| scholarly article | Q13442814 |
| P2093 | author name string | G Gazzinelli | |
| R Correa-Oliveira | |||
| L M G Bahia-Oliveira | |||
| O A Martins-Filho | |||
| J A S Gomes | |||
| M O C Rocha | |||
| P2860 | cites work | Immunological and clinical evaluation of chagasic patients subjected to chemotherapy during the acute phase of Trypanosoma cruzi infection 14-30 years ago | Q28142046 |
| Gamma interferon response in secondary Leishmania major infection: role of CD8+ T cells | Q33607724 | ||
| Chagas disease etiology: autoimmunity or parasite persistence? | Q33632782 | ||
| The pathogenesis of Chagas' disease: when autoimmune and parasite-specific immune responses meet. | Q34463172 | ||
| CD4-mediated and CD8-mediated cytotoxic and proliferative immune responses to Toxoplasma gondii in seropositive humans | Q35526423 | ||
| Modulation of chagasic cardiomyopathy by interleukin-4: dissociation between inflammation and tissue parasitism | Q35746981 | ||
| Interleukin 10 and interferon gamma regulation of experimental Trypanosoma cruzi infection | Q36230811 | ||
| CD4+ cytolytic T cell clone confers protection against murine malaria | Q36353821 | ||
| Association of CD4+ T cell-dependent, interferon-gamma-mediated necrosis of the small intestine with genetic susceptibility of mice to peroral infection with Toxoplasma gondii | Q36367127 | ||
| The indeterminate form of human chronic Chagas' disease A clinical epidemiological review | Q38215235 | ||
| Correlation between Trypanosoma cruzi parasitism and myocardial inflammatory infiltrate in human chronic chagasic myocarditis: Light microscopy and immunohistochemical findings | Q39067405 | ||
| Interleukin-12 enhances in vivo parasiticidal effect of benznidazole during acute experimental infection with a naturally drug-resistant strain of Trypanosoma cruzi | Q39559044 | ||
| Chronic Chagas' disease cardiomyopathy patients display an increased IFN-gamma response to Trypanosoma cruzi infection. | Q40788068 | ||
| A heart-specific CD4+ T-cell line obtained from a chronic chagasic mouse induces carditis in heart-immunized mice and rejection of normal heart transplants in the absence of Trypanosoma cruzi | Q40821845 | ||
| Enhanced cytotoxicity of IFN-gamma-producing CD4+ cytotoxic T lymphocytes specific for T. gondii-infected human melanoma cells. | Q41389059 | ||
| The microbicidal activity of interferon-gamma-treated macrophages against Trypanosoma cruzi involves an L-arginine-dependent, nitrogen oxide-mediated mechanism inhibitable by interleukin-10 and transforming growth factor-beta | Q41600919 | ||
| Immunological control of Trypanosoma cruzi infection and pathogenesis of Chagas' disease. | Q41617474 | ||
| Anti-CD4 abrogates rejection and reestablishes long-term tolerance to syngeneic newborn hearts grafted in mice chronically infected with Trypanosoma cruzi | Q41823109 | ||
| Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies. | Q44729936 | ||
| IFN-gamma in human Chagas' disease: protection or pathology? | Q47758411 | ||
| Induction of cell-mediated immunity during early stages of infection with intracellular protozoa | Q47758446 | ||
| Cytokines as determinants of disease and disease interactions | Q47758460 | ||
| Characterization of cytokine production in murine Trypanosoma cruzi infection by in situ immunocytochemistry: lack of association between susceptibility and type 2 cytokine production. | Q54154405 | ||
| IL-10 mediates susceptibility to Trypanosoma cruzi infection. | Q54193255 | ||
| In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-gamma and TNF-alpha | Q57339973 | ||
| Association of an increase in CD8+ T cells with the presence of Trypanosoma cruzi antigens in chronic, human, chagasic myocarditis | Q58843120 | ||
| An in situ quantitative immunohistochemical study of cytokines and IL-2R+ in chronic human chagasic myocarditis: correlation with the presence of myocardial Trypanosoma cruzi antigens | Q58843149 | ||
| Cytokine mRNA profile of peripheral blood mononuclear cells isolated from individuals with Trypanosoma cruzi chronic infection | Q58843253 | ||
| Characterization of inflammatory infiltrates in chronic chagasic myocardial lesions: presence of tumor necrosis factor-alpha+ cells and dominance of granzyme A+, CD8+ lymphocytes | Q58844274 | ||
