It could be habit forming: drugs of abuse and striatal synaptic plasticity.

scientific article

It could be habit forming: drugs of abuse and striatal synaptic plasticity. is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1016/S0166-2236(03)00065-1
P698PubMed publication ID12689769

P50authorCarl R LupicaQ64779171
P2093author name stringDavid M Lovinger
John G Partridge
Gregory L Gerdeman
P2860cites workAddiction and the brain: The neurobiology of compulsion and its persistenceQ22337278
Addiction, dopamine, and the molecular mechanisms of memoryQ28142501
Presynaptic mechanisms underlying cannabinoid inhibition of excitatory synaptic transmission in rat striatal neuronsQ28363375
Limbic activation during cue-induced cocaine cravingQ28369526
Drug addiction, dysregulation of reward, and allostasisQ29616741
Getting formal with dopamine and rewardQ29618725
Molecular basis of long-term plasticity underlying addictionQ29620539
Addiction, a Disease of Compulsion and Drive: Involvement of the Orbitofrontal CortexQ30039756
Localization and mechanisms of action of cannabinoid receptors at the glutamatergic synapses of the mouse nucleus accumbens.Q31813503
CB1 cannabinoid receptor inhibits synaptic release of glutamate in rat dorsolateral striatumQ31817073
Acetylcholine-mediated modulation of striatal functionQ33838308
Dopaminergic modulation of neuronal excitability in the striatum and nucleus accumbensQ33904968
Amphetamine blocks long-term synaptic depression in the ventral tegmental area.Q33911049
Single cocaine exposure in vivo induces long-term potentiation in dopamine neuronsQ33949219
Alterations in dopaminergic and glutamatergic transmission in the induction and expression of behavioral sensitization: a critical review of preclinical studiesQ34022916
Endogenous cannabinoids mediate long-term synaptic depression in the nucleus accumbensQ34032832
Local circuit neurons in the striatum regulate neural and behavioral responses to dopaminergic stimulationQ34066535
Levodopa-induced dyskinesias and dopamine-dependent stereotypies: a new hypothesisQ34070894
Long-term depression in the nucleus accumbens: a neural correlate of behavioral sensitization to cocaineQ34100505
Activation of group I mGluRs is necessary for induction of long-term depression at striatal synapsesQ34100802
Endogenous nicotinic cholinergic activity regulates dopamine release in the striatumQ34102291
Toward a neurobiology of obsessive-compulsive disorderQ34122154
Cellular and synaptic adaptations mediating opioid dependence.Q34127771
Learning and memory functions of the Basal GangliaQ34132332
Dopaminergic control of synaptic plasticity in the dorsal striatumQ34206258
Rewarding actions of phencyclidine and related drugs in nucleus accumbens shell and frontal cortexQ34378202
Cannabinoids inhibit excitatory inputs to neurons in the shell of the nucleus accumbens: an in vivo electrophysiological studyQ34524477
Multiple parallel memory systems in the brain of the rat.Q34534214
Extrinsic connections of the basal gangliaQ34570614
Long-term potentiation of excitatory inputs to brain reward areas by nicotine.Q51381056
Post-receptor mechanisms underlying striatal long-term depression.Q51627778
Building neural representations of habits.Q52030807
Regional and postnatal heterogeneity of activity-dependent long-term changes in synaptic efficacy in the dorsal striatum.Q52165392
Dopamine and cAMP-regulated phosphoprotein 32 kDa controls both striatal long-term depression and long-term potentiation, opposing forms of synaptic plasticityQ63256021
Striatonigrostriatal Pathways in Primates Form an Ascending Spiral from the Shell to the Dorsolateral StriatumQ64356882
Inhibitory control of the GABAergic transmission in the rat neostriatum by D2 dopamine receptorsQ73465262
Effects of chronic delta9-tetrahydrocannabinol on rat midbrain dopamine neurons: an electrophysiological assessmentQ73500317
