IL-17RA signaling reduces inflammation and mortality during Trypanosoma cruzi infection by recruiting suppressive IL-10-producing neutrophils

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IL-17RA signaling reduces inflammation and mortality during Trypanosoma cruzi infection by recruiting suppressive IL-10-producing neutrophils is …
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scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PPAT.1002658
P8608Fatcat IDrelease_iawer3l7trh3xeqd6qgzts7kvu
P932PMC publication ID3343119
P698PubMed publication ID22577359
P5875ResearchGate publication ID224940521

P2093author name stringAdriana Gruppi
Jimena Tosello Boari
Hugo Cejas
Carolina Lucía Montes
Daniela Andrea Bermejo
Eva Virginia Acosta Rodríguez
María Carolina Amezcua Vesely
Maria Cecilia Ramello
P2860cites workNeutrophil depletion exacerbates experimental Chagas' disease in BALB/c, but protects C57BL/6 mice through modulating the Th1/Th2 dichotomy in different directions.Q54015362
Endogenous IFN-gamma is required for resistance to acute Trypanosoma cruzi infection in mice.Q54296214
Coactivation of Syk kinase and MyD88 adaptor protein pathways by bacteria promotes regulatory properties of neutrophils.Q54709609
The dual nature of TH17 cells: shifting the focus to functionQ56607716
IL-10 is required to prevent immune hyperactivity during infection with Trypanosoma cruziQ58843169
The regulatory CD4+CD25+ T cells have a limited role on pathogenesis of infection with Trypanosoma cruziQ58844686
IL-17-mediated regulation of innate and acquired immune response against pulmonary Mycobacterium bovis bacille Calmette-Guerin infectionQ79880519
An IL-17F/A heterodimer protein is produced by mouse Th17 cells and induces airway neutrophil recruitmentQ79912740
Use of Ly6G-specific monoclonal antibody to deplete neutrophils in miceQ81332054
Cloning and characterization of IL-17B and IL-17C, two new members of the IL-17 cytokine familyQ22011116
Gamma-interferon transcriptionally regulates an early-response gene containing homology to platelet proteinsQ24300179
Identification and characterization of macrophage inflammatory protein 2Q24338941
The biological functions of T helper 17 cell effector cytokines in inflammationQ24614431
T helper 17 cells promote cytotoxic T cell activation in tumor immunityQ24646584
Structure and signalling in the IL-17 receptor familyQ24648045
Interleukin 25 regulates type 2 cytokine-dependent immunity and limits chronic inflammation in the gastrointestinal tractQ24673592
Neutrophil-activating properties of the melanoma growth-stimulatory activityQ24683011
A novel cytokine receptor-ligand pair. Identification, molecular characterization, and in vivo immunomodulatory activityQ28119212
Myeloid-derived suppressor cells as regulators of the immune systemQ28131637
Cutting edge: IL-17D, a novel member of the IL-17 family, stimulates cytokine production and inhibits hemopoiesisQ28208761
IL-25 induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivoQ28213431
Cutting edge: interleukin 17 signals through a heteromeric receptor complexQ28247130
IL-25 enhances allergic airway inflammation by amplifying a TH2 cell-dependent pathway in miceQ28261605
Interleukin-17 family members and inflammationQ28287876
Invariant NKT cells modulate the suppressive activity of IL-10-secreting neutrophils differentiated with serum amyloid AQ28294740
Identification of functional roles for both IL-17RB and IL-17RA in mediating IL-25-induced activitiesQ28584827
IL-17B and IL-17C are associated with TNF-alpha production and contribute to the exacerbation of inflammatory arthritisQ28587556
IL-17 family cytokines and the expanding diversity of effector T cell lineagesQ29619361
Neutrophils in the activation and regulation of innate and adaptive immunityQ29620082
Profile of central and effector memory T cells in the progression of chronic human chagas diseaseQ33501719
IL-17 produced during Trypanosoma cruzi infection plays a central role in regulating parasite-induced myocarditisQ33532584
