scholarly article | Q13442814 |
P50 | author | Romain Harmancey | Q86663961 |
P2093 | author name string | Heinrich Taegtmeyer | |
Derek L Haight | |||
Kayla A Watts | |||
P2860 | cites work | Uncoupling protein-3: a new member of the mitochondrial carrier family with tissue-specific expression | Q24309291 |
UCP3: an uncoupling protein homologue expressed preferentially and abundantly in skeletal muscle and brown adipose tissue | Q24312228 | ||
SREBP-1c and Sp1 interact to regulate transcription of the gene for phosphoenolpyruvate carboxykinase (GTP) in the liver | Q28240899 | ||
Increased mitochondrial uncoupling proteins, respiratory uncoupling and decreased efficiency in the chronically infarcted rat heart | Q28570211 | ||
Identification of conserved cis-elements and transcription factors required for sterol-regulated transcription of stearoyl-CoA desaturase 1 and 2 | Q28646392 | ||
Insulin-resistant heart exhibits a mitochondrial biogenic response driven by the peroxisome proliferator-activated receptor-alpha/PGC-1alpha gene regulatory pathway. | Q30359509 | ||
A new role for sterol regulatory element binding protein 1 transcription factors in the regulation of muscle mass and muscle cell differentiation | Q33648820 | ||
Decreased long-chain fatty acid oxidation impairs postischemic recovery of the insulin-resistant rat heart | Q33713702 | ||
Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats | Q33857313 | ||
The regulation and turnover of mitochondrial uncoupling proteins. | Q33936374 | ||
Genetic deletion in uncoupling protein 3 augments 18F-fluorodeoxyglucose cardiac uptake in the ischemic heart | Q34021788 | ||
SREBP-1 interacts with hepatocyte nuclear factor-4 alpha and interferes with PGC-1 recruitment to suppress hepatic gluconeogenic genes. | Q34289658 | ||
Western diet changes cardiac acyl-CoA composition in obese rats: a potential role for hepatic lipogenesis | Q34559873 | ||
Adaptation and maladaptation of the heart in diabetes: Part I: general concepts | Q34592521 | ||
Gene expression profiling in human skeletal muscle during recovery from eccentric exercise | Q34758964 | ||
A novel SP1/SP3 dependent intronic enhancer governing transcription of the UCP3 gene in brown adipocytes | Q35082470 | ||
Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: Part I. | Q35540861 | ||
Metabolic stress-induced activation of FoxO1 triggers diabetic cardiomyopathy in mice | Q35780290 | ||
Carbohydrate responsive element binding protein (ChREBP) and sterol regulatory element binding protein-1c (SREBP-1c): two key regulators of glucose metabolism and lipid synthesis in liver | Q36055803 | ||
UCP3 regulates cardiac efficiency and mitochondrial coupling in high fat-fed mice but not in leptin-deficient mice. | Q36410680 | ||
Hyperinsulinemia as an independent risk factor for ischemic heart disease. | Q51581884 | ||
Differential expression of cardiac uncoupling proteins 2 and 3 in response to myocardial ischemia-reperfusion in rats. | Q54227505 | ||
Angiographic Findings and Outcome in Diabetic Patients Treated With Thrombolytic Therapy for Acute Myocardial Infarction: The GUSTO-I Experience | Q56945225 | ||
Myocardial steatosis, cardiac remodelling and fitness in insulin-sensitive and insulin-resistant obese women | Q56981574 | ||
Functional Relationship between MyoD and Peroxisome Proliferator-Activated Receptor-Dependent Regulatory Pathways in the Control of the Human Uncoupling Protein-3 Gene Transcription | Q60636891 | ||
The plasma free fatty acid rebound induced by nicotinic acid | Q72252881 | ||
Early postoperative outcome and medium-term survival in 540 diabetic and 2239 nondiabetic patients undergoing coronary artery bypass grafting | Q74805086 | ||
Streptozotocin treatment upregulates uncoupling protein 3 expression in the rat heart | Q77766014 | ||
Activation of a novel long-chain free fatty acid generation and export system in mitochondria of diabetic rat hearts | Q79949239 | ||
Cardiac steatosis in diabetes mellitus: a 1H-magnetic resonance spectroscopy study | Q80795946 | ||
Mitochondrial uncoupling: a key contributor to reduced cardiac efficiency in diabetes. | Q36547048 | ||
ADD1: a novel helix-loop-helix transcription factor associated with adipocyte determination and differentiation | Q36694542 | ||
Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes | Q36698641 | ||
Bioinformatic profiling of the transcriptional response of adult rat cardiomyocytes to distinct fatty acids | Q36727375 | ||
Role of uncoupling protein 3 in ischemia-reperfusion injury, arrhythmias, and preconditioning | Q36837997 | ||
Myocardial AKT: the omnipresent nexus | Q36908289 | ||
Type 1 diabetic akita mouse hearts are insulin sensitive but manifest structurally abnormal mitochondria that remain coupled despite increased uncoupling protein 3. | Q36943690 | ||
Genetic deletion of uncoupling protein 3 exaggerates apoptotic cell death in the ischemic heart leading to heart failure. | Q36974257 | ||
Molecular mechanisms for myocardial mitochondrial dysfunction in the metabolic syndrome | Q37053844 | ||
Selective versus total insulin resistance: a pathogenic paradox | Q37076798 | ||
Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle | Q37175187 | ||
Susceptibility to myocardial ischemia reperfusion injury at early stage of type 1 diabetes in rats | Q37357405 | ||
Myocardial lipid accumulation in patients with pressure-overloaded heart and metabolic syndrome | Q37382176 | ||
Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2. | Q37382401 | ||