Activation of D2-like dopamine receptors reduces synaptic inputs to striatal cholinergic interneuronsQ73575678
Presynaptic nicotinic receptors modulating dopamine release in the rat striatumQ73689125
Neuronal localization of cannabinoid receptors in the basal ganglia of the rat.Q34602111
Psychomotor stimulant addiction: a neural systems perspective.Q34616133
Cannabinoid addiction: behavioral models and neural correlates.Q34616145
Dopamine-dependent synaptic plasticity in striatum during in vivo developmentQ34658296
Dopamine-dependent plasticity of corticostriatal synapsesQ34951521
Visual habit formation in monkeys with neurotoxic lesions of the ventrocaudal neostriatumQ35060219
Decreased probability of neurotransmitter release underlies striatal long-term depression and postnatal development of corticostriatal synapsesQ36054269
The nucleus accumbens as a complex of functionally distinct neuronal ensembles: an integration of behavioural, electrophysiological and anatomical data.Q36724640
The functional anatomy of disorders of the basal gangliaQ40400049
Repeated cocaine administration alters the electrophysiological properties of prefrontal cortical neuronsQ41006104
The corticostriatal projection: from synaptic plasticity to dysfunctions of the basal gangliaQ41095947
Dopamine activation of endogenous cannabinoid signaling in dorsal striatumQ41646203
Modulation of long-term synaptic plasticity at excitatory striatal synapsesQ41648201
Long-term synaptic depression in the striatum: physiological and pharmacological characterizationQ42453585
A measure of striatal function predicts motor stereotypy.Q42485259
Bi-directional changes in synaptic plasticity induced at corticostriatal synapses in vitroQ42498386
Alterations in behaviour and glutamate transmission following presentation of stimuli previously associated with cocaine exposureQ42517807
Motivational effects of ethanol in DARPP-32 knock-out mice.Q43517475
Direct actions of cannabinoids on synaptic transmission in the nucleus accumbens: a comparison with opioidsQ43517979
Dopamine D-1/D-5 receptor activation is required for long-term potentiation in the rat neostriatum in vitroQ43517989
Progression of changes in dopamine transporter binding site density as a result of cocaine self-administration in rhesus monkeys.Q43578199
Selective involvement of mGlu1 receptors in corticostriatal LTD.Q43621325
Amphetamine-induced plasticity of AMPA receptors in the ventral tegmental area: effects on extracellular levels of dopamine and glutamate in freely moving rats.Q43697282
A cellular mechanism of reward-related learning.Q43729267
The circuitry mediating cocaine-induced reinstatement of drug-seeking behavior.Q43770574
Cocaine and amphetamine depress striatal GABAergic synaptic transmission through D2 dopamine receptorsQ43854201
Long-lasting potentiation of GABAergic synapses in dopamine neurons after a single in vivo ethanol exposure.Q43918814
Synaptic mechanisms underlie nicotine-induced excitability of brain reward areasQ43925474
Cooperative endocannabinoid production by neuronal depolarization and group I metabotropic glutamate receptor activationQ43936608
Nicotinic acetylcholine receptors interact with dopamine in induction of striatal long-term depression.Q43940157
Postsynaptic endocannabinoid release is critical to long-term depression in the striatumQ43971441
Knockout of ERK1 MAP kinase enhances synaptic plasticity in the striatum and facilitates striatal-mediated learning and memoryQ44025656
Endocannabinoids facilitate the induction of LTP in the hippocampusQ44038905
Concurrent activation of dopamine D1 and D2 receptors is required to evoke neural and behavioral phenotypes of cocaine sensitization.Q44067042
Dopamine release in the dorsal striatum during cocaine-seeking behavior under the control of a drug-associated cue.Q44067046
A neostriatal habit learning system in humans.Q45979314
Simultaneous LTP of non-NMDA- and LTD of NMDA-receptor-mediated responses in the nucleus accumbensQ46076587
