Deficient regulatory T cell activity and low frequency of IL-17-producing T cells correlate with the extent of cardiomyopathy in human Chagas' disease.

scientific article

Deficient regulatory T cell activity and low frequency of IL-17-producing T cells correlate with the extent of cardiomyopathy in human Chagas' disease. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PNTD.0001630
P932PMC publication ID3335880
P698PubMed publication ID22545173
P5875ResearchGate publication ID224868779

P50authorAndré SchmidtQ73553936
Fredy R S GutierrezQ81419667
Paulo Marcos Matta GuedesQ90467214
P2093author name stringAnis Rassi
Gerson Jhonatan Rodrigues
João Santana Silva
Lusiane Maria Bendhack
Benedito Carlos Maciel
Grace Kelly Silva
Renata Dellalibera-Joviliano
José Antonio Marin Neto
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IL-23 and the Th17 pathway promote inflammation and impair antifungal immune resistanceQ58855387
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IL-17 and IL-22 are associated with protection against human kala azar caused by Leishmania donovaniQ24658015
The inhibitory cytokine IL-35 contributes to regulatory T-cell functionQ28258462
Interleukin-17 family members and inflammationQ28287876
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17Q29547855
Interleukin-2 signaling via STAT5 constrains T helper 17 cell generationQ29614840
IL-17 produced during Trypanosoma cruzi infection plays a central role in regulating parasite-induced myocarditisQ33532584
Role of Foxp3-positive regulatory T cells during infectionQ33737475
The role of the immune response on the development of severe clinical forms of human Chagas diseaseQ33839414
Regulatory T cells phenotype in different clinical forms of Chagas' diseaseQ33927456
Type 1 chemokine receptor expression in Chagas' disease correlates with morbidity in cardiac patients.Q34194841
CD4(+)CD25(+)Foxp3(+) regulatory T cells promote Th17 cells in vitro and enhance host resistance in mouse Candida albicans Th17 cell infection modelQ34627919
Chemokines, inflammation and Trypanosoma cruzi infection.Q34660986
IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonistQ35022575
Endogenous CD4(+) CD25(+) regulatory T cells have a limited role in the control of Trypanosoma cruzi infection in miceQ35689168
Regulatory T cells and infection: a dangerous necessityQ36975739
Human regulatory T cells: role in autoimmune disease and therapeutic opportunitiesQ37211296
Evidence that development of severe cardiomyopathy in human Chagas' disease is due to a Th1-specific immune responseQ39730057
Chagas disease: what is known and what is needed--a background articleQ40147985
Chronic Chagas' disease cardiomyopathy patients display an increased IFN-gamma response to Trypanosoma cruzi infection.Q40788068
Are increased frequency of macrophage-like and natural killer (NK) cells, together with high levels of NKT and CD4+CD25high T cells balancing activated CD8+ T cells, the key to control Chagas' disease morbidity?Q42497203
Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapyQ42971266
IL-17 is necessary for host protection against acute-phase Trypanosoma cruzi infectionQ43012403
Cyclic AMP decreases the production of NO and CCL2 by macrophages stimulated with Trypanosoma cruzi GPI-mucinsQ44055558
Experimental chemotherapy against Trypanosoma cruzi infection: essential role of endogenous interferon-gamma in mediating parasitologic cureQ44116597
Frequency of interferon- gamma -producing T cells specific for Trypanosoma cruzi inversely correlates with disease severity in chronic human Chagas diseaseQ44771953
The involvement of CD4+CD25+ T cells in the acute phase of Trypanosoma cruzi infection.Q45339719
Cutting edge: Foxp3+CD4+CD25+ regulatory T cells induced by IL-2 and TGF-beta are resistant to Th17 conversion by IL-6.Q45998381
Beneficial effects of benznidazole during an infectious-based situation of systemic inflammatory response: cecal ligation and puncture.Q46266746
Foxp3(+) regulatory T cells promote T helper 17 cell development in vivo through regulation of interleukin-2.Q46499482
Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10.Q47726082
IFN-gamma in human Chagas' disease: protection or pathology?Q47758411
Immunological imbalance between IFN-gamma and IL-10 levels in the sera of patients with the cardiac form of Chagas disease.Q51775764
Andean subregional Chagas disease area and the Andean initiative of Chagas disease.Q52684418
Characterization of cytokine production in murine Trypanosoma cruzi infection by in situ immunocytochemistry: lack of association between susceptibility and type 2 cytokine production.Q54154405
Potential role of CD4+CD25HIGH regulatory T cells in morbidity in Chagas diseaseQ56901414
Cytokine mRNA profile of peripheral blood mononuclear cells isolated from individuals with Trypanosoma cruzi chronic infectionQ58843253
Antibodies to Trypanosoma cruzi express idiotypic patterns that can differentiate between patients with asymptomatic or severe Chagas' diseaseQ58844351
The regulatory CD4+CD25+ T cells have a limited role on pathogenesis of infection with Trypanosoma cruziQ58844686
[Patients suffering dilated chagasic cardiopathy or non chagasic cardiopathy show an increased levels of tumor necrosis factor alpha]Q58845512
Chagasic patients with indeterminate clinical form of the disease have high frequencies of circulating CD3+CD16-CD56+ natural killer T cells and CD4+CD25High regulatory T lymphocytesQ58845519
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectChagas diseaseQ649558
cardiomyopathyQ847583
P304page(s)e1630
P577publication date2012-04-24
P1433published inPLoS Neglected Tropical DiseasesQ3359737
P1476titleDeficient regulatory T cell activity and low frequency of IL-17-producing T cells correlate with the extent of cardiomyopathy in human Chagas' disease
P478volume6

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