Clinical protection from falciparum malaria correlates with neutrophil respiratory bursts induced by merozoites opsonized with human serum antibodiesQ33548663
Interleukin-17/interleukin-17 receptor-mediated signaling is important for generation of an optimal polymorphonuclear response against Toxoplasma gondii infectionQ33556845
Tumor necrosis factor alpha-mediated toxic shock in Trypanosoma cruzi-infected interleukin 10-deficient miceQ33597343
Innate IL-17-producing cells: the sentinels of the immune systemQ33608575
How are antibodies involved in the protective mechanism of susceptible mice infected with T. cruzi?Q33864240
Functional specialization of interleukin-17 family membersQ34025860
Proinflammatory T helper type 17 cells are effective B-cell helpersQ34069686
Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defenseQ34087551
Type 1 chemokine receptor expression in Chagas' disease correlates with morbidity in cardiac patients.Q34194841
Critical role of IL-25 in nematode infection-induced alterations in intestinal function.Q34332461
Effects of the PAF receptor antagonist UK74505 on local and remote reperfusion injuries following ischaemia of the superior mesenteric artery in the rat.Q35043050
Endogenous CD4(+) CD25(+) regulatory T cells have a limited role in the control of Trypanosoma cruzi infection in miceQ35689168
IL-25 regulates Th17 function in autoimmune inflammationQ36228942
Neutrophils cascading their way to inflammationQ36315860
Absence of donor Th17 leads to augmented Th1 differentiation and exacerbated acute graft-versus-host diseaseQ36843812
Commensal-dependent expression of IL-25 regulates the IL-23-IL-17 axis in the intestine.Q36916407
Interleukin-17 as an effector molecule of innate and acquired immunity against infectionsQ37038277
A protective function for interleukin 17A in T cell-mediated intestinal inflammationQ37260173
Polymorphonuclear neutrophils and T lymphocytes: strange bedfellows or brothers in arms?Q37602369
The innate immune response to Trypanosoma cruzi infectionQ37720281
Interleukin-17 and its expanding biological functions.Q37728837
Interleukin-17 and its target genes: mechanisms of interleukin-17 function in diseaseQ37735334
Interleukin-25: a two-edged sword in the control of immune-inflammatory responsesQ37770345
IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogensQ39459097
Evidence that development of severe cardiomyopathy in human Chagas' disease is due to a Th1-specific immune responseQ39730057
Chronic Chagas' disease cardiomyopathy patients display an increased IFN-gamma response to Trypanosoma cruzi infection.Q40788068
Expression of serum amyloid A3 mRNA by inflammatory macrophages exposed to membrane glycoconjugates from Trypanosoma cruzi.Q40921506
Novel highly sensitive IL-10-beta-lactamase reporter mouse reveals cells of the innate immune system as a substantial source of IL-10 in vivoQ41427050
Immunological control of Trypanosoma cruzi infection and pathogenesis of Chagas' disease.Q41617474
Trypanosoma cruzi: cytokine effects on macrophage trypanocidal activityQ41902933
IL-17 is necessary for host protection against acute-phase Trypanosoma cruzi infectionQ43012403
WSX-1 is required for resistance to Trypanosoma cruzi infection by regulation of proinflammatory cytokine productionQ44721986
Endogenous interferon-gamma, macrophage activation, and murine host defense against acute infection with Trypanosoma cruziQ46130734
Inhibition of monocyte-derived inflammatory cytokines by IL-25 occurs via p38 Map kinase-dependent induction of Socs-3.Q46609770
Interleukin 17 receptor signaling is deleterious during Toxoplasma gondii infection in susceptible BL6 miceQ48153766
Interleukin-17C promotes Th17 cell responses and autoimmune disease via interleukin-17 receptor E.Q49335379
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue4
P921main subjectTrypanosoma cruziQ150162
P304page(s)e1002658
P577publication date2012-04-26
P1433published inPLOS PathogensQ283209
P1476titleIL-17RA signaling reduces inflammation and mortality during Trypanosoma cruzi infection by recruiting suppressive IL-10-producing neutrophils
P478volume8

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