review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1152/PHYSREV.2001.81.1.299 |
P698 | PubMed publication ID | 11152760 |
P50 | author | Olivier J Manzoni | Q37381421 |
P2093 | author name string | M J Christie | |
J T Williams | |||
P2860 | cites work | Enkephalin regulates the levels of cyclic nucleotides in neuroblastoma x glioma hybrid cells. | Q55492124 |
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | opioid | Q427523 |
P304 | page(s) | 299-343 | |
P577 | publication date | 2001-01-01 | |
P1433 | published in | Physiological Reviews | Q1091827 |
P1476 | title | Cellular and synaptic adaptations mediating opioid dependence | |
P478 | volume | 81 |
Q24670315 | 75 years of opioid research: the exciting but vain quest for the Holy Grail |
Q34459746 | A RAVE about opioid withdrawal |
Q44483117 | A double-lumen intrathecal catheter for studies of modulation of spinal opiate tolerance |
Q35123224 | A mu-delta opioid receptor brain atlas reveals neuronal co-occurrence in subcortical networks |
Q44351247 | A novel opioid receptor-mediated enhancement of GABAA receptor function induced by stress in ventral tegmental area neurons |
Q45007590 | A single in vivo exposure to cocaine abolishes endocannabinoid-mediated long-term depression in the nucleus accumbens. |
Q90702264 | A tetrapeptide class of biased analgesics from an Australian fungus targets the µ-opioid receptor |
Q36745935 | A thalamic input to the nucleus accumbens mediates opiate dependence |
Q37352453 | Absence and rescue of morphine withdrawal in GIRK/Kir3 knock-out mice. |
Q92967463 | Acute Tramadol-Induced Cellular Tolerance and Dependence of Ventral Tegmental Area Dopaminergic Neurons: An In Vivo Electrophysiological Study |
Q36032904 | Acute opioid dependence: characterizing the early adaptations underlying drug withdrawal |
Q22337278 | Addiction and the brain: The neurobiology of compulsion and its persistence |
Q36741908 | Addiction: the clinical interface |
Q35023218 | Adeno-associated viral transfer of opioid receptor gene to primary sensory neurons: a strategy to increase opioid antinociception |
Q47137668 | Agmatine Prevents Adaptation of the Hippocampal Glutamate System in Chronic Morphine-Treated Rats |
Q42857247 | Agmatine modulates neuroadaptations of glutamate transmission in the nucleus accumbens of repeated morphine-treated rats |
Q42957874 | Agonist-dependent postsynaptic effects of opioids on miniature excitatory postsynaptic currents in cultured hippocampal neurons |
Q34722029 | Agonist-selective mechanisms of GPCR desensitization |
Q36807249 | Agonist-specific regulation of mu-opioid receptor desensitization and recovery from desensitization |
Q34726976 | Alteration of the mu opioid receptor: Ca2+ channel signaling pathway in a subset of rat sensory neurons following chronic femoral artery occlusion |
Q44396263 | Altered expression and uptake activity of spinal glutamate transporters after nerve injury contribute to the pathogenesis of neuropathic pain in rats. |
Q44085207 | Altered nucleus accumbens circuitry mediates pain-induced antinociception in morphine-tolerant rats. |
Q44330720 | Ammonium pyrrolidine dithiocarbamate and RS 102895 attenuate opioid withdrawal in vivo and in vitro |
Q60044735 | An electrically-controlled programmable microfluidic concentration waveform generator |
Q55646588 | An emerging new paradigm in opioid withdrawal: a critical role for glia-neuron signaling in the periaqueductal gray. |
Q34957285 | Analgesic tone conferred by constitutively active mu opioid receptors in mice lacking β-arrestin 2 |
Q35589969 | Analysis of opioid efficacy, tolerance, addiction and dependence from cell culture to human |
Q34065808 | Anatomically dissociable effects of dopamine D1 receptor agonists on reward and relief of withdrawal in morphine-dependent rats |
Q36973602 | Androgens and opiates: testosterone interaction with morphine self-administration in male rats |
Q90633295 | Anxiety, Depression, and Insomnia Among Adults With Opioid Dependence Treated With Extended-Release Naltrexone vs Buprenorphine-Naloxone: A Randomized Clinical Trial and Follow-up Study |
Q90291018 | Assessing the Effects of Opioids on Pathological Memory by a Computational Model |
Q94052431 | Astrocytic hypertrophy in the rat ventral tegmental area following chronic morphine differs with age |