Modulation of synaptic transmission by dopamine and norepinephrine in ventral but not dorsal striatumQ46332683
Expression of long-term potentiation of the striatum in methamphetamine-sensitized ratsQ48167848
In vivo induction of striatal long-term potentiation by low-frequency stimulation of the cerebral cortexQ48172736
A critical role of the nitric oxide/cGMP pathway in corticostriatal long-term depression.Q48257417
Endocannabinoids: endogenous cannabinoid receptor ligands with neuromodulatory actionQ48309971
Modifications of reward expectation-related neuronal activity during learning in primate striatumQ48410939
Inhibition of GABAergic inhibitory postsynaptic currents by cannabinoids in rat corpus striatum.Q48452719
Pre- and postsynaptic inhibition by opioids in rat striatumQ48602658
Decreased frequency but not amplitude of quantal synaptic responses associated with expression of corticostriatal long-term depressionQ48617011
A postsynaptic interaction between dopamine D1 and NMDA receptors promotes presynaptic inhibition in the rat nucleus accumbens via adenosine release.Q48658263
D1 receptor activation enhances evoked discharge in neostriatal medium spiny neurons by modulating an L-type Ca2+ conductance.Q48723732
P433issue4
P921main subjectstriatumQ1319792
synaptic plasticityQ1551556
P304page(s)184-192
P577publication date2003-04-01
P1433published inTrends in NeurosciencesQ3538443
P1476titleIt could be habit forming: drugs of abuse and striatal synaptic plasticity
P478volume26

Reverse relations

cites work (P2860)
Q44853701A critical interaction between dopamine D2 receptors and endocannabinoids mediates the effects of cocaine on striatal gabaergic Transmission
Q36741898A neuropeptide-centric view of psychostimulant addiction
Q36293916A scale-free systems theory of motivation and addiction
Q28680729A unified framework for addiction: vulnerabilities in the decision process
Q40711119Accelerated habit formation following amphetamine exposure is reversed by D1, but enhanced by D2, receptor antagonists
Q48617548Acute amphetamine down-regulates RGS4 mRNA and protein expression in rat forebrain: distinct roles of D1 and D2 dopamine receptors
Q47225379Acute and chronic modulation of striatal endocannabinoid-mediated plasticity by nicotine
Q37333137Adaptations in AMPA receptor transmission in the nucleus accumbens contributing to incubation of cocaine craving
Q22251215Addiction-related gene regulation: risks of exposure to cognitive enhancers vs. other psychostimulants
Q52690614Alcohol exposure disrupts mu opioid receptor-mediated long-term depression at insular cortex inputs to dorsolateral striatum.
Q88111070Alcohol induces input-specific aberrant synaptic plasticity in the rat dorsomedial striatum
Q22241964Alcoholism: A Systems Approach From Molecular Physiology to Addictive Behavior
Q46244129Alteration of eating behaviors in patients with Parkinson's disease: possibly overlooked?
Q38650103Alterations in brain activation in response to prolonged morphine withdrawal-induced behavioral inflexibility in rats.
Q48570291Alterations of rat corticostriatal synaptic plasticity after chronic ethanol exposure and withdrawal
Q67496261Amphetamine Self-Administration and Its Extinction Alter the 5-HT1B Receptor Protein Levels in Designated Structures of the Rat Brain.
Q83229805An open cortico-basal ganglia loop allows limbic control over motor output via the nigrothalamic pathway
Q48257640Anandamide regulates postnatal development of long-term synaptic plasticity in the rat dorsolateral striatum.
Q34549925Automaticity and reestablishment of executive control-an fMRI study
Q35987786BDNF Val(66)Met genotype is associated with drug-seeking phenotypes in heroin-dependent individuals: a pilot study
Q35164109BDNF interacts with endocannabinoids to regulate cocaine-induced synaptic plasticity in mouse midbrain dopamine neurons.
