The role of uncoupling protein 2 (UCP2) on the development of type 2 diabetes mellitus and its chronic complications (scientific article published on June 2011)

Multicenter study of the prevalence of diabetes mellitus and impaired glucose tolerance in the urban Brazilian population aged 30-69 yr. The Brazilian Cooperative Group on the Study of Diabetes Prevalence

Q39233637

An uncoupling protein 2 gene variant is associated with a raised body mass index but not Type II diabetes.

Q39511136

Superoxide-mediated activation of uncoupling protein 2 causes pancreatic beta cell dysfunction.

Q40348831

Associations of the UCP2 gene locus with asymptomatic carotid atherosclerosis in middle-aged women.

Q40479819

Uncoupling protein 2 promoter polymorphism -866G/A affects its expression in beta-cells and modulates clinical profiles of Japanese type 2 diabetic patients

Q40595110

Mutational analysis of the UCP2 core promoter and relationships of variants with obesity

Q40615223

A functional polymorphism in the promoter of UCP2 enhances obesity risk but reduces type 2 diabetes risk in obese middle-aged humans.

Q40694134

Reactive oxygen species, mitochondria, apoptosis and aging.

Q41601406

Dietary fatty acids Up-regulate the expression of UCP2 in 3T3-L1 preadipocytes

Q42834382

Overexpression of uncoupling protein 2 inhibits glucose-stimulated insulin secretion from rat islets.

Q43616980

Lack of association between the uncoupling protein-2 Ala55Val gene polymorphism and phenotypic features of the Metabolic Syndrome

Q44183775

A common polymorphism in the promoter of UCP2 contributes to the variation in insulin secretion in glucose-tolerant subjects

Q44418749

Uncoupling protein-2 polymorphisms in type 2 diabetes, obesity, and insulin secretion

Q44547298

The -866A/A genotype in the promoter of the human uncoupling protein 2 gene is associated with insulin resistance and increased risk of type 2 diabetes.

Q44953952

The common -866G/A polymorphism in the promoter region of the UCP-2 gene is associated with reduced risk of type 2 diabetes in Caucasians from Italy

Q45161407

The uncoupling protein 2 Ala55Val polymorphism is associated with diabetes mellitus: the CARDIA study

Q46541998

The common -866G>A variant in the promoter of UCP2 is associated with decreased risk of coronary artery disease in type 2 diabetic men.

Q46810127

Putative role of polymorphisms in UCP1-3 genes for diabetic nephropathy

Q47666215

Association between uncoupling protein polymorphisms (UCP2-UCP3) and energy metabolism/obesity in Pima indians.

Q47700926

The mitochondrial uncoupling-protein homologues

Q50308475

Polymorphisms of the UCP2 gene are associated with proliferative diabetic retinopathy in patients with diabetes mellitus

Q51801627

Uncoupling Protein-2 Participates in Cellular Defense against Oxidative Stress in Clonal β-Cells

Q57672115

Association between obesity and insulin resistance with UCP2–UCP3 gene variants in Spanish children and adolescents

Q58074954

Diagnosis and Classification of Diabetes Mellitus

Q22255454

Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia

Q24324798

Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1

Q24679555

Decreased insulin-stimulated ATP synthesis and phosphate transport in muscle of insulin-resistant offspring of type 2 diabetic parents

Q24812499

Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production

Q28139177

Retinopathy in diabetes

Q28166601

A common polymorphism in the promoter of UCP2 is associated with decreased risk of obesity in middle-aged humans

Q28191413

Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes

Q29616567

Mitochondrial dysfunction and type 2 diabetes

Q29617913

On the role of uncoupling protein-2 in pancreatic beta cells.

Q30369022

The uncoupling protein 1 gene, UCP1, is expressed in mammalian islet cells and associated with acute insulin response to glucose in African American families from the IRAS Family Study

Q30445084

Uncoupling proteins--a new family of proteins with unknown function

Q30684562

Expression modification of uncoupling proteins and MnSOD in retinal endothelial cells and pericytes induced by high glucose: the role of reactive oxygen species in diabetic retinopathy

Q33245617

The regulation and turnover of mitochondrial uncoupling proteins.

Q33936374

The on-off switches of the mitochondrial uncoupling proteins

Q34087758

Uncoupling proteins: functional characteristics and role in the pathogenesis of obesity and Type II diabetes

Q34325426

Mitochondrial uncoupling protein gene cluster variation (UCP2–UCP3) and the risk of incident type 2 diabetes mellitus: The Women's Genome Health Study

Q34479305

Genetic variants in the UCP2-UCP3 gene cluster and risk of diabetes in the Women's Health Initiative Observational Study.

Q34742294

Uncoupling proteins, dietary fat and the metabolic syndrome

Q35070365

Uncoupling protein 2 and islet function

Q35641732

Links between fatty acids and expression of UCP2 and UCP3 mRNAs

Q35805093

Mitochondrial superoxide: production, biological effects, and activation of uncoupling proteins

Q35860305

The reactions catalysed by the mitochondrial uncoupling proteins UCP2 and UCP3.