Xenografts of primary human gynecological tumors grown under the renal capsule of NOD/SCID mice show genetic stability during serial transplantation and respond to cytotoxic chemotherapy

scientific article

Xenografts of primary human gynecological tumors grown under the renal capsule of NOD/SCID mice show genetic stability during serial transplantation and respond to cytotoxic chemotherapy is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.YGYNO.2008.03.011
P698PubMed publication ID18547621
P5875ResearchGate publication ID5308796

P50authorC. Blake GilksQ90823350
P2093author name stringDavid G Huntsman
Y Z Wang
Dianne M Miller
Hui Xue
Jessica N McAlpine
Alessandro De Luca
Melinda A Miller
Joshua Z Press
Jennifer A Kenyon
P2860cites workSignificance analysis of microarrays applied to the ionizing radiation responseQ24606608
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategyQ27860519
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymeraseQ28131711
Ovarian carcinomas with genetic and epigenetic BRCA1 loss have distinct molecular abnormalitiesQ33315604
Cancer of the ovaryQ34375262
Retrospective review of 208 patients with leiomyosarcoma of the uterus: prognostic indicators, surgical management, and adjuvant therapyQ35150629
Morphological effects of chemotherapy on ovarian carcinomaQ35585946
Targeting the DNA repair defect of BRCA tumoursQ36162913
Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activationQ42497877
Anti-inflammatory effects of a novel, potent inhibitor of poly (ADP-ribose) polymeraseQ43839560
Phase I clinical trial of recombinant human endostatin administered as a short intravenous infusion repeated daily.Q44135089
The therapeutic effects of PJ34 [N-(6-oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide.HCl], a selective inhibitor of poly(ADP-ribose) polymerase, in experimental allergic encephalomyelitis are associated with immunomodulation.Q44907854
Mouse models of gynecologic pathologyQ46510692
Antiangiogenic therapy of experimental cancer does not induce acquired drug resistanceQ50626711
Human Tumor Xenografts as Predictive Preclinical Models for Anticancer Drug Activity in Humans: Better than Commonly Perceived—But They Can Be ImprovedQ56865079
Gene Expression Profiles of Serous, Endometrioid, and Clear Cell Subtypes of Ovarian and Endometrial CancerQ62112715
Clinicopathologic features of BRCA-linked and sporadic ovarian cancerQ73782102
Histopathologic assessment of tumor regression after neoadjuvant chemotherapy in advanced-stage ovarian cancerQ80070141
Histopathologic assessment of chemotherapy effects in epithelial ovarian cancer patients treated with neoadjuvant chemotherapy and delayed primary surgical debulkingQ80300655
Establishment of subrenal capsule xenografts of primary human ovarian tumors in SCID mice: potential modelsQ81120942
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectcytotoxicityQ246181
chemotherapyQ974135
xenograftQ64148587
P304page(s)256-264
P577publication date2008-06-10
P1433published inGynecologic OncologyQ5625182
P1476titleXenografts of primary human gynecological tumors grown under the renal capsule of NOD/SCID mice show genetic stability during serial transplantation and respond to cytotoxic chemotherapy
P478volume110

Reverse relations

cites work (P2860)
Q30839218A class of extracellular vesicles from breast cancer cells activates VEGF receptors and tumour angiogenesis.
Q36123789Biobanking of patient and patient-derived xenograft ovarian tumour tissue: efficient preservation with low and high fetal calf serum based methods
Q35592388Conventional chemotherapy and oncogenic pathway targeting in ovarian carcinosarcoma using a patient-derived tumorgraft
Q64969004Current Status of Patient-Derived Ovarian Cancer Models.
Q50938903Establishment and characterization of uterine sarcoma and carcinosarcoma patient-derived xenograft models.
Q39176960Establishment of a novel experimental model of human angiosarcoma and a VEGF-targeting therapeutic experiment
Q34776859Establishment of human patient-derived endometrial cancer xenografts in NOD scid gamma mice for the study of invasion and metastasis
Q64101398Gene expression differences between matched pairs of ovarian cancer patient tumors and patient-derived xenografts
Q37272622Histologic and molecular analysis of patient derived xenografts of high-grade serous ovarian carcinoma
Q98777898Human-Derived Model Systems in Gynecological Cancer Research
Q28742873Identification of novel therapeutic targets in microdissected clear cell ovarian cancers
Q38221430Imaging preclinical tumour models: improving translational power
Q47825939Intravital biobank and personalized cancer therapy: the correlation with omics.
Q26786724Molecular and clinical implementations of ovarian cancer mouse avatar models
Q35448716Molecular correlates of platinum response in human high-grade serous ovarian cancer patient-derived xenografts
Q21195204Molecular profiling of patient-derived breast cancer xenografts
Q39673894Next generation patient-derived prostate cancer xenograft models
Q38508812Ovarian and cervical cancer patient derived xenografts: The past, present, and future.
Q38722976Patient-Derived Xenograft Models of Epithelial Ovarian Cancer for Preclinical Studies.
Q34125001Patient-derived human tumour tissue xenografts in immunodeficient mice: a systematic review
Q34141193Patient-derived xenograft models in gynecologic malignancies
Q26829125Patient-derived xenograft models to improve targeted therapy in epithelial ovarian cancer treatment
Q92462041Patient-derived xenografts of different grade gliomas retain the heterogeneous histological and genetic features of human gliomas
Q38317188Patient-derived xenografts recapitulate molecular features of human uveal melanomas
Q41533087Prognostic relevance of a T-type calcium channels gene signature in solid tumours: A correlation ready for clinical validation
Q33898564Stability of preclinical models of aggressive renal cell carcinomas
Q52799875The allosteric AKT inhibitor, MK2206, decreases tumor growth and invasion in patient derived xenografts of endometrial cancer
Q24630783Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes
Q37626455Tumorgrafts as in vivo surrogates for women with ovarian cancer.
Q30409503Using heterogeneity of the patient-derived xenograft model to identify the chemoresistant population in ovarian cancer

Search more.