5ojbmfhuurikl7thbcu
P932PMC publication ID2614627
P698PubMed publication ID18852040
P5875ResearchGate publication ID23316391

P2093author name stringJon J Ramsey
Kevork Hagopian
Craig Warden
Danny K Asami
Barbara A Horwitz
Roger B McDonald
Aileen Hsiao
David Warman
P2860cites workAging: a theory based on free radical and radiation chemistryQ27860549
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The basal proton conductance of skeletal muscle mitochondria from transgenic mice overexpressing or lacking uncoupling protein-3Q28513383
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The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygenQ29616357
Oxidative stress, caloric restriction, and agingQ29618229
Uncoupling proteins 2 and 3 are fundamental for mitochondrial Ca2+ uniportQ30580904
Living fast, dying when? The link between aging and energeticsQ33959448
Regulation analysis of energy metabolismQ34064222
Uncoupling to survive? The role of mitochondrial inefficiency in ageingQ34071511
Restriction of energy intake, energy expenditure, and aging.Q34085462
Effects of short- and medium-term calorie restriction on muscle mitochondrial proton leak and reactive oxygen species production.Q34291503
Cellular energy utilization and molecular origin of standard metabolic rate in mammalsQ34433543
Molecular mechanisms linking calorie restriction and longevityQ34801651
Mitochondrial uncoupling proteins--facts and fantasies.Q35761389
Mitochondrial H(+) leak and ROS generation: an odd coupleQ35979114
Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3.Q36228620
Putative function and physiological relevance of the mitochondrial uncoupling protein-3: involvement in fatty acid metabolism?Q36356286
Mitochondrial DNA mutations, energy metabolism and apoptosis in aging muscleQ36463506
Novel uncoupling proteinsQ37030116
Mitochondrial Ca2+, the secret behind the function of uncoupling proteins 2 and 3?Q37087727
Role of calcium ions in regulation of mammalian intramitochondrial metabolismQ37875647
Physiological increases in uncoupling protein 3 augment fatty acid oxidation and decrease reactive oxygen species production without uncoupling respiration in muscle cells.Q40392941
The causes and functions of mitochondrial proton leakQ40696613
Uncoupling: new approaches to an old problem of bioenergeticsQ41723090
Effects of caloric restriction on skeletal muscle mitochondrial proton leak in aging ratsQ43544613
Mitochondrial abnormalities are more frequent in muscles undergoing sarcopenia.Q43996752
Proton leak and hydrogen peroxide production in liver mitochondria from energy-restricted ratsQ44684766
Reduction of diet-induced obesity in transgenic mice overexpressing uncoupling protein 3 in skeletal muscleQ44691843
Uncoupled and surviving: individual mice with high metabolism have greater mitochondrial uncoupling and live longerQ44903080
Long-term calorie restriction reduces proton leak and hydrogen peroxide production in liver mitochondriaQ45161623
Lack of effect of caloric restriction on bioenergetics and reactive oxygen species production in intact rat hepatocytesQ46426002
Long-term caloric restriction increases UCP3 content but decreases proton leak and reactive oxygen species production in rat skeletal muscle mitochondriaQ47799207
The proton permeability of the inner membrane of liver mitochondria from ectothermic and endothermic vertebrates and from obese rats: correlations with standard metabolic rate and phospholipid fatty acid composition.Q47965601
Effect of caloric restriction on mitochondrial reactive oxygen species production and bioenergetics: reversal by insulinQ48953514
On the importance of fatty acid composition of membranes for aging.Q53864675
Microsomal lipid peroxidationQ67358293
Modulation of membrane phospholipid fatty acid composition by age and food restrictionQ70578417
Allometry of mitochondrial proton leak: influence of membrane surface area and fatty acid compositionQ71978404
Characteristics of mitochondrial proton leak and control of oxidative phosphorylation in the major oxygen-consuming tissues of the ratQ72364841
Uncoupling proteins-2 and 3 influence obesity and inflammation in transgenic miceQ73189686
Mitochondrial proton leak and superoxide generation: an hypothesisQ74521456
Age-related increase in mitochondrial proton leak and decrease in ATP turnover reactions in mouse hepatocytesQ74831594
Role of mitochondrial calcium transport in the control of substrate oxidationQ77327606
Protein carbonyl measurement by enzyme-linked immunosorbent assayQ77907840
P433issue12
P921main subjectmitochondrionQ39572
calorie restrictionQ1332886
P304page(s)1069-1076
P577publication date2008-09-30
P1433published inExperimental GerontologyQ15766996
P1476titleEffect of aging, caloric restriction, and uncoupling protein 3 (UCP3) on mitochondrial proton leak in mice
P478volume43

Reverse relations

cites work (P2860)
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