Q44686798Behavioral and neurochemical vulnerability during adolescence in mice: studies with nicotine
Q27024840Binge eating disorder and food addiction
Q46049773Brain regions related to tool use and action knowledge reflect nicotine dependence
Q40169667Brain uptake and utilization of fatty acids, lipids and lipoproteins: application to neurological disorders
Q43016890Brain-derived neurotrophic factor controls cannabinoid CB1 receptor function in the striatum.
Q36061698Calcium-permeable AMPA receptors in the VTA and nucleus accumbens after cocaine exposure: when, how, and why?
Q37160448Cannabis, cannabinoids and schizophrenia: integration of the evidence
Q90721121Cell-type and projection-specific dopaminergic encoding of aversive stimuli in addiction
Q37247103Cellular events in nicotine addiction
Q45067725Changes in endocannabinoid levels in a rat model of behavioural sensitization to morphine
Q38809530Chronic Nicotine Alters Corticostriatal Plasticity in the Striatopallidal Pathway Mediated By NR2B-Containing Silent Synapses
Q36910784Chronic nicotine treatment impacts the regulation of opioid and non-opioid peptides in the rat dorsal striatum
Q96120892Circuits that encode and guide alcohol-associated preference
Q46112878Cocaine self-administration selectively abolishes LTD in the core of the nucleus accumbens.
Q37491532Cocaine-induced changes of synaptic transmission in the striatum are modulated by adenosine A2A receptors and involve the tyrosine phosphatase STEP.
Q38124448Comorbid substance use disorder in schizophrenia: a selective overview of neurobiological and cognitive underpinnings
Q44336174Compartment-specific modulation of GABAergic synaptic transmission by mu-opioid receptor in the mouse striatum with green fluorescent protein-expressing dopamine islands.
Q62887568Complex Control of Striatal Neurotransmission by Nicotinic Acetylcholine Receptors via Excitatory Inputs onto Medium Spiny Neurons
Q64230853Compulsivity in Alcohol Use Disorder and Obsessive Compulsive Disorder: Implications for Neuromodulation
Q46866063Context-specific reversal of cocaine sensitization by the CB1 cannabinoid receptor antagonist rimonabant
Q33823748Cortical and basal ganglia contributions to habit learning and automaticity
Q37885420Cortico-basal ganglia mechanisms for overcoming innate, habitual and motivational behaviors
Q45306738Corticostriatal synaptic function in mouse models of Huntington's disease: early effects of huntingtin repeat length and protein load
Q31042532Decreased spontaneous eye blink rates in chronic cannabis users: evidence for striatal cannabinoid-dopamine interactions
Q30498533Deficiency in Endocannabinoid Signaling in the Nucleus Accumbens Induced by Chronic Unpredictable Stress
Q33247797Delay aversion but preference for large and rare rewards in two choice tasks: implications for the measurement of self-control parameters.
Q36535614Dicer loss in striatal neurons produces behavioral and neuroanatomical phenotypes in the absence of neurodegeneration
Q64928689Differences in Nicotine Encoding Dopamine Release between the Striatum and Shell Portion of the Nucleus Accumbens.
Q37000735Differences in excitatory transmission between thalamic and cortical afferents to single spiny efferent neurons of rat dorsal striatum
Q33821444Differences in response initiation and behavioral flexibility between adolescent and adult rats
Q35141659Different neural substrates mediate cocaine seeking after abstinence versus extinction training: a critical role for the dorsolateral caudate-putamen
Q33258602Differential effect of cannabinoid agonists and endocannabinoids on histamine release from distinct regions of the rat brain
Q38234309Direct and indirect pathways of basal ganglia: a critical reappraisal
Q28592654Disrupted motor learning and long-term synaptic plasticity in mice lacking NMDAR1 in the striatum
Q44770106Disruption of endocannabinoid release and striatal long-term depression by postsynaptic blockade of endocannabinoid membrane transport.
