Patient-derived xenograft models in gynecologic malignancies

scientific article

Patient-derived xenograft models in gynecologic malignancies is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.14694/EDBOOK_AM.2014.34.E258
P932PMC publication ID4156101
P698PubMed publication ID24857111

P50authorPaul HaluskaQ87036002
P2093author name stringClare L Scott
Helen J Mackay
P2860cites workComparison of established cell lines at different passages by karyotype and comparative genomic hybridizationQ23921272
Orthotopic Xenograft Model of Cervical Cancer for Studying Microenvironmental Effects on Metastasis Formation and Response to Drug TreatmentQ61872230
The kinetics of recovery in irradiated colonic mucosa of the mouseQ69817031
Preclinical phase II studies in human tumor xenografts: a European multicenter follow-up studyQ72160214
Radiation therapy with and without extrafascial hysterectomy for bulky stage IB cervical carcinoma: a randomized trial of the Gynecologic Oncology GroupQ73507149
Concurrent chemotherapy and pelvic radiation therapy compared with pelvic radiation therapy alone as adjuvant therapy after radical surgery in high-risk early-stage cancer of the cervixQ73675166
HEIGHTENED IMMUNITY AND SUSCEPTIBILITY TOWARD CHEEK POUCH HETEROGRAFTS OF A MOUSE LEUKEMIA IN SYRIAN HAMSTERSQ76617591
Pelvic radiation with concurrent chemotherapy compared with pelvic and para-aortic radiation for high-risk cervical cancerQ77321070
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancerQ77321076
Evaluation of monoclonal humanized anti-HER2 antibody, trastuzumab, in patients with recurrent or refractory ovarian or primary peritoneal carcinoma with overexpression of HER2: a phase II trial of the Gynecologic Oncology GroupQ78785334
Establishment of subrenal capsule xenografts of primary human ovarian tumors in SCID mice: potential modelsQ81120942
Pravastatin Inhibits the Rho/CCN2/extracellular matrix cascade in human fibrosis explants and improves radiation-induced intestinal fibrosis in ratsQ81310319
Commentary on the clinical trial reported by: Tewari KS, Sill M, Long III HJ, et al. Incorporation of bevacizumab in the treatment of recurrent and metastatic cervical cancer: a phase III randomized trial of the Gynecologic Oncology Group. J Clin OnQ87054592
Patient-derived tumour xenografts as models for oncology drug developmentQ24604068
Efficient tumour formation by single human melanoma cellsQ24648938
Patient-derived xenograft models to improve targeted therapy in epithelial ovarian cancer treatmentQ26829125
One mouse, one patient paradigm: New avatars of personalized cancer therapyQ27023342
Integrated genomic analyses of ovarian carcinomaQ27860518
Phenotypic instability of Saos-2 cells in long-term cultureQ28254879
Integrated genomic characterization of endometrial carcinomaQ28289962
Wnt activity defines colon cancer stem cells and is regulated by the microenvironmentQ29618024
BRCA1/2 mutation analysis in 41 ovarian cell lines reveals only one functionally deleterious BRCA1 mutationQ33930051
Landscape of genomic alterations in cervical carcinomasQ34169464
Primary tumour genetic alterations and intra-tumoral heterogeneity are maintained in xenografts of human colon cancers showing chromosome instability.Q34490295
Phenotypic heterogeneity and instability of human ovarian tumor-initiating cellsQ34836634
Pathway-specific differences between tumor cell lines and normal and tumor tissue cellsQ35129156
Molecular correlates of platinum response in human high-grade serous ovarian cancer patient-derived xenograftsQ35448716
Loss of imprinting of IGF2 and not H19 in breast cancer, adjacent normal tissue and derived fibroblast culturesQ36899265
Evaluation of early and late toxicities in chemoradiation trials.Q36935098
Hormonal therapies and gynaecological cancersQ36947766
Characterization of the Tumor-Microenvironment in Patient-Derived Cervix Xenografts (OCICx)Q37017045
Evaluating cell lines as tumour models by comparison of genomic profilesQ37025950
Tumorgrafts as in vivo surrogates for women with ovarian cancer.Q37626455
Oncogenic mutations in cervical cancer: genomic differences between adenocarcinomas and squamous cell carcinomas of the cervixQ37678092
Hepatobiliary cystadenoma with mesenchymal stromaQ38137801
The need for improvement of the treatment of advanced and metastatic cervical cancer, the rationale for combined chemo-immunotherapyQ38163007
Human thyroid tumor cell lines derived from different tumor types present a common dedifferentiated phenotypeQ40084367
Development of a quantitative Correlative Light Electron Microscopy technique to study GLUT4 traffickingQ41609333
Paracrine/autocrine regulation of breast cancer by the insulin-like growth factorsQ41727237
Establishment of a cell line (Co-115) from a human colon carcinoma transplanted into nude miceQ42039616
Biological Characterization of Human Epithelial Ovarian Carcinoma Cells in Primary Culture: The Insulin-like Growth Factor SystemQ42817129
Establishment and characterization of cancer cell cultures and xenografts derived from primary or metastatic Mullerian cancers.Q44308450
Xenografts of primary human gynecological tumors grown under the renal capsule of NOD/SCID mice show genetic stability during serial transplantation and respond to cytotoxic chemotherapyQ46244368
Phase II evaluation of imatinib mesylate in the treatment of recurrent or persistent epithelial ovarian or primary peritoneal carcinoma: a Gynecologic Oncology Group StudyQ46494607
Phase II study of gefitinib in patients with relapsed or persistent ovarian or primary peritoneal carcinoma and evaluation of epidermal growth factor receptor mutations and immunohistochemical expression: a Gynecologic Oncology Group StudyQ46630310
A human ovarian carcinoma murine xenograft model useful for preclinical trialsQ46787985
Hedgehog pathway signaling in cervical carcinoma and outcome after chemoradiationQ54342333
The ability to form primary tumor xenografts is predictive of increased risk of disease recurrence in early-stage non-small cell lung cancer.Q54632436
Response of mouse intestine to neutrons and gamma rays in relation to dose fractionation and division cycleQ54753977
Intraperitoneal and subcutaneous xenografts of human ovarian carcinoma in nude mice and their potential in experimental therapyQ60043794
P921main subjectpatientQ181600
xenograftQ64148587
P304page(s)e258-66
P577publication date2014-01-01
P1433published inAmerican Society of Clinical Oncology educational book / ASCOQ26842316
P1476titlePatient-derived xenograft models in gynecologic malignancies