Q33817905 | Autoantibodies to the delta-opioid receptor function as opioid agonists and display immunomodulatory activity |
Q44334988 | Beta-arrestin2 and c-Src regulate the constitutive activity and recycling of mu opioid receptors in dorsal root ganglion neurons. |
Q37318106 | Bidirectional effects of fentanyl on dendritic spines and AMPA receptors depend upon the internalization of mu opioid receptors |
Q33613252 | Biomarkers of morphine tolerance and dependence are prevented by morphine-induced endocytosis of a mutant mu-opioid receptor |
Q35812604 | Blockade of PDGFR-β activation eliminates morphine analgesic tolerance |
Q42601949 | Brain region specific actions of regulator of G protein signaling 4 oppose morphine reward and dependence but promote analgesia |
Q44580806 | Brain region-specific mechanisms for acute morphine-induced mitogen-activated protein kinase modulation and distinct patterns of activation during analgesic tolerance and locomotor sensitization. |
Q43999190 | Brain-derived neurotrophic factor is essential for opiate-induced plasticity of noradrenergic neurons. |
Q44241786 | Butorphanol dependence and withdrawal decrease hippocampal kappa 2-opioid receptor binding |
Q37252077 | Caged naloxone reveals opioid signaling deactivation kinetics |
Q36741881 | Cellular neuroadaptations to chronic opioids: tolerance, withdrawal and addiction |
Q34727632 | Central neuropeptide systems and respiratory control during development |
Q44975439 | Changes in c-fos expression in the rat heart during morphine withdrawal. Involvement of alpha2-adrenoceptors. |
Q44343244 | Changes in the brain κ-opioid receptor levels of rats in withdrawal from physical dependence upon butorphanol |
Q35764822 | Chronic Opium Treatment Can Differentially Induce Brain and Liver Cells Apoptosis in Diabetic and Non-diabetic Male and Female Rats |
Q43971279 | Chronic morphine treatment alters endogenous opioid control of hippocampal mossy fiber synaptic transmission |
Q39832239 | Chronic morphine use does not induce peripheral tolerance in a rat model of inflammatory pain |
Q37386620 | Communication networks in the brain: neurons, receptors, neurotransmitters, and alcohol |
Q36102932 | Contribution of dopamine receptors to periaqueductal gray-mediated antinociception. |
Q41847530 | Decreased mu-opioid receptor signalling and a reduction in calcium current density in sensory neurons from chronically morphine-treated mice. |
Q44351416 | Delta and mu opioid receptors from the brain of a urodele amphibian, the rough-skinned newt Taricha granulosa: cloning, heterologous expression, and pharmacological characterization |
Q36438816 | Delta opioid receptor analgesia: recent contributions from pharmacology and molecular approaches |
Q33811673 | Delta opioid receptors presynaptically regulate cutaneous mechanosensory neuron input to the spinal cord dorsal horn |
Q42076848 | Delta receptors are required for full inhibitory coupling of mu-receptors to voltage-dependent Ca(2+) channels in dorsal root ganglion neurons |
Q44340810 | Delta-opioid receptor expression in the ventral tegmental area protects against elevated alcohol consumption. |
Q44318924 | Dependence on morphine impairs the induction of long-term potentiation in the CA1 region of rat hippocampal slices |
Q44350051 | Determination of μ-, δ- and κ-opioid receptors in forebrain cortex of rats exposed to morphine for 10 days: Comparison with animals after 20 days of morphine withdrawal |
Q38187199 | Different mechanisms of homologous and heterologous μ-opioid receptor phosphorylation |
Q35076051 | Differential activation and trafficking of micro-opioid receptors in brain slices |
Q38617993 | Differential desensitization observed at multiple effectors of somatic mu opioid receptors underlies sustained agonist-mediated inhibition of proopiomelanocortin neuron activity |
Q43890669 | Differential desensitization of responses mediated by presynaptic and postsynaptic A1 adenosine receptors. |
Q34701724 | Differential expression and sensitivity of presynaptic and postsynaptic opioid receptors regulating hypothalamic proopiomelanocortin neurons |
Q79537690 | Differential involvement of 3', 5'-cyclic adenosine monophosphate-dependent protein kinase in regulation of Fos and tyrosine hydroxylase expression in the heart after naloxone induced morphine withdrawal |
Q44342358 | Differential involvement of the mu and kappa opioid receptors in spatial learning |
Q35730740 | Direct Facilitatory Role of Paragigantocellularis Neurons in Opiate Withdrawal-Induced Hyperactivity of Rat Locus Coeruleus Neurons: An In Vitro Study. |
Q40447776 | Discharge activities of neurons in the nucleus paragigantocellularis during the development of morphine tolerance and dependence: a single unit study in chronically implanted rats. |
Q35911045 | Distinct effects of individual opioids on the morphology of spines depend upon the internalization of mu opioid receptors |
Q36741486 | Distinct roles of adenylyl cyclases 1 and 8 in opiate dependence: behavioral, electrophysiological, and molecular studies |
Q34624598 | Do opioids induce hyperalgesia? |
Q40555581 | Dopamine D3 receptor dysfunction prevents anti-nociceptive effects of morphine in the spinal cord |
Q26997989 | Drug withdrawal conceptualized as a stressor. |
Q44331300 | Drug-induced GABA transporter currents enhance GABA release to induce opioid withdrawal behaviors |
Q28365395 | Effect of chronic clonidine treatment on transmitter release from sympathetic varicosities of the guinea-pig vas deferens |
Q35578528 | Effect of long-term exposure of SH-SY5Y cells to morphine: a whole cell proteomic analysis |
Q42261176 | Effect of potassium channel modulators on morphine withdrawal in mice |
Q37537366 | Effect of repeated morphine withdrawal on spatial learning, memory and serum cortisol level in mice |
Q58769343 | Effects of Ketamine on Postoperative Pain After Remifentanil-Based Anesthesia for Major and Minor Surgery in Adults: A Systematic Review and Meta-Analysis |
Q42754352 | Effects of morphine and methadone treatment on mRNA expression of Gα(i) subunits in rat brains. |
Q34104454 | Endocytosis of the mu opioid receptor reduces tolerance and a cellular hallmark of opiate withdrawal |
Q47386871 | Endogenous Gαq-Coupled Neuromodulator Receptors Activate Protein Kinase A. |
Q35048784 | Endogenous opiates and behavior: 2001. |
Q41333917 | Endomorphin-2 Decreases Excitatory Synaptic Transmission in the Spinal Ventral Horn of the Rat. |
Q90522780 | Endothelin Receptor Antagonists: Status Quo and Future Perspectives for Targeted Therapy |
Q44512657 | Endothelin receptor antagonists restore morphine analgesia in morphine tolerant rats |
Q30512265 | Enkephalin elevations contribute to neuronal and behavioral impairments in a transgenic mouse model of Alzheimer's disease |
Q34165443 | Essential role of the cAMP-cAMP response-element binding protein pathway in opiate-induced homeostatic adaptations of locus coeruleus neurons |
Q34367903 | Evaluating the effects of oral morphine on embryonic development of cerebellum in wistar rats |
Q37725365 | Evaluation of intrathecal drug delivery system for intractable pain in advanced malignancies: A prospective cohort study |
Q37077450 | Evidence for an important role of protein phosphatases in the mechanism of morphine tolerance |
Q34472770 | Examining the role of mu opioid receptor endocytosis in the beneficial and side-effects of prolonged opioid use: from a symposium on new concepts in mu-opioid pharmacology |
Q36294544 | Extracellular signal-regulated kinase (ERK) inhibition does not prevent the development or expression of tolerance to and dependence on morphine in the mouse |
Q37416451 | Extracellular signal-regulated kinase 1/2 activation counteracts morphine tolerance in the periaqueductal gray of the rat |
Q58803452 | Formation of Opioid-Induced Memory and Its Prevention: A Computational Study |
Q35264421 | Functional selectivity at the μ-opioid receptor: implications for understanding opioid analgesia and tolerance. |
Q44012210 | G-protein-gated potassium channels containing Kir3.2 and Kir3.3 subunits mediate the acute inhibitory effects of opioids on locus ceruleus neurons. |
Q44770083 | GABA release from proopiomelanocortin neurons. |
Q41507854 | GABAB receptors within the central nucleus of amygdala may involve in the morphine-induced incentive tolerance in female rats |
Q41729564 | GC-MS-based plasma metabolomic investigations of morphine dependent rats at different states of euphoria, tolerance and naloxone-precipitated withdrawal |
