| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Martin Jastroch | Q63869059 |
| Martin D. Brand | Q39854778 | ||
| P2093 | author name string | Ajit S Divakaruni | |
| Vian Azzu | |||
| P2860 | cites work | Uncoupling protein-3: a new member of the mitochondrial carrier family with tissue-specific expression | Q24309291 |
| Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia | Q24324798 | ||
| Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells | Q24810302 | ||
| Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production | Q28139177 | ||
| Uncoupling proteins 2 and 3 interact with members of the 14.3.3 family | Q28143097 | ||
| Uncoupling protein 2: a novel player in neuroprotection | Q28189671 | ||
| Superoxide activates mitochondrial uncoupling proteins | Q28214829 | ||
| Genipin inhibits UCP2-mediated proton leak and acutely reverses obesity- and high glucose-induced beta cell dysfunction in isolated pancreatic islets | Q28244291 | ||
| Uncoupling protein-3 is a mediator of thermogenesis regulated by thyroid hormone, beta3-adrenergic agonists, and leptin | Q28249563 | ||
| Artifactual uncoupling by uncoupling protein 3 in yeast mitochondria at the concentrations found in mouse and rat skeletal-muscle mitochondria | Q28366431 | ||
| Lack of obesity and normal response to fasting and thyroid hormone in mice lacking uncoupling protein-3 | Q28506464 | ||
| Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese | Q28510931 | ||
| UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality | Q28513102 | ||
| The basal proton conductance of skeletal muscle mitochondria from transgenic mice overexpressing or lacking uncoupling protein-3 | Q28513383 | ||
| Synergy of fatty acid and reactive alkenal activation of proton conductance through uncoupling protein 1 in mitochondria | Q28565547 | ||
| Reduction of diet-induced obesity in transgenic mice overexpressing uncoupling protein 3 in skeletal muscle | Q44691843 | ||
| Alkylsulfonates activate the uncoupling protein UCP1: implications for the transport mechanism | Q44761636 | ||
| Native UCP1 displays simple competitive kinetics between the regulators purine nucleotides and fatty acids. | Q44945464 | ||
| Identification of a functioning mitochondrial uncoupling protein 1 in thymus | Q45254074 | ||
| Uncoupling protein 1 in fish uncovers an ancient evolutionary history of mammalian nonshivering thermogenesis | Q45345676 | ||
| UCP3 overexpression neutralizes oxidative stress rather than nitrosative stress in mouse myotubes | Q46187034 | ||
| Constitutive UCP3 overexpression at physiological levels increases mouse skeletal muscle capacity for fatty acid transport and oxidation | Q46425799 | ||
| Uncoupling protein-2 accumulates rapidly in the inner mitochondrial membrane during mitochondrial reactive oxygen stress in macrophages | Q46848901 | ||
| Reduced skeletal muscle uncoupling protein-3 content in prediabetic subjects and type 2 diabetic patients: restoration by rosiglitazone treatment | Q46872399 | ||
| Enhanced colon tumor induction in uncoupling protein-2 deficient mice is associated with NF-kappaB activation and oxidative stress. | Q46886077 | ||
| Brown adipose tissue specific lack of uncoupling protein 3 is associated with impaired cold tolerance and reduced transcript levels of metabolic genes | Q46911506 | ||
| Functional characterisation of UCP1 in the common carp: uncoupling activity in liver mitochondria and cold-induced expression in the brain | Q48132501 | ||
| Mitochondrial reactive oxygen species are required for hypothalamic glucose sensing. | Q48486223 | ||
| Regulation of UCP1 and UCP3 in arctic ground squirrels and relation with mitochondrial proton leak. | Q51496302 | ||
| Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity. | Q53531526 | ||
| Uncoupling Protein-2 Participates in Cellular Defense against Oxidative Stress in Clonal β-Cells | Q57672115 | ||
| Functional Relationship between MyoD and Peroxisome Proliferator-Activated Receptor-Dependent Regulatory Pathways in the Control of the Human Uncoupling Protein-3 Gene Transcription | Q60636891 | ||
| Fatty acids as acute regulators of the proton conductance of hamster brown-fat mitochondria | Q67255436 | ||
| Uncoupling protein 2, in vivo distribution, induction upon oxidative stress, and evidence for translational regulation | Q73247191 | ||
