Tropomyosin ends determine the stability and functionality of overlap and troponin T complexes

scientific article

Tropomyosin ends determine the stability and functionality of overlap and troponin T complexes is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0006-3495(03)70042-3
P932PMC publication ID1302878
P698PubMed publication ID12719247

P2093author name stringSarah E Hitchcock-DeGregori
Norma J Greenfield
Thomas Palm
P2860cites workTropomyosin requires an intact N-terminal coiled coil to interact with tropomodulinQ24537515
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
Deciphering the design of the tropomyosin moleculeQ27632998
Solution NMR structure and folding dynamics of the N terminus of a rat non-muscle alpha-tropomyosin in an engineered chimeric proteinQ27635078
The structure of the N-terminus of striated muscle alpha-tropomyosin in a chimeric peptide: nuclear magnetic resonance structure and circular dichroism studiesQ27757862
The leucine zipper: a hypothetical structure common to a new class of DNA binding proteinsQ27860587
Use of T7 RNA polymerase to direct expression of cloned genesQ27860692
Disease-causing mutations in cardiac troponin T: identification of a critical tropomyosin-binding regionQ28199174
Vertebrate tropomyosin: distribution, properties and functionQ28216589
The effects of troponin T fragments T1 and T2 on the binding of nonpolymerizable tropomyosin to F-actin in the presence and absence of troponin I and troponin CQ28301614
The amino terminus of muscle tropomyosin is a major determinant for functionQ28306422
Structure and interactions of the carboxyl terminus of striated muscle alpha-tropomyosin: it is important to be flexibleQ34179208
Relationship between alternatively spliced exons and functional domains in tropomyosinQ37620352
Functional alpha-tropomyosin produced in Escherichia coli. A dipeptide extension can substitute the amino-terminal acetyl groupQ38309278
The effect of single residue substitutions of serine-283 on the strength of head-to-tail interaction and actin binding properties of rabbit skeletal muscle alpha-tropomyosinQ38311803
The sequence of the alternatively spliced sixth exon of alpha-tropomyosin is critical for cooperative actin binding but not for interaction with troponinQ38343182
Tropomyosin isoforms in nonmuscle cells.Q41322774
Requirement of amino-terminal modification for striated muscle alpha-tropomyosin functionQ41441330
The ends of tropomyosin are major determinants of actin affinity and myosin subfragment 1-induced binding to F-actin in the open state.Q42616670
Actomyosin regulatory properties of yeast tropomyosin are dependent upon N-terminal modificationQ42634794
Regulatory properties of tropomyosin effects of length, isoform, and N-terminal sequenceQ42651874
The effect of N-terminal acetylation on the structure of an N-terminal tropomyosin peptide and alpha alpha-tropomyosinQ42768993
Van't Hoff and calorimetric enthalpies from isothermal titration calorimetry: are there significant discrepancies?Q43591623
CD and (13)C(alpha)-NMR studies of folding equilibria in a two-stranded coiled coil formed by residues 190-254 of alpha-tropomyosinQ43688054
Roles for the troponin tail domain in thin filament assembly and regulation. A deletional study of cardiac troponin T.Q47982729
The stability of tropomyosin, a two-stranded coiled-coil protein, is primarily a function of the hydrophobicity of residues at the helix-helix interface.Q52320819
In vitro functional characterization of bacterially expressed human fibroblast tropomyosin isoforms and their chimeric mutants.Q52406122
Effects of the amino-terminal regions of tropomyosin and troponin T on thin filament assemblyQ52409793
Quantitative analysis of protein far UV circular dichroism spectra by neural networksQ52423418
Alternatively spliced exons of the β tropomyosin gene exhibit different affinities for F-actin and effects with nonmuscle caldesmonQ52537151
Interaction of tropomyosin-troponin with actin filaments.Q52734249
Mapping the functional domains within the carboxyl terminus of alpha-tropomyosin encoded by the alternatively spliced ninth exon.Q54593386
The structure of the amino terminus of tropomyosin is critical for binding to actin in the absence and presence of troponin.Q54750069
Altered actin and troponin binding of amino-terminal variants of chicken striated muscle alpha-tropomyosin expressed in Escherichia coli.Q54763296
Tropomyosin coiled-coil interactions: Evidence for an unstaggered structureQ67341522
Tropomyosin lysine reactivities and relationship to coiled-coil structureQ69958745
Ca2+-dependent binding of synthetic peptides corresponding to some regions of troponin-I to troponin-CQ70402967
Expression of smooth muscle and nonmuscle tropomyosins in Escherichia coli and characterization of bacterially produced tropomyosinsQ70622133
Non-polymerizable tropomyosin: Preparation, some properties and F-actin bindingQ70935113
Changes in actin lysine reactivities during polymerization detected using a competitive labeling methodQ71624627
Amino acid sequence of equine platelet tropomyosin. Correlation with interaction propertiesQ71737758
Structural stability of short subsequences of the tropomyosin chainQ72110195
Some functional properties of nonpolymerizable and polymerizable tropomyosinQ72788027
Cooperative interactions between adjacent troponin-tropomyosin complexes may be transmitted through the actin filamentQ72854689
A micro biuret method for protein determination; determination of total protein in cerebrospinal fluidQ73417380
van't Hoff and calorimetric enthalpies II: effects of linked equilibriaQ74226426
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)3181-3189
P577publication date2003-05-01
P1433published inBiophysical JournalQ2032955
P1476titleTropomyosin ends determine the stability and functionality of overlap and troponin T complexes
P478volume84

