The dependence of viral RNA replication on co-opted host factors

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The dependence of viral RNA replication on co-opted host factors is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1034895595
P356DOI10.1038/NRMICRO2692
P932PMC publication ID7097227
P698PubMed publication ID22183253
P5875ResearchGate publication ID51901552

P2093author name stringJudit Pogany
Peter D Nagy
P2860cites workHepatitis C virus RNA polymerase and NS5A complex with a SNARE-like proteinQ22010735
An RNA-binding protein, hnRNP A1, and a scaffold protein, septin 6, facilitate hepatitis C virus replicationQ24293290
Identification of FBL2 as a geranylgeranylated cellular protein required for hepatitis C virus RNA replicationQ24302046
Hepatitis C virus RNA replication is regulated by FKBP8 and Hsp90Q24306116
Cyclophilin B is a functional regulator of hepatitis C virus RNA polymeraseQ24306483
Hepatitis C virus infection protein networkQ24311906
Cellular cofactors affecting hepatitis C virus infection and replicationQ24317564
Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartmentQ24337128
Cell proteins TIA-1 and TIAR interact with the 3' stem-loop of the West Nile virus complementary minus-strand RNA and facilitate virus replicationQ24538975
Distinct poly(rC) binding protein KH domain determinants for poliovirus translation initiation and viral RNA replicationQ24539023
5' cloverleaf in poliovirus RNA is a cis-acting replication element required for negative-strand synthesisQ24545690
Interactions between viral nonstructural proteins and host protein hVAP-33 mediate the formation of hepatitis C virus RNA replication complex on lipid raftQ24600344
The ESCRT complexes: structure and mechanism of a membrane-trafficking networkQ24683234
SARS-coronavirus replication is supported by a reticulovesicular network of modified endoplasmic reticulumQ27332392
Three-dimensional analysis of a viral RNA replication complex reveals a virus-induced mini-organelleQ27334421
Cellular COPII proteins are involved in production of the vesicles that form the poliovirus replication complex.Q27469873
Quantitative Analysis of the Hepatitis C Virus Replication ComplexQ27472670
Formation of nsP3-Specific Protein Complexes during Sindbis Virus ReplicationQ27473143
Host Factors in Positive-Strand RNA Virus Genome ReplicationQ27477670
Interaction of TIA-1/TIAR with West Nile and dengue virus products in infected cells interferes with stress granule formation and processing body assemblyQ27478442
Translation elongation factor-1 alpha interacts with the 3' stem-loop region of West Nile virus genomic RNAQ27480847
Interaction between the Cellular Protein eEF1A and the 3'-Terminal Stem-Loop of West Nile Virus Genomic RNA Facilitates Viral Minus-Strand RNA SynthesisQ27481473
Seeking Membranes: Positive-Strand RNA Virus Replication ComplexesQ27487147
Heterogeneous nuclear ribonucleoprotein A1 binds to the transcription-regulatory region of mouse hepatitis virus RNA.Q36568378
Involvement of cellular membrane traffic proteins in poliovirus replicationQ36716351
In vitro assembly of the Tomato bushy stunt virus replicase requires the host Heat shock protein 70Q37018802
Membrane Synthesis, Specific Lipid Requirements, and Localized Lipid Composition Changes Associated with a Positive-Strand RNA Virus RNA Replication ProteinQ37060204
Modification of intracellular membrane structures for virus replicationQ37139313
Yeast as a model host to explore plant virus-host interactionsQ37142027
Mitochondrion-enriched anionic phospholipids facilitate flock house virus RNA polymerase membrane associationQ37157148
TOM1, an Arabidopsis gene required for efficient multiplication of a tobamovirus, encodes a putative transmembrane protein.Q37410846
Translation elongation factor 1A is a component of the tombusvirus replicase complex and affects the stability of the p33 replication co-factor.Q37447365
Pathogenesis of flavivirus infections: using and abusing the host cellQ37452139
Coordination of lipid metabolism in membrane biogenesis.Q37540097
Cytoplasmic viral replication complexesQ37773687
Global Genomics and Proteomics Approaches to Identify Host Factors as Targets to Induce Resistance Against Tomato Bushy Stunt VirusQ37801998
The host Pex19p plays a role in peroxisomal localization of tombusvirus replication proteinsQ38288494
Identification of a region of the tobacco mosaic virus 126- and 183-kilodalton replication proteins which binds specifically to the viral 3'-terminal tRNA-like structureQ38352174