| A role for uncoupling protein-2 as a regulator of mitochondrial hydrogen peroxide generation | Q73626811 | ||
| H+ transport by uncoupling protein (UCP-1) is dependent on a histidine pair, absent in UCP-2 and UCP-3 | Q74134436 | ||
| Only UCP1 can mediate adaptive nonshivering thermogenesis in the cold | Q74394663 | ||
| The uncoupling protein 2 modulates the cytokine balance in innate immunity | Q80257595 | ||
| Uncoupling protein-2 contributes significantly to high mitochondrial proton leak in INS-1E insulinoma cells and attenuates glucose-stimulated insulin secretion | Q81157112 | ||
| UCP1 is essential for adaptive adrenergic nonshivering thermogenesis | Q83092333 | ||
| Participation of ATP/ADP antiporter in oleate- and oleate hydroperoxide-induced uncoupling suppressed by GDP and carboxyatractylate | Q83964250 | ||
| Superoxide activates uncoupling proteins by generating carbon-centered radicals and initiating lipid peroxidation: studies using a mitochondria-targeted spin trap derived from alpha-phenyl-N-tert-butylnitrone. | Q44583900 | ||
| Upregulation of uncoupling protein-3 in skeletal muscle during exercise: a potential antioxidant function | Q28572012 | ||
| Dynamic regulation of uncoupling protein 2 content in INS-1E insulinoma cells | Q28574719 | ||
| UCP2 protects hypothalamic cells from TNF-alpha-induced damage | Q28575626 | ||
| Regulation of the third member of the uncoupling protein family, UCP3, by cold and thyroid hormone | Q28575898 | ||
| Energization-dependent endogenous activation of proton conductance in skeletal muscle mitochondria | Q28579188 | ||
| High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria | Q28610852 | ||
| On the mechanism of fatty acid-induced proton transport by mitochondrial uncoupling protein | Q28646366 | ||
| On the role of uncoupling protein-2 in pancreatic beta cells. | Q30369022 | ||
| Reduced antioxidant capacity and diet-induced atherosclerosis in uncoupling protein-2-deficient mice | Q33359505 | ||
| Molecular evolution of UCP1 and the evolutionary history of mammalian non-shivering thermogenesis | Q33398163 | ||
| Persistent oxidative stress due to absence of uncoupling protein 2 associated with impaired pancreatic beta-cell function | Q33412998 | ||
| Degradation of an intramitochondrial protein by the cytosolic proteasome | Q33636568 | ||
| A significant portion of mitochondrial proton leak in intact thymocytes depends on expression of UCP2. | Q33896736 | ||
| Protective role of uncoupling protein 2 in atherosclerosis | Q33963991 | ||
| Proteolytic and lipolytic responses to starvation | Q33997322 | ||
| Role of uncoupling protein UCP2 in cell-mediated immunity: how macrophage-mediated insulitis is accelerated in a model of autoimmune diabetes. | Q34008199 | ||
| Uncoupling proteins 2 and 3 are highly active H(+) transporters and highly nucleotide sensitive when activated by coenzyme Q (ubiquinone) | Q34080930 | ||
| The on-off switches of the mitochondrial uncoupling proteins | Q34087758 | ||
| Physiological role of UCP3 may be export of fatty acids from mitochondria when fatty acid oxidation predominates: an hypothesis | Q34304137 | ||
| Role of ubiquitin-proteasome degradation pathway in biogenesis efficiency of {beta}-cell ATP-sensitive potassium channels | Q34311574 | ||
| A history of UCP1. | Q34439561 | ||
| Learning new tricks from old dogs: beta-adrenergic receptors teach new lessons on firing up adipose tissue metabolism | Q34649670 | ||
| Reconstitution of novel mitochondrial uncoupling proteins UCP2 and UCP3. | Q34990145 | ||
| A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncoupling. | Q35561876 | ||
| Overexpression of uncoupling protein 3 in skeletal muscle protects against fat-induced insulin resistance | Q35836838 | ||
| Mitochondrial superoxide: production, biological effects, and activation of uncoupling proteins | Q35860305 | ||
| The reactions catalysed by the mitochondrial uncoupling proteins UCP2 and UCP3. | Q36187679 | ||
| Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3. | Q36228620 | ||
| Putative function and physiological relevance of the mitochondrial uncoupling protein-3: involvement in fatty acid metabolism? | Q36356286 | ||
| The physiological regulation of uncoupling proteins | Q36489380 | ||
| Uncoupling proteins: a role in protection against reactive oxygen species--or not? | Q36522086 | ||
