Induced pluripotent stem cells: the new patient?

scientific article

Induced pluripotent stem cells: the new patient? is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1019616486
P356DOI10.1038/NRM3448
P698PubMed publication ID23034453
P5875ResearchGate publication ID232008928

P50authorFred GageQ895547
Milena BellinQ54478428
Maria C MarchettoQ91395511
Christine MummeryQ28842449
P2860cites workHuman engineered heart tissue as a versatile tool in basic research and preclinical toxicologyQ21134989
LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stressQ24294466
Mitochondrial Parkin recruitment is impaired in neurons derived from mutant PINK1 induced pluripotent stem cellsQ24300095
Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patientsQ24595997
Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cellsQ24617599
A map of human genome variation from population-scale sequencingQ24617794
Differentiation of human embryonic stem cells and induced pluripotent stem cells to cardiomyocytes: a methods overviewQ24618089
Modelling schizophrenia using human induced pluripotent stem cellsQ24633007
Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cellsQ24634829
Disease-specific induced pluripotent stem cellsQ24641981
Virus-free induction of pluripotency and subsequent excision of reprogramming factorsQ24644686
Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteinsQ24653753
An engineered cardiac reporter cell line identifies human embryonic stem cell-derived myocardial precursorsQ27438004
Induced pluripotent stem cell lines derived from human somatic cellsQ27860597
The International HapMap ProjectQ27860695
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factorsQ27860937
Induction of pluripotent stem cells from adult human fibroblasts by defined factorsQ27860967
Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA.Q28131663
A TALE nuclease architecture for efficient genome editingQ28301656
Generation of pluripotent stem cells from patients with type 1 diabetesQ37327472
Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs.Q37444336
Integration-free induced pluripotent stem cells derived from schizophrenia patients with a DISC1 mutationQ37734466
Cardiomyocyte differentiation of pluripotent stem cells and their use as cardiac disease modelsQ37832530
Methods for making induced pluripotent stem cells: reprogramming à la carteQ37845645
Strategies for homeostatic stem cell self-renewal in adult tissuesQ37887870
Pluripotent stem cell models of cardiac disease and their implication for drug discovery and developmentQ37894263
Diseases in a dish: modeling human genetic disorders using induced pluripotent cellsQ37965334
Neuronal properties, in vivo effects, and pathology of a Huntington's disease patient-derived induced pluripotent stem cellsQ38462208
Conversion of mouse and human fibroblasts into functional spinal motor neuronsQ38651033
Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells.Q38771932
Cardiomyocytes derived from pluripotent stem cells recapitulate electrophysiological characteristics of an overlap syndrome of cardiac sodium channel diseaseQ39339606
The first reported generation of several induced pluripotent stem cell lines from homozygous and heterozygous Huntington's disease patients demonstrates mutation related enhanced lysosomal activityQ39382468
Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutationsQ39506695
Disease characterization using LQTS-specific induced pluripotent stem cellsQ39595974
Complete genetic correction of ips cells from Duchenne muscular dystrophyQ39641162
Neuregulin/ErbB signaling regulates cardiac subtype specification in differentiating human embryonic stem cellsQ39673715
Generation of human embryonic stem cell reporter lines expressing GFP specifically in neural progenitorsQ39699814
Rescue of ATP7B function in hepatocyte-like cells from Wilson's disease induced pluripotent stem cells using gene therapy or the chaperone drug curcuminQ39748845
Prediction of drug-induced cardiotoxicity using human embryonic stem cell-derived cardiomyocytesQ39759039
Non-cell-autonomous effect of human SOD1 G37R astrocytes on motor neurons derived from human embryonic stem cellsQ39910905
Chemically defined medium supporting cardiomyocyte differentiation of human embryonic stem cellsQ39971906
Marked differences in differentiation propensity among human embryonic stem cell linesQ40012772
A method for genetic modification of human embryonic stem cells using electroporationQ40143374
Identification and selection of cardiomyocytes during human embryonic stem cell differentiationQ40145603
Differentiation of human embryonic stem cells to cardiomyocytes: role of coculture with visceral endoderm-like cellsQ40648427
Preparation of uniaxial multichannel silk fibroin scaffolds for guiding primary neurons.Q42013709
IGF1 as a Potential Treatment for Rett Syndrome: Safety Assessment in Six Rett PatientsQ42049161
Generation of transgene-free lung disease-specific human induced pluripotent stem cells using a single excisable lentiviral stem cell cassette.Q42118625
A targeted NKX2.1 human embryonic stem cell reporter line enables identification of human basal forebrain derivatives.Q42485666
Isolation of human iPS cells using EOS lentiviral vectors to select for pluripotencyQ42811272
Restricted ethnic diversity in human embryonic stem cell linesQ42812882
Generation of liver disease-specific induced pluripotent stem cells along with efficient differentiation to functional hepatocyte-like cellsQ42814864
A human iPSC model of Hutchinson Gilford Progeria reveals vascular smooth muscle and mesenchymal stem cell defectsQ42815540
Induced pluripotent stem cell models from X-linked adrenoleukodystrophy patientsQ42817044
Modeling familial Alzheimer's disease with induced pluripotent stem cellsQ42817521
Human Pompe disease-induced pluripotent stem cells for pathogenesis modeling, drug testing and disease marker identificationQ42817633
Excitation-induced ataxin-3 aggregation in neurons from patients with Machado-Joseph diseaseQ42818202
Drug screening for ALS using patient-specific induced pluripotent stem cellsQ42820289
Vitamin C enhances the generation of mouse and human induced pluripotent stem cellsQ43207059
Developmental changes in contractility and sarcomeric proteins from the early embryonic to the adult stage in the mouse heartQ44364053
2011 FDA drug approvalsQ44973933
Development of patient-specific neurons in schizophrenia using induced pluripotent stem cellsQ47788549
Altered oxygen metabolism associated to neurogenesis of induced pluripotent stem cells derived from a schizophrenic patientQ48860052
Modