Phase III study of pemetrexed in combination with cisplatin versus cisplatin alone in patients with malignant pleural mesothelioma

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Phase III study of pemetrexed in combination with cisplatin versus cisplatin alone in patients with malignant pleural mesothelioma is …
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scholarly articleQ13442814

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P356DOI10.1200/JCO.2003.11.136
P698PubMed publication ID12860938

P50authorNicholas J. VogelzangQ7025647
P2093author name stringClet Niyikiza
Michael Boyer
Christian Manegold
Ulrich Gatzemeier
Claude Denham
E Kaukel
James J Rusthoven
James Symanowski
Paolo Paoletti
Pierre Ruffie
Salih Emri
P433issue14
P407language of work or nameEnglishQ1860
P921main subjectpatientQ181600
cisplatinQ412415
P304page(s)2636-2644
P577publication date2003-07-01
P1433published inJournal of Clinical OncologyQ400292
P1476titlePhase III study of pemetrexed in combination with cisplatin versus cisplatin alone in patients with malignant pleural mesothelioma
P478volume21

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Q41340663Evaluation of intracavitary administration of curcumin for the treatment of sarcomatoid mesothelioma
Q46612586Evaluation of pemetrexed (Alimta, LY231514) as second line chemotherapy in persistent or recurrent carcinoma of the cervix: a phase II study of the Gynecologic Oncology Group
Q45928394Evaluation of pemetrexed (Alimta, LY231514) as second-line chemotherapy in persistent or recurrent carcinoma of the cervix: the CERVIX 1 study of the MITO (Multicentre Italian Trials in Ovarian Cancer and Gynecologic Malignancies) Group.
Q47127588Ex vivo evaluation of tumor cell specific drug responses in malignant pleural effusions
Q37686318Exemestane blocks mesothelioma growth through downregulation of cAMP, pCREB and CD44 implicating new treatment option in patients affected by this disease
Q37214250Existing models, but not neutrophil-to-lymphocyte ratio, are prognostic in malignant mesothelioma
Q61709331Expertenempfehlung 2006 zur rationalen Zweitlinien-Therapie beim nicht-kleinzelligen Bronchuskarzinom
Q47096401Exploring the characteristics of patients with mesothelioma who chose active symptom control over chemotherapy as first-line treatment: a prospective, observational, single centre study
Q92439627Exposure-Response Analysis of Overall Survival for Tremelimumab in Unresectable Malignant Mesothelioma: The Confounding Effect of Disease Status
Q39236993Expression and role of GLUT-1, MCT-1, and MCT-4 in malignant pleural mesothelioma
Q42335278Expression and therapeutic significance of estrogen receptor β in malignant pleural mesothelioma
Q47948817Expression of ALCAM (CD166) and PD-L1 (CD274) independently predicts shorter survival in malignant pleural mesothelioma
Q39298123Expression of Wilms' tumor gene (WT1) is associated with survival in malignant pleural mesothelioma.
Q38437441Expression of bcl-2 family members in malignant pleural mesothelioma
Q39933225Expression of the embryonic lethal abnormal vision-like protein HuR in human mesothelioma: association with cyclooxygenase-2 and prognosis
Q40483522Extended Pleurectomy-Decortication-Based Treatment for Advanced Stage Epithelial Mesothelioma Yielding a Median Survival of Nearly Three Years.
Q47759752Extended pleurectomy decortication for malignant pleural mesothelioma in the elderly: the need for an inclusive yet selective approach
Q35782796Extrapleural pneumonectomy in the treatment of epithelioid malignant pleural mesothelioma: novel prognostic implications of combined N1 and N2 nodal involvement based on experience in 529 patients
Q41847770FAS and FASL genetic polymorphisms impact on clinical outcome of malignant pleural mesothelioma
Q89017219FDG PET-derived parameters as prognostic tool in progressive malignant pleural mesothelioma treated patients
Q51617036FDG PET/CT patterns of treatment failure of malignant pleural mesothelioma: relationship to histologic type, treatment algorithm, and survival.
Q35678085Factors associated with survival in a large series of patients with malignant pleural mesothelioma in New South Wales
Q44610633Factors influencing long-term survival in mesothelioma patients--results of the German mesothelioma register
Q43128653Feasibility study of dose-dense biweekly administered pemetrexed in patients with non-small cell lung cancer.
Q35751860Feasibility study of two schedules of sunitinib in combination with pemetrexed in patients with advanced solid tumors
Q50850318Febuxostat exerts dose-dependent renoprotection in rats with cisplatin-induced acute renal injury.
Q38959812Fibroblast growth factor receptor inhibition is active against mesothelioma and synergizes with radio- and chemotherapy.
Q28389185Fibulin-3 as a biomarker of response to treatment in malignant mesothelioma
Q24628879Fibulin-3 as a blood and effusion biomarker for pleural mesothelioma
Q34679620Fine-Needle Aspiration Biopsies for Gene Expression Ratio-Based Diagnostic and Prognostic Tests in Malignant Pleural Mesothelioma
Q35832320First-line chemotherapy with liposomal doxorubicin plus cisplatin for patients with advanced malignant pleural mesothelioma: phase II trial.
Q47868774First-line chemotherapy with pemetrexed plus cisplatin for malignant peritoneal mesothelioma
Q37449024First-line treatment in advanced non-small-cell lung cancer: the emerging role of the histologic subtype
Q39018529Folates provoke cellular efflux and drug resistance of substrates of the multidrug resistance protein 1 (MRP1).
Q36821171Folylpoly-glutamate synthetase expression is associated with tumor response and outcome from pemetrexed-based chemotherapy in malignant pleural mesothelioma
Q34669260Fool's gold, lost treasures, and the randomized clinical trial
Q55221451Four immunohistochemical assays to measure the PD-L1 expression in malignant pleural mesothelioma.
Q37180702Four-gene expression ratio test for survival in patients undergoing surgery for mesothelioma
Q36354734From methotrexate to pemetrexed and beyond. A review of the pharmacodynamic and clinical properties of antifolates
Q38870857Functional differences between wild-type and mutant-type BRCA1-associated protein 1 tumor suppressor against malignant mesothelioma cells
Q37449036Future developments in the management of malignant pleural mesothelioma
Q33690709GAS5 long non-coding RNA in malignant pleural mesothelioma.
Q37243005Gemcitabine and cisplatin in unresectable malignant mesothelioma of the pleura: a phase II study of the Southwest Oncology Group (SWOG 9810)
Q54698040Gemcitabine and vinorelbine as second-line or beyond treatment in patients with malignant pleural mesothelioma pretreated with platinum plus pemetrexed chemotherapy.
Q33378691Gemcitabine and vinorelbine in pemetrexed-pretreated patients with malignant pleural mesothelioma
Q37052430Gemcitabine combined with oxaliplatin in pretreated patients with malignant pleural mesothelioma: an observational study
Q28384371Gender-Specific Molecular and Clinical Features Underlie Malignant Pleural Mesothelioma
Q38079969Gene therapy for malignant mesothelioma: current prospects and challenges
Q48294725Generalized eczema craquelé (asteatotic dermatitis) associated with pemetrexed treatment.
Q33899105Genes associated with prognosis after surgery for malignant pleural mesothelioma promote tumor cell survival in vitro
Q35699080Genetically Engineered Oncolytic Newcastle Disease Virus Effectively Induces Sustained Remission of Malignant Pleural Mesothelioma
Q40176023Genomic profiling of malignant pleural mesothelioma with array-based comparative genomic hybridization shows frequent non-random chromosomal alteration regions including JUN amplification on 1p32.
Q38555471Glucocorticoids and Cancer.
Q28394028Guidelines for the diagnosis and treatment of malignant pleural mesothelioma
Q48292976HSP90 inhibition alters the chemotherapy-driven rearrangement of the oncogenic secretome.
Q33645607Harnessing the potential synergy of combining radiation therapy and immunotherapy for thoracic malignancies
Q48394328Health-related quality of life and inflammatory markers in malignant pleural mesothelioma
Q55311618Heat shock protein 90 inhibitors augment endogenous wild-type p53 expression but down-regulate the adenovirally-induced expression by inhibiting a proteasome activity.