| Rapid turnover of mitochondrial uncoupling protein 3 | Q36866583 | ||
| Type 1 diabetic akita mouse hearts are insulin sensitive but manifest structurally abnormal mitochondria that remain coupled despite increased uncoupling protein 3. | Q36943690 | ||
| UCP2 is highly expressed in pancreatic alpha-cells and influences secretion and survival | Q36954492 | ||
| Amino acid metabolism, insulin secretion and diabetes. | Q36979705 | ||
| Novel uncoupling proteins | Q37030116 | ||
| Effect of aging, caloric restriction, and uncoupling protein 3 (UCP3) on mitochondrial proton leak in mice | Q37039107 | ||
| Mitochondrial uncoupling protein 3 and its role in cardiac- and skeletal muscle metabolism | Q37055525 | ||
| Uncoupling proteins: role in insulin resistance and insulin insufficiency | Q37065665 | ||
| Mitochondrial reactive oxygen species are obligatory signals for glucose-induced insulin secretion. | Q37105339 | ||
| UCP2, not a physiologically relevant uncoupler but a glucose sparing switch impacting ROS production and glucose sensing | Q37469361 | ||
| Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes. | Q38299277 | ||
| Inhibition of UCP2 expression reverses diet-induced diabetes mellitus by effects on both insulin secretion and action | Q38305957 | ||
| An intronic single base exchange leads to a brown adipose tissue-specific loss of Ucp3 expression and an altered body mass trajectory | Q38354816 | ||
| Glutamine stimulates translation of uncoupling protein 2mRNA. | Q40130194 | ||
| Thermogenic mechanisms in brown fat | Q40140016 | ||
| UCP2 is a mitochondrial transporter with an unusual very short half-life | Q40180611 | ||
| Translation control of UCP2 synthesis by the upstream open reading frame. | Q40255078 | ||
| Essential role of ubiquitin-proteasome system in normal regulation of insulin secretion | Q40303586 | ||
| Superoxide-mediated activation of uncoupling protein 2 causes pancreatic beta cell dysfunction. | Q40348831 | ||
| Physiological increases in uncoupling protein 3 augment fatty acid oxidation and decrease reactive oxygen species production without uncoupling respiration in muscle cells. | Q40392941 | ||
| Proteasome inhibition alters glucose-stimulated (pro)insulin secretion and turnover in pancreatic {beta}-cells. | Q40459805 | ||
| Pharmacology: uncoupling the agony from ecstasy | Q40544943 | ||
| The basal proton conductance of mitochondria depends on adenine nucleotide translocase content | Q40678073 | ||
| Control of proteolysis by norepinephrine and insulin in brown adipocytes: role of ATP, phosphatidylinositol 3-kinase, and p70 S6K. | Q40718433 | ||
| Uncoupling protein-3 expression in rodent skeletal muscle is modulated by food intake but not by changes in environmental temperature | Q41067789 | ||
| The reconstituted isolated uncoupling protein is a membrane potential driven H+ translocator | Q41429357 | ||
| The physiological significance of mitochondrial proton leak in animal cells and tissues | Q41488872 | ||
| Generating, partitioning, targeting and functioning of superoxide in mitochondria | Q41616360 | ||
| Superoxide production by NADH:ubiquinone oxidoreductase (complex I) depends on the pH gradient across the mitochondrial inner membrane | Q41971010 | ||
| Oxidative damage and phospholipid fatty acyl composition in skeletal muscle mitochondria from mice underexpressing or overexpressing uncoupling protein 3. | Q42049989 | ||
| Cellular metabolism as a basis for immune privilege | Q42091959 | ||
| Peroxisome proliferator-activated receptor gamma coactivator-1-dependent uncoupling protein-2 expression in pancreatic islets of rats: a novel pathway for neural control of insulin secretion. | Q42451812 | ||
| Superoxide activates a GDP-sensitive proton conductance in skeletal muscle mitochondria from king penguin (Aptenodytes patagonicus). | Q42453663 | ||
| Uncoupling protein-1 (UCP1) contributes to the basal proton conductance of brown adipose tissue mitochondria. | Q42458989 | ||
| UCP2 and UCP3 rise in starved rat skeletal muscle but mitochondrial proton conductance is unchanged | Q42481822 | ||
| Physiological levels of mammalian uncoupling protein 2 do not uncouple yeast mitochondria | Q42502013 | ||
| Increased uncoupling protein-2 levels in beta-cells are associated with impaired glucose-stimulated insulin secretion: mechanism of action | Q42504879 | ||
