Translating novel strategies for cardioprotection: the Hatter Workshop Recommendations

scientific article

Translating novel strategies for cardioprotection: the Hatter Workshop Recommendations is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1050848579
P356DOI10.1007/S00395-010-0121-4
P8608Fatcat IDrelease_ymgdr3jebvbsfbzbjptgobxxgu
P932PMC publication ID2965360
P698PubMed publication ID20865418
P5875ResearchGate publication ID46414683

P50authorGerd HeuschQ29869951
Hans Erik BøtkerQ31229530
Derek M. YellonQ33528795
Gary F. BaxterQ41880070
Derek HausenloyQ42409890
Rainer SchulzQ47430697
Sean M. DavidsonQ56988847
John Malcolm WalkerQ68022597
Masafumi KitakazeQ88336037
Mihaela M MocanuQ90899693
Sandrine LecourQ114429989
Michel OvizeQ114430026
P2093author name stringRobert Bell
Richard Shannon
Gail Walkinshaw
James Downey
Robert Mentzer
P2860cites workRemote ischaemic conditioning before hospital admission, as a complement to angioplasty, and effect on myocardial salvage in patients with acute myocardial infarction: a randomised trialQ33535020
Infliximab attenuates early myocardial dysfunction after resuscitation in a swine cardiac arrest modelQ33753939
Cyclosporine A at reperfusion reduces infarct size in pigsQ33791098
Myocardial reperfusion injury.Q34687124
Cardiac Remote Ischemic Preconditioning in Coronary Stenting (CRISP Stent) Study: a prospective, randomized control trial.Q34935546
Cardiac protection during acute myocardial infarction: where do we stand in 2004?Q35840326
Myocardial protection at a crossroads: the need for translation into clinical therapyQ35844649
Remote ischaemic postconditioning protects the heart during acute myocardial infarction in pigsQ35954778
Myocardial protection with volatile anaesthetic agents during coronary artery bypass surgery: a meta-analysisQ36515887
Interaction of cardiovascular risk factors with myocardial ischemia/reperfusion injury, preconditioning, and postconditioning.Q37019662
Pathophysiology of myocardial infarction: protection by ischemic pre- and postconditioning.Q37111331
Remote ischaemic preconditioning: underlying mechanisms and clinical application.Q37154560
Limitation of myocardial infarct size in the clinical setting: current status and challenges in translating animal experiments into clinical therapyQ37248348
Preconditioning the diabetic human myocardiumQ37311040
Loss of cardioprotection with ageing.Q37379567
Ischemic postconditioning: experimental models and protocol algorithmsQ37526561
Coronary microembolization: from bedside to bench and back to bedsideQ37626321
Cardiac preconditioning for ischaemia: lost in translation.Q37675573
Postconditioning and protection from reperfusion injury: where do we stand? Position paper from the Working Group of Cellular Biology of the Heart of the European Society of CardiologyQ37744271
Sodium-hydrogen exchange inhibition by cariporide to reduce the risk of ischemic cardiac events in patients undergoing coronary artery bypass grafting: results of the EXPEDITION studyQ38501716
Cardioprotection with postconditioning: loss of efficacy in murine models of type-2 and type-1 diabetesQ39284051
Aging mouse hearts are refractory to infarct size reduction with post-conditioningQ39321486
Prognostic significance and determinants of myocardial salvage assessed by cardiovascular magnetic resonance in acute reperfused myocardial infarctionQ39868576
Remote ischaemic preconditioning protects against cardiopulmonary bypass-induced tissue injury: a preclinical studyQ42831243
Post-conditioning with cyclosporine A fails to reduce the infarct size in an in vivo porcine modelQ43067949
Cyclosporine does not reduce myocardial infarct size in a porcine ischemia-reperfusion modelQ43076963
Cyclosporine A administered during reperfusion fails to restore cardioprotection in prediabetic Zucker obese rats in vivoQ43264111