Role of cholesterol pathways in norovirus replicationQ38509910
Potential roles for cellular cofactors in hepatitis C virus replication complex formationQ39322241
Interactions of viral protein 3CD and poly(rC) binding protein with the 5' untranslated region of the poliovirus genomeQ39589554
Functional Sindbis virus replicative complexes are formed at the plasma membraneQ39657845
Complete inhibition of tobamovirus multiplication by simultaneous mutations in two homologous host genes.Q39682641
Cholesterol biosynthesis modulation regulates dengue viral replicationQ39856050
Cholesterol manipulation by West Nile virus perturbs the cellular immune responseQ40051201
Polypyrimidine-tract-binding protein is a component of the HCV RNA replication complex and necessary for RNA synthesisQ40280764
Characterization of the hepatitis C virus RNA replication complex associated with lipid raftsQ40543432
Poliovirus RNA replication requires genome circularization through a protein-protein bridgeQ40791248
Comparison of the replication of positive-stranded RNA viruses of plants and animalsQ41191980
Viral RNA replication. With a little help from the hostQ41610017
Functional interaction of heterogeneous nuclear ribonucleoprotein C with poliovirus RNA synthesis initiation complexesQ41865668
Interactions between brome mosaic virus RNAs and cytoplasmic processing bodies.Q42021176
Semliki Forest virus mRNA capping enzyme requires association with anionic membrane phospholipids for activityQ42034834
A temperature sensitive mutant of heat shock protein 70 reveals an essential role during the early steps of tombusvirus replicationQ42188683
Specific binding of tombusvirus replication protein p33 to an internal replication element in the viral RNA is essential for replicationQ42709852
Ubiquitination of tombusvirus p33 replication protein plays a role in virus replication and binding to the host Vps23p ESCRT proteinQ42915972
The influence of cholesterol and lipid metabolism on host cell structure and hepatitis C virus replicationQ42998138
Membrane interaction of segment H1 (NS4B(H1)) from hepatitis C virus non-structural protein 4B.Q43032587
Identification of essential host factors affecting tombusvirus RNA replication based on the yeast Tet promoters Hughes CollectionQ43155068
Proteomics analysis of the tombusvirus replicase: Hsp70 molecular chaperone is associated with the replicase and enhances viral RNA replicationQ43236251
A host Ca2+/Mn2+ ion pump is a factor in the emergence of viral RNA recombinantsQ44008871
Coronaviruses Hijack the LC3-I-positive EDEMosomes, ER-derived vesicles exporting short-lived ERAD regulators, for replicationQ44986570
Intracellular location and translocation of silent and active poliovirus replication complexesQ45275887
Tomato bushy stunt virus co-opts the RNA-binding function of a host metabolic enzyme for viral genomic RNA synthesisQ45396593
Heterogeneous nuclear ribonuclear protein K interacts with Sindbis virus nonstructural proteins and viral subgenomic mRNA.Q45403054
Cytological analysis of Saccharomyces cerevisiae cells supporting cymbidium ringspot virus defective interfering RNA replication.Q45419794
Localization of the tomato bushy stunt virus replication protein p33 reveals a peroxisome-to-endoplasmic reticulum sorting pathwayQ45422568
A positive-strand RNA virus replication complex parallels form and function of retrovirus capsidsQ45733045
Sterol, Structure and Membrane FunctionQ56446248
Exploiting alternative subcellular location for replication: tombusvirus replication switches to the endoplasmic reticulum in the absence of peroxisomesQ79755909
The role of the p33:p33/p92 interaction domain in RNA replication and intracellular localization of p33 and p92 proteins of Cucumber necrosis tombusvirusQ81814264
Cellular protein modification by poliovirus: the two faces of poly(rC)-binding proteinQ35947991
Activation of cellular Arf GTPases by poliovirus protein 3CD correlates with virus replication.Q35948087
Viral RNA replication in association with cellular membranes.Q35989096
Viral and cellular proteins involved in coronavirus replication.Q35989126
Protein transport from the late Golgi to the vacuole in the yeast Saccharomyces cerevisiaeQ36137664
Yeast as a model host to dissect functions of viral and host factors in tombusvirus replicationQ36346850
Endosomal and non-endosomal functions of ESCRT proteinsQ36485186
5' cis Elements Direct Nodavirus RNA1 Recruitment to Mitochondrial Sites of Replication Complex FormationQ27488208