| In vivo administration of recombinant IFN-gamma induces macrophage activation, and prevents acute disease, immune suppression, and death in experimental Trypanosoma cruzi infections | Q58845682 | ||
| Systematic mapping of hearts from chronic chagasic patients: the association between the occurrence of histopathological lesions and Trypanosoma cruzi antigens | Q58846721 | ||
| Interferon-gamma Production by Human T Cells and Natural Killer Cells In Vitro in Response to Antigens from the Two Intracellular Pathogens Mycobacterium tuberculosis and Leishmania major | Q59294737 | ||
| Detection of intracellular cytokines by flow cytometry | Q70590309 | ||
| Immune responses during human Schistosomiasis mansoni. VIII. Differential in vitro cellular responsiveness to adult worm and schistosomular tegumental preparations | Q71700061 | ||
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Chagas disease | Q649558 |
| cardiomyopathy | Q847583 | ||
| P304 | page(s) | 1185-1193 | |
| P577 | publication date | 2003-03-01 | |
| P1433 | published in | Infection and Immunity | Q6029193 |
| P1476 | title | Evidence that development of severe cardiomyopathy in human Chagas' disease is due to a Th1-specific immune response | |
| P478 | volume | 71 |
| Q35581314 | A Two-Component DNA-Prime/Protein-Boost Vaccination Strategy for Eliciting Long-Term, Protective T Cell Immunity against Trypanosoma cruzi |
| Q60920705 | Activation of Human CD11b B1 B-Cells by -Derived Proteins Is Associated With Protective Immune Response in Human Chagas Disease |
| Q92241525 | Advances in understanding the role of adipose tissue and mitochondrial oxidative stress in Trypanosoma cruzi infection |
| Q42497203 | Are increased frequency of macrophage-like and natural killer (NK) cells, together with high levels of NKT and CD4+CD25high T cells balancing activated CD8+ T cells, the key to control Chagas' disease morbidity? |
| Q93053187 | Association between cytokines and two circulating micro-RNAs and development of premature ventricular contractions-induced cardiomyopathy |
| Q46816770 | Association of caspase-1 polymorphisms with Chagas cardiomyopathy among individuals in Santa Cruz, Bolivia |
| Q54234613 | BALB/c and C57BL/6 Mice Cytokine Responses to Trypanosoma cruzi Infection Are Independent of Parasite Strain Infectivity. |
| Q37597057 | Back to the future in Chagas disease: from animal models to patient cohort studies, progress in immunopathogenesis research. |
| Q34069688 | Benzonidazole therapy modulates interferon-γ and M2 muscarinic receptor autoantibody responses in Trypanosoma cruzi-infected children |
| Q93062588 | Betulinic Acid Derivative BA5, Attenuates Inflammation and Fibrosis in Experimental Chronic Chagas Disease Cardiomyopathy by Inducing IL-10 and M2 Polarization |
| Q35864379 | Biologic and genetics aspects of chagas disease at endemic areas |
| Q39003348 | Blood Gene Signatures of Chagas Cardiomyopathy With or Without Ventricular Dysfunction |
| Q34280628 | Blood leukocytes from benznidazole-treated indeterminate chagas disease patients display an overall type-1-modulated cytokine profile upon short-term in vitro stimulation with Trypanosoma cruzi antigens |
| Q33914939 | CD8(+) T cell-mediated immunity during Trypanosoma cruzi infection: a path for vaccine development? |
| Q27346448 | CD8+ T-cells expressing interferon gamma or perforin play antagonistic roles in heart injury in experimental Trypanosoma cruzi-elicited cardiomyopathy |
| Q55364024 | CD86 Expression by Monocytes Influences an Immunomodulatory Profile in Asymptomatic Patients with Chronic Chagas Disease. |
| Q92251637 | CXCR3 chemokine receptor guides Trypanosoma cruzi-specific T-cells triggered by DNA/adenovirus ASP2 vaccine to heart tissue after challenge |
| Q44113294 | Cardiac damage induced by immunization with heat-killed Trypanosoma cruzi is not antibody mediated |
| Q35085050 | Cardiac gene expression profiling provides evidence for cytokinopathy as a molecular mechanism in Chagas' disease cardiomyopathy. |
| Q33825602 | Cardiac involvement with parasitic infections |
| Q41485954 | Cellular and genetic mechanisms involved in the generation of protective and pathogenic immune responses in human Chagas disease |
| Q46695507 | Cellular immune response from Chagasic patients to CRA or FRA recombinant antigens of Trypanosoma cruzi |