Q48590755Distinct roles for spinophilin and neurabin in dopamine-mediated plasticity
Q47125735Do Cannabinoids Confer Neuroprotection Against Epilepsy? An Overview
Q35941665Dopamine mechanisms and cocaine reward
Q46279749Dopamine modulation of state-dependent endocannabinoid release and long-term depression in the striatum.
Q30354575Dopamine signaling architecture in Caenorhabditis elegans.
Q42652289Dopamine signaling in dorsal versus ventral striatum: the dynamic role of cholinergic interneurons.
Q26798176Dopaminergic Regulation of Striatal Interneurons in Reward and Addiction: Focus on Alcohol
Q34626864Dorsal striatum mediation of cocaine-seeking after withdrawal from short or long daily access cocaine self-administration in rats
Q36718457Drug Addiction in Patients With Chronic Schizophrenia and Its Relation With Psychopathology and Impulsiveness
Q37310301Drug-Induced Alterations of Endocannabinoid-Mediated Plasticity in Brain Reward Regions
Q24657705EEG biofeedback as a treatment for substance use disorders: review, rating of efficacy, and recommendations for further research
Q47647739Effect of repeated abstinence on chronic ethanol self-administration in the rhesus monkey
Q55171928Effect of traumatic brain injury on nicotine-induced modulation of dopamine release in the striatum and nucleus accumbens shell.
Q34329874Electrophysiological and structural alterations in striatum associated with behavioral sensitization to (±)3,4-methylenedioxymethamphetamine (Ecstasy) in rats: role of drug context.
Q35772531Electrophysiological evidence of alterations to the nucleus accumbens and dorsolateral striatum during chronic cocaine self-administration
Q24672367Emerging roles for endocannabinoids in long‐term synaptic plasticity
Q34967151Endocannabinoid signaling in midbrain dopamine neurons: more than physiology?
Q41978739Endocannabinoid signaling is critical for habit formation
Q42508054Endocannabinoid-mediated rescue of striatal LTD and motor deficits in Parkinson's disease models
Q35129752Enhanced striatal dopamine release during food stimulation in binge eating disorder
Q46573395Ethanol induces long-term facilitation of NR2B-NMDA receptor activity in the dorsal striatum: implications for alcohol drinking behavior.
Q35146203Ethanol modulation of synaptic plasticity
Q30490427Ethanol-BDNF interactions: still more questions than answers.
Q52313974Ethanol-Induced Taurine Elevation in the Rat Dorsal Striatum.
Q36398915Ethanol-mediated facilitation of AMPA receptor function in the dorsomedial striatum: implications for alcohol drinking behavior.
Q35577736Ethanol-mediated long-lasting adaptations of the NR2B-containing NMDA receptors in the dorsomedial striatum
Q45103776Evidence for the role of nitric oxide in nicotine-induced locomotor sensitization in mice
Q33268100Expression of Cre recombinase in dopaminoceptive neurons
Q37728136Expression pattern of neural synaptic plasticity marker-Arc in different brain regions induced by conditioned drug withdrawal from acute morphine-dependent rats
Q37258557Extracellular recordings of rodents in vivo: their contribution to integrative neuroscience
Q35155391Extracellular signal-regulated kinase signaling in the ventral tegmental area mediates cocaine-induced synaptic plasticity and rewarding effects
Q34650334Frequency-specific and D2 receptor-mediated inhibition of glutamate release by retrograde endocannabinoid signaling
Q37386566From actions to habits: neuroadaptations leading to dependence
Q44545264Functional localization of cannabinoid receptors and endogenous cannabinoid production in distinct neuron populations of the hippocampus.
Q44495428Functional tolerance and blockade of long-term depression at synapses in the nucleus accumbens after chronic cannabinoid exposure.