Roles for endocytic trafficking and phosphatidylinositol 4-kinase III alpha in hepatitis C virus replicationQ27488365
Translation and replication of hepatitis C virus genomic RNA depends on ancient cellular proteins that control mRNA fatesQ27488970
Essential Role of Cyclophilin A for Hepatitis C Virus Replication and Virus Production and Possible Link to Polyprotein Cleavage KineticsQ27489037
Role of Oxysterol Binding Protein in Hepatitis C Virus infectionQ27489539
Class III Phosphatidylinositol 4-Kinase Alpha and Beta Are Novel Host Factor Regulators of Hepatitis C Virus ReplicationQ27489697
A genome-wide genetic screen for host factors required for hepatitis C virus propagationQ27489773
A Functional Genomic Screen Identifies Cellular Cofactors of Hepatitis C Virus ReplicationQ27489843
Structure of the Q  replicase, an RNA-dependent RNA polymerase consisting of viral and host proteinsQ27662148
Assembly of Q  viral RNA polymerase with host translational elongation factors EF-Tu and -TsQ27664197
Global analysis of protein expression in yeastQ27860658
Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNAQ27861124
Exploration of essential gene functions via titratable promoter allelesQ27933619
Global mapping of the yeast genetic interaction networkQ27934987
Systematic genetic analysis with ordered arrays of yeast deletion mutantsQ28131618
Receptor downregulation and multivesicular-body sortingQ28131720
Global analysis of protein activities using proteome chipsQ28209011
Viral reorganization of the secretory pathway generates distinct organelles for RNA replicationQ28283814
Identification and characterization of the host protein DNAJC14 as a broadly active flavivirus replication modulatorQ28476726
Composition and three-dimensional architecture of the dengue virus replication and assembly sitesQ29615112
RNA interference screen for human genes associated with West Nile virus infectionQ29616376
Switch from translation to RNA replication in a positive-stranded RNA virusQ29617520
Hepatitis C virus RNA replication is regulated by host geranylgeranylation and fatty acidsQ29620653
Virus factories: associations of cell organelles for viral replication and morphogenesisQ30051798
New insights into an old protein: the functional diversity of mammalian glyceraldehyde-3-phosphate dehydrogenase.Q30322264
Turnip mosaic virus RNA replication complex vesicles are mobile, align with microfilaments, and are each derived from a single viral genomeQ30490590
Sequential recruitment of the endoplasmic reticulum and chloroplasts for plant potyvirus replicationQ30492546
Phosphatidylinositol 3-kinase-, actin-, and microtubule-dependent transport of Semliki Forest Virus replication complexes from the plasma membrane to modified lysosomesQ30495294
Yeast genome-wide screen reveals dissimilar sets of host genes affecting replication of RNA virusesQ30851910
SYNCRIP, a member of the heterogeneous nuclear ribonucleoprotein family, is involved in mouse hepatitis virus RNA synthesisQ31127282
Genome-wide screen identifies host genes affecting viral RNA recombinationQ33219824
Screening of the yeast yTHC collection identifies essential host factors affecting tombusvirus RNA recombinationQ33231719
Topology of double-membraned vesicles and the opportunity for non-lytic release of cytoplasmQ33252095
COPI activity coupled with fatty acid biosynthesis is required for viral replicationQ33260346
Identification of host genes involved in hepatitis C virus replication by small interfering RNA technologyQ33285375
Identification of human kinases involved in hepatitis C virus replication by small interference RNA library screening.Q33303326
A key role for heat shock protein 70 in the localization and insertion of tombusvirus replication proteins to intracellular membranesQ33400948
Identification of a lipid kinase as a host factor involved in hepatitis C virus RNA replicationQ33420226
Discovery of insect and human dengue virus host factorsQ33435283
A unique role for the host ESCRT proteins in replication of Tomato bushy stunt virusQ33521256
Complementary transcriptomic, lipidomic, and targeted functional genetic analyses in cultured Drosophila cells highlight the role of glycerophospholipid metabolism in Flock House virus RNA replicationQ33541729
A targeted analysis of cellular chaperones reveals contrasting roles for heat shock protein 70 in flock house virus RNA replicationQ33558724
An RNA element at the 5'-end of the poliovirus genome functions as a general promoter for RNA synthesisQ33598563
Inhibition of sterol biosynthesis reduces tombusvirus replication in yeast and plantsQ33648937