| No evidence for a basal, retinoic, or superoxide-induced uncoupling activity of the uncoupling protein 2 present in spleen or lung mitochondria. | Q42521387 | ||
| Differentiation-dependent expression of cathepsin D and importance of lysosomal proteolysis in the degradation of UCP1 in brown adipocytes | Q42523699 | ||
| Induction and degradation of the uncoupling protein thermogenin in brown adipocytes in vitro and in vivo. Evidence for a rapidly degradable pool. | Q42797470 | ||
| Thyroid hormones directly activate the expression of the human and mouse uncoupling protein-3 genes through a thyroid response element in the proximal promoter region | Q42815157 | ||
| A 211-bp enhancer of the rat uncoupling protein-1 (UCP-1) gene controls specific and regulated expression in brown adipose tissue. | Q42991086 | ||
| Stronger control of ATP/ADP by proton leak in pancreatic beta-cells than skeletal muscle mitochondria | Q43226730 | ||
| Essential role for uncoupling protein-3 in mitochondrial adaptation to fasting but not in fatty acid oxidation or fatty acid anion export | Q43422668 | ||
| Brown-Adipose-Tissue Mitochondria: Photoaffinity Labelling of the Regulatory Site of Energy Dissipation | Q43465451 | ||
| Role of ATP production and uncoupling protein-2 in the insulin secretory defect induced by chronic exposure to high glucose or free fatty acids and effects of peroxisome proliferator-activated receptor-gamma inhibition | Q44114881 | ||
| Mitochondrial uncoupling protein 1 expression in thymocytes. | Q44171334 | ||
| Characterization of a novel metabolic strategy used by drug-resistant tumor cells | Q44175820 | ||
| Skeletal muscle mitochondrial oxidative capacity and uncoupling protein 3 are differently influenced by semistarvation and refeeding | Q44462814 | ||
| P433 | issue | 6-7 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 785-791 | |
| P577 | publication date | 2010-03-06 | |
| P1433 | published in | Biochimica et Biophysica Acta | Q864239 |
| P1476 | title | The regulation and turnover of mitochondrial uncoupling proteins | |
| P478 | volume | 1797 |
| Q34313810 | A deubiquitylating complex required for neosynthesis of a yeast mitochondrial ATP synthase subunit |
| Q37974566 | A new, powerful player in lipoprotein metabolism: brown adipose tissue |
| Q36665069 | Accumulation of newly synthesized F1 in vivo in arabidopsis mitochondria provides evidence for modular assembly of the plant F1Fo ATP synthase |
| Q42498527 | Accumulation of the SET protein in HEK293T cells and mild oxidative stress: cell survival or death signaling |
| Q36307589 | Adipocyte arrestin domain-containing 3 protein (Arrdc3) regulates uncoupling protein 1 (Ucp1) expression in white adipose independently of canonical changes in β-adrenergic receptor signaling |
| Q89975359 | Alterations in Glucose Metabolism During the Transition to Heart Failure: The Contribution of UCP-2 |
| Q89886040 | Amhr2-Cre-Mediated Global Tspo Knockout |
| Q37837646 | Arabidopsis thaliana uncoupling proteins (AtUCPs): insights into gene expression during development and stress response and epigenetic regulation |
| Q50789263 | BAIBA Does Not Regulate UCP-3 Expression in Human Skeletal Muscle as a Response to Aerobic Exercise. |
| Q53505415 | Bone marrow mononuclear cell transplantation improves mitochondrial bioenergetics in the liver of cholestatic rats. |
| Q34026273 | Cellular model of Warburg effect identifies tumor promoting function of UCP2 in breast cancer and its suppression by genipin |
| Q36407271 | Chronic Hyperinsulinemia Causes Selective Insulin Resistance and Down-regulates Uncoupling Protein 3 (UCP3) through the Activation of Sterol Regulatory Element-binding Protein (SREBP)-1 Transcription Factor in the Mouse Heart |
| Q36980245 | Common UCP2 variants contribute to serum urate concentrations and the risk of hyperuricemia |
| Q38711737 | Complex formation and turnover of mitochondrial transporters and ion channels |
| Q51053991 | Concerted expression of the thermogenic and bioenergetic mitochondrial protein machinery in brown adipose tissue. |
| Q33936500 | Control mechanisms in mitochondrial oxidative phosphorylation |
| Q39454284 | Cytoprotective Effect of the UCP2-SIRT3 Signaling Pathway by Decreasing Mitochondrial Oxidative Stress on Cerebral Ischemia-Reperfusion Injury |