Glimepiride, a novel sulfonylurea, does not abolish myocardial protection afforded by either ischemic preconditioning or diazoxideQ43653267
Effect of aging on the ability of preconditioning to protect rat hearts from ischemia-reperfusion injuryQ43737906
Quantification of myocardial area at risk with T2-weighted CMR: comparison with contrast-enhanced CMR and coronary angiographyQ43769708
Association between CK-MB elevation after percutaneous or surgical revascularization and three-year mortalityQ44244533
Effects of glucagon-like peptide-1 in patients with acute myocardial infarction and left ventricular dysfunction after successful reperfusionQ44774818
Cardiac troponin T elevation after coronary artery bypass grafting is associated with increased one-year mortalityQ45089770
One hour reperfusion is enough to assess function and infarct size with TTC staining in Langendorff rat model.Q45998298
Myocardium at risk after acute infarction in humans on cardiac magnetic resonance: quantitative assessment during follow-up and validation with single-photon emission computed tomography.Q46011772
K(ATP) channel activation reduces the severity of postresuscitation myocardial dysfunctionQ46059291
Ischemic postconditioning in pigs: no causal role for RISK activation.Q46225223
Effect of cyclosporine on reperfusion injury in acute myocardial infarctionQ46453592
Mitochondrial permeability transition pore as a target for cardioprotection in the human heartQ46551313
Remote ischemic preconditioning of the recipient reduces myocardial ischemia-reperfusion injury of the denervated donor heart via a Katp channel-dependent mechanismQ46562294
Preconditioning the diabetic heart: the importance of Akt phosphorylationQ46620654
Postconditioning the human heartQ46722557
Long-term benefit of postconditioningQ46758924
Human atrial natriuretic peptide and nicorandil as adjuncts to reperfusion treatment for acute myocardial infarction (J-WIND): two randomised trialsQ46928598
Systematic analysis of functional and structural changes after coronary microembolization: a cardiac magnetic resonance imaging studyQ48031201
Thoracic Surgery Directors Association Award. Cobalt chloride pretreatment attenuates myocardial apoptosis after hypothermic circulatory arrestQ48336927
Remote ischemic preconditioning reduces myocardial injury after coronary artery bypass surgery with crystalloid cardioplegic arrestQ48356691
Effect of remote ischaemic preconditioning on myocardial injury in patients undergoing coronary artery bypass graft surgery: a randomised controlled trialQ48572279
Intracoronary KAI-9803 as an adjunct to primary percutaneous coronary intervention for acute ST-segment elevation myocardial infarction.Q50647596
Intermittent peripheral tissue ischemia during coronary ischemia reduces myocardial infarction through a KATP-dependent mechanism: first demonstration of remote ischemic perconditioning.Q51093594
Bidirectional role of tumor necrosis factor-alpha in coronary microembolization: progressive contractile dysfunction versus delayed protection against infarction.Q51093781
Retrospective determination of the area at risk for reperfused acute myocardial infarction with T2-weighted cardiac magnetic resonance imaging: histopathological and displacement encoding with stimulated echoes (DENSE) functional validations.Q51228456
Adenosine A1 agonist at reperfusion trial (AART): results of a three-center, blinded, randomized, controlled experimental infarct study.Q51360512
Rat and rabbit heart infarction: effects of anesthesia, perfusate, risk zone, and method of infarct sizing.Q51619864
Cardioprotection by postconditioning is lost in WOKW rats with metabolic syndrome: role of glycogen synthase kinase 3beta.Q54785513
Early Metoprolol Administration Before Coronary Reperfusion Results in Increased Myocardial SalvageQ56986728
Preconditioning in isolated superfused human muscleQ60343971
