The Scientific Foundation for personal genomics: recommendations from a National Institutes of Health-Centers for Disease Control and Prevention multidisciplinary workshop

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The Scientific Foundation for personal genomics: recommendations from a National Institutes of Health-Centers for Disease Control and Prevention multidisciplinary workshop is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1046227163
P356DOI10.1097/GIM.0B013E3181B13A6C
P932PMC publication ID2936269
P698PubMed publication ID19617843

P50authorFrancis CollinsQ336658
Centers for Disease Control and PreventionQ583725
George M. ChurchQ3298995
John IoannidisQ6251482
Kári StefánssonQ6453246
Robert C. GreenQ7342606
Sharon F. TerryQ7490049
Sharon L R KardiaQ88218091
Philip GreenlandQ93019727
Ralph J. CoatesQ124654554
Paul L. KimmelQ130390505
Kenneth OffitQ20732365
Michael S. LauerQ27205541
Stephen ChanockQ27662321
Jay M. BernhardtQ43836495
Cecile JanssensQ58477081
Barry R. DavisQ64684716
Muin J. KhouryQ64746271
Marta GwinnQ64748945
Sheri D SchullyQ64749037
Jeffrey GulcherQ66823431
Jianfeng XuQ67190177
Rebekah RasoolyQ38155014
P2093author name stringMark H Greene
Mitchell H Gail
John S Witte
Geoffrey S Ginsburg
Michele Cargill
W Gregory Feero
Gregory J Downing
Steven M Teutsch
J Scott Roberts
David F Ransohoff
Colleen M McBride
Susan Friedman
Angela Trepanier
Robert T Croyle
Kathy L Hudson
Denise G Simons-Morton
Amy Duross
Amy M Miller
Andro Hsu
Kay L Wanke
P2860cites workPoint: genetic risk feedback for common disease time to test the watersQ81251130
Counterpoint: genetic risk feedback for common disease time to test the watersQ81251134
Cohort studies and the genetics of complex diseaseQ83106332
Personalized genetic prediction: too limited, too expensive, or too soon?Q83203055
Update on the methods of the U.S. Preventive Services Task Force: insufficient evidenceQ83288867
When is measuring sensitivity and specificity sufficient to evaluate a diagnostic test, and when do we need randomized trials?Q83930135
Interpretation of genetic association studies: markers with replicated highly significant odds ratios may be poor classifiersQ21563322
Meta-analysis in genome-wide association studiesQ24273398
Genome-wide association studies for complex traits: consensus, uncertainty and challengesQ24550632
Rare independent mutations in renal salt handling genes contribute to blood pressure variationQ24627187
Blazing a trail: a public health research agenda in genomics and chronic diseaseQ25257780
Letting the genome out of the bottle--will we get our wish?Q28264215
Size matters: just how big is BIG?: Quantifying realistic sample size requirements for human genome epidemiologyQ28755468
General cardiovascular risk profile for use in primary care: the Framingham Heart StudyQ29614189
Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyondQ29614697
A HapMap harvest of insights into the genetics of common diseaseQ29614875
Genetic mapping in human diseaseQ29614943
Pharmacogenomics: candidate gene identification, functional validation and mechanismsQ33375573
Estimation of the warfarin dose with clinical and pharmacogenetic dataQ33410725
A health services research agenda for cellular, molecular and genomic technologies in cancer careQ33749983
Integrating the predictiveness of a marker with its performance as a classifierQ34129175
Multiple rare variants in NPC1L1 associated with reduced sterol absorption and plasma low-density lipoprotein levelsQ34478587
Risky communication: pitfalls in counseling about risk, and how to avoid themQ80251479
The case for a global human genome epidemiology initiativeQ80800985
The genome gets personal--almostQ80893890
Genomic profiles for disease risk: predictive or premature?Q80893894
A meta-analysis of the effect of mediated health communication campaigns on behavior change in the United StatesQ40532001
An unwelcome side effect of direct-to-consumer personal genome testing: raiding the medical commonsQ42091906
Gauging the performance of SNPs, biomarkers, and clinical factors for predicting risk of breast cancerQ42791172
Pharmacogenetics--tailoring treatment for the outliersQ46116659
Cost-effectiveness of using pharmacogenetic information in warfarin dosing for patients with nonvalvular atrial fibrillationQ46157298
Pharmacogenomics--ready for prime time?Q46716977
The feasibility of online genetic testing for lung cancer susceptibility: uptake of a web-based protocol and decision outcomesQ46747840
Predictors of attrition and weight loss in an adolescent weight control programQ47241118
Developing a center for comparative effectiveness informationQ47586561
Evaluating the utility of personal genomic informationQ47593006
Genetic susceptibility testing versus family history-based risk assessment: Impact on perceived risk of Alzheimer diseaseQ49141542
The evidence dilemma in genomic medicineQ50769689
Incorporating biomarkers of exposure and genetic susceptibility into smoking cessation treatment: effects on smoking-related cognitions, emotions, and behavior changeQ51108076
A navigator for human genome epidemiologyQ51895975
Effects of attributing serious mental illnesses to genetic causes on orientations to treatmentQ51920543