Q38739255Future Research Directions in the Positive Valence Systems: Measurement, Development, and Implications for Youth Unipolar Depression
Q37003653Gene expression of opioid and dopamine systems in mouse striatum: effects of CB1 receptors, age and sex.
Q39138814Gene expression profiling in the striatum of amphetamine-treated spontaneously hypertensive rats which showed amphetamine conditioned place preference and self-administration
Q37170603Gene-environment interactions affect long-term depression (LTD) through changes in dopamine receptor affinity in Snap25 deficient mice.
Q30540374Habitual alcohol seeking: time course and the contribution of subregions of the dorsal striatum
Q37395798High on habits
Q28593050Identification of PSD-95 as a regulator of dopamine-mediated synaptic and behavioral plasticity
Q36491440Impulsivity, compulsivity, and habit: the role of orbitofrontal cortex revisited
Q48118197Impulsivity-related brain volume deficits in schizophrenia-addiction comorbidity
Q37094864In vivo (1)H magnetic resonance spectroscopy in young-adult daily marijuana users.
Q41904475In vivo cocaine experience generates silent synapses.
Q48421523Increased occupancy of dopamine receptors in human striatum during cue-elicited cocaine craving
Q27023237Individual differences in response to positive and negative stimuli: endocannabinoid-based insight on approach and avoidance behaviors
Q34472949Interactions between Procedural Learning and Cocaine Exposure Alter Spontaneous and Cortically Evoked Spike Activity in the Dorsal Striatum
Q44544255Interrelations between monoaminergic afferents and corticotropin-releasing factor-immunoreactive neurons in the rat central amygdaloid nucleus: ultrastructural evidence for dopaminergic control of amygdaloid stress systems
Q52145787Involvement of Inhibitory Receptors in Modulating Dopamine Signaling and Synaptic Activity Following Acute Ethanol Exposure in Striatal Subregions.
Q22337342LTP and LTD
Q30496867Long-lasting adaptations of the NR2B-containing NMDA receptors in the dorsomedial striatum play a crucial role in alcohol consumption and relapse.
Q42568290Loss of cocaine locomotor response in Pitx3-deficient mice lacking a nigrostriatal pathway
Q24671514Marijuana and cannabinoid regulation of brain reward circuits
Q36959855Mechanisms of disease: basic-research-driven investigations in humans--the case of hyperkinetic disorders
Q35440613Methamphetamine induces alterations in the long non-coding RNAs expression profile in the nucleus accumbens of the mouse
Q42504114Methamphetamine, morphine, and their combination: acute changes in striatal dopaminergic transmission evaluated by microdialysis in awake rats
Q38318237Methylphenidate administration to adolescent rats determines plastic changes on reward-related behavior and striatal gene expression
Q30409196MicroRNAs in addiction: adaptation's middlemen?
Q38297689Microarray analysis reveals distinctive signaling between the bed nucleus of the stria terminalis, nucleus accumbens, and dorsal striatum
Q37535559Molecular basis for catecholaminergic neuron diversity
Q33736491Morphine Reward Promotes Cue-Sensitive Learning: Implication of Dorsal Striatal CREB Activity
Q36784503Morphine produces circuit-specific neuroplasticity in the bed nucleus of the stria terminalis
Q46881179Motor-skill learning-associated gene regulation in the striatum: effects of cocaine
Q33946237Natural reward-related learning in rats with neonatal ventral hippocampal lesions and prior cocaine exposure.
Q36832206Neurofeedback training for opiate addiction: improvement of mental health and craving
Q43706480Neuronal development genes are key elements mediating the reinforcing effects of methamphetamine, amphetamine, and methylphenidate
Q36137598Neuronal nicotinic acetylcholine receptors: neuroplastic changes underlying alcohol and nicotine addictions
Q34350092Neuropathological consequences of prenatal cocaine exposure in the mouse.
Q22251110Neuropharmacology of alcohol addiction
Q30493991Neuropharmacology of the endocannabinoid signaling system-molecular mechanisms, biological actions and synaptic plasticity.