Q26799894Hedgehog Signaling in Malignant Pleural Mesothelioma
Q41262195Hemithoracic radiation therapy after extrapleural pneumonectomy for malignant pleural mesothelioma: Toxicity and outcomes at an Australian institution
Q55481165Heterogeneity in Immune Cell Content in Malignant Pleural Mesothelioma.
Q88924373Heterogeneity in Malignant Pleural Mesothelioma
Q37662700Histone deacetylase inhibitors in malignant pleural mesothelioma: preclinical rationale and clinical trials
Q90198734How I treat malignant pleural mesothelioma
Q36259724Human agonistic TRAIL receptor antibodies Mapatumumab and Lexatumumab induce apoptosis in malignant mesothelioma and act synergistically with cisplatin.
Q40421611Human and mouse mesotheliomas exhibit elevated AKT/PKB activity, which can be targeted pharmacologically to inhibit tumor cell growth
Q62392158Hyponatraemia is a predictor of clinical outcome for malignant pleural mesothelioma
Q34241413Identification and functional impact of homo-oligomers of the human proton-coupled folate transporter
Q89457615Identification of a CD8+ T-cell response to a predicted neoantigen in malignant mesothelioma
Q98735838Identification of a Five-Gene Signature for Predicting Survival in Malignant Pleural Mesothelioma Patients
Q103740398Identification of the prognostic and immunotherapeutic potential of L antigen family member 3 in malignant pleural mesothelioma
Q36862865Identifying the target NSCLC patient for maintenance therapy: an analysis from a placebo-controlled, phase III trial of maintenance pemetrexed (H3E-MC-JMEN).
Q35649214Imaging and therapy of malignant pleural mesothelioma using replication-competent herpes simplex viruses.
Q38717244Immune checkpoint blockade in malignant mesothelioma: A novel therapeutic strategy against a deadly disease?
Q38212149Immune therapies for malignant mesothelioma
Q38022807Immunotherapies for non-small-cell lung cancer and mesothelioma.
Q33645613Immunotherapy and radiation therapy for malignant pleural mesothelioma.
Q38180749Immunotherapy for malignant pleural mesothelioma. Current status and future prospects
Q33890551Immunotherapy for malignant pleural mesothelioma: current status and future directions
Q90612209Immunotherapy for mesothelioma: a critical review of current clinical trials and future perspectives
Q38390104Immunotherapy prospects in the treatment of lung cancer and mesothelioma
Q90782085Immunotherapy trials in mesothelioma - promising results, but don't stop here
Q39728506Impact of Age on Long-Term Outcomes of Surgery for Malignant Pleural Mesothelioma
Q96131716Impact of hypoxia on chemoresistance of mesothelioma mediated by the proton-coupled folate transporter, and preclinical activity of new anti-LDH-A compounds
Q33877584Improved Outcomes with Modern Lung-Sparing Trimodality Therapy in Patients with Malignant Pleural Mesothelioma.
Q36322368Improved survival after introduction of chemotherapy for malignant pleural mesothelioma in Slovenia: Population-based survey of 444 patients
Q85364510In Reply
Q52559185In Silico and In Vitro Analyses of LncRNAs as Potential Regulators in the Transition from the Epithelioid to Sarcomatoid Histotype of Malignant Pleural Mesothelioma (MPM).
Q90383407In Vitro Characterization of Cisplatin and Pemetrexed Effects in Malignant Pleural Mesothelioma 3D Culture Phenotypes
Q36180331In Vitro and In Vivo Antitumor Activity of [Pt(O,O'-acac)(γ-acac)(DMS)] in Malignant Pleural Mesothelioma
Q80396496In vitro chemosensitivity of freshly explanted tumor cells to pemetrexed is correlated with target gene expression
Q33890506In vitro experimental models of mesothelioma revisited
Q33665367In vitro study on the schedule-dependency of the interaction between pemetrexed, gemcitabine and irradiation in non-small cell lung cancer and head and neck cancer cells
Q37880216Inactivation of Merlin in malignant mesothelioma cells and the Hippo signaling cascade dysregulation
Q39769492Incidence of interstitial lung disease in patients with mesothelioma in the west part of Japan
Q60395357Increased sensitivity to apoptosis upon endoplasmic reticulum stress-induced activation of the unfolded protein response in chemotherapy-resistant malignant pleural mesothelioma
Q39818881Individualizing Mesothelioma Treatment: Small Steps Into a Brighter Future
Q53990140Indolent peritoneal mesothelioma: PI3K-mTOR inhibitors as a novel therapeutic strategy.
Q39350596Induction chemotherapy vs post-operative adjuvant therapy for malignant pleural mesothelioma
Q33400437Induction chemotherapy, extrapleural pneumonectomy, and adjuvant radiotherapy for malignant pleural mesothelioma: experience of Guy's and St Thomas' hospitals
Q34616107Induction chemotherapy, extrapleural pneumonectomy, and postoperative high-dose radiotherapy for locally advanced malignant pleural mesothelioma: a phase II trial.
Q37090789Inflammation in malignant mesothelioma - friend or foe?
Q49835562Influence of Pleurectomy and Decortication in Health-Related Quality of Life Among Patients with Malignant Pleural Mesothelioma
Q93039466Inherited predisposition to malignant mesothelioma and overall survival following platinum chemotherapy
Q90167838Inhibition of EZH2 methyltransferase decreases immunoediting of mesothelioma cells by autologous macrophages through a PD-1-dependent mechanism
Q37457703Inhibition of FGF/FGFR autocrine signaling in mesothelioma with the FGF ligand trap, FP-1039/GSK3052230.
Q36557343Inhibition of autophagy potentiates pemetrexed and simvastatin-induced apoptotic cell death in malignant mesothelioma and non-small cell lung cancer cells
Q94552713Inhibition of miR-18a-3p reduces proliferation of mesothelioma cells and sensitizes them to cisplatin
Q42369564Inhibition of the Polyamine Synthesis Pathway Is Synthetically Lethal with Loss of Argininosuccinate Synthase 1.
Q38429562Inhibition of the spindle assembly checkpoint kinase Mps-1 as a novel therapeutic strategy in malignant mesothelioma.
Q51416101Inhibition of yes-associated protein down-regulates PD-L1 (CD274) expression in human malignant pleural mesothelioma.
Q55088639Integrated analysis of somatic mutations and immune microenvironment in malignant pleural mesothelioma.
Q57153508Intensity-modulated radiotherapy is a safe and effective treatment for localized malignant pleural mesothelioma
Q34974037Interferon-β produces synergistic combinatory anti-tumor effects with cisplatin or pemetrexed on mesothelioma cells
Q53586030Interim results of pleurectomy/decortication and intraoperative intrapleural hyperthermic cisplatin perfusion for patients with malignant pleural mesothelioma intolerable to extrapleural pneumonectomy.
Q91949972Interplay of non-coding RNAs and approved antimetabolites such as gemcitabine and pemetrexed in mesothelioma
Q38221769Interventional therapies for malignant pleural effusions: the present and the future.
Q38849618Intracellular lactate-mediated induction of estrogen receptor beta (ERβ) in biphasic malignant pleural mesothelioma cells.
Q39438165Intraoperative adjuncts for malignant pleural mesothelioma
Q34293068Investigational approaches for mesothelioma
Q91123540Ipilimumab and nivolumab in the treatment of recurrent malignant pleural mesothelioma (INITIATE): results of a prospective, single-arm, phase 2 trial
Q38647275Is immunotherapy a viable option in treating mesothelioma?
Q88913091Is there a role for immunotherapy in malignant pleural mesothelioma?
Q59137560Is there a role for prophylactic radiotherapy to intervention tract sites in patients with malignant pleural mesothelioma?
Q36063077Joint modeling of longitudinal outcomes and survival using latent growth modeling approach in a mesothelioma trial
Q35540770Joint modeling of multiple longitudinal patient-reported outcomes and survival
Q44173242Kinetics of soluble mesothelin in patients with malignant pleural mesothelioma during treatment.
Q39043614LIM-domain protein AJUBA suppresses malignant mesothelioma cell proliferation via Hippo signaling cascade
Q36490313Lapatinib enhances trastuzumab-mediated antibody-dependent cellular cytotoxicity via upregulation of HER2 in malignant mesothelioma cells
Q49232092Large-scale copy number analysis reveals variations in genes not previously associated with malignant pleural mesothelioma.