What is the clinical utility of genetic testing?Q52012351
Time to check CHEK2 in families with breast cancer?Q55047407
Misdirected precautionQ57261722
Turning the Pump Handle: Evolving Methods for Integrating the Evidence on Gene-Disease AssociationQ57542900
Beyond odds ratios — communicating disease risk based on genetic profilesQ58047301
Psychological impact of genetic testing for familial hypercholesterolemia within a previously aware population: A randomized controlled trialQ60697564
Difficulty in losing weight by behavioral intervention for women with Trp64Arg polymorphism of the beta3-adrenergic receptor geneQ73807082
Genome-based prediction of common diseases: advances and prospectsQ34851798
Assessing the value of risk predictions by using risk stratification tablesQ34969023
Population screening in the age of genomic medicineQ35037759
Genetic testing for Alzheimer's disease and its impact on insurance purchasing behaviorQ35567406
Simple tools for understanding risks: from innumeracy to insightQ36037510
On criteria for evaluating models of absolute riskQ36072628
Pharmacogenetics and pharmacogenomics: development, science, and translationQ36583761
A critical appraisal of the scientific basis of commercial genomic profiles used to assess health risks and personalize health interventionsQ36719129
Health behavior changes after genetic risk assessment for Alzheimer disease: The REVEAL StudyQ36790111
Discriminatory accuracy from single-nucleotide polymorphisms in models to predict breast cancer riskQ36858843
Putting science over supposition in the arena of personalized genomicsQ36865829
Assessing the combined impact of 18 common genetic variants of modest effect sizes on type 2 diabetes riskQ36943793
Assessment of cumulative evidence on genetic associations: interim guidelinesQ36952959
The continuum of translation research in genomic medicine: how can we accelerate the appropriate integration of human genome discoveries into health care and disease prevention?Q37029751
Rare loss-of-function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans.Q37036119
Recommendations from the EGAPP Working Group: testing for cytochrome P450 polymorphisms in adults with nonpsychotic depression treated with selective serotonin reuptake inhibitorsQ37037058
Cardiovascular disease risk prediction with and without knowledge of genetic variation at chromosome 9p21.3.Q37069329
Psychosocial issues in genetic testing for familial adenomatous polyposis: a review of the literature.Q37211096
The Evaluation of Genomic Applications in Practice and Prevention (EGAPP) Initiative: methods of the EGAPP Working GroupQ37277889
Looking to the future of new media in health marketing: deriving propositions based on traditional theories.Q37303272
Pharmacogenomic dosing of warfarin: ready or not?Q37334317
Recommendations from the EGAPP Working Group: can UGT1A1 genotyping reduce morbidity and mortality in patients with metastatic colorectal cancer treated with irinotecan?Q37345971
Recommendations from the EGAPP Working Group: genetic testing strategies in newly diagnosed individuals with colorectal cancer aimed at reducing morbidity and mortality from Lynch syndrome in relativesQ37345978
Recommendations from the EGAPP Working Group: can tumor gene expression profiling improve outcomes in patients with breast cancer?Q37345983
The genomic applications in practice and prevention networkQ37345987
Impact of adding a single allele in the 9p21 locus to traditional risk factors on reclassification of coronary heart disease risk and implications for lipid-modifying therapy in the Atherosclerosis Risk in Communities studyQ37408982
Psychosocial aspects of DNA testing for hereditary hemochromatosis in at-risk individuals: a systematic reviewQ37421773
Disclosure of APOE genotype for risk of Alzheimer's diseaseQ37423417
Predicting type 2 diabetes based on polymorphisms from genome-wide association studies: a population-based studyQ40060574
Chromosome 9p21.3 coronary heart disease locus genotype and prospective risk of CHD in healthy middle-aged men.Q40126925
The impact of genotype frequencies on the clinical validity of genomic profiling for predicting common chronic diseasesQ40182769
Using wireless handheld computers and tailored text messaging to reduce negative consequences of drinking alcohol.Q40203757
Use and misuse of the receiver operating characteristic curve in risk predictionQ40241086
Self-regulation and the behavioural response to DNA risk information: a theoretical analysis and framework for future researchQ40389106
Who seeks genetic susceptibility testing for Alzheimer's disease? Findings from a multisite, randomized clinical trialQ40494480
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectpersonal genomicsQ7170583
workshopQ27556165
P1104number of pages9
P304page(s)559-567
P577publication date2009-08-01
P1433published inGenetics in MedicineQ15765508
P1476titleThe Scientific Foundation for personal genomics: recommendations from a National Institutes of Health-Centers for Disease Control and Prevention multidisciplinary workshop
P478volume11

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