Translation Elongation Factor 1A Facilitates the Assembly of the Tombusvirus Replicase and Stimulates Minus-Strand SynthesisQ33747578
Host protein interactions with the 3' end of bovine coronavirus RNA and the requirement of the poly(A) tail for coronavirus defective genome replicationQ33787055
The cellular chaperone heat shock protein 90 facilitates Flock House virus RNA replication in Drosophila cellsQ33788928
Mitochondrial aconitase binds to the 3' untranslated region of the mouse hepatitis virus genomeQ33838446
Genome-wide RNAi screen reveals a specific sensitivity of IRES-containing RNA viruses to host translation inhibitionQ33848936
Heterogeneous nuclear ribonucleoprotein a1 binds to the 3'-untranslated region and mediates potential 5'-3'-end cross talks of mouse hepatitis virus RNA.Q33851638
Identification and characterization of a host protein required for efficient template selection in viral RNA replicationQ33897668
RNA-dependent RNA polymerases, viruses, and RNA silencingQ33959192
Dengue virus-induced autophagy regulates lipid metabolismQ34024721
Sterol structure and membrane functionQ34055411
Brome mosaic virus 1a nucleoside triphosphatase/helicase domain plays crucial roles in recruiting RNA replication templates.Q34092871
Membrane-shaping host reticulon proteins play crucial roles in viral RNA replication compartment formation and functionQ34136651
Dengue virus nonstructural protein 3 redistributes fatty acid synthase to sites of viral replication and increases cellular fatty acid synthesisQ34182803
Suppression of viral RNA recombination by a host exoribonucleaseQ34434892
Host factors involved in West Nile virus replication.Q34498823
Mutation of host DnaJ homolog inhibits brome mosaic virus negative-strand RNA synthesisQ34756426
Systematic, genome-wide identification of host genes affecting replication of a positive-strand RNA virusQ34791544
Inhibition of phospholipid biosynthesis decreases the activity of the tombusvirus replicase and alters the subcellular localization of replication proteinsQ35023984
Assembly of alphavirus replication complexes from RNA and protein components in a novel trans-replication system in mammalian cellsQ35076756
Brome mosaic virus RNA replication: revealing the role of the host in RNA virus replicationQ35090240
Direct inhibition of tombusvirus plus-strand RNA synthesis by a dominant negative mutant of a host metabolic enzyme, glyceraldehyde-3-phosphate dehydrogenase, in yeast and plantsQ35192852
RNA-binding proteins that inhibit RNA virus infectionQ35652395
Sterol molecule: structure, biosynthesis, and functionQ35802288
A functional heat shock protein 90 chaperone is essential for efficient flock house virus RNA polymerase synthesis in Drosophila cellsQ35947748
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)137-149
P577publication date2011-12-19
P1433published inNature Reviews MicrobiologyQ1071797
P1476titleThe dependence of viral RNA replication on co-opted host factors
P478volume10

Reverse relations

cites work (P2860)
Q34167914A Co-Opted DEAD-Box RNA helicase enhances tombusvirus plus-strand synthesis
Q35652151A Kinome-Wide Small Interfering RNA Screen Identifies Proviral and Antiviral Host Factors in Severe Acute Respiratory Syndrome Coronavirus Replication, Including Double-Stranded RNA-Activated Protein Kinase and Early Secretory Pathway Proteins.
Q45325903A decade of RNA virus metagenomics is (not) enough.
Q92932335A helitron-induced RabGDIα variant causes quantitative recessive resistance to maize rough dwarf disease
Q37428861A human proteome microarray identifies that the heterogeneous nuclear ribonucleoprotein K (hnRNP K) recognizes the 5' terminal sequence of the hepatitis C virus RNA
Q47549169A model of OSBP-mediated cholesterol supply to Aichi virus RNA replication sites involving protein-protein interactions among viral proteins, ACBD3, OSBP, VAP-A/B, and SAC1.
Q64238739ACBD3 Is an Essential Pan-enterovirus Host Factor That Mediates the Interaction between Viral 3A Protein and Cellular Protein PI4KB
Q42531573ADP ribosylation factor 1 plays an essential role in the replication of a plant RNA virus.
Q35641395Activation of Tomato Bushy Stunt Virus RNA-Dependent RNA Polymerase by Cellular Heat Shock Protein 70 Is Enhanced by Phospholipids In Vitro
Q37347377Affinity Purification of the Hepatitis C Virus Replicase Identifies Valosin-Containing Protein, a Member of the ATPases Associated with Diverse Cellular Activities Family, as an Active Virus Replication Modulator.