Q36335668Neuroplasticity, axonal guidance and micro-RNA genes are associated with morphine self-administration behavior
Q37680104Neurotransmitter roles in synaptic modulation, plasticity and learning in the dorsal striatum
Q36582014New insights on neurobiological mechanisms underlying alcohol addiction
Q45006435Nicotine-associated cues maintain nicotine-seeking behavior in rats several weeks after nicotine withdrawal: reversal by the cannabinoid (CB1) receptor antagonist, rimonabant (SR141716).
Q30540975Nonassociative learning as gated neural integrator and differentiator in stimulus-response pathways
Q28476651Opiate sensitization induces FosB/ΔFosB expression in prefrontal cortical, striatal and amygdala brain regions
Q43061639Opiates and Plasticity in the Ventral Tegmental Area
Q35776806Orexin-1 receptor mediation of cocaine seeking in male and female rats
Q42235808Overexpression of Shati/Nat8l, an N-acetyltransferase, in the nucleus accumbens attenuates the response to methamphetamine via activation of group II mGluRs in mice
Q37705771Parental THC exposure leads to compulsive heroin-seeking and altered striatal synaptic plasticity in the subsequent generation.
Q37664482Partial nicotinic acetylcholine (alpha4beta2) agonists as promising new medications for smoking cessation
Q41857105Pathway-Specific Striatal Substrates for Habitual Behavior
Q33255884Post- versus presynaptic plasticity in L-DOPA-induced dyskinesia
Q36074911Prefrontal and limbic resting state brain network functional connectivity differs between nicotine-dependent smokers and non-smoking controls.
Q30582194Prefrontal cortical and striatal transcriptional responses to the reinforcing effect of repeated methylphenidate treatment in the spontaneously hypertensive rat, animal model of attention-deficit/hyperactivity disorder (ADHD).
Q37014100Presynaptic nicotinic receptors: a dynamic and diverse cholinergic filter of striatal dopamine neurotransmission
Q60952522Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization
Q36252830Psychostimulants, L-type calcium channels, kinases, and phosphatases
Q42453077Psychostimulants, Protein phosphorylation and Gene expression: a growing role of L-type calcium channels
Q36211464Psychostimulants, madness, memory... and RGS proteins?
Q33947686Reactivation of cocaine reward memory engages the Akt/GSK3/mTOR signaling pathway and can be disrupted by GSK3 inhibition
Q42450816Region-specific impairments in striatal synaptic transmission and impaired instrumental learning in a mouse model of Angelman syndrome
Q41518121Reinforcement determines the timing dependence of corticostriatal synaptic plasticity in vivo
Q34458303Removing pathogenic memories: a neurobiology of psychotherapy
Q34768885Repeated exposure to methamphetamine causes long-lasting presynaptic corticostriatal depression that is renormalized with drug readministration
Q40435396Ric-8B, an olfactory putative GTP exchange factor, amplifies signal transduction through the olfactory-specific G-protein Galphaolf.
Q37193626Rodent models for compulsive alcohol intake
Q48535179Role of dopamine in the primate caudate nucleus in reward modulation of saccades.
Q37249385Role of movement in long-term basal ganglia changes: implications for abnormal motor responses
Q37160440Roles of micro-opioid receptors in GABAergic synaptic transmission in the striosome and matrix compartments of the striatum
Q28571603Roles of two subtypes of corticotrophin‐releasing factor receptor in the corticostriatal long‐term potentiation under cocaine withdrawal condition
Q90776578Shared striatal activity in decisions to satisfy curiosity and hunger at the risk of electric shocks
Q34629089Signaling pathways involved in striatal synaptic plasticity are sensitive to temporal pattern and exhibit spatial specificity
Q46387394Singing to the tune of dopamine. Focus on "Properties of dopamine release and uptake in the songbird basal ganglia".