| Q34125557 | Chagas disease cardiomyopathy: immunopathology and genetics |
| Q39226738 | Chagas disease immunogenetics: elusive markers of disease progression |
| Q38238078 | Chagas disease: still many unsolved issues |
| Q37310959 | Chagas' disease: an update on immune mechanisms and therapeutic strategies |
| Q43659552 | Characterization of CD4⁺ cytotoxic lymphocytes and apoptosis markers induced by Trypanossoma cruzi infection |
| Q91975356 | Circulating T Follicular Helper Cell Abnormalities Associated to Different Clinical Forms of Chronic Chagas Disease |
| Q34492588 | Contribution of NK, NK T, gamma delta T, and alpha beta T cells to the gamma interferon response required for liver protection against Trypanosoma cruzi |
| Q37151780 | Current concepts in immunoregulation and pathology of human Chagas disease |
| Q31164394 | Cytokine production but lack of proliferation in peripheral blood mononuclear cells from chronic Chagas' disease cardiomyopathy patients in response to T. cruzi ribosomal P proteins |
| Q35114499 | Cytokine profiling in Chagas disease: towards understanding the association with infecting Trypanosoma cruzi discrete typing units (a BENEFIT TRIAL sub-study). |
| Q34251395 | Deficient regulatory T cell activity and low frequency of IL-17-producing T cells correlate with the extent of cardiomyopathy in human Chagas' disease. |
| Q41552272 | Depletion of regulatory T cells decreases cardiac parasitosis and inflammation in experimental Chagas disease |
| Q45298259 | Development of chronic cardiomyopathy in canine Chagas disease correlates with high IFN-gamma, TNF-alpha, and low IL-10 production during the acute infection phase |
| Q57475606 | Diagnosis and Management of Chagas Cardiomyopathy in the United States |
| Q34193529 | Different infective forms trigger distinct immune response in experimental Chagas disease |
| Q42369872 | Ebi3 Prevents Trypanosoma cruzi-Induced Myocarditis by Dampening IFN-γ-Driven Inflammation |
| Q34478887 | Effects of omega-3 polyunsaturated fatty acid supplementation in patients with chronic chagasic cardiomyopathy: study protocol for a randomized controlled trial |
| Q34603215 | Elevated serum levels of macrophage migration inhibitory factor are associated with progressive chronic cardiomyopathy in patients with Chagas disease |
| Q34992879 | Evaluating Chagas disease progression and cure through blood-derived biomarkers: a systematic review |
| Q64102301 | Evidence of Different IL-1β Activation Pathways in Innate Immune Cells From Indeterminate and Cardiac Patients With Chronic Chagas Disease |
| Q36637937 | Evolution and pathology in chagas disease--a review |
| Q40127854 | Evolution of anti-Trypanosoma cruzi antibody production in patients with chronic Chagas disease: Correlation between antibody titers and development of cardiac disease severity. |
| Q51345333 | Expression of co-stimulatory molecules CD80 and CD86 is altered in CD14 + HLA-DR + monocytes from patients with Chagas disease following induction by Trypanosoma cruzi recombinant antigens. |
| Q35065274 | Genetic susceptibility to Chagas disease cardiomyopathy: involvement of several genes of the innate immunity and chemokine-dependent migration pathways. |
| Q33809208 | Heat-killed Trypanosoma cruzi induces acute cardiac damage and polyantigenic autoimmunity |
| Q48262765 | Human complement receptor type 1 (CR1) protein levels and genetic variants in chronic Chagas Disease |
| Q35061481 | Human leucocyte antigen-G (HLA-G) and its murine functional homolog Qa2 in the Trypanosoma cruzi Infection. |
| Q35048439 | IL-10 inhibits the NF-κB and ERK/MAPK-mediated production of pro-inflammatory mediators by up-regulation of SOCS-3 in Trypanosoma cruzi-infected cardiomyocytes |
| Q35659197 | IL-10 limits parasite burden and protects against fatal myocarditis in a mouse model of Trypanosoma cruzi infection |
| Q92863084 | IL-10/STAT3/SOCS3 Axis Is Involved in the Anti-inflammatory Effect of Benznidazole |
| Q33532584 | IL-17 produced during Trypanosoma cruzi infection plays a central role in regulating parasite-induced myocarditis |
| Q34266045 | IL-17RA signaling reduces inflammation and mortality during Trypanosoma cruzi infection by recruiting suppressive IL-10-producing neutrophils |