Q45354647Alfalfa mosaic virus replicase proteins, P1 and P2, localize to the tonoplast in the presence of virus RNA.
Q45359585An inhibitory function of WW domain-containing host proteins in RNA virus replication
Q38713351Analysis of the miRNA profile in C6/36 cells persistently infected with dengue virus type 2.
Q38242934Antiviral innate immunity and stress granule responses
Q42096806Arenavirus infection induces discrete cytosolic structures for RNA replication
Q54215855Assembly-hub function of ER-localized SNARE proteins in biogenesis of tombusvirus replication compartment.
Q41169421Authentic in vitro replication of two tombusviruses in isolated mitochondrial and endoplasmic reticulum membranes
Q52338889Beclin1 restricts RNA virus infection in plants through suppression and degradation of the viral polymerase.
Q26748849Biogenesis and architecture of arterivirus replication organelles
Q92343279Blocking tombusvirus replication through the antiviral functions of DDX17-like RH30 DEAD-box helicase
Q90287166CRISPR/Cas9-Mediated Knockout of DNAJC14 Verifies This Chaperone as a Pivotal Host Factor for RNA Replication of Pestiviruses
Q26767366Cell-Free and Cell-Based Approaches to Explore the Roles of Host Membranes and Lipids in the Formation of Viral Replication Compartment Induced by Tombusviruses
Q41620237Cellular Ubc2/Rad6 E2 ubiquitin-conjugating enzyme facilitates tombusvirus replication in yeast and plants
Q54456155Characterization of dominant-negative and temperature-sensitive mutants of tombusvirus replication proteins affecting replicase assembly.
Q36724437Cholesterol-Enriched Domain Formation Induced by Viral-Encoded, Membrane-Active Amphipathic Peptide.
Q37238813Co-infection with two strains of Brome mosaic bromovirus reveals common RNA recombination sites in different hosts
Q35347251Co-opted oxysterol-binding ORP and VAP proteins channel sterols to RNA virus replication sites via membrane contact sites.
Q47154680Co-opting ATP-generating glycolytic enzyme PGK1 phosphoglycerate kinase facilitates the assembly of viral replicase complexes.
Q39015802Comparative interactomics for virus-human protein-protein interactions: DNA viruses versus RNA viruses
Q41557233Conserved motifs in a tombusvirus polymerase modulate genome replication, subgenomic transcription, and amplification of defective interfering RNAs
Q34896333Construction of a synthetic infectious cDNA clone of Grapevine Algerian latent virus (GALV-Nf) and its biological activity in Nicotiana benthamiana and grapevine plants
Q35563566Coordinated function of cellular DEAD-box helicases in suppression of viral RNA recombination and maintenance of viral genome integrity
Q99711639Correlation Analysis of Expression Profile and Quantitative iTRAQ-LC-MS/MS Proteomics Reveals Resistance Mechanism Against TuMV in Chinese Cabbage (Brassica rapa ssp. pekinensis)
Q36111700Coxsackievirus can exploit LC3 in both autophagy-dependent and -independent manners in vivo
Q34398719Current progress in antiviral strategies
Q37336768Cyclophilin A binds to the viral RNA and replication proteins, resulting in inhibition of tombusviral replicase assembly
Q39244702Cyclophilin inhibitors block arterivirus replication by interfering with viral RNA synthesis
Q89708514DHX9 interacts with APOBEC3B and attenuates the anti-HBV effect of APOBEC3B
Q40130410Defining Hsp70 Subnetworks in Dengue Virus Replication Reveals Key Vulnerability in Flavivirus Infection
Q54244659Demarcation of Viral Shelters Results in Destruction by Membranolytic GTPases: Antiviral Function of Autophagy Proteins and Interferon-Inducible GTPases.
Q41574302Differential roles of Hsp70 and Hsp90 in the assembly of the replicase complex of a positive-strand RNA plant virus.
Q57128184Drawing on disorder: How viruses use histone mimicry to their advantage
Q59351850Dynamin-like proteins of endocytosis in plants are co-opted by potyviruses to enhance virus infection
Q36167663Enrichment of Phosphatidylethanolamine in Viral Replication Compartments via Co-opting the Endosomal Rab5 Small GTPase by a Positive-Strand RNA Virus
Q59132097Exploring the Diversity of Mechanisms Associated With Plant Tolerance to Virus Infection
Q46033198Expression and Cleavage of Middle East Respiratory Syndrome Coronavirus nsp3-4 Polyprotein Induce the Formation of Double-Membrane Vesicles That Mimic Those Associated with Coronaviral RNA Replication.