Q37479415 | GRIN1 regulates micro-opioid receptor activities by tethering the receptor and G protein in the lipid raft |
Q34315794 | GalR1, but not GalR2 or GalR3, levels are regulated by galanin signaling in the locus coeruleus through a cyclic AMP-dependent mechanism |
Q24523661 | Generation and characterization of Rgs4 mutant mice |
Q46727028 | Ginsenoside Rg1 restores the impairment of learning induced by chronic morphine administration in rats |
Q40611076 | Glucocorticoid feedback uncovers retrograde opioid signaling at hypothalamic synapses |
Q34144947 | How to design an opioid drug that causes reduced tolerance and dependence |
Q37433909 | Hydrogen sulfide attenuates opioid dependence by suppression of adenylate cyclase/cAMP pathway |
Q38995303 | Hydrogen sulfide inhibits opioid withdrawal-induced pain sensitization in rats by down-regulation of spinal calcitonin gene-related peptide expression in the spine. |
Q40333178 | IL-4 mediated by HSV vector suppresses morphine withdrawal response and decreases TNFα, NR2B, and pC/EBPβ in the periaqueductal gray in rats |
Q34102691 | Identification of candidate genes and gene networks specifically associated with analgesic tolerance to morphine. |
Q34776958 | Identification of morphine accumulation in the rat embryo central nervous system: a c14-morphine administration study |
Q34626916 | Identification of site of morphine action in pregnant wistar rat placenta tissue: a c(14)-morphine study |
Q36633126 | Imaging of opioid receptors in the central nervous system |
Q90185275 | Improved efficacy, tolerance, safety and abuse liability profile of the combination CR4056-morphine over morphine alone in rodent models |
Q24806600 | Increased glutamate synaptic transmission in the nucleus raphe magnus neurons from morphine-tolerant rats |
Q34065061 | Inhibition of microglial P2X4 receptors attenuates morphine tolerance, Iba1, GFAP and mu opioid receptor protein expression while enhancing perivascular microglial ED2. |
Q44132328 | Involvement of Raf-1 in chronic delta-opioid receptor agonist-mediated adenylyl cyclase superactivation |
Q44344679 | Involvement of opioid peptides and arginine-vasopressin in the regulation of water-electrolyte exchange in the amoeba Amoeba proteus |
Q34118418 | Involvement of the beta-endorphin neurons of the hypothalamic arcuate nucleus in ethanol-induced place preference conditioning in mice |
Q35104780 | It could be habit forming: drugs of abuse and striatal synaptic plasticity. |
Q30437184 | It's MORe exciting than mu: crosstalk between mu opioid receptors and glutamatergic transmission in the mesolimbic dopamine system |
Q36787595 | Kappa opioid inhibition of somatodendritic dopamine inhibitory postsynaptic currents |
Q36654621 | Ligand-biased activation of extracellular signal-regulated kinase 1/2 leads to differences in opioid induced antinociception and tolerance. |
Q34154223 | Ligand-directed trafficking of the δ-opioid receptor in vivo: two paths toward analgesic tolerance |
Q36780862 | Ligand-induced μ opioid receptor internalization in enteric neurons following chronic treatment with the opiate fentanyl |
Q44524204 | Locus-specific rescue of GluRepsilon1 NMDA receptors in mutant mice identifies the brain regions important for morphine tolerance and dependence. |
Q41952668 | Long-term changes in reward-seeking following morphine withdrawal are associated with altered N-methyl-D-aspartate receptor 1 splice variants in the amygdala |
Q44411071 | Long-term potentiation as an electrophysiological assay for morphine dependence and withdrawal in rats: an in vitro study |
Q36025329 | Mechanisms of rapid opioid receptor desensitization, resensitization and tolerance in brain neurons |
Q37924629 | Mechanisms underlying the onset and expression of levodopa-induced dyskinesia and their pharmacological manipulation. |
Q42852548 | Medial dorsal hypothalamus mediates the inhibition of reward seeking after extinction. |
Q37419004 | Membrane functional organisation and dynamic of mu-opioid receptors |
Q36792609 | Merkel Cell-Driven BDNF Signaling Specifies SAI Neuron Molecular and Electrophysiological Phenotypes. |
Q37588418 | MicroRNA-93-5p may participate in the formation of morphine tolerance in bone cancer pain mouse model by targeting Smad5. |