Reverse relations

cites work (P2860)
Q35902629A small molecule inhibitor of tropomyosin dissociates actin binding from tropomyosin-directed regulation of actin dynamics
Q24301265A troponin T mutation that causes infantile restrictive cardiomyopathy increases Ca2+ sensitivity of force development and impairs the inhibitory properties of troponin
Q34277909Alterations at the cross-bridge level are associated with a paradoxical gain of muscle function in vivo in a mouse model of nemaline myopathy
Q44728813Ca2+-induced rolling of tropomyosin in muscle thin filaments: the alpha- and beta-band hypothesis revisited
Q37151138Cardiac muscle activation blunted by a mutation to the regulatory component, troponin T
Q42267863Cooperative regulation of myosin-S1 binding to actin filaments by a continuous flexible Tm-Tn chain
Q42183635Different effects of trifluoroethanol and glycerol on the stability of tropomyosin helices and the head-to-tail complex.
Q52676165Distinct sites in tropomyosin specify shared and isoform-specific regulation of myosins II and V.
Q44590900Effects of tropomyosin internal deletion Delta23Tm on isometric tension and the cross-bridge kinetics in bovine myocardium.
Q50354214First profiling of lysine crotonylation of myofilament proteins and ribosomal proteins in zebrafish embryos
Q36898618Functional homodimers and heterodimers of recombinant smooth muscle tropomyosin
Q39310653Historical perspective on heart function: the Frank-Starling Law.
Q37365592Localization of the binding interface between leiomodin-2 and α-tropomyosin
Q36534070Molecular effects of familial hypertrophic cardiomyopathy-related mutations in the TNT1 domain of cTnT.
Q47705176Molecular mechanisms and structural features of cardiomyopathy-causing troponin T mutants in the tropomyosin overlap region
Q92218433Moving beyond simple answers to complex disorders in sarcomeric cardiomyopathies: the role of integrated systems
Q37749050New insights into the regulation of the actin cytoskeleton by tropomyosin
Q41854642On/off-switchable LSPR nano-immunoassay for troponin-T.
Q28287468Perturbed length-dependent activation in human hypertrophic cardiomyopathy with missense sarcomeric gene mutations
Q28555047Recruitment Kinetics of Tropomyosin Tpm3.1 to Actin Filament Bundles in the Cytoskeleton Is Independent of Actin Filament Kinetics
Q28909751Structure and tropomyosin binding properties of the N-terminal capping domain of tropomodulin 1.
Q27653518Structure of the N Terminus of a Nonmuscle α-Tropomyosin in Complex with the C Terminus: Implications for Actin Binding † ‡
Q27661607Structure of the Tropomyosin Overlap Complex from Chicken Smooth Muscle: Insight into the Diversity of N-Terminal Recognition,
Q47591174Temperature sensitive point mutations in fission yeast tropomyosin have long range effects on the stability and function of the actin-tropomyosin copolymer
Q39094600Tropomyosin Structure, Function, and Interactions: A Dynamic Regulator
Q75366742Tropomyosin exon 6b is troponin-specific and required for correct acto-myosin regulation
Q42926452Tropomyosin period 3 is essential for enhancement of isometric tension in thin filament-reconstituted bovine myocardium
Q38439597Ultra short yeast tropomyosins show novel myosin regulation
Q42566843Using circular dichroism collected as a function of temperature to determine the thermodynamics of protein unfolding and binding interactions

Search more.