Q36363212Flavivirus replication complex assembly revealed by DNAJC14 functional mapping.
Q92835570Flavors of Flaviviral RNA Structure: towards an Integrated View of RNA Function from Translation through Encapsidation
Q35862238Formation of Potato Virus A-Induced RNA Granules and Viral Translation Are Interrelated Processes Required for Optimal Virus Accumulation
Q64057357Functional conservation of EXA1 among diverse plant species for the infection by a family of plant viruses
Q40715118Functionality of host proteins in Cucumber mosaic virus replication: GAPDH is obligatory to promote interaction between replication-associated proteins
Q36715201Genetic recombination in plant-infecting messenger-sense RNA viruses: overview and research perspectives
Q89823968Global Analysis of Alternative Splicing Difference in Peripheral Immune Organs between Tongcheng Pigs and Large White Pigs Artificially Infected with PRRSV In Vivo
Q36124078Global Profiling of the Cellular Alternative RNA Splicing Landscape during Virus-Host Interactions
Q28533294Global organization of a positive-strand RNA virus genome
Q45354357Guanylylation-competent replication proteins of Tomato mosaic virus are disulfide-linked
Q40348078Harnessing host ROS-generating machinery for the robust genome replication of a plant RNA virus.
Q40565578Heat shock protein 90 is essential for replication of porcine circovirus type 2 in PK-15 cells
Q39147004Heat shock protein-90-beta facilitates enterovirus 71 viral particles assembly
Q41105900Hepatitis B virus hijacks CTHRC1 to evade host immunity and maintain replication
Q29871458Hepatitis C virus triggers Golgi fragmentation and autophagy through the immunity-related GTPase M.
Q64100570Host Lipids in Positive-Strand RNA Virus Genome Replication
Q51740098Hsc70-2 is required for Beet black scorch virus infection through interaction with replication and capsid proteins.
Q59350701Human astroviruses: in silico analysis of the untranslated region and putative binding sites of cellular proteins
Q47202187Identification and Molecular Characterization of the Chloroplast Targeting Domain of Turnip yellow mosaic virus Replication Proteins
Q34488462Identification of Host Cell Factors Associated with Astrovirus Replication in Caco-2 Cells
Q39288517Identification of RNA-protein interaction networks involved in the norovirus life cycle
Q28481496Identification of common biological pathways and drug targets across multiple respiratory viruses based on human host gene expression analysis
Q45355460Identification of domains in p27 auxiliary replicase protein essential for its association with the endoplasmic reticulum membranes in Red clover necrotic mosaic virus.
Q41843369Identification of novel host factors via conserved domain search: Cns1 cochaperone is a novel restriction factor of tombusvirus replication in yeast
Q50076636Identification of small non-coding RNA classes expressed in swine whole blood during HP-PRRSV infection
Q41552179Importin-α-mediated nucleolar localization of potato mop-top virus TRIPLE GENE BLOCK1 (TGB1) protein facilitates virus systemic movement, whereas TGB1 self-interaction is required for cell-to-cell movement in Nicotiana benthamiana.
Q35105634Inactivation of the host lipin gene accelerates RNA virus replication through viral exploitation of the expanded endoplasmic reticulum membrane
Q34769274Increased long chain acyl-Coa synthetase activity and fatty acid import is linked to membrane synthesis for development of picornavirus replication organelles
Q35037040Infection with Usutu virus induces an autophagic response in mammalian cells.
Q40913679Interferon-inducible cholesterol-25-hydroxylase restricts hepatitis C virus replication through blockage of membranous web formation
Q90616823Interviral Recombination between Plant, Insect, and Fungal RNA Viruses: Role of the Intracellular Ca2+/Mn2+ Pump
Q26864643Intracellular coordination of potyviral RNA functions in infection
Q43050335Investigating the role of viral integral membrane proteins in promoting the assembly of nepovirus and comovirus replication factories.
Q92877163Junín virus induces autophagy in human A549 cells
Q90697168Killing two birds with one stone: How do Plant Viruses Break Down Plant Defenses and Manipulate Cellular Processes to Replicate Themselves?