Myocardial fatty acid metabolism in health and disease | Q37677921 | ||
Lipid metabolism and toxicity in the heart | Q38017379 | ||
Microarray analyses of SREBP-1a and SREBP-1c target genes identify new regulatory pathways in muscle | Q38289985 | ||
Transcriptional effects of chronic Akt activation in the heart. | Q38290130 | ||
Physiological increases in uncoupling protein 3 augment fatty acid oxidation and decrease reactive oxygen species production without uncoupling respiration in muscle cells. | Q40392941 | ||
Insulin regulation of sterol regulatory element-binding protein-1 expression in L-6 muscle cells and 3T3 L1 adipocytes | Q40547543 | ||
Up-regulation of uncoupling protein 3 gene expression by fatty acids and agonists for PPARs in L6 myotubes. | Q40779525 | ||
A novel intronic peroxisome proliferator-activated receptor gamma enhancer in the uncoupling protein (UCP) 3 gene as a regulator of both UCP2 and -3 expression in adipocytes | Q40812851 | ||
Uncoupling protein 3 (UCP3) stimulates glucose uptake in muscle cells through a phosphoinositide 3-kinase-dependent mechanism. | Q40816499 | ||
Uncoupling protein 3 mediates H₂O₂ preconditioning-afforded cardioprotection through the inhibition of MPTP opening | Q41682803 | ||
A high fat diet increases mitochondrial fatty acid oxidation and uncoupling to decrease efficiency in rat heart | Q41814555 | ||
Lack of UCP3 does not affect skeletal muscle mitochondrial function under lipid-challenged conditions, but leads to sudden cardiac death | Q41845774 | ||
Effects of insulin replacements, inhibitors of angiotensin, and PKCbeta's actions to normalize cardiac gene expression and fuel metabolism in diabetic rats | Q42509701 | ||
Regulation of sterol regulatory-element binding protein 1 gene expression in liver: role of insulin and protein kinase B/cAkt | Q42996869 | ||
Involvement of GSK-3β in attenuation of the cardioprotective effect of ischemic preconditioning in diabetic rat heart. | Q43050253 | ||
Effect of experimental hyperinsulinemia on insulin binding and glucose transport in isolated rat adipocytes | Q43431397 | ||
Uncoupling protein 3 transcription is regulated by peroxisome proliferator-activated receptor (alpha) in the adult rodent heart | Q43548122 | ||
Uncoupling protein 3 content is decreased in skeletal muscle of patients with type 2 diabetes. | Q43808977 | ||
Human obesity and type 2 diabetes are associated with alterations in SREBP1 isoform expression that are reproduced ex vivo by tumor necrosis factor-alpha | Q43935429 | ||
Diabetes mellitus, myocardial reperfusion, and outcome in patients with acute ST-elevation myocardial infarction treated with primary angioplasty (from HORIZONS AMI). | Q43986424 | ||
Sterol regulatory element binding protein-1c expression and action in rat muscles: insulin-like effects on the control of glycolytic and lipogenic enzymes and UCP3 gene expression | Q44007196 | ||
Diabetes mellitus increases short-term mortality and morbidity in patients undergoing coronary artery bypass graft surgery | Q44079557 | ||
Relationship between obesity, insulin resistance, and coronary heart disease risk | Q44133524 | ||
Cholesteryl ester transfer protein expression is down-regulated in hyperinsulinemic transgenic mice | Q44516295 | ||
Coronary artery bypass grafting in type II diabetic patients: a comparison between insulin-dependent and non-insulin-dependent patients at short- and mid-term follow-up | Q44927558 | ||
Diurnal variations in the responsiveness of cardiac and skeletal muscle to fatty acids | Q45005728 | ||
Plasma free fatty acids and peroxisome proliferator-activated receptor alpha in the control of myocardial uncoupling protein levels | Q46818642 | ||
Transcription of the human uncoupling protein 3 gene is governed by a complex interplay between the promoter and intronic sequences | Q47727759 | ||
The mitochondrial uncoupling-protein homologues | Q50308475 | ||
Intramyocardial lipid accumulation in the failing human heart resembles the lipotoxic rat heart. | Q50782443 | ||
Acute starvation in C57BL/6J mice increases myocardial UCP2 and UCP3 protein expression levels and decreases mitochondrial bio-energetic function. | Q51389528 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 52 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | insulin resistance | Q1053470 |
P304 | page(s) | 30947-30961 | |
P577 | publication date | 2015-11-10 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Chronic Hyperinsulinemia Causes Selective Insulin Resistance and Down-regulates Uncoupling Protein 3 (UCP3) through the Activation of Sterol Regulatory Element-binding Protein (SREBP)-1 Transcription Factor in the Mouse Heart | |
P478 | volume | 290 |
Q54978476 | Deficiency of PRKD2 triggers hyperinsulinemia and metabolic disorders. |
Q48166254 | Glucose regulates the intrinsic inflammatory response of the heart to surgically induced hypothermic ischemic arrest and reperfusion |
Q64264371 | Important Trends in UCP3 Investigation |
Q39159635 | Insulin and β Adrenergic Receptor Signaling: Crosstalk in Heart |
Q47722955 | Mitochondrial uncoupling proteins: subtle regulators of cellular redox signaling |
Q89944024 | Modulation of Fatty Acid-Related Genes in the Response of H9c2 Cardiac Cells to Palmitate and n-3 Polyunsaturated Fatty Acids |
Q50057684 | Temporal partitioning of adaptive responses of the murine heart to fasting |
Q58100959 | Uncoupling protein 3 deficiency impairs myocardial fatty acid oxidation and contractile recovery following ischemia/reperfusion |
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