Are increased frequency of macrophage-like and natural killer (NK) cells, together with high levels of NKT and CD4+CD25high T cells balancing activated CD8+ T cells, the key to control Chagas' disease morbidity?

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Are increased frequency of macrophage-like and natural killer (NK) cells, together with high levels of NKT and CD4+CD25high T cells balancing activated CD8+ T cells, the key to control Chagas' disease morbidity? is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1365-2249.2006.03123.X
P932PMC publication ID1942003
P698PubMed publication ID16792677
P5875ResearchGate publication ID6991171

P50authorRodrigo Lima MassaraQ58762944
Marta de LanaQ58874953
P2093author name stringO A Martins-Filho
A Teixeira-Carvalho
R Sathler-Avelar
J C P Dias
D M Vitelli-Avelar
J D Borges
P S Lage
S M Elói-Santos
P2860cites workCD4+CD25+ T regulatory cells inhibit cytotoxic activity of T CD8+ and NK lymphocytes in the direct cell-to-cell interactionQ33205892
Influence of acute-phase parasite load on pathology, parasitism, and activation of the immune system at the late chronic phase of Chagas' diseaseQ34000030
The mucin-like glycoprotein super-family of Trypanosoma cruzi: structure and biological roles.Q34264871
The biology of human natural killer-cell subsetsQ34430869
Chemokines, inflammation and Trypanosoma cruzi infection.Q34660986
Tumor necrosis factor alpha mediates resistance to Trypanosoma cruzi infection in mice by inducing nitric oxide production in infected gamma interferon-activated macrophagesQ35457307
Regulation of Trypanosoma cruzi infection in mice by gamma interferon and interleukin 10: role of NK cellsQ35462159
Interleukin-12 mediates resistance to Trypanosoma cruzi in mice and is produced by murine macrophages in response to live trypomastigotesQ35494931
Pivotal role of interleukin-12 and interferon-gamma axis in controlling tissue parasitism and inflammation in the heart and central nervous system during Trypanosoma cruzi infectionQ35750253
Going both ways: immune regulation via CD1d-dependent NKT cellsQ35951531
Innate and acquired immunity in the pathogenesis of Chagas diseaseQ35994773
The importance of aberrant T-cell responses in Chagas disease.Q36101419
Evidence that development of severe cardiomyopathy in human Chagas' disease is due to a Th1-specific immune responseQ39730057
Monocytes from patients with indeterminate and cardiac forms of Chagas' disease display distinct phenotypic and functional characteristics associated with morbidityQ40014457
Activation of Toll-like receptor-2 by glycosylphosphatidylinositol anchors from a protozoan parasiteQ40797228
Glycoconjugates isolated from Trypanosoma cruzi but not from Leishmania species membranes trigger nitric oxide synthesis as well as microbicidal activity in IFN-gamma-primed macrophagesQ41049635
Immunological control of Trypanosoma cruzi infection and pathogenesis of Chagas' disease.Q41617474
Human natural killer cells: a unique innate immunoregulatory role for the CD56(bright) subsetQ43600819
Human B cell activation by autologous NK cells is regulated by CD40-CD40 ligand interaction: role of memory B cells and CD5+ B cellsQ43803672
The Trypanosoma cruzi trans-sialidase is a T cell-independent B cell mitogen and an inducer of non-specific Ig secretionQ43898130
The proinflammatory CD14+CD16+DR++ monocytes are a major source of TNF.Q43925988
Acute Chagas' disease: immunohistochemical characteristics of T cell infiltrate and its relationship with T. cruzi parasitic antigens.Q44892957
Phenotypic features of peripheral blood leucocytes during early stages of human infection with Trypanosoma cruziQ47365806
Multiple sites of post-activation CD8+ T cell disposalQ48787238
TNF-alpha controls intrahepatic T cell apoptosis and peripheral T cell numbers.Q51998749
Activated T and B lymphocytes in peripheral blood of patients with Chagas' disease.Q54210625
CD4+CD25high regulatory cells in human peripheral bloodQ56905059
Proliferative and Cytotoxic capabilities of CD16�CD56?and CD16�CD56+ natural killer cellsQ57609607
Chagas' disease: Trypanosoma cruzi vs. the host immune systemQ57842381
The human liver contains multiple populations of NK cells, T cells, and CD3+CD56+ natural T cells with distinct cytotoxic activities and Th1, Th2, and Th0 cytokine secretion patternsQ58143619
Cytokine responses in Trypanosoma cruzi-infected children in ParaguayQ58832376
Association of an increase in CD8+ T cells with the presence of Trypanosoma cruzi antigens in chronic, human, chagasic myocarditisQ58843120
Influence of parasite presence on the immunologic profile of peripheral blood mononuclear cells from chagasic patients after specific drug therapyQ58843278
Characterization of inflammatory infiltrates in chronic chagasic myocardial lesions: presence of tumor necrosis factor-alpha+ cells and dominance of granzyme A+, CD8+ lymphocytesQ58844274
Chagasic patients with indeterminate clinical form of the disease have high frequencies of circulating CD3+CD16-CD56+ natural killer T cells and CD4+CD25High regulatory T lymphocytesQ58845519
Control of Chagas diseaseQ58846339
Chagas' diseaseQ58846530
Phenotypic characterization of the inflammatory cells in chagasic megaoesophagusQ58846549
Heterogeneity of human blood monocytes: the CD14+ CD16+ subpopulationQ71648991
Glycoinositolphospholipids purified from Trypanosoma cruzi stimulate Ig production in vitroQ71833938
Cord blood CD16+56- cells with low lytic activity are possible precursors of mature natural killer cellsQ73814808
Trypanosoma cruzi surface mucin TcMuc-e2 expressed on higher eukaryotic cells induces human T cell anergy, which is reversibleQ77590319
P433issue1
P921main subjectmacrophageQ184204
Chagas diseaseQ649558
P304page(s)81-92
P577publication date2006-07-01
P1433published inClinical and Experimental ImmunologyQ15716708
P1476titleAre increased frequency of macrophage-like and natural killer (NK) cells, together with high levels of NKT and CD4+CD25high T cells balancing activated CD8+ T cells, the key to control Chagas' disease morbidity?
P478volume145

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cites work (P2860)
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