Q45086500 | Microglial activation involved in morphine tolerance is not mediated by toll-like receptor 4. |
Q44563662 | Modulation of GABA release during morphine withdrawal in midbrain neurons in vitro |
Q44333090 | Modulation of histone deacetylase attenuates naloxone-precipitated opioid withdrawal syndrome. |
Q37062556 | Molecular Pharmacology of δ-Opioid Receptors |
Q35579655 | Molecular mechanisms of excitatory signaling upon chronic opioid agonist treatment |
Q38726180 | Morphine Antidependence of Erythroxylum cuneatum (Miq.) Kurz in Neurotransmission Processes In Vitro |
Q44341663 | Morphine acutely regulates opioid receptor trafficking selectively in dendrites of nucleus accumbens neurons. |
Q28573514 | Morphine enhances microglial migration through modulation of P2X4 receptor signaling |
Q34776767 | Morphine induces AMPA receptor internalization in primary hippocampal neurons via calcineurin-dependent dephosphorylation of GluR1 subunits. |
Q36952367 | Morphine tolerance in the mouse ileum and colon |
Q44336809 | Morphine withdrawal enhances constitutive μ-opioid receptor activity in the ventral tegmental area. |
Q44477244 | Morphine withdrawal increases glutamate uptake and surface expression of glutamate transporter GLT1 at hippocampal synapses. |
Q24569565 | Morphine-induced changes in acetylcholine release in the interpeduncular nucleus and relationship to changes in motor behavior in rats |
Q40472238 | Morphine-induced chemotaxis and brain-derived neurotrophic factor expression in microglia. |
Q47366337 | Morphine-induced place preference affects mRNA expression of G protein α subunits in rat brain |
Q44410748 | Morphine-induced potentiation in the dentate gyrus of the hippocampus involves norepinephrine |
Q37592198 | Morphine-induced trafficking of a mu-opioid receptor interacting protein in rat locus coeruleus neurons |
Q44343229 | Mu Opioid Receptors in Gamma-Aminobutyric Acidergic Forebrain Neurons Moderate Motivation for Heroin and Palatable Food. |
Q34651031 | Mu opioid receptor A118G polymorphism in association with striatal opioid neuropeptide gene expression in heroin abusers |
Q24557501 | Mu-opioid receptors modulate the stability of dendritic spines |
Q36163576 | Multiple inhibitory G-protein-coupled receptors resist acute desensitization in the presynaptic but not postsynaptic compartments of neurons |
Q33593502 | Muscarinic acetylcholine receptor modulation of mu (mu) opioid receptors in adult rat sphenopalatine ganglion neurons |
Q34661739 | Musings on the wanderer: what's new in our understanding of vago-vagal reflexes? III. Activity-dependent plasticity in vago-vagal reflexes controlling the stomach |
Q30597308 | NF-κB signaling and vesicle transport are correlated with the reactivation of the memory trace of morphine dependence |
Q46577821 | Naloxone does not attenuate the locomotor effects of ethanol in FAST, SLOW, or two heterogeneous stocks of mice |
Q38707820 | Naloxone effects on extinction of ethanol- and cocaine-induced conditioned place preference in mice |
Q37345448 | Naltrexone Prevents in Males and Attenuates in Females the Expression of Behavioral Sensitization to Ethanol Regardless of Maternal Separation |
Q33832271 | Nerve growth factor-regulated emergence of functional delta-opioid receptors |
Q26853333 | Neural and cellular mechanisms of fear and extinction memory formation |
Q35050888 | Neuroadaptation of GABAergic transmission in the central amygdala during chronic morphine treatment |
Q34510389 | Neuroadaptive responses in brainstem noradrenergic nuclei following chronic morphine exposure |
Q44237516 | Neurokinin-1 versus mu-opioid receptor binding in rat nucleus tractus solitarius after single and recurrent intermittent hypoxia |
Q37569283 | Neuropeptide transmission in brain circuits |
Q36335668 | Neuroplasticity, axonal guidance and micro-RNA genes are associated with morphine self-administration behavior |
Q35794547 | Neurotrophins as mediators of drug effects on mood, addiction, and neuroprotection |
Q37439216 | Nicotinic and opioid receptor regulation of striatal dopamine D2-receptor mediated transmission |
Q37254437 | Nigella sativa extract affects conditioned place preference induced by morphine in rats |