Q36224063Lipids and RNA virus replication
Q37123203Magnetic fractionation and proteomic dissection of cellular organelles occupied by the late replication complexes of Semliki Forest virus
Q44270229Membrane association of Wuhan nodavirus protein A is required for its ability to accumulate genomic RNA1 template
Q42250630Methylation of translation elongation factor 1A by the METTL10-like See1 methyltransferase facilitates tombusvirus replication in yeast and plants.
Q35760516Molecular chaperone Hsp90 is a therapeutic target for noroviruses
Q41851727Morphological and biochemical characterization of the membranous hepatitis C virus replication compartment
Q26745979Multiple Targets of Salicylic Acid and Its Derivatives in Plants and Animals
Q27468796Network analysis reveals common host protein/s modulating pathogenesis of neurotropic viruses
Q28076019Next-Generation Sequencing and Genome Editing in Plant Virology
Q35157229Noncanonical role for the host Vps4 AAA+ ATPase ESCRT protein in the formation of Tomato bushy stunt virus replicase
Q42198052Nonsense-mediated decay serves as a general viral restriction mechanism in plants
Q34261735Novel indole-2-carboxamide compounds are potent broad-spectrum antivirals active against western equine encephalitis virus in vivo.
Q41619446Novel mechanism of regulation of tomato bushy stunt virus replication by cellular WW-domain proteins
Q37336680Nucleolin interacts with the dengue virus capsid protein and plays a role in formation of infectious virus particles
Q34467155Origins and evolution of viruses of eukaryotes: The ultimate modularity
Q34535820PTB binds to the 3' untranslated region of the human astrovirus type 8: a possible role in viral replication
Q92815846Perception of double-stranded RNA in plant antiviral immunity
Q28547576Phosphatidic acid produced by phospholipase D promotes RNA replication of a plant RNA virus
Q45325472Phytopathogenic fungus hosts a plant virus: A naturally occurring cross-kingdom viral infection
Q35644690Plant Translation Elongation Factor 1Bβ Facilitates Potato Virus X (PVX) Infection and Interacts with PVX Triple Gene Block Protein 1.
Q38538455Plant Translation Factors and Virus Resistance
Q39932740Plum Pox Virus 6K1 Protein Is Required for Viral Replication and Targets the Viral Replication Complex at the Early Stage of Infection
Q40314991Protein composition of 6K2-induced membrane structures formed during Potato virus A infection.
Q41844933Proteome-wide overexpression of host proteins for identification of factors affecting tombusvirus RNA replication: an inhibitory role of protein kinase C.
Q38100767RNA synthetic mechanisms employed by diverse families of RNA viruses
Q35377680RNA virus replication depends on enrichment of phosphatidylethanolamine at replication sites in subcellular membranes
Q28538998RNABindRPlus: a predictor that combines machine learning and sequence homology-based methods to improve the reliability of predicted RNA-binding residues in proteins
Q33743801Rab18 facilitates dengue virus infection by targeting fatty acid synthase to sites of viral replication
Q37517465Recent Advances in the Discovery of Norovirus Therapeutics
Q28079696Recessive Resistance to Plant Viruses: Potential Resistance Genes Beyond Translation Initiation Factors
Q40600302Recruitment of Arabidopsis RNA Helicase AtRH9 to the Viral Replication Complex by Viral Replicase to Promote Turnip Mosaic Virus Replication
Q38329850Recruitment of PI4KIIIβ to coxsackievirus B3 replication organelles is independent of ACBD3, GBF1, and Arf1.
Q61800024Recruitment of Vps34 PI3K and enrichment of PI3P phosphoinositide in the viral replication compartment is crucial for replication of a positive-strand RNA virus
Q45992375Riboproteomics: A versatile approach for the identification of host protein interaction network in plant pathogenic noncoding RNAs.
Q36284655Rice grassy stunt virus p5 interacts with two protein components of the plant-specific CBL-CIPK Ca+2 signaling network of rice
Q36694129Role of Viral RNA and Co-opted Cellular ESCRT-I and ESCRT-III Factors in Formation of Tombusvirus Spherules Harboring the Tombusvirus Replicase
Q38012549Role of host reticulon proteins in rearranging membranes for positive-strand RNA virus replication.
Q40167625Roles of superoxide anion and hydrogen peroxide during replication of two unrelated plant RNA viruses in Nicotiana benthamiana.
Q90573473Screening Legionella effectors for antiviral effects reveals Rab1 GTPase as a proviral factor coopted for tombusvirus replication
Q35895743Screening a yeast library of temperature-sensitive mutants reveals a role for actin in tombusvirus RNA recombination
Q56877861Shaping the flavivirus replication complex: It is curvaceous!
