Opioids modulate an emergent rhythmogenic process to depress breathing

scientific article published on 16 December 2019

Opioids modulate an emergent rhythmogenic process to depress breathing is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.7554/ELIFE.50613
P932PMC publication ID6938398
P698PubMed publication ID31841107

P50authorJack L. FeldmanQ29653556
Carolina Thörn PérezQ84155025
Xuesi M ShaoQ91488010
Kaiwen KamQ92003453
P2093author name stringSarah Heath
Xiaolu Sun
Morgan Greenwood
Nagaraj Halemani D
P2860cites workDistinct rhythm generators for inspiration and expiration in the juvenile ratQ24544195
Pre-Bötzinger Complex: a Brainstem Region that May Generate Respiratory Rhythm in MammalsQ24630958
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Mu opioid receptors on primary afferent nav1.8 neurons contribute to opiate-induced analgesia: insight from conditional knockout miceQ28533332
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Math1 is essential for the development of hindbrain neurons critical for perinatal breathingQ33637710
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μ-Opioid receptor antibody reveals tissue-dependent specific staining and increased neuronal μ-receptor immunoreactivity at the injured nerve trunk in miceQ35053136
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Opioid-induced Respiratory Depression Is Only Partially Mediated by the preBötzinger Complex in Young and Adult Rabbits In VivoQ36266355
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Pontine μ-opioid receptors mediate bradypnea caused by intravenous remifentanil infusions at clinically relevant concentrations in dogsQ36533279
G-protein-gated Inwardly Rectifying Potassium Channels Modulate Respiratory Depression by OpioidsQ36586207
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Facing the challenge of mammalian neural microcircuits: taking a few breaths may helpQ38306568
Transcriptome of neonatal preBötzinger complex neurones in Dbx1 reporter mice.Q38619105
Opioid-induced quantal slowing reveals dual networks for respiratory rhythm generationQ38971517
K(+) and Ca²(+) dependence of inspiratory-related rhythm in novel "calibrated" mouse brainstem slicesQ39838715
Substance P and opiate receptorsQ40086249
Defining preBötzinger Complex Rhythm- and Pattern-Generating Neural Microcircuits In VivoQ40586022
Design and characteristics of holographic neural photo-stimulation systemsQ43259506
Activation of opioid μ-receptors in the commissural subdivision of the nucleus tractus solitarius abolishes the ventilatory response to hypoxia in anesthetized ratsQ43890941
Opioid-resistant respiratory pathway from the preinspiratory neurones to abdominal muscles: in vivo and in vitro study in the newborn rat.Q44249866
Activation of opioid mu receptors in caudal medullary raphe region inhibits the ventilatory response to hypercapnia in anesthetized ratsQ44335841
CrossTalk proposal: The preBotzinger complex is essential for the respiratory depression following systemic administration of opioid analgesicsQ44343923
CrossTalk opposing view: The pre-Botzinger complex is not essential for respiratory depression following systemic administration of opioid analgesicsQ44343928
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Substance P and enkephalinergic synapses onto neurokinin-1 receptor-immunoreactive neurons in the pre-Bötzinger complex of ratsQ44747840
Modulation of respiratory rhythm in vitro: role of Gi/o protein-mediated mechanismsQ44993227
Asymmetric control of inspiratory and expiratory phases by excitability in the respiratory network of neonatal mice in vitro.Q46030002
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Respiratory Network Stability and Modulatory Response to Substance P Require NalcnQ47924706
Hindbrain interneurons and axon guidance signaling critical for breathingQ48102533
Modulation of respiratory rhythmogenesis by chloride-mediated conductances during the perinatal period.Q48592372
Structure-function analysis of rhythmogenic inspiratory pre-Bötzinger complex networks in "calibrated" newborn rat brainstem slicesQ48637341
Statistical power analyses using G*Power 3.1: tests for correlation and regression analyses.Q51777217
Functional imaging, spatial reconstruction, and biophysical analysis of a respiratory motor circuit isolated in vitro.Q54487015
Cell Type-Dependent Activation Sequence During Rhythmic Bursting in the PreBötzinger Complex in Respiratory Rhythmic Slices From MiceQ58767297
Biophysical mechanisms in the mammalian respiratory oscillator re-examined with a new data-driven computational modelQ64054870
Trpm4 ion channels in pre-Bötzinger complex interneurons are essential for breathing motor pattern but not rhythmQ64121152
Effects of naloxone on carotid body chemoreception and ventilation in the catQ71581914
Differential responses of respiratory nuclei to anoxia in rhythmic brain stem slices of miceQ73181909
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Non-nociceptive roles of opioids in the CNS: opioids' effects on neurogenesis, learning, memory and affectQ90288944
Differential impact of two critical respiratory centres in opioid-induced respiratory depression in awake miceQ90557765
Brainstem Circuits Controlling Action DiversificationQ91710654
P4510describes a project that usesImageJQ1659584
P407language of work or nameEnglishQ1860
P921main subjectRhythm GenerationQ10854806
P577publication date2019-12-16
P1433published ineLifeQ2000008
P1476titleOpioids modulate an emergent rhythmogenic process to depress breathing
P478volume8

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cites work (P2860)
Q114008480Breathing Rhythm and Pattern and Their Influence on Emotion
Q90044433Emergent Elements of Inspiratory Rhythmogenesis: Network Synchronization and Synchrony Propagation
Q112697297Prostaglandin E2 Exerts Biphasic Dose Response on the PreBötzinger Complex Respiratory-Related Rhythm
Q95269816Receptor-centric solutions for the opioid epidemic: Making the opioid user impervious to overdose death
Q112707176Transcriptomes of electrophysiologically recorded Dbx1-derived respiratory neurons of the preBötzinger complex in neonatal mice

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