Q41618301Striatal fast-spiking interneurons selectively modulate circuit output and are required for habitual behavior.
Q35747217Striatal involvement in human alcoholism and alcohol consumption, and withdrawal in animal models
Q43813771Striatal modulation of BDNF expression using microRNA124a-expressing lentiviral vectors impairs ethanol-induced conditioned-place preference and voluntary alcohol consumption
Q37336143Striatal plasticity and basal ganglia circuit function
Q28392093Striatal signal transduction and drug addiction
Q40936456Striatopallidal Neuron NMDA Receptors Control Synaptic Connectivity, Locomotor, and Goal-Directed Behaviors
Q36295499Structural and behavioral correlates of abnormal encoding of money value in the sensorimotor striatum in cocaine addiction
Q34374573Substrate-based fragment identification for the development of selective, nonpeptidic inhibitors of striatal-enriched protein tyrosine phosphatase
Q28506626Subunit composition of functional nicotinic receptors in dopaminergic neurons investigated with knock-out mice
Q47308721Synaptic adaptations to chronic ethanol intake in male rhesus monkey dorsal striatum depend on age of drinking onset
Q35356742Synaptic and morphological neuroadaptations in the putamen associated with long-term, relapsing alcohol drinking in primates
Q28242702Synaptic plasticity: multiple forms, functions, and mechanisms
Q37040227Synaptic targets of Δ9-tetrahydrocannabinol in the central nervous system.
Q39623917Temporal Rewiring of Striatal Circuits Initiated by Nicotine.
Q64229781The Endocannabinoid System and Cannabidiol's Promise for the Treatment of Substance Use Disorder
Q33771966The Hepatocyte Growth Factor/c-Met Antagonist, Divalinal-Angiotensin IV, Blocks the Acquisition of Methamphetamine Dependent Conditioned Place Preference in Rats
Q38344063The dissection of transcriptional modules regulated by various drugs of abuse in the mouse striatum
Q44268415The effects of acute ethanol exposure and ageing on rat brain glutathione metabolism.
Q35876026The endocannabinoid system and its therapeutic exploitation
Q24648473The endocannabinoid system as an emerging target of pharmacotherapy
Q29615356The molecular logic of endocannabinoid signalling
Q37885892The prevalence and clinical characteristics of punding in Parkinson's disease.
Q34700186The role of acetylcholine in cocaine addiction.
Q34641435The role of dorsal vs ventral striatal pathways in cocaine-seeking behavior after prolonged abstinence in rats
Q38698930The role of habit in compulsivity
Q45017073The role of prefrontal cortex D1-like and D2-like receptors in cocaine-seeking behavior in rats
Q48368959The role of protein synthesis in striatal long-term depression.
Q29619829The role of the basal ganglia in habit formation
Q30499665The small-conductance calcium-activated potassium channel is a key modulator of firing and long-term depression in the dorsal striatum
Q36228104Therapeutic implications of the mGluR theory of fragile X mental retardation
Q37150613Tolerance to Ethanol or Nicotine Results in Increased Ethanol Self-Administration and Long-Term Depression in the Dorsolateral Striatum
Q46782244Trk: a neuromodulator of age-specific behavioral and neurochemical responses to cocaine in mice
Q48402642Up-regulation of dopamine D(2)L mRNA levels in the ventral tegmental area and dorsal striatum of amphetamine-sensitized C57BL/6 mice: role of Ca(v)1.3 L-type Ca(2+) channels.
Q36875681Using metabotropic glutamate receptors to modulate cocaine's synaptic and behavioral effects: mGluR1 finds a niche
Q34660703Voluntary exercise and sucrose consumption enhance cannabinoid CB1 receptor sensitivity in the striatum
Q37375116Voluntary oral nicotine intake in mice down-regulates GluR2 but does not modulate depression-like behaviors
Q37424880mRNA changes in nucleus accumbens related to methamphetamine addiction in mice

Search more.