Q40740343 | Nitroxidergic modulation of behavioural, cardiovascular and immune responses, and brain NADPH diaphorase activity upon morphine tolerance/dependence in rats |
Q42495896 | No effect of morphine on ventral tegmental dopamine neurons during withdrawal. |
Q39157737 | Novel Molecular Strategies and Targets for Opioid Drug Discovery for the Treatment of Chronic Pain |
Q36245077 | Nuclear factor kappaB signaling in opioid functions and receptor gene expression |
Q64944700 | Oligomerization of MrgC11 and μ-opioid receptors in sensory neurons enhances morphine analgesia. |
Q38023866 | Opiate-induced molecular and cellular plasticity of ventral tegmental area and locus coeruleus catecholamine neurons |
Q43061639 | Opiates and Plasticity in the Ventral Tegmental Area |
Q36107418 | Opioid Analgesics and P-Glycoprotein Efflux Transporters: A Potential Systems-Level Contribution to Analgesic Tolerance |
Q33796002 | Opioid and GABAB receptors differentially couple to an adenylyl cyclase/protein kinase A downstream effector after chronic morphine treatment |
Q34207011 | Opioid inhibition of N-type Ca2+ channels and spinal analgesia couple to alternative splicing |
Q42527696 | Opioid peptide receptor studies. 16. Chronic morphine alters G-protein function in cells expressing the cloned mu opioid receptor |
Q27004306 | Opioid receptor heteromers in analgesia |
Q35682951 | Opioid receptor regulation |
Q44330106 | Opioid receptors in the nucleus accumbens regulate attentional learning in the blocking paradigm. |
Q37782045 | Opioid system functional regulation in neurological disease management |
Q37065797 | Opioid tolerance development: a pharmacokinetic/pharmacodynamic perspective |
Q35049134 | Opioid tolerance in periaqueductal gray neurons isolated from mice chronically treated with morphine |
Q34563130 | Opioid tolerance-in search of the holy grail |
Q33978499 | Opioid-receptor-heteromer-specific trafficking and pharmacology |
Q64864874 | Opioidergic Modulation of Striatal Circuits, Implications in Parkinson's Disease and Levodopa Induced Dyskinesia |
Q36107411 | Opioids and efflux transporters. Part 2: P-glycoprotein substrate activity of 3- and 6-substituted morphine analogs |
Q48187662 | Opioids block long-term potentiation of inhibitory synapses |
Q44814713 | Opioids inhibit lateral amygdala pyramidal neurons by enhancing a dendritic potassium current. |
Q83225296 | Opioids modulate an emergent rhythmogenic process to depress breathing |
Q35881855 | Opioids potentiate electrical transmission at mixed synapses on the Mauthner cell |
Q43129270 | PKG and PKA signaling in LTP at GABAergic synapses |
Q93090641 | Pain And Opioid Systems, Implications In The Opioid Epidemic |
Q37679197 | Pharmacological Profiles of Oligomerized μ-Opioid Receptors |
Q33714824 | Phosphorylation of the mu-opioid receptor at tyrosine 166 (Tyr3.51) in the DRY motif reduces agonist efficacy |
Q36269197 | PolyMorphine: an innovative biodegradable polymer drug for extended pain relief |
Q44337550 | Possible involvement of mu-opioid receptors in effect of lithium on inhibitory avoidance response in mice |
Q44182452 | Potentiation of morphine analgesia by BQ123, an endothelin antagonist |
Q36970568 | Pre- and postsynaptic regulation of locus coeruleus neurons after chronic morphine treatment: a study of GIRK-knockout mice |
Q37172821 | Pre-treatment with a PKC or PKA inhibitor prevents the development of morphine tolerance but not physical dependence in mice |
Q46851483 | Presynaptic homeostatic plasticity rescues long-term depression after chronic Delta 9-tetrahydrocannabinol exposure. |
Q34749911 | Presynaptic opioid and nicotinic receptor modulation of dopamine overflow in the nucleus accumbens. |
Q42476246 | Prolonged morphine treatment selectively increases membrane recruitment of delta-opioid receptors in mouse basal ganglia |
Q36758556 | Properties and opioid inhibition of mesolimbic dopamine neurons vary according to target location |
Q41774031 | Protein kinase C phosphorylates the cAMP response element binding protein in the hypothalamic paraventricular nucleus during morphine withdrawal |
Q33355290 | Purification and mass spectrometric analysis of the kappa opioid receptor |
Q36763815 | Quantitative encoding of the effect of a partial agonist on individual opioid receptors by multisite phosphorylation and threshold detection |