Q37629910Late cutaneous metastases to the face from malignant pleural mesothelioma: a case report and review of the literature
Q28395597Latest developments in our understanding of the pathogenesis of mesothelioma and the design of targeted therapies
Q93048382Liquid Biopsy in Malignant Pleural Mesothelioma: State of the Art, Pitfalls, and Perspectives
Q38255347Local and systemic therapies for malignant pleural mesothelioma
Q57452854Local cancer recurrence: The realities, challenges, and opportunities for new therapies
Q81608122Localized malignant mesothelioma in the middle mediastinum: report of a case
Q34970431Long non coding RNAs (lncRNAs) are dysregulated in Malignant Pleural Mesothelioma (MPM).
Q36417109Long-term results in malignant pleural mesothelioma treated with neoadjuvant chemotherapy, extrapleural pneumonectomy and intensity-modulated radiotherapy
Q26849259Looking up: Recent advances in understanding and treating peritoneal carcinomatosis
Q47653923Loss of functional BAP1 augments sensitivity to TRAIL in cancer cells
Q85640217Loss of mesothelin expression by mesothelioma cells grown in vitro determines sensitivity to anti-mesothelin immunotoxin SS1P
Q64907367Low-dose cyclophosphamide depletes circulating naïve and activated regulatory T cells in malignant pleural mesothelioma patients synergistically treated with dendritic cell-based immunotherapy.
Q81086287Lung cancer
Q36328370Lung cancer: Biology and treatment options
Q83464539Lymph node dissection in primary intrahepatic malignant mesothelioma: case report and implications for diagnosis and therapy
Q31019143MDM2 and HIF1alpha expression levels in different histologic subtypes of malignant pleural mesothelioma: correlation with pathological and clinical data
Q27853125MDM2 is an important prognostic and predictive factor for platin-pemetrexed therapy in malignant pleural mesotheliomas and deregulation of P14/ARF (encoded by CDKN2A) seems to contribute to an MDM2-driven inactivation of P53.
Q92653196MESOTIP: Phase II multicenter randomized trial evaluating the association of PIPAC and systemic chemotherapy vs. systemic chemotherapy alone as 1st-line treatment of malignant peritoneal mesothelioma
Q34182679MET and PI3K/mTOR as a potential combinatorial therapeutic target in malignant pleural mesothelioma
Q46414310MVP and vinorelbine for malignant pleural mesothelioma
Q34616102Macroscopic complete resection: the goal of primary surgery in multimodality therapy for pleural mesothelioma.
Q43274035Maintenance pemetrexed plus best supportive care versus placebo plus best supportive care for non-small-cell lung cancer: a randomised, double-blind, phase 3 study
Q58386415Major Cancer Regressions in Mesothelioma After Treatment with an Anti-Mesothelin Immunotoxin and Immune Suppression
Q39470931Malignant Mesothelioma Effusions Are Infiltrated by CD3+ T Cells Highly Expressing PD-L1 and the PD-L1+ Tumor Cells within These Effusions Are Susceptible to ADCC by the Anti-PD-L1 Antibody Avelumab
Q87849396Malignant Mesothelioma of the Tunica Vaginalis Testis: Outcomes Following Surgical Management Beyond Radical Orchiectomy
Q39366003Malignant Mesothelioma: Time to Translate?
Q35623638Malignant Pleural Mesothelioma Outcomes in the Era of Combined Platinum and Folate Antimetabolite Chemotherapy.
Q89622483Malignant Pleural Mesothelioma: State-of-the-Art on Current Therapies and Promises for the Future
Q41891283Malignant intraperitoneal mesothelioma-Başkent University experience
Q80961479Malignant mesothelioma
Q21202901Malignant mesothelioma
Q37261327Malignant mesothelioma after household exposure to asbestos
Q37386569Malignant mesothelioma of the greater omentum mimicking omental infarction: a case report
Q41987896Malignant mesothelioma of the pericardium: a report of two different presentations
Q27311380Malignant mesothelioma of the pleura with desmoplastic histology: a case series and literature review.
Q89924108Malignant mesothelioma of the tunica vaginalis testis: a rare case and review of literature
Q47098675Malignant mesothelioma: Canadian perspective and research directions
Q37209613Malignant mesothelioma: current status and perspective in Japan and the world
Q36252181Malignant mesothelioma: current status of histopathologic diagnosis and molecular profile
Q28390539Malignant mesothelioma: facts, myths, and hypotheses
Q42203306Malignant paratesticular mesothelioma
Q39107162Malignant pericardial mesothelioma : A systematic review of current practice
Q35614129Malignant peritoneal mesothelioma without asbestos exposure: An ovarian cancer imitator
Q41386272Malignant peritoneal mesothelioma. Is there a new treatment?
Q33871582Malignant peritoneal mesothelioma: a review
Q58541846Malignant peritoneal mesothelioma: clinical aspects, and therapeutic perspectives
Q33909330Malignant peritoneal mesothelioma: prognostic factors and oncologic outcome analysis
Q50197656Malignant pleural fluid from mesothelioma has potent biological activities.
Q83412919Malignant pleural mesothelioma
Q83466825Malignant pleural mesothelioma
Q84107270Malignant pleural mesothelioma
Q79332820Malignant pleural mesothelioma in a 14-year-old boy with right aortic arch
Q36766690Malignant pleural mesothelioma in a 17-year old boy: A case report and literature review.
Q51326575Malignant pleural mesothelioma in a patient with systemic sclerosis: the first report.
Q40041012Malignant pleural mesothelioma: A retrospective analysis of clinicopathological and survival data.
Q59274199Malignant pleural mesothelioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
Q36639812Malignant pleural mesothelioma: a comprehensive review
Q34513958Malignant pleural mesothelioma: an update on diagnosis and treatment options
Q37217764Malignant pleural mesothelioma: current and future perspectives
Q36834027Malignant pleural mesothelioma: current concepts in treatment
Q37529848Malignant pleural mesothelioma: current treatments and emerging drugs.
Q46864339Malignant pleural mesothelioma: further options
Q26821919Malignant pleural mesothelioma: incidence, etiology, diagnosis, treatment, and occupational health
Q42362338Malignant pleural mesothelioma: key determinants in tailoring the right treatment for the right patient
Q36728254Malignant pleural mesothelioma: update on treatment options with a focus on novel therapies.
Q37866786Malignant pleural mesothelioma: when is radiation therapy indicated?
Q95360809Management of database: European Society of Thoracic Surgeons mesothelioma database-difficulties in improving quality data for rare tumour
Q31117531Management of malignant pleural mesothelioma - part 3 : Data from the Austrian Mesothelioma Interest Group (AMIG) database
Q38215513Management of malignant pleural mesothelioma-The European experience
Q37277434Management of malignant pleural mesothelioma-part 2: therapeutic approaches : Consensus of the Austrian Mesothelioma Interest Group (AMIG).
Q35834928Management of malignant pleural mesothelioma: a French multicenter retrospective study (GFPC 0802 study).
Q37621554Management of venous thromboembolism and the potential to impact overall survival in patients with cancer
Q36830116Management options for malignant pleural mesothelioma: clinical and cost considerations
Q51996240Measurement of mesothelioma on thoracic CT scans: a comparison of manual and computer-assisted techniques.
Q30437261Measuring quality of life in patients with pleural mesothelioma using a modified version of the Lung Cancer Symptom Scale (LCSS): psychometric properties of the LCSS-Meso
Q39784143Mechanisms of FUS1/TUSC2 deficiency in mesothelioma and its tumorigenic transcriptional effects.
Q38542421Medical and oncological management of malignant mesothelioma.
Q52672887Medical treatment of malignant pleural mesothelioma relapses.
Q37866663Medical treatment of mesothelioma: anything new?