| Q39117127 | Early induction of uncoupling protein-2 in pulmonary macrophages in hyperoxia-associated lung injury. |
| Q34796809 | Gene Polymorphisms of ADIPOQ +45T>G, UCP2 -866G>A, and FABP2 Ala54Thr on the Risk of Colorectal Cancer: A Matched Case-Control Study |
| Q28475738 | Genipin-induced inhibition of uncoupling protein-2 sensitizes drug-resistant cancer cells to cytotoxic agents |
| Q57181835 | Identification of new high affinity targets for Roquin based on structural conservation |
| Q64057016 | Immunophenotypic expression of UCP1 in hibernoma and other adipose/non adipose soft tissue tumours |
| Q28392588 | In utero exposure to benzo[a]pyrene increases adiposity and causes hepatic steatosis in female mice, and glutathione deficiency is protective |
| Q35061232 | Increased susceptibility to ethylmercury-induced mitochondrial dysfunction in a subset of autism lymphoblastoid cell lines |
| Q90627351 | Inorganic nitrate and nitrite supplementation fails to improve skeletal muscle mitochondrial efficiency in mice and humans |
| Q36117453 | Insulin resistance improves metabolic and contractile efficiency in stressed rat heart |
| Q35781970 | Isoproterenol Increases Uncoupling, Glycolysis, and Markers of Beiging in Mature 3T3-L1 Adipocytes |
| Q92025953 | Liensinine Inhibits Beige Adipocytes Recovering to white Adipocytes through Blocking Mitophagy Flux In Vitro and In Vivo |
| Q42581553 | Long-term treatment with the pan-PPAR agonist tetradecylthioacetic acid or fish oil is associated with increased cardiac content of n-3 fatty acids in rat. |
| Q39507686 | MSL1 is a mechanosensitive ion channel that dissipates mitochondrial membrane potential and maintains redox homeostasis in mitochondria during abiotic stress. |
| Q37357426 | Mesenchymal stem cell transplantation for the infarcted heart: therapeutic potential for insulin resistance beyond the heart |
| Q37120693 | Mitochondria Biogenesis and Bioenergetics Gene Profiles in Isogenic Prostate Cells with Different Malignant Phenotypes |
| Q35791952 | Mitochondrial Gene Expression Profiles Are Associated with Maternal Psychosocial Stress in Pregnancy and Infant Temperament |
| Q39173130 | Mitochondrial and redox abnormalities in autism lymphoblastoid cells: a sibling control study |
| Q38246367 | Mitochondrial oxidative metabolism and uncoupling proteins in the failing heart |
| Q35132584 | Mitochondrial reprogramming induced by CaMKIIδ mediates hypertrophy decompensation |
| Q37453274 | Oxidative stress induces mitochondrial dysfunction in a subset of autism lymphoblastoid cell lines in a well-matched case control cohort |
| Q33575000 | Oxidative stress induces mitochondrial dysfunction in a subset of autistic lymphoblastoid cell lines |
| Q64275087 | Protection against pressure overload-induced right heart failure by uncoupling protein 2 silencing |
| Q28383361 | Redox regulation of mitochondrial function |
| Q36100307 | Reversal of diet-induced obesity and insulin resistance by inducible genetic ablation of GRK2. |
| Q38326204 | Skeletal muscle respiratory capacity is enhanced in rats consuming an obesogenic Western diet. |
| Q46963418 | Stat3 mediates LIF-induced protection of astrocytes against toxic ROS by upregulating the UPC2 mRNA pool |
| Q50063222 | Systems genetic analysis of brown adipose tissue function |
| Q37722849 | Tempol protects cardiomyocytes from nucleoside reverse transcriptase inhibitor-induced mitochondrial toxicity |
| Q39344606 | The ERalpha/ERbeta ratio determines oxidative stress in breast cancer cell lines in response to 17beta-estradiol. |
| Q37174249 | The mitochondrial component of intracrine action |
| Q37903726 | The role of uncoupling protein 2 (UCP2) on the development of type 2 diabetes mellitus and its chronic complications |
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| Q55086939 | Time-of-Day Effects on Metabolic and Clock-Related Adjustments to Cold. |
| Q42803482 | Triiodothyronine regulates distribution of thyroid hormone receptors by activating AMP-activated protein kinase in 3T3-L1 adipocytes and induces uncoupling protein-1 expression |
| Q38117540 | UCP2, a mitochondrial protein regulated at multiple levels. |
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| Q28480923 | Upregulation of UCP2 by adiponectin: the involvement of mitochondrial superoxide and hnRNP K |
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