Q44340203 | Quantitative single-cell differences in mu-opioid receptor mRNA distinguish myelinated and unmyelinated nociceptors. |
Q35837740 | RSK2 signaling in medial habenula contributes to acute morphine analgesia. |
Q37678223 | Randomized, placebo-controlled pilot trial of gabapentin during an outpatient, buprenorphine-assisted detoxification procedure. |
Q35174410 | Rapid dopamine transmission within the nucleus accumbens: dramatic difference between morphine and oxycodone delivery |
Q41891627 | Recovery from mu-opioid receptor desensitization after chronic treatment with morphine and methadone |
Q43972763 | Regional and cellular mapping of cAMP response element-mediated transcription during naltrexone-precipitated morphine withdrawal. |
Q34518254 | Regional expression of extracellular signal-regulated kinase 1 and 2 mRNA in a morphine-induced conditioned place preference model |
Q35172820 | Regulated endocytosis of opioid receptors: cellular mechanisms and proposed roles in physiological adaptation to opiate drugs |
Q34113042 | Regulation of opioid receptor trafficking and morphine tolerance by receptor oligomerization |
Q37719125 | Regulation of opioid receptors by endocytic membrane traffic: mechanisms and translational implications |
Q36591603 | Regulation of μ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance. |
Q35928133 | Repeated cannabinoid administration increases indices of noradrenergic activity in rats |
Q48241650 | Repeated cocaine administration impairs group II metabotropic glutamate receptor-mediated long-term depression in rat medial prefrontal cortex. |
Q36553108 | Repeated injections of orexin-A developed behavioral tolerance to its analgesic effects in rats |
Q35786247 | Reward processing by the opioid system in the brain. |
Q37162162 | Rewarding morphine-induced synaptic function of delta-opioid receptors on central glutamate synapses |
Q42486587 | Role for dopamine neurons of the rostral linear nucleus and periaqueductal gray in the rewarding and sensitizing properties of heroin |
Q46941519 | Role of PKC in regulation of Fos and TH expression after naloxone induced morphine withdrawal in the heart |
Q48566183 | Role of cAMP response element-binding protein in the rat locus ceruleus: regulation of neuronal activity and opiate withdrawal behaviors. |
Q41350890 | Role of calcium in morphine dependence and naloxone-precipitated withdrawal in mice |
Q47711187 | Role of the guanine nucleotide binding protein, Gαo, in the development of morphine tolerance and dependence |
Q44330114 | Separation of mu-opioid receptor desensitization and internalization: endogenous receptors in primary neuronal cultures. |
Q24300079 | Ser/ Thr residues at α3/β5 loop of Gαs are important in morphine-induced adenylyl cyclase sensitization but not mitogen-activated protein kinase phosphorylation |
Q26770785 | Sex Differences in Kappa Opioid Receptor Function and Their Potential Impact on Addiction |
Q33642749 | Sex differences in micro-opioid receptor expression in the rat midbrain periaqueductal gray are essential for eliciting sex differences in morphine analgesia |
Q37386501 | Shared mechanisms of alcohol and other drugs |
Q21203943 | Single dose of morphine produced a prolonged effect on dopamine neuron activities |
Q37312558 | Sleep and GABA levels in the oral part of rat pontine reticular formation are decreased by local and systemic administration of morphine. |
Q87128869 | Spatiotemporal changes in NSF expression of DRG neurons in a rat model of spinal nerve ligation |
Q44804066 | Spinal G-protein-gated K+ channels formed by GIRK1 and GIRK2 subunits modulate thermal nociception and contribute to morphine analgesia. |
Q34990529 | Striatal pre-enkephalin overexpression improves Huntington's disease symptoms in the R6/2 mouse model of Huntington's disease |
Q44100463 | Sympathetic denervation-induced changes in G protein expression in enteric neurons of the guinea pig colon |
Q33806664 | Synaptic mechanism for functional synergism between delta- and mu-opioid receptors |
Q37292487 | Synergistic anti-allodynic effect between intraperitoneal thalidomide and morphine on rat spinal nerve ligation-induced neuropathic pain |
Q33559498 | Targeted expression of μ-opioid receptors in a subset of striatal direct-pathway neurons restores opiate reward |