Q58132938Megakaryocyte Potentiating Factor as a Predictive Biomarker for Therapies Against Malignant Mesothelioma
Q33835620Membrane topological analysis of the proton-coupled folate transporter (PCFT-SLC46A1) by the substituted cysteine accessibility method
Q38971472Membranous nephropathy associated with malignant pleural mesothelioma in an adult patient: A case report
Q34193347Merlin deficiency predicts FAK inhibitor sensitivity: a synthetic lethal relationship
Q61451037MesoTRAP: a feasibility study that includes a pilot clinical trial comparing video-assisted thoracoscopic partial pleurectomy decortication with indwelling pleural catheter in patients with trapped lung due to malignant pleural mesothelioma designed
Q35885161Mesothelial cell proliferation and apoptosis
Q38773361Mesothelin as a target for chimeric antigen receptor-modified T cells as anticancer therapy
Q60934613Mesothelin-targeted second generation CAR-T cells inhibit growth of mesothelin-expressing tumors
Q37201356Mesothelioma and asbestos-related pleural diseases
Q37381458Mesothelioma in the United States: a Surveillance, Epidemiology, and End Results (SEER)-Medicare investigation of treatment patterns and overall survival
Q45182633Mesothelioma research as a social issue
Q38476131Mesothelioma treatment
Q26800042Mesothelioma treatment: Are we on target? A review
Q92898853Mesothelioma: Hippo pathway as a target, lessons from COMMAND
Q35839385Mesothelioma: a review
Q81299291Mesothelioma: time to take stock
Q58122667Metabolic Characterization of Antifolate Responsiveness and Non-responsiveness in Malignant Pleural Mesothelioma Cells
Q36361245Metformin produces growth inhibitory effects in combination with nutlin-3a on malignant mesothelioma through a cross-talk between mTOR and p53 pathways
Q37562633Methotrexate and gemcitabine combination chemotherapy for the treatment of malignant pleural mesothelioma
Q47271729Micro-RNA149 Confers Taxane Resistance to Malignant Mesothelioma Cells via Regulation of P-glycoprotein Expression
Q47170177Minor regression and long-time survival (56 months) in a patient with malignant pleural mesothelioma under Viscum album and Helleborus niger extracts—a case report
Q50585162Minute localized malignant pleural mesothelioma coexisting with multiple adenocarcinomas.
Q34040130Modeling the relationship between progression-free survival and overall survival: the phase II/III trial
Q29248127Modern management of malignant pleural mesothelioma
Q36699347Molecular analysis of the effects of Piroxicam and Cisplatin on mesothelioma cells growth and viability
Q37232301Molecular biology of malignant mesothelioma
Q38012566Molecular pathogenesis of malignant mesothelioma
Q38107102Molecular pathogenesis of malignant mesothelioma
Q79968444Molecular profiling of malignant peritoneal mesothelioma identifies the ubiquitin-proteasome pathway as a therapeutic target in poor prognosis tumors
Q41869395Molecular profiling reveals primary mesothelioma cell lines recapitulate human disease.
Q28482133Molecular resistance fingerprint of pemetrexed and platinum in a long-term survivor of mesothelioma
Q36822118Multicenter phase II trial of neoadjuvant pemetrexed plus cisplatin followed by extrapleural pneumonectomy and radiation for malignant pleural mesothelioma
Q36097706Multicenter, double-blind, placebo-controlled, randomized phase II trial of gemcitabine/cisplatin plus bevacizumab or placebo in patients with malignant mesothelioma
Q43466291Multicentric study on malignant pleural mesothelioma in Turkey: clinicopathologic and survival characteristics of 282 patients.
Q36599666Multimodal therapy of malignant pleural mesothelioma: is the replacement of radical surgery imminent?
Q36889671Mutation analysis of the EGFR gene and downstream signalling pathway in histologic samples of malignant pleural mesothelioma
Q50137415Mutational Profiling of Malignant Mesothelioma Revealed Potential Therapeutic Targets in EGFR and NRAS.
Q88649792NGR-hTNF in combination with best investigator choice in previously treated malignant pleural mesothelioma (NGR015): a randomised, double-blind, placebo-controlled phase 3 trial
Q52564739Nano-selenium and its nanomedicine applications: a critical review.
Q40354488Neoadjuvant chemotherapy and extrapleural pneumonectomy of malignant pleural mesothelioma with or without hemithoracic radiotherapy (SAKK 17/04): a randomised, international, multicentre phase 2 trial
Q35958459Nephrotoxicity of cisplatin combination chemotherapy in thoracic malignancy patients with CKD risk factors
Q52581757New Perspectives on Diagnosis and Therapy of Malignant Pleural Mesothelioma.
Q35042668New and emerging therapeutic options for malignant pleural mesothelioma: review of early clinical trials
Q87296127New directions in the second line treatment of non-small cell lung cancers and in the management of malignant pleural mesotheliomas
Q34101029New histone deacetylase inhibitors improve cisplatin antitumor properties against thoracic cancer cells.
Q52672888New horizons from immunotherapy in malignant pleural mesothelioma.
Q26859274New insights into understanding the mechanisms, pathogenesis, and management of malignant mesotheliomas
Q36157300New therapeutic options for mesothelioma
Q36780582Newer issues in mesothelioma chemotherapy.
Q34998586Newly established ELISA for N-ERC/mesothelin improves diagnostic accuracy in patients with suspected pleural mesothelioma
Q92134619Nintedanib in combination with pemetrexed and cisplatin for chemotherapy-naive patients with advanced malignant pleural mesothelioma (LUME-Meso): a double-blind, randomised, placebo-controlled phase 3 trial
Q91966584Nivo-lution in Mesothelioma
Q89411795Nivolumab Immunotherapy in Malignant Mesothelioma: A Case Report Highlighting a New Opportunity for Exceptional Outcomes
Q99582736Nivolumab in pre-treated malignant pleural mesothelioma: real-world data from the Dutch expanded access program
Q34364821Nonamplified FGFR1 is a growth driver in malignant pleural mesothelioma
Q40271615Nonparametric covariate adjustment in estimating hazard ratios
Q44551180Novel ATP-competitive Akt inhibitor afuresertib suppresses the proliferation of malignant pleural mesothelioma cells.
Q39500865Novel acridine-based agents with topoisomerase II inhibitor activity suppress mesothelioma cell proliferation and induce apoptosis
Q35594038Novel chemotherapeutic and targeted agents in metastatic colorectal cancer: the time has arrived
Q39455555Novel insights into mesothelioma biology and implications for therapy.
Q33890499Novel systemic therapy against malignant pleural mesothelioma
Q37855667Novel targeted therapies and vaccination strategies for mesothelioma
Q52672324Novel therapies for malignant pleural mesothelioma.
Q35129535Novel therapies in phase II and III trials for malignant pleural mesothelioma.
Q40051845Oncolytic Viral Therapy for Mesothelioma
Q33402865Open-label, single-arm phase II study of pemetrexed in the treatment of patients with recurrent or metastatic nasopharyngeal carcinoma who have had prior platinum-based chemotherapy
Q38662242Optimal Therapy of Advanced Stage Mesothelioma
Q50484415Optimal gross tumor volume definition in lung-sparing intensity modulated radiotherapy for pleural mesothelioma: an in silico study.
Q36905239Optimising survival in malignant mesothelioma
Q33710475Optimizing Collection of Adverse Event Data in Cancer Clinical Trials Supporting Supplemental Indications
Q26747641Orotate phosphoribosyltransferase is overexpressed in malignant pleural mesothelioma: Dramatically responds one case in high OPRT expression
Q38826424Orthotopic Implantation and Peripheral Immune Cell Monitoring in the II-45 Syngeneic Rat Mesothelioma Model
Q50048236Outcomes of the Multimodal Treatment of Malignant Pleural Mesiothelioma: The Role of Surgery
Q39643717Overexpression of SOCS3 exhibits preclinical antitumor activity against malignant pleural mesothelioma
Q34360248Overview of the biochemical and genetic processes in malignant mesothelioma.
Q47654312PD-L1 expression associated with worse survival outcome in malignant pleural mesothelioma.
Q82257520PET-guided dose escalation tomotherapy in malignant pleural mesothelioma
Q37252398PI3 Kinase Pathway and MET Inhibition is Efficacious in Malignant Pleural Mesothelioma
Q38398970PTEN protein expression in malignant pleural mesothelioma
Q64085851Pain management in patients with malignant mesothelioma: challenges and solutions
Q26768306Palliative cytoreductive surgery and hyperthermic intraperitoneal chemoperfusion: current clinical practice or misnomer?
