Deletion of the γ-aminobutyric acid transporter 2 (GAT2 and SLC6A13) gene in mice leads to changes in liver and brain taurine contents (scientific article)

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Glutamate uptake

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Taurine transport by rat hepatocytes in primary culture

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Localization of transporters using transporter-specific antibodies

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Specificity of antibodies: unexpected cross-reactivity of antibodies directed against the excitatory amino acid transporter 3 (EAAT3)

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Specificity controls for immunocytochemistry

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Tyrosine 140 of the gamma-aminobutyric acid transporter GAT-1 plays a critical role in neurotransmitter recognition

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GABA transporter heterogeneity: pharmacology and cellular localization

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Molecular characterization and in situ localization of a mouse retinal taurine transporter

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Cloning and expression of a rat brain GABA transporter

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Hepatic localisation of rat cysteine dioxygenase

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Cloning and expression of a high affinity taurine transporter from rat brain

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A highly efficient recombineering-based method for generating conditional knockout mutations

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Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters

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Neuronal, glial, and epithelial localization of gamma-aminobutyric acid transporter 2, a high-affinity gamma-aminobutyric acid plasma membrane transporter, in the cerebral cortex and neighboring structures

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Glial transporters for glutamate, glycine, and GABA: II. GABA transporters.

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Expression of a mouse brain cDNA encoding novel gamma-aminobutyric acid transporter

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The GABA transporter and its inhibitors

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New aspects of the blood-brain barrier transporters; its physiological roles in the central nervous system.

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GAT2/BGT-1 as a system responsible for the transport of gamma-aminobutyric acid at the mouse blood-brain barrier

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GABA's control of stem and cancer cell proliferation in adult neural and peripheral niches

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Deletion of the betaine-GABA transporter (BGT1; slc6a12) gene does not affect seizure thresholds of adult mice

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The betaine-GABA transporter (BGT1, slc6a12) is predominantly expressed in the liver and at lower levels in the kidneys and at the brain surface.

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Tiagabine, SK&F 89976-A, CI-966, and NNC-711 are selective for the cloned GABA transporter GAT-1.

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Taurine-induced long-lasting potentiation in the rat hippocampus shows a partial dissociation from total hippocampal taurine content and independence from activation of known taurine transporters

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Building biosynthetic schools: reviewing compartmentation of CNS taurine synthesis

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The rates of postmortem proteolysis of glutamate transporters differ dramatically between cells and between transporter subtypes

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Molecular characterization of four pharmacologically distinct gamma-aminobutyric acid transporters in mouse brain [corrected].

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Phenotype of the taurine transporter knockout mouse

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Neurotransmitter transporters expressed in glial cells as regulators of synapse function.

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Taurine in the central nervous system and the mammalian actions of taurine

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GABAA-receptor modification in taurine transporter knockout mice causes striatal disinhibition

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Function of taurine transporter (Slc6a6/TauT) as a GABA transporting protein and its relevance to GABA transport in rat retinal capillary endothelial cells

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Asymmetry of glia near central synapses favors presynaptically directed glutamate escape.

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Novel parent structures for inhibitors of the murine GABA transporters mGAT3 and mGAT4.

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Number, density, and surface/cytoplasmic distribution of GABA transporters at presynaptic structures of knock-in mice carrying GABA transporter subtype 1-green fluorescent protein fusions.

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Regulation of taurine transport at the blood-brain barrier by tumor necrosis factor-alpha, taurine and hypertonicity

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A Cre/loxP-deleter transgenic line in mouse strain 129S1/SvImJ.