Q64057393 | Temporal dependence of shifts in mu opioid receptor mobility at the cell surface after agonist binding observed by single-particle tracking |
Q91796599 | The Cholinergic System as a Treatment Target for Opioid Use Disorder |
Q59807229 | The Contribution of the Descending Pain Modulatory Pathway in Opioid Tolerance |
Q41813168 | The PKs PKA and ERK 1/2 are involved in phosphorylation of TH at Serine 40 and 31 during morphine withdrawal in rat hearts |
Q42182469 | The Role of TNFα in the Periaqueductal Gray During Naloxone-Precipitated Morphine Withdrawal in Rats |
Q35400738 | The delta opioid receptor: an evolving target for the treatment of brain disorders |
Q34436808 | The effect of morphine consumption on plasma corticosteron concentration and placenta development in pregnant rats |
Q44344550 | The mu opioid receptor activation does not affect ischemia-induced agonal currents in rat spinal ventral horn |
Q38191866 | The mu-opioid receptor agonist/noradrenaline reuptake inhibition (MOR-NRI) concept in analgesia: the case of tapentadol |
Q35164063 | The neurobiology of opiate tolerance, dependence and sensitization: mechanisms of NMDA receptor-dependent synaptic plasticity |
Q89464718 | The orphan receptor GPR88 blunts the signaling of opioid receptors and multiple striatal GPCRs |
Q37830311 | The role of G protein-coupled receptors in the pathology of Alzheimer's disease |
Q37753286 | The role of functional postsynaptic NMDA receptors in the central nucleus of the amygdala in opioid dependence |
Q44350750 | The role of opioid receptor subtypes in the development of behavioral sensitization to ethanol |
Q38196854 | The μ-opioid receptor: an electrophysiologist's perspective from the sharp end. |
Q89059638 | Tolerance to Morphine-Induced Inhibition of TTX-R Sodium Channels in Dorsal Root Ganglia Neurons Is Modulated by Gut-Derived Mediators |
Q44337065 | Tolerance to repeated morphine administration is associated with increased potency of opioid agonists |
Q34359955 | Tolerance to the Antinociceptive Effect of Morphine in the Absence of Short-Term Presynaptic Desensitization in Rat Periaqueductal Gray Neurons |
Q44346788 | Two delta opioid receptor subtypes are functional in single ventral tegmental area neurons, and can interact with the mu opioid receptor |
Q44341856 | Two distinct mechanisms mediate acute mu-opioid receptor desensitization in native neurons. |
Q35562807 | Ubiquitination in the first cytoplasmic loop of μ-opioid receptors reveals a hierarchical mechanism of lysosomal down-regulation |
Q33896673 | Ultrastructural relationship between N-methyl-D-aspartate-NR1 receptor subunit and mu-opioid receptor in the mouse central nucleus of the amygdala |
Q38338668 | Understanding opioid reward |
Q58696847 | Untangling the complexity of opioid receptor function |
Q44343034 | Upregulation of mu opioid receptors by voluntary morphine administration in drinking water |
Q44070621 | Withdrawal from dependence upon butorphanol uniquely increases kappa(1)-opioid receptor binding in the rat brain |
Q44348673 | cAMP-mediated mechanisms for pain sensitization during opioid withdrawal. |
Q28551598 | mGlu2 Receptor Agonism, but Not Positive Allosteric Modulation, Elicits Rapid Tolerance towards Their Primary Efficacy on Sleep Measures in Rats |
Q28081540 | mTOR, a new potential target for chronic pain and opioid-induced tolerance and hyperalgesia |
Q34144910 | micro-Opioid receptor endocytosis prevents adaptations in ventral tegmental area GABA transmission induced during naloxone-precipitated morphine withdrawal |
Q40720739 | mu-Opioid receptors: Ligand-dependent activation of potassium conductance, desensitization, and internalization. |
Q91526138 | µ-opioid receptor-mediated downregulation of midline thalamic pathways to basal and central amygdala |
Q34939769 | β-Arrestin-2 knockout prevents development of cellular μ-opioid receptor tolerance but does not affect opioid-withdrawal-related adaptations in single PAG neurons. |
Q38285112 | μ-Opioid receptor 6-transmembrane isoform: A potential therapeutic target for new effective opioids |
Q34310081 | μ-opioid receptors: correlation of agonist efficacy for signalling with ability to activate internalization |
Search more.