| Q50044327 | Identification of Anti-Trypanosoma cruzi Lead Compounds with Putative Immunomodulatory Activity |
| Q57275770 | IgG isotype profile is correlated with cardiomegaly in Beagle dogs infected with distinct Trypanosoma cruzi strains |
| Q53879463 | Immunization with cytoplasmic repetitive antigen and flagellar repetitive antigen of Trypanosoma cruzi stimulates a cellular immune response in mice. |
| Q37597069 | Immunological and non-immunological effects of cytokines and chemokines in the pathogenesis of chronic Chagas disease cardiomyopathy |
| Q51775764 | Immunological imbalance between IFN-gamma and IL-10 levels in the sera of patients with the cardiac form of Chagas disease. |
| Q41528104 | Immunoregulatory actions of melatonin and zinc during chronic Trypanosoma cruzi infection |
| Q36006382 | Immunoregulatory mechanisms in Chagas disease: modulation of apoptosis in T-cell mediated immune responses |
| Q34084644 | Immunoregulatory networks in human Chagas disease |
| Q24602785 | Immunotherapy of Trypanosoma cruzi infection with DNA vaccines in mice |
| Q50978237 | Impairment in natural killer cells editing of immature dendritic cells by infection with a virulent Trypanosoma cruzi population. |
| Q41745518 | Increase in the expression of CD4 + CD25+ lymphocytic T cells in the indeterminate clinical form of human Chagas disease after stimulation with recombinant antigens of Trypanosoma cruzi |
| Q54534950 | Increased activities of cardiac matrix metalloproteinases matrix metalloproteinase (MMP)-2 and MMP-9 are associated with mortality during the acute phase of experimental Trypanosoma cruzi infection. |
| Q37190915 | Increased myeloperoxidase activity and protein nitration are indicators of inflammation in patients with Chagas' disease |
| Q58843971 | Increased type 1 chemokine expression in experimental Chagas disease correlates with cardiac pathology in beagle dogs |
| Q33997924 | Induction of IL-12 production in human peripheral monocytes by Trypanosoma cruzi Is mediated by glycosylphosphatidylinositol-anchored mucin-like glycoproteins and potentiated by IFN- γ and CD40-CD40L interactions |
| Q36385476 | Induction of cardiac autoimmunity in Chagas heart disease: a case for molecular mimicry |
| Q35994773 | Innate and acquired immunity in the pathogenesis of Chagas disease |
| Q90467218 | Innate immune receptors over expression correlate with chronic chagasic cardiomyopathy and digestive damage in patients |
| Q37597066 | Innate immunity and regulatory T-cells in human Chagas disease: what must be understood? |
| Q35915997 | Interferon-gamma induces chronic active myocarditis and cardiomyopathy in transgenic mice. |
| Q34179046 | Interferon-γ and other inflammatory mediators in cardiomyocyte signaling during Chagas disease cardiomyopathy |
| Q92405091 | Intermediate Monocytes and Cytokine Production Associated With Severe Forms of Chagas Disease |
| Q34531351 | Low doses of simvastatin therapy ameliorate cardiac inflammatory remodeling in Trypanosoma cruzi-infected dogs. |
| Q37264609 | Matrix metalloproteinases 2 and 9 are differentially expressed in patients with indeterminate and cardiac clinical forms of Chagas disease |
| Q36383902 | Methodological approach to the ex vivo expansion and detection of T. cruzi-specific T cells from chronic Chagas disease patients. |
| Q28083346 | Modulation of Trypanosoma cruzi-specific T-cell responses after chemotherapy for chronic Chagas disease |
| Q34476397 | Myocardial chemokine expression and intensity of myocarditis in Chagas cardiomyopathy are controlled by polymorphisms in CXCL9 and CXCL10. |
| Q34053139 | Myocardial gene expression of T-bet, GATA-3, Ror-γt, FoxP3, and hallmark cytokines in chronic Chagas disease cardiomyopathy: an essentially unopposed TH1-type response |
| Q39244146 | Participation of TLR2 and TLR4 in Cytokines Production by Patients with Symptomatic and Asymptomatic Chronic Chagas Disease. |
| Q40291208 | Pathogenesis of Chagas disease: time to move on. |
| Q57789637 | Pathology and Pathogenesis of Chagas Heart Disease |
| Q43251669 | Perforin-expressing cytotoxic cells contribute to chronic cardiomyopathy in Trypanosoma cruzi infection |
| Q47346569 | Phenotypic and functional characteristics of CD28+ and CD28- cells from chagasic patients: distinct repertoire and cytokine expression |