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A gamma-aminobutyric acid-specific transport mechanism in mammalian kidney

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Impaired nuclear accumulation and shortened phosphorylation of ERK after growth factor stimulation in cultured hepatocytes from rats exposed to 2-acetylaminofluorene

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Characterization of tiagabine (NO-328), a new potent and selective GABA uptake inhibitor

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Cysteine metabolism in periportal and perivenous hepatocytes: perivenous cells have greater capacity for glutathione production and taurine synthesis but not for cysteine catabolism

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Postnatal development of high-affinity plasma membrane GABA transporters GAT-2 and GAT-3 in the rat cerebral cortex

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Taurine-induced long-lasting enhancement of synaptic transmission in mice: role of transporters

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Transmembrane domains I and II of the gamma-aminobutyric acid transporter GAT-4 contain molecular determinants of substrate specificity

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The brain-to-blood efflux transport of taurine and changes in the blood-brain barrier transport system by tumor necrosis factor-alpha

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GABA transporter deficiency causes tremor, ataxia, nervousness, and increased GABA-induced tonic conductance in cerebellum.

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Zonal distribution of cysteine uptake in the perfused rat liver

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Chronic liver disease is triggered by taurine transporter knockout in the mouse

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Renal cysts of inv/inv mice resemble early infantile nephronophthisis

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Taurine deficiency in the kitten: exchange and turnover of [35S] taurine in brain, retina, and other tissues

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Developmental expression of the neurotransmitter transporter GAT3.

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Interindividual differences in the levels of the glutamate transporters GLAST and GLT, but no clear correlation with Alzheimer's disease.

Q48286080

A monoclonal antibody raised against an [Na(+)+K+]coupled L-glutamate transporter purified from rat brain confirms glial cell localization.

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Sodium and chloride-dependent high and low-affinity uptakes of GABA by brain capillary endothelial cells.

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High-affinity GABA uptake and GABA-metabolizing enzymes in pig forebrain white matter: a quantitative study.

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Trafficking of amino acids between neurons and glia in vivo. Effects of inhibition of glial metabolism by fluoroacetate.

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GAT1 and GAT3 expression are differently localized in the human epileptogenic hippocampus.

Q48663917

Embryonic and postnatal expression of four gamma-aminobutyric acid transporter mRNAs in the mouse brain and leptomeninges.

Q48829268

Effects of chronic oral treatment with GABA-transaminase inhibitors on the GABA system in brain, liver, kidney, and plasma of the rat.

Q48863489

Na(+)-dependent transport of taurine is found only on the abluminal membrane of the blood-brain barrier.

Q50506979

Autoradiographic investigation of the distribution of [14C]GABA in tissues of normal and aminooxyacetic acid-treated mice

Q51162239

Transamination of gamma-aminobutyric acid and beta-alanine in brain and liver.

Q51348497

Heterogeneous distribution of glutamine synthetase during rat liver development.

Q52259269

Development of an (S)-1-{2-[Tris(4-methoxyphenyl)methoxy]ethyl}piperidine-3-carboxylic acid [(S)-SNAP-5114] Carba Analogue Inhibitor for Murine γ-Aminobutyric Acid Transporter Type 4

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Taurine transport across hepatocyte plasma membranes: analysis in isolated rat liver sinusoidal plasma membrane vesicles

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Uptake and catabolism of gamma-aminobutyric acid by the isolated perfused rat liver

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Colonic bacteria: a source of gamma-aminobutyric acid in blood

Q70163074

P433

issue

P407

language of work or name

English

Q1860

P921

main subject

Solute carrier family 6 (neurotransmitter transporter, GABA), member 13

Q21988054

P304

page(s)

35733-35746

P577

publication date

2012-08-15

P1433

published in

Journal of Biological Chemistry

Q867727

P1476

title

Deletion of the γ-aminobutyric acid transporter 2 (GAT2 and SLC6A13) gene in mice leads to changes in liver and brain taurine contents

P478

volume

287

Reverse relations

cites work (P2860)

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P356	DOI	10.1074/JBC.M112.368175
P932	PMC publication ID	3471754
P698	PubMed publication ID	22896705
P4011	Semantic Scholar paper ID	4d5e9dc664778b9c230f66fcefe82dc5845f62a3