Changes in collateral channel filling immediately after controlled coronary artery occlusion by an angioplasty balloon in human subjectsQ67276951
Indications for fibrinolytic therapy in suspected acute myocardial infarction: collaborative overview of early mortality and major morbidity results from all randomised trials of more than 1000 patients. Fibrinolytic Therapy Trialists' (FTT) CollaboQ72665772
The mitochondrial permeability transition pore: its fundamental role in mediating cell death during ischaemia and reperfusionQ73256108
Dynamic progression of contractile and endothelial dysfunction and infarct extension in the late phase of reperfusionQ73265301
Relationship between postoperative cardiac troponin I levels and outcome of cardiac surgeryQ79137159
Cardioprotection: nitric oxide, protein kinases, and mitochondriaQ79780264
Postconditioning protects human atrial muscle through the activation of the RISK pathwayQ80423743
Cardioprotection by ischemic postconditioning is lost in aged and STAT3-deficient miceQ81514899
Inhibition of mitochondrial permeability transition pore opening: the Holy Grail of cardioprotectionQ82471465
Neglect of the coronary circulation: some critical remarks on problems in the translation of cardioprotectionQ84105681
Inhibition of mitochondrial permeability transition to prevent the post-cardiac arrest syndrome: a pre-clinical studyQ84133516
P433issue6
P921main subjectworkshopQ27556165
P1104number of pages10
P304page(s)677-686
P577publication date2010-09-24
P1433published inBasic Research in CardiologyQ2453360
P1476titleTranslating novel strategies for cardioprotection: the Hatter Workshop Recommendations
P478volume105

Reverse relations

cites work (P2860)
Q36011190A novel role for mitochondrial sphingosine-1-phosphate produced by sphingosine kinase-2 in PTP-mediated cell survival during cardioprotection.
Q37907329A role for GRK2 in myocardial ischemic injury: indicators of a potential future therapy and diagnostic
Q36694644Acute erythropoietin cardioprotection is mediated by endothelial response.
Q44261013Aging attenuates the protective effect of ischemic preconditioning against endothelial ischemia-reperfusion injury in humans.
Q48243115Aleglitazar, a Balanced Dual PPARα and -γ Agonist, Protects the Heart Against Ischemia-Reperfusion Injury
Q37638828Aleglitazar, a dual peroxisome proliferator-activated receptor-α and -γ agonist, protects cardiomyocytes against the adverse effects of hyperglycaemia
Q47350464Aliskiren and Valsartan reduce myocardial AT1 receptor expression and limit myocardial infarct size in diabetic mice
Q44966048Alpha-1 antitrypsin inhibits caspase-1 and protects from acute myocardial ischemia-reperfusion injury
Q34091132Alterations in the interleukin-1/interleukin-1 receptor antagonist balance modulate cardiac remodeling following myocardial infarction in the mouse
Q47387978Apelin-13 limits infarct size and improves cardiac postischemic mechanical recovery only if given after ischemia.
Q37570347At the crossroads from bench to bedside: luteolin is a promising pharmacological agent against myocardial ischemia reperfusion injury
Q37973049Autophagy as a therapeutic target for ischaemia /reperfusion injury? Concepts, controversies, and challenges
Q35944872Blockade of electron transport at the onset of reperfusion decreases cardiac injury in aged hearts by protecting the inner mitochondrial membrane
Q35922588CTGF/CCN2 Postconditioning Increases Tolerance of Murine Hearts towards Ischemia-Reperfusion Injury
Q45247800Cardiac-derived adiponectin induced by long-term insulin treatment ameliorates myocardial ischemia/reperfusion injury in type 1 diabetic mice via AMPK signaling
Q36420890Cardiomyocyte-restricted overexpression of extracellular superoxide dismutase increases nitric oxide bioavailability and reduces infarct size after ischemia/reperfusion
Q37912844Cardioprotection by ivabradine through heart rate reduction and beyond.