Q39377749Patients with peritoneal mesothelioma lack epidermal growth factor receptor tyrosine kinase mutations that would make them sensitive to tyrosine kinase inhibitors
Q45327540Patterns of care for malignant pleural mesothelioma patients compensated by the Dust Diseases Board in New South Wales, Australia
Q41697761Patterns of failure, toxicity, and survival after extrapleural pneumonectomy and hemithoracic intensity-modulated radiation therapy for malignant pleural mesothelioma
Q26750670Pemetrexed Maintenance Therapy Following Bevacizumab-Containing First-Line Chemotherapy in Advanced Malignant Pleural Mesothelioma: A Case Report and Literatures Review
Q40168311Pemetrexed acts as an antimyeloma agent by provoking cell cycle blockade and apoptosis.
Q50168144Pemetrexed alone or in combination with cisplatin in previously treated malignant pleural mesothelioma: outcomes from a phase IIIB expanded access program.
Q33732386Pemetrexed alters folate phenotype and inflammatory profile in EA.hy 926 cells grown under low-folate conditions
Q87591998Pemetrexed ameliorates experimental arthritis in rats
Q34091240Pemetrexed and cisplatin for the treatment of advanced, persistent, or recurrent carcinoma of the cervix: a limited access phase II trial of the gynecologic oncology group.
Q37388593Pemetrexed as first-line therapy for non-squamous non-small cell lung cancer.
Q48620677Pemetrexed as second-line chemotherapy for castration-resistant prostate cancer after docetaxel failure: results from a phase II study
Q28081243Pemetrexed clinical studies in performance status 2 patients with non-small cell lung cancer (Review)
Q36166142Pemetrexed disodium
Q80890800Pemetrexed disodium
Q24243222Pemetrexed disodium in combination with cisplatin versus other cytotoxic agents or supportive care for the treatment of malignant pleural mesothelioma
Q34253505Pemetrexed disodium in ovarian cancer treatment
Q38251598Pemetrexed for ovarian cancer: a systematic review of the published literature and a consecutive series of patients treated in a nonclinical trial setting
Q38107552Pemetrexed for the treatment of non-small cell lung cancer.
Q35003631Pemetrexed for the treatment of non-small-cell lung cancer
Q34113895Pemetrexed in advanced non-small-cell lung cancer
Q44523490Pemetrexed in combination with cisplatin versus cisplatin monotherapy in East Asian patients with recurrent or metastatic head and neck cancer: Results of an exploratory subgroup analysis of a phase III trial
Q58828317Pemetrexed in combination with cisplatin versus cisplatin monotherapy in patients with recurrent or metastatic head and neck cancer
Q37818301Pemetrexed in heavily pretreated non-small-cell lung cancer patients: case report and review of the literature
Q45799446Pemetrexed in patients with refractory soft tissue sarcoma: a non-comparative multicenter phase II study of the German Sarcoma Group AIO-STS 005.
Q36817105Pemetrexed in small-cell lung cancer: background and review of the ongoing GALES pivotal trial
Q34516941Pemetrexed in thoracic cancer
Q88200768Pemetrexed induced acute kidney injury in patients with non-small cell lung cancer: reversible and chronic renal damage
Q33379936Pemetrexed plus carboplatin in elderly patients with malignant pleural mesothelioma: combined analysis of two phase II trials.
Q34401277Pemetrexed therapy for malignant pleural mesothelioma
Q34517532Pemetrexed, a novel antifolate therapeutic alternative for cancer chemotherapy
Q47134185Pemetrexed-Induced Interstitial Pneumonitis: A Case Study and Literature Review
Q36118385Pemetrexed-cisplatin combination in mesothelioma
Q39297327Pemetrexed-induced acute kidney failure following irreversible renal damage: two case reports and literature review
Q61811213Pemetrexed-loaded nanoparticles targeted to malignant pleural mesothelioma cells: an in vitro study
Q38415044Performance of biomarkers SMRP, CA125, and CYFRA 21-1 as potential tumor markers for malignant mesothelioma and lung cancer in a cohort of workers formerly exposed to asbestos.
Q37492386Pericardial Effusion due to Primary Malignant Pericardial Mesothelioma: A Common Finding but an Uncommon Cause
Q55107856Perioperative chemotherapy with pemetrexed and cisplatin for pulmonary large-cell neuroendocrine carcinoma: a case report and literature review.
Q36790055Perspective on malignant pleural mesothelioma diagnosis and treatment
Q50648690Pharmacogenetics of pemetrexed combination therapy in lung cancer: pathway analysis reveals novel toxicity associations.
Q36600202Pharmacokinetic Properties of Anticancer Agents for the Treatment of Central Nervous System Tumors: Update of the Literature
Q37877715Pharmacokinetic evaluation of pemetrexed
Q38733577Phase 1 Dose-Escalation Study of Pegylated Arginine Deiminase, Cisplatin, and Pemetrexed in Patients With Argininosuccinate Synthetase 1-Deficient Thoracic Cancers
Q64890042Phase 1 study of the antimesothelin immunotoxin SS1P in combination with pemetrexed and cisplatin for front-line therapy of pleural mesothelioma and correlation of tumor response with serum mesothelin, megakaryocyte potentiating factor, and cancer a
Q40951154Phase I Study of Concomitant Pemetrexed and Cisplatin Plus External Beam Radiation Therapy in Patients with Locally Advanced or Metastatic Esophageal or Gastroesophageal Junction Carcinomas
Q33442594Phase I Trial of Cediranib in combination with cisplatin and pemetrexed in chemo naive patients with unresectable malignant pleural mesothelioma (SWOG S0905).
Q46781636Phase I study of a 3-drug regimen of gemcitabine/cisplatin/pemetrexed in patients with metastatic transitional cell carcinoma of the urothelium
Q37367634Phase I trial of cisplatin, pemetrexed, and imatinib mesylate in chemonaive patients with unresectable malignant pleural mesothelioma
Q35931270Phase I trial of intraperitoneal pemetrexed, cisplatin, and paclitaxel in optimally debulked ovarian cancer
Q35432484Phase I trial of pemetrexed in combination with cetuximab and concurrent radiotherapy in patients with head and neck cancer
Q44405249Phase II Study of Pemetrexed With and Without Folic Acid and Vitamin B12 as Front-Line Therapy in Malignant Pleural Mesothelioma
Q92450953Phase II Trial of Cediranib in Combination With Cisplatin and Pemetrexed in Chemotherapy-Naïve Patients With Unresectable Malignant Pleural Mesothelioma (SWOG S0905)
Q34614847Phase II clinical trial of amatuximab, a chimeric antimesothelin antibody with pemetrexed and cisplatin in advanced unresectable pleural mesothelioma
Q37212223Phase II evaluation of pemetrexed in the treatment of recurrent or persistent platinum-resistant ovarian or primary peritoneal carcinoma: a study of the Gynecologic Oncology Group
Q35686880Phase II study of belinostat (PXD101), a histone deacetylase inhibitor, for second line therapy of advanced malignant pleural mesothelioma
Q36337646Phase II study of cediranib in patients with malignant pleural mesothelioma: SWOG S0509
Q35840886Phase II study of dasatinib in patients with previously treated malignant mesothelioma (cancer and leukemia group B 30601): a brief report
Q40814215Phase II study of oral vitamin B12 supplementation as an alternative to intramuscular injection for patients with non-small cell lung cancer undergoing pemetrexed therapy
Q37081896Phase II study of pemetrexed and carboplatin plus bevacizumab as first-line therapy in malignant pleural mesothelioma
Q33369094Phase II study of pemetrexed in combination with carboplatin in the first-line treatment of advanced nonsmall cell lung cancer
Q35677288Phase II study of pemetrexed in combination with cisplatin in patients with advanced urothelial cancer: the PECULIAR study (KCSG 10-17).
Q37126012Phase II study of pemetrexed in patients with advanced neuroendocrine tumors
Q34549793Phase II trial of neoadjuvant pemetrexed plus cisplatin followed by surgery and radiation in the treatment of pleural mesothelioma
Q34877504Phase II trial of pemetrexed and bevacizumab in patients with recurrent or metastatic head and neck cancer.
Q53584625Phase II trial of pemetrexed as second-line therapy in patients with metastatic urothelial carcinoma.
Q37439034Phase II trial of pemetrexed plus gemcitabine in patients with locally advanced and metastatic nonclear cell renal cell carcinoma
Q34747440Photodynamic therapy for lung cancer and malignant pleural mesothelioma.