Q47341835Similar roles for yeast Dbp2 and Arabidopsis RH20 DEAD-box RNA helicases to Ded1 helicase in tombusvirus plus-strand synthesis
Q39013842Sterol Binding by the Tombusviral Replication Proteins Is Essential for Replication in Yeast and Plants
Q92703078Taking over Cellular Energy-Metabolism for TBSV Replication: The High ATP Requirement of an RNA Virus within the Viral Replication Organelle
Q42981144Teicoplanin therapy leading to a significant decrease in viral load in a patient with chronic hepatitis C.
Q33602797Template role of double-stranded RNA in tombusvirus replication
Q36559787The GEF1 proton-chloride exchanger affects tombusvirus replication via regulation of copper metabolism in yeast
Q27468643The Golgi associated ERI3 is a Flavivirus host factor
Q37703027The Involvement of Heat Shock Proteins in the Establishment of Tomato Yellow Leaf Curl Virus Infection
Q59807365The Role of the Chloroplast in the Replication of Positive-Sense Single-Stranded Plant RNA Viruses
Q64093475The Tug-of-War between Plants and Viruses: Great Progress and Many Remaining Questions
Q35745401The Vesicle-Forming 6K2 Protein of Turnip Mosaic Virus Interacts with the COPII Coatomer Sec24a for Viral Systemic Infection
Q55300594The antiviral protein Viperin suppresses T7 promoter dependent RNA synthesis-possible implications for its antiviral activity.
Q40526779The cellular decapping activators LSm1, Pat1, and Dhh1 control the ratio of subgenomic to genomic Flock House virus RNAs
Q35151994The expanding functions of cellular helicases: the tombusvirus RNA replication enhancer co-opts the plant eIF4AIII-like AtRH2 and the DDX5-like AtRH5 DEAD-box RNA helicases to promote viral asymmetric RNA replication
Q34059324The hop-like stress-induced protein 1 cochaperone is a novel cell-intrinsic restriction factor for mitochondrial tombusvirus replication.
Q99402510The importance of virion-incorporated cellular RNA-Binding Proteins in viral particle assembly and infectivity
Q42233041The p33 auxiliary replicase protein of Cucumber necrosis virus targets peroxisomes and infection induces de novo peroxisome formation from the endoplasmic reticulum.
Q42127165The proteasomal Rpn11 metalloprotease suppresses tombusvirus RNA recombination and promotes viral replication via facilitating assembly of the viral replicase complex
Q36978646The resistance protein Tm-1 inhibits formation of a Tomato mosaic virus replication protein-host membrane protein complex.
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Q38243326Tombusvirus-yeast interactions identify conserved cell-intrinsic viral restriction factors
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Q100991957Transcriptomic and Epigenomic Dynamics of Honey Bees in Response to Lethal Viral Infection
Q43813181Translation elongation factor 1B (eEF1B) is an essential host factor for Tobacco mosaic virus infection in plants
Q59354894Unconventional RNA-binding proteins step into the virus-host battlefront
Q61797305Versatility of Cyclophilins in Plant Growth and Survival: A Case Study in
Q38638220Viral Interference and Persistence in Mosquito-Borne Flaviviruses
Q27315960Viral Replication Protein Inhibits Cellular Cofilin Actin Depolymerization Factor to Regulate the Actin Network and Promote Viral Replicase Assembly
Q38367799Viral sensing of the subcellular environment regulates the assembly of new viral replicase complexes during the course of infection
Q38043543Virus factories: biogenesis and structural design
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Q92242764What proteomics can reveal about plant-virus interactions? Photosynthesis-related proteins on the spotlight
Q51745893Wolbachia-mediated virus blocking in mosquito cells is dependent on XRN1-mediated viral RNA degradation and influenced by viral replication rate.
Q36281839Y-Box Binding Protein 1 Stabilizes Hepatitis C Virus NS5A via Phosphorylation-Mediated Interaction with NS5A To Regulate Viral Propagation.
Q34475303Yeast screens for host factors in positive-strand RNA virus replication based on a library of temperature-sensitive mutants
Q61053650Zika Virus Dependence on Host Hsp70 Provides a Protective Strategy against Infection and Disease
Q39561354p33-Independent activation of a truncated p92 RNA-dependent RNA polymerase of Tomato bushy stunt virus in yeast cell-free extract