Q36802290Cardioprotection by mild hypothermia during ischemia involves preservation of ERK activity
Q26866366Cardioprotection during cardiac surgery
Q35881667Cardioprotection of recombinant human MG53 protein in a porcine model of ischemia and reperfusion injury
Q54573276Class A scavenger receptor attenuates myocardial infarction-induced cardiomyocyte necrosis through suppressing M1 macrophage subset polarization.
Q37912861Clinical efforts to reduce myocardial infarct size--the next step
Q37140973Conditioning the heart to prevent myocardial reperfusion injury during PPCI
Q43999555Coronary microembolization during early reperfusion: infarct extension, but protection by ischaemic postconditioning
Q37895373Coronary no reflow
Q38872391Depressed Exercise Peak Ejection Rate Detected on Ambulatory Radionuclide Monitoring Reflects End-Stage Cardiac Inotropic Reserve and Predicts Mortality in Ischaemic Cardiomyopathy.
Q34004756Determination of the myocardial area at risk with pre- versus post-reperfusion imaging techniques in the pig model
Q47968505Diazoxide postconditioning induces mitochondrial protein S-nitrosylation and a redox-sensitive mitochondrial phosphorylation/translocation of RISK elements: no role for SAFE.
Q38194363Dipeptidyl peptidase IV inhibitors and ischemic myocardial injury
Q41892420Disrupting the EMMPRIN (CD147)-cyclophilin A interaction reduces infarct size and preserves systolic function after myocardial ischemia and reperfusion
Q49449899Does growth differentiation factor 11 protect against myocardial ischaemia/reperfusion injury? A hypothesis
Q45146419Does mild hypothermia protect against reperfusion injury? The debate continues
Q24289195ESC working group cellular biology of the heart: position paper: improving the preclinical assessment of novel cardioprotective therapies
Q38479165Effect of remote ischemic preconditioning on clinical outcomes in patients undergoing coronary artery bypass graft surgery (ERICCA): rationale and study design of a multi-centre randomized double-blinded controlled clinical trial.
Q46589926Effect of sulfur dioxide preconditioning on rat myocardial ischemia/reperfusion injury by inducing endoplasmic reticulum stress
Q64943661Effects of Cardiac Hypertrophy, Diabetes, Aging, and Pregnancy on the Cardioprotective Effects of Postconditioning in Male and Female Rats.
Q37871976Efficacy of cardioprotective 'conditioning' strategies in aging and diabetic cohorts: the co-morbidity conundrum
Q35928926Endothelial-cardiomyocyte crosstalk enhances pharmacological cardioprotection
Q42861824Ethanolamine is a novel STAT-3 dependent cardioprotective agent
Q58447894Exenatide reduces reperfusion injury in patients with ST-segment elevation myocardial infarction
Q54424234Exercise-induced cardioprotection is mediated by a bloodborne, transferable factor.
Q54568467Failure to recapture cardioprotection with high-dose atorvastatin in coronary artery bypass surgery: a randomised controlled trial.
Q28073354From basic mechanisms to clinical applications in heart protection, new players in cardiovascular diseases and cardiac theranostics: meeting report from the third international symposium on "New frontiers in cardiovascular research"
Q40258000Gene transfer as a strategy to achieve permanent cardioprotection I: rAAV-mediated gene therapy with inducible nitric oxide synthase limits infarct size 1 year later without adverse functional consequences
Q84732981Genetic background, gender, age, body temperature, and arterial blood pH have a major impact on myocardial infarct size in the mouse and need to be carefully measured and/or taken into account: results of a comprehensive analysis of determinants of
Q36974257Genetic deletion of uncoupling protein 3 exaggerates apoptotic cell death in the ischemic heart leading to heart failure.
Q38061499Genetics and genomics of ischemic tolerance: focus on cardiac and cerebral ischemic preconditioning
Q54463866Glimepiride treatment facilitates ischemic preconditioning in the diabetic heart.