| Q35112727 | Plasma cytokine expression is associated with cardiac morbidity in chagas disease |
| Q35036373 | Polymorphic sites at the immunoregulatory CTLA-4 gene are associated with chronic chagas disease and its clinical manifestations. |
| Q98177690 | Polymorphisms in Genes Affecting Interferon-γ Production and Th1 T Cell Differentiation Are Associated With Progression to Chagas Disease Cardiomyopathy |
| Q42102813 | Potential Role of Carvedilol in the Cardiac Immune Response Induced by Experimental Infection with Trypanosoma cruzi |
| Q34075123 | Presence of antigen-experienced T cells with low grade of differentiation and proliferative potential in chronic Chagas disease myocarditis |
| Q33501719 | Profile of central and effector memory T cells in the progression of chronic human chagas disease |
| Q41970393 | Regulation of Trypanosoma cruzi-induced myocarditis by programmed death cell receptor 1. |
| Q54255041 | Regulatory Lymphoid and Myeloid Cells Determine the Cardiac Immunopathogenesis of Trypanosoma cruzi Infection. |
| Q33927456 | Regulatory T cells phenotype in different clinical forms of Chagas' disease |
| Q64102179 | Role of Aryl Hydrocarbon Receptor (AhR) in the Regulation of Immunity and Immunopathology During Infection |
| Q34021911 | Role of the IFNG +874T/A polymorphism in Chagas disease in a Colombian population |
| Q33955413 | Selective decrease of components of the creatine kinase system and ATP synthase complex in chronic Chagas disease cardiomyopathy |
| Q37021200 | Sequence variation in the IL4 gene and resistance to Trypanosoma cruzi infection in Bolivians. |
| Q48099205 | Specific activation of CD4- CD8- double-negative T cells by Trypanosoma cruzi-derived glycolipids induces a proinflammatory profile associated with cardiomyopathy in Chagas patients. |
| Q39329438 | Synergic and antagonistic relationship between MMP-2 and MMP-9 with fibrosis and inflammation in Chagas' cardiomyopathy. |
| Q91996563 | T-Cell Immunophenotyping and Cytokine Production Analysis in Patients with Chagas Disease 4 Years after Benznidazole Treatment |
| Q58593739 | The Role of Co-Stimulatory Molecules in Chagas Disease |
| Q58705710 | The Unsolved Jigsaw Puzzle of the Immune Response in Chagas Disease |
| Q37198750 | The heart of the matter: protection of the myocardium from T cells |
| Q39253448 | The metabogenic role of iron in chronic chagasic cardiac failure |
| Q44537491 | The monocyte chemoattractant protein-1 gene polymorphism is associated with cardiomyopathy in human chagas disease |
| Q34341377 | The receptor Slamf1 on the surface of myeloid lineage cells controls susceptibility to infection by Trypanosoma cruzi |
| Q51608812 | The relationship between heart rate variability and serum cytokines in chronic chagasic patients with persistent parasitemia. |
| Q40124290 | Therapeutic effects of sphingosine kinase inhibitor N,N-dimethylsphingosine (DMS) in experimental chronic Chagas disease cardiomyopathy |
| Q49215894 | Treatment with a New Peroxisome Proliferator-Activated Receptor Gamma Agonist, Pyridinecarboxylic Acid Derivative, Increases Angiogenesis and Reduces Inflammatory Mediators in the Heart of Trypanosoma cruzi-Infected Mice |
| Q47883122 | Troponin T autoantibodies correlate with chronic cardiomyopathy in human Chagas disease |
| Q55314147 | Trypanosoma cruzi Exploits Wnt Signaling Pathway to Promote Its Intracellular Replication in Macrophages. |
| Q42118281 | Trypanosoma cruzi infection induces differential modulation of costimulatory molecules and cytokines by monocytes and T cells from patients with indeterminate and cardiac Chagas' disease |
| Q27304622 | Trypanosoma cruzi infection is a potent risk factor for non-alcoholic steatohepatitis enhancing local and systemic inflammation associated with strong oxidative stress and metabolic disorders |
| Q34194841 | Type 1 chemokine receptor expression in Chagas' disease correlates with morbidity in cardiac patients. |
| Q47162312 | Unconventional Pro-inflammatory CD4+ T Cell Response in B Cell-Deficient Mice Infected with Trypanosoma cruzi. |
| Q64910433 | Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes as a Model to Study Trypanosoma cruzi Infection. |
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