Q39779237Photodynamic therapy for malignant pleural mesothelioma: the future of treatment?
Q55605572Pirfenidone decreases mesothelioma cell proliferation and migration via inhibition of ERK and AKT and regulates mesothelioma tumor microenvironment in vivo.
Q40166240Pleural Diseases: Saline Irrigation in Pleural Infection, Epidemiology of Pneumothorax, and Bevacizumab in Mesothelioma
Q37777879Pleural Malignancies
Q42582696Pleural effusion: what lies underneath?
Q35168185Pleural mesothelioma instigates tumor-associated fibroblasts to promote progression via a malignant cytokine network
Q35903121Pleural mesothelioma: little evidence, still time to do trials
Q41429967Polyanionic Biopolymers for the Delivery of Pt(II) Cationic Antiproliferative Complexes
Q33831942Polymorphisms in folate pathway and pemetrexed treatment outcome in patients with malignant pleural mesothelioma
Q38905403Population pharmacokinetics and exposure-response relationship of amatuximab, an anti-mesothelin monoclonal antibody, in patients with malignant pleural mesothelioma and its application in dose selection
Q37001982Positive response of a primary malignant pericardial mesothelioma to pemetrexed plus cisplatin followed by pemetrexed maintenance chemotherapy: A case report
Q51444618Possible new therapeutic agents for malignant pleural mesothelioma: anti-CD26 monoclonal antibody and naftopidil.
Q36287976Post-chemotherapy T-cell recovery is a marker of improved survival in patients with advanced thoracic malignancies
Q39260316Post-recurrence chemotherapy for mesothelioma patients undergoing extrapleural pneumonectomy
Q54949713Potential role of pemetrexed in metastatic breast cancer patients pre-treated with anthracycline or taxane.
Q39463417Preclinical emergence of vandetanib as a potent antitumour agent in mesothelioma: molecular mechanisms underlying its synergistic interaction with pemetrexed and carboplatin
Q50049398Predictors of trimodality therapy and trends in therapy for malignant pleural mesothelioma
Q89838575Prevalence, etiology and risk factors of anemia in patients with newly diagnosed cancer
Q53129830Primary malignant mesothelioma of the spermatic cord.
Q37406758Primary malignant pericardial mesothelioma with increased serum mesothelin diagnosed by surgical pericardial resection: A case report
Q93338919Product review: avelumab, an anti-PD-L1 antibody
Q38961442Prognostic and predictive aspects of the tumor immune microenvironment and immune checkpoints in malignant pleural mesothelioma
Q33918135Prognostic factors in elderly patients with malignant pleural mesothelioma: results of a multicenter survey
Q43875251Prognostic nutritional index predicts outcomes of malignant pleural mesothelioma
Q41234207Prognostic significance of soluble mesothelin in malignant pleural mesothelioma: a meta-analysis
Q53175010Prognostic value of 18F-FDG standard uptake value by integrated PET/CT in the staging of malignant pleural mesothelioma.
Q89759390Prognostic value of SUVmax on 18F-fluorodeoxyglucose PET/CT scan in patients with malignant pleural mesothelioma
Q39124644Prognostication and monitoring of mesothelioma using biomarkers: a systematic review
Q51501402Progranulin and granulin-like protein as novel VEGF-independent angiogenic factors derived from human mesothelioma cells.
Q52663125Progress in the Management of Malignant Pleural Mesothelioma in 2017.
Q89889132Prolonged Progression-Free Survival in a Patient With Malignant Pleural Mesothelioma Following Korean Herbal Medicine Treatment Alone: A Case Report
Q40223042Propensity matched comparison of extrapleural pneumonectomy and pleurectomy/decortication for mesothelioma patients†.
Q95548086Prophylactic radiotherapy to prevent procedure-tract metastases
Q24170504Proteasome inhibitor MG132 induces apoptosis and inhibits invasion of human malignant pleural mesothelioma cells
Q47096168Proteasome stress sensitizes malignant pleural mesothelioma cells to bortezomib-induced apoptosis
Q42825571Protection of hematopoietic stem cells from pemetrexed toxicity by retroviral gene transfer with a mutant dihydrofolate reductase-mutant thymidylate synthase fusion gene
Q37020881Protein kinase C beta in malignant pleural mesothelioma
Q36526737Protocol for PIT: a phase III trial of prophylactic irradiation of tracts in patients with malignant pleural mesothelioma following invasive chest wall intervention
Q30614413Protocol for the surgical and large bore procedures in malignant pleural mesothelioma and radiotherapy trial (SMART Trial): an RCT evaluating whether prophylactic radiotherapy reduces the incidence of procedure tract metastases.
Q55037897Proton beam therapy for malignant pleural mesothelioma.
Q52560709Putative cancer stem cells may be the key target to inhibit cancer cell repopulation between the intervals of chemoradiation in murine mesothelioma.
Q55082913Quality of life of survivors of malignant pleural mesothelioma in Japan: a cross sectional study.
Q55318621Quantitative Clinical Staging for Patients With Malignant Pleural Mesothelioma.
Q45020726Quantitative analyses at baseline and interim PET evaluation for response assessment and outcome definition in patients with malignant pleural mesothelioma.
Q47197708Radical multimodality therapy for malignant pleural mesothelioma.
Q39438176Radio-immunotherapy and chemo-immunotherapy as a novel treatment paradigm in malignant pleural mesothelioma
Q37392453Radiotherapy applications of patients with malignant mesothelioma: A single center experience
Q24245556Radiotherapy for malignant pleural mesothelioma
Q37945636Raltitrexed in mesothelioma
Q90659960Randomised placebo-controlled cross-over study examining the role of anamorelin in mesothelioma (The ANTHEM study): rationale and protocol
Q52562413Randomized phase 2 study of gemcitabine and cisplatin with or without vitamin supplementation in patients with advanced esophagogastric cancer.
Q33404434Randomized phase 2 trial on refinement of early-stage NSCLC adjuvant chemotherapy with cisplatin and pemetrexed versus cisplatin and vinorelbine: the TREAT study
Q36425940Ranpirnase--an antitumour ribonuclease: its potential role in malignant mesothelioma
Q34142500Ratio of intratumoral macrophage phenotypes is a prognostic factor in epithelioid malignant pleural mesothelioma
Q34402081Re-challenge with pemetrexed in advanced mesothelioma: a multi-institutional experience.
Q44647820Re: a multicenter phase II study of gemcitabine and oxaliplatin for malignant pleural mesothelioma
Q28392665Reactive oxygen species a double-edged sword for mesothelioma
Q49703405Real-life feasibility of home-based pulmonary rehabilitation in chemotherapy-treated patients with thoracic cancers: a pilot study.
Q34265773Rechallenge with pemetrexed-based chemotherapy improves the survival of patients with advanced non-squamous non-small-cell lung cancer
Q36779095Reduced folate and serum vitamin metabolites in patients with rectal carcinoma: an open-label feasibility study of pemetrexed with folic acid and vitamin B12 supplementation
Q91949964Relations between approved platinum drugs and non-coding RNAs in mesothelioma
Q30240233Relevance of randomised controlled trials in oncology.
Q35175013Replication-competent retrovirus vector-mediated prodrug activator gene therapy in experimental models of human malignant mesothelioma
Q35567272Resistance to antifolates
Q42585963Response to comment on 'Existing prognostic models, but not neutrophil-to-lymphocyte ratio, are prognostic in malignant mesothelioma'.
Q39073648Restoring expression of miR-16: a novel approach to therapy for malignant pleural mesothelioma.
Q43132169Retreatment of recurrent malignant pleural mesothelioma with cisplatin and pemetrexed
Q58128741Review of nintedanib plus pemetrexed/cisplatin in patients with malignant pleural mesothelioma: phase II results from the randomized, placebo-controlled LUME-Meso trial
Q36822893Review of pemetrexed in combination with cisplatin for the treatment of malignant pleural mesothelioma
Q37873380Review on clinical trials of targeted treatments in malignant mesothelioma
Q28066950Role of Akt signaling in resistance to DNA-targeted therapy
Q38190418Role of microRNAs in malignant mesothelioma.
Q39043688Role of postoperative radiotherapy in the management of malignant pleural mesothelioma : A propensity score matching of the SEER database
Q89753976Role of thoracoscopy, mediastinoscopy and laparoscopy in the diagnosis and staging of malignant pleural mesothelioma
Q39991261SIRT1 at the crossroads of AKT1 and ERβ in malignant pleural mesothelioma cells
Q39359156SOCS-1 gene delivery cooperates with cisplatin plus pemetrexed to exhibit preclinical antitumor activity against malignant pleural mesothelioma
Q39350876SU6668, a multiple tyrosine kinase inhibitor, inhibits progression of human malignant pleural mesothelioma in an orthotopic model
Q52802449SYSTEMS-2: A randomised phase II study of radiotherapy dose escalation for pain control in malignant pleural mesothelioma.
Q38786021Safety profiles of first-line therapies for metastatic non-squamous non-small-cell lung cancer
Q37478901Sarcomatoid Type Primary Pericardial Mesothelioma with a Long-term Survival after the Onset of Cardiac Tamponade
Q89390949Scientific Advances and New Frontiers in Mesothelioma Therapeutics
Q38365768Searching for targets for the systemic therapy of mesothelioma.
Q33582141Second generation sequencing of the mesothelioma tumor genome
Q50665635Second-line gemcitabine-based chemotherapy regimens improve overall 3-year survival rate in patients with malignant pleural mesothelioma: a multicenter retrospective study.
Q42864235Second-line therapy in patients with malignant pleural mesothelioma. A French retrospective study (2005-2006)
Q37937879Second-line treatment options in advanced non-small cell lung cancer
Q33434963Seminiferous epithelium damage after short period of busulphan treatment in adult rats and vitamin B12 efficacy in the recovery of spermatogonial germ cells.
Q26828610Serine, glycine and one-carbon units: cancer metabolism in full circle
Q34687224Serum HMGB1 as a prognostic marker for malignant pleural mesothelioma
Q36105547Serum Survivin Levels and Outcome of Chemotherapy in Patients with Malignant Mesothelioma
Q54678404Serum biomarkers in patients with mesothelioma and pleural plaques and healthy subjects exposed to naturally occurring asbestos.
Q26860736Serum mesothelin for diagnosing malignant pleural mesothelioma: an individual patient data meta-analysis
Q83017468Severe rhabdomyolysis associated with pemetrexed-based chemotherapy
Q48315996Sialic acid-binding lectin from bullfrog eggs inhibits human malignant mesothelioma cell growth in vitro and in vivo.
Q59796596Simultaneous presence of lung adenocarcinoma and malignant pleural mesothelioma: A case report
Q34543815Single agent and combination studies of pralatrexate and molecular correlates of sensitivity
Q46170046Single-dose dexamethasone for the prevention of pemetrexed associated cutaneous adverse reactions
Q37582256Small bowel metastasis from pancreatic cancer in a long-term survival patient with synchronous advanced malignant pleural mesothelioma: A case report and literature review
Q34096881Soluble mesothelin related peptides (SMRP) and osteopontin as protein biomarkers for malignant mesothelioma: analytical validation of ELISA based assays and characterization at mRNA and protein levels
Q36858876Speeding up the evaluation of new agents in cancer
Q52990918Spontaneous Regression of Malignant Pleural Mesothelioma in a Patient with New-Onset Inflammatory Arthropathy.
Q33563281Spotlight on bevacizumab and its potential in the treatment of malignant pleural mesothelioma: the evidence to date
Q80218915Squamous cell carcinoma of the lung compared with other histotypes shows higher messenger RNA and protein levels for thymidylate synthase
Q46807402Standard therapy for the treatment of malignant pleural mesothelioma
Q99594750Standards of care in mesothelioma treatment
Q38204673Standing the test of time: targeting thymidylate biosynthesis in cancer therapy
Q34501203Starvation-induced activation of ATM/Chk2/p53 signaling sensitizes cancer cells to cisplatin
Q44080402Stratification of malignant pleural mesothelioma prognosis using recursive partitioning analysis
Q44282851Sunitinib combined with pemetrexed and cisplatin: results of a phase I dose-escalation and pharmacokinetic study in patients with advanced solid malignancies, with an expanded cohort in non-small cell lung cancer and mesothelioma
Q36451785Suppression of activin A signals inhibits growth of malignant pleural mesothelioma cells
Q37762833Surgery for malignant pleural mesothelioma
Q37552639Surgery in the treatment of malignant pleural mesothelioma: recruitment into trials should be the default position
Q37398672Surgical biology for the clinician: peritoneal mesothelioma: current understanding and management.
Q36594263Surgical controversies in mesothelioma: MesoVATS addresses the role of surgical debulking
Q38195607Surgical management of malignant pleural mesothelioma: impact of surgery on survival and quality of life-relation to chemotherapy, radiotherapy, and alternative therapies.
Q51716124Surgical resection of mesothelioma: an evidence-free practice.
Q30401535Surgical treatment of malignant pleural mesothelioma
Q38163913Surgical treatment of peritoneal carcinomatosis: current treatment modalities
Q53184110Survival and relapse pattern after trimodality therapy for malignant pleural mesothelioma.
Q40165996Survival improvement in thoracic cancer: progress from the last decade and beyond
Q38607308Survival in Good Performance Malignant Pleural Mesothelioma Patients; Prognostic Factors and Predictors of Response
Q50286398Survival prediction in mesothelioma using a scalable Lasso regression model: instructions for use and initial performance using clinical predictors.
Q92958905Synergistic Enhancement of Cellular Uptake With CD44-Expressing Malignant Pleural Mesothelioma by Combining Cationic Liposome and Hyaluronic Acid-Lipid Conjugate
Q42131424Synergistic anti-tumor effect of bullfrog sialic acid-binding lectin and pemetrexed in malignant mesothelioma
Q38765125Synergistic anti-tumor efficacy of immunogenic adenovirus ONCOS-102 (Ad5/3-D24-GM-CSF) and standard of care chemotherapy in preclinical mesothelioma model
Q49387613Synergistic effect of targeting dishevelled-3 and the epidermal growth factor receptor-tyrosine kinase inhibitor on mesothelioma cells in vitro
Q41279899Synergistic targeting of malignant pleural mesothelioma cells by MDM2 inhibitors and TRAIL agonists
Q34622818Systematic review of response rates of sarcomatoid malignant pleural mesotheliomas in clinical trials
Q38131498Systematic review of trimodality therapy for patients with malignant pleural mesothelioma
Q93380858Systemic Therapy Use and Outcomes After Relapse from Preoperative Radiation and Extrapleural Pneumonectomy for Malignant Pleural Mesothelioma
Q33834736Systemic but not topical TRAIL-expressing mesenchymal stem cells reduce tumour growth in malignant mesothelioma
Q38586323Systemic therapy options for malignant pleural mesothelioma beyond first-line therapy: a systematic review.
Q37260408Systemic treatments for mesothelioma: standard and novel
Q23910293TRAIL and proteasome inhibitors combination induces a robust apoptosis in human malignant pleural mesothelioma cells through Mcl-1 and Akt protein cleavages
Q85246015TS expression predicts postoperative recurrence in adenocarcinoma of the lung
Q43605106TS mRNA levels can predict pemetrexed and raltitrexed sensitivity in colorectal cancer
Q37620658TXNL1-XRCC1 pathway regulates cisplatin-induced cell death and contributes to resistance in human gastric cancer
Q52672891Target therapy: new drugs or new combinations of drugs in malignant pleural mesothelioma.
Q33322420Targeted drug delivery to mesothelioma cells using functionally selected internalizing human single-chain antibodies
Q55247848Targeting Tie-2/angiopoietin axis in experimental mesothelioma confers differential responses and raises predictive implications.
Q39438189Targeting eukaryotic protein translation in mesothelioma
Q47107902Targeting mesothelin receptors with drug-loaded bacterial nanocells suppresses human mesothelioma tumour growth in mouse xenograft models
Q47133472Targeting microRNA to improve diagnostic and therapeutic approaches for malignant mesothelioma
Q52642770Targeting the Hippo Pathway Is a New Potential Therapeutic Modality for Malignant Mesothelioma.