Q34215980HIF-1α signaling activation by post-ischemia treatment with astragaloside IV attenuates myocardial ischemia-reperfusion injury
Q35860938Hydroxychloroquine Protects against Cardiac Ischaemia/Reperfusion Injury In Vivo via Enhancement of ERK1/2 Phosphorylation
Q47944673Impact of lifelong exercise training on endothelial ischemia-reperfusion and ischemic preconditioning in humans
Q36355264Influence of tumour necrosis factor alpha on the outcome of ischaemic postconditioning in the presence of obesity and diabetes
Q54513464Inhibition of RIP1-dependent necrosis prevents adverse cardiac remodeling after myocardial ischemia-reperfusion in vivo.
Q92593739Investigation of the underlying hub genes and mechanisms of reperfusion injury in patients undergoing coronary artery bypass graft surgery by integrated bioinformatic analyses
Q38722304Ischaemic conditioning and reperfusion injury.
Q38427068Ischaemic conditioning: are we there yet?
Q35631620Ischemic preconditioning: the role of mitochondria and aging
Q87074288Mediation of dopamine D2 receptors activation in post-conditioning-attenuated cardiomyocyte apoptosis
Q36371672Meeting report from the 2nd International Symposium on New Frontiers in Cardiovascular Research. Protecting the cardiovascular system from ischemia: between bench and bedside
Q44188620Melatonin, given at the time of reperfusion, prevents ventricular arrhythmias in isolated hearts from fructose-fed rats and spontaneously hypertensive rats.
Q46736926MicroRNA-155 aggravates ischemia-reperfusion injury by modulation of inflammatory cell recruitment and the respiratory oxidative burst
Q60056507Microvesicles and Exosomes in Local and Distant Communication with the Heart
Q54621218Molecular and cellular mechanisms involved in cardiac remodeling after acute myocardial infarction.
Q28543466Myocardial creatine levels do not influence response to acute oxidative stress in isolated perfused heart
Q36497176Myocardial ischemia-reperfusion injury: a neglected therapeutic target.
Q41703806Necrostatin-1 alleviates reperfusion injury following acute myocardial infarction in pigs.
Q37007953New horizons in cardioprotection: recommendations from the 2010 National Heart, Lung, and Blood Institute Workshop
Q35016000New technique of local ischemic preconditioning induction without repetitive aortic cross-clamping in cardiac surgery.
Q46402883Notch1 cardioprotection in myocardial ischemia/reperfusion involves reduction of oxidative/nitrative stress
Q47178073Novel Synthesized Radical-Containing Nanoparticles Limit Infarct Size Following Ischemia and Reperfusion in Canine Hearts
Q39739258Optimal timing of hypothermia in relation to myocardial reperfusion
Q51317623PTEN upregulation may explain the development of insulin resistance and type 2 diabetes with high dose statins.
Q47388835Pioglitazone limits myocardial infarct size, activates Akt, and upregulates cPLA2 and COX-2 in a PPAR-γ-independent manner
Q37988319Pleiotropic effects of dronedarone on ischemia/reperfusion injury in heart and brain.
Q47620961Postconditioning with glucagon like peptide-2 reduces ischemia/reperfusion injury in isolated rat hearts: role of survival kinases and mitochondrial KATP channels
Q53083983Preclinical studies of human disease: time to take methodological quality seriously.
Q48212106Protection by remote ischemic preconditioning during coronary artery bypass graft surgery with isoflurane but not propofol - a clinical trial
Q35893836Protective Effect of Creatine Elevation against Ischaemia Reperfusion Injury Is Retained in the Presence of Co-Morbidities and during Cardioplegia
Q54520877Protective effect of ischemic postconditioning against ischemia reperfusion-induced myocardium oxidative injury in IR rats.
Q42749210Reduction of myocardial infarct size by dronedarone in pigs--a pleiotropic action?
Q48266257Remote intermittent ischemia before coronary artery bypass graft surgery: a strategy to reduce injury and inflammation?
Q38639332Remote ischaemic conditioning-a new paradigm of self-protection in the brain.