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cites work (P2860)
Q58549406A patient derived xenograft model of cervical cancer and cervical dysplasia
Q37558633A patient-derived-xenograft platform to study BRCA-deficient ovarian cancers
Q36750564Cell line and patient-derived xenograft models reveal elevated CDCP1 as a target in high-grade serous ovarian cancer.
Q37272622Histologic and molecular analysis of patient derived xenografts of high-grade serous ovarian carcinoma
Q98777898Human-Derived Model Systems in Gynecological Cancer Research
Q38705019Modeling of Patient-Derived Xenografts in Colorectal Cancer
Q38508812Ovarian and cervical cancer patient derived xenografts: The past, present, and future.
Q36414048Ovarian carcinoma patient derived xenografts reproduce their tumor of origin and preserve an oligoclonal structure
Q58768056Patient-Derived Xenograft Models for Endometrial Cancer Research
Q33842769Prevention of Human Lymphoproliferative Tumor Formation in Ovarian Cancer Patient-Derived Xenografts
Q36326279The PARP inhibitor olaparib enhances the sensitivity of Ewing sarcoma to trabectedin
Q35771750The promise and challenge of ovarian cancer models
Q35586693The safety and efficacy of single-agent pemetrexed in platinum-resistant advanced urothelial carcinoma: a large single-institution experience
Q38257126Translational research in oncology--10 years of progress and future prospects

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