Q38815319Targeting the vasculature: anti-angiogenic agents for malignant mesothelioma
Q47393402Temporal and spatial heterogeneity of programmed cell death 1-Ligand 1 expression in malignant mesothelioma
Q43800002Thalidomide versus active supportive care for maintenance in patients with malignant mesothelioma after first-line chemotherapy (NVALT 5): an open-label, multicentre, randomised phase 3 study
Q47133389The "don't eat me" signal CD47 is a novel diagnostic biomarker and potential therapeutic target for diffuse malignant mesothelioma
Q88516121The Antemortem Diagnosis of Primary Malignant Pericardial Mesothelioma: A Multidisciplinary Evaluation
Q38935092The MesoVATS trial: is there a future for video-assisted thoracoscopic surgery partial pleurectomy?
Q36753856The N-ERC index is a novel monitoring and prognostic marker for advanced malignant pleural mesothelioma
Q89502927The Role of Neoadjuvant Chemotherapy in Patients with Resectable Malignant Pleural Mesothelioma - An Institutional and National Analysis
Q36101238The Role of Regulatory T Cells in Mesothelioma.
Q35274923The South West Area Mesothelioma and Pemetrexed trial: a multicentre prospective observational study evaluating novel markers of chemotherapy response and prognostication
Q37183495The antifolates
Q41376845The challenge of prognostic markers in pleural mesothelioma
Q34464981The cost of treating advanced non-small cell lung cancer: estimates from the chinese experience.
Q38125259The current state of pemetrexed in ovarian cancer
Q35274986The effect of chemotherapy on health-related quality of life in mesothelioma: results from the SWAMP trial.
Q35686558The effectiveness and safety of platinum-based pemetrexed and platinum-based gemcitabine treatment in patients with malignant pleural mesothelioma
Q42019544The evolution of multimodality therapy for malignant pleural mesothelioma
Q28067111The evolution of the diminishing role of extrapleural pneumonectomy in the surgical management of malignant pleural mesothelioma
Q36671963The expression of Axl receptor tyrosine kinase influences the tumour phenotype and clinical outcome of patients with malignant pleural mesothelioma
Q38148036The function, mechanisms, and role of the genes PTEN and TP53 and the effects of asbestos in the development of malignant mesothelioma: a review focused on the genes' molecular mechanisms
Q92134624The future of mesothelioma treatment: time to shift gear
Q51937381The high post-test probability of a cytological examination renders further investigations to establish a diagnosis of epithelial malignant pleural mesothelioma redundant.
Q55339037The management of malignant pleural mesothelioma in the USA 2004-13-a decade of lost opportunity?
Q42995477The need for randomized trials in mesothelioma: let's walk the talk
Q33890518The promise of emerging developments and concepts in mesothelioma
Q33658554The role of folate receptor alpha (FRalpha) in the response of malignant pleural mesothelioma to pemetrexed-containing chemotherapy
Q35200628The role of interleukin-6 in malignant mesothelioma
Q55432585The role of pemetrexed in recurrent epithelial ovarian cancer: A scoping review.
Q45952963The role of perioperative systemic chemotherapy in diffuse malignant peritoneal mesothelioma patients treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.
Q39631400The therapeutic efficacy of S-1 against orthotopically implanted human pleural mesothelioma cells in severe combined immunodeficient mice
Q35051339Therapeutic activity of glycoengineered anti-GM2 antibodies against malignant pleural mesothelioma.
Q39290976Therapeutic antitumor efficacy of anti-epidermal growth factor receptor antibody, cetuximab, against malignant pleural mesothelioma
Q64101494Therapeutic efficacy evaluation of radioimmunotherapy with Y-labeled anti-podoplanin antibody NZ-12 for mesothelioma
Q44537561Therapeutic strategies for well-differentiated papillary mesothelioma of the peritoneum.
Q46601914Therapeutic targeting of multiple signaling pathways in malignant pleural mesothelioma
Q51709284Therapy response in malignant pleural mesothelioma-role of MRI using RECIST, modified RECIST and volumetric approaches in comparison with CT.
Q53641990Third-line chemotherapy with carboplatin, gemcitabine and liposomised doxorubicin for malignant pleural mesothelioma.
Q53657513Thromboembolic Events in Malignant Pleural Mesothelioma.
Q36696282Thymidylate synthase and folyl-polyglutamate synthase are not clinically useful markers of response to pemetrexed in patients with malignant pleural mesothelioma
Q37929783Thymidylate synthase inhibitors for non-small cell lung cancer
Q92067214Timing of folic acid/vitamin B12 supplementation and hematologic toxicity during first-line treatment of patients with nonsquamous non-small cell lung cancer using pemetrexed-based chemotherapy: The PEMVITASTART randomized trial
Q37745215Tissue transglutaminase (TG2) enables survival of human malignant pleural mesothelioma cells in hypoxia.
Q57818345Transglutaminase is a mesothelioma cancer stem cell survival protein that is required for tumor formation
Q37806309Translational advances in pleural malignancies
Q42563176Translational immunotherapeutics: chemoimmunotherapy for malignant pleural mesothelioma
Q37734455Translational therapies for malignant pleural mesothelioma.
Q44681845Treatment and survival analyses of malignant mesothelioma in Japan
Q40341641Treatment failure after extrapleural pneumonectomy for malignant pleural mesothelioma.
Q61583558Treatment for non small cell lung cancer, small cell lung cancer and pleural mesothelioma within the EORTC Lung Cancer Group: past, present and future
Q36967160Treatment of acute lymphoblastic leukaemia : a new era.
Q55078906Treatment of malignant pleural mesothelioma: lessons learned and quo vadis?
Q39476907Treatment of mesothelioma with gene-modified PA1STK cells and ganciclovir: a phase I study
Q56892124Tremelimumab combined with durvalumab in patients with mesothelioma (NIBIT-MESO-1): an open-label, non-randomised, phase 2 study
Q44807139Tremelimumab for patients with chemotherapy-resistant advanced malignant mesothelioma: an open-label, single-arm, phase 2 trial
Q38631254Tremelimumab for the treatment of malignant mesothelioma
Q28209997Trial on refinement of early stage non-small cell lung cancer. Adjuvant chemotherapy with pemetrexed and cisplatin versus vinorelbine and cisplatin: the TREAT protocol
Q46988434Triplet chemotherapy for malignant pericardial mesothelioma: a case report
Q35591904Triptolide and its prodrug minnelide suppress Hsp70 and inhibit in vivo growth in a xenograft model of mesothelioma.
Q37597672Tsc1-Tp53 loss induces mesothelioma in mice, and evidence for this mechanism in human mesothelioma
Q35880415Tumoral CD10 expression correlates with aggressive histology and prognosis in patients with malignant pleural mesothelioma.
Q92460078Tumour Treating Fields for mesothelioma
Q92460083Tumour Treating Fields for mesothelioma
Q90808642Tumour Treating Fields in combination with pemetrexed and cisplatin or carboplatin as first-line treatment for unresectable malignant pleural mesothelioma (STELLAR): a multicentre, single-arm phase 2 trial
Q101216977Tumour treating fields therapy for glioblastoma: current advances and future directions
Q36755500Update on the molecular biology of malignant mesothelioma
Q41220761Updated patterns of failure after multimodality therapy for malignant pleural mesothelioma
Q53193985Upregulated p53 expression activates apoptotic pathways in wild-type p53-bearing mesothelioma and enhances cytotoxicity of cisplatin and pemetrexed.
Q45226201Use of cancer therapy at the end of life in patients with malignant pleural mesothelioma.
Q36370311Utilisation of a thoracic oncology database to capture radiological and pathological images for evaluation of response to chemotherapy in patients with malignant pleural mesothelioma
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Q64100362When RON MET TAM in Mesothelioma: All Druggable for One, and One Drug for All?
Q36946792Whole exome and targeted deep sequencing identify genome-wide allelic loss and frequent SETDB1 mutations in malignant pleural mesotheliomas.
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Q41706958Workshop on challenges, insights, and future directions for mouse and humanized models in cancer immunology and immunotherapy: a report from the associated programs of the 2016 annual meeting for the Society for Immunotherapy of cancer.
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Q55444837[A randomized, controlled, multicenter clinical trial comparing pemetrexed/cisplatin and gemcitabine/cisplatin as first-line treatment for advanced nonsquamous non-small cell lung cancer].
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