Q43758053Remote ischaemic postconditioning: does it protect against ischaemic damage in percutaneous coronary revascularisation? Randomised placebo-controlled clinical trial
Q34458416Remote ischemic conditioning.
Q37912853Remote ischemic conditioning: a clinical trial's update
Q26828968Remote ischemic conditioning: from experimental observation to clinical application: report from the 8th Biennial Hatter Cardiovascular Institute Workshop
Q36680922Remote ischemic preconditioning confers late protection against myocardial ischemia-reperfusion injury in mice by upregulating interleukin-10.
Q50863981Right ventricular hypertrophy and failure abolish cardioprotection by ischaemic pre-conditioning.
Q35864123Role of Mitogen-Activated Protein Kinases in Myocardial Ischemia-Reperfusion Injury during Heart Transplantation
Q42293459Role of carbonyl sulfide in acute lung injury following limb ischemia/reperfusion in rats
Q38573070Statin-Induced Cardioprotection Against Ischemia-Reperfusion Injury: Potential Drug-Drug Interactions. Lesson to be Learnt by Translating Results from Animal Models to the Clinical Settings
Q26825240Stenting technique, gender, and age are associated with cardioprotection by ischaemic postconditioning in primary coronary intervention: a systematic review of 10 randomized trials
Q38202410Stromal derived factor 1α: a chemokine that delivers a two-pronged defence of the myocardium.
Q47348822Supplemental oxygen in patients without hypoxia in ST segment elevation myocardial infarction increases myocardial injury and infarct size
Q38010782Targeting reperfusion injury in acute myocardial infarction: a review of reperfusion injury pharmacotherapy
Q37738596Targeting reperfusion injury in patients with ST-segment elevation myocardial infarction: trials and tribulations.
Q37375425The ERK1/2 signaling pathway is involved in sulfur dioxide preconditioning-induced protection against cardiac dysfunction in isolated perfused rat heart subjected to myocardial ischemia/reperfusion
Q54429906The GTN patch: a simple and effective new approach to cardioprotection?
Q53287714The PI3K/Akt, p38MAPK, and JAK2/STAT3 signaling pathways mediate the protection of SO2 against acute lung injury induced by limb ischemia/reperfusion in rats.
Q51124858The RIPOST-MI study, assessing remote ischemic perconditioning alone or in combination with local ischemic postconditioning in ST-segment elevation myocardial infarction.
Q36031657The alpha1 isoform of soluble guanylate cyclase regulates cardiac contractility but is not required for ischemic preconditioning
Q47255415The antiarrhythmic dipeptide ZP1609 (danegaptide) when given at reperfusion reduces myocardial infarct size in pigs
Q37850517The in-situ pig heart with regional ischemia/reperfusion - ready for translation.
Q54497300The mechanism of beta-adrenergic preconditioning: roles for adenosine and ROS during triggering and mediation.
Q38274962The mitochondrial permeability transition pore and its role in myocardial ischemia reperfusion injury.
Q37926558The potential effects of anti-diabetic medications on myocardial ischemia-reperfusion injury
Q37892335The therapeutic potential of ischemic conditioning: an update
Q35043452Therapeutic potential of intermittent hypoxia: a matter of dose
Q38318626Trans-system mechanisms against ischemic myocardial injury
Q38075417Translating cardioprotection for patient benefit: position paper from the Working Group of Cellular Biology of the Heart of the European Society of Cardiology.
Q38612855Translational failure of anti-inflammatory compounds for myocardial infarction: a meta-analysis of large animal models
Q38026951Volatile anaesthetics and cardioprotection: lessons from animal studies.
Q38108537What is the role of erythropoietin in acute myocardial infarct? Bridging the gap between experimental models and clinical trials
Q54343158β3 adrenergic receptor selective stimulation during ischemia/reperfusion improves cardiac function in translational models through inhibition of mPTP opening in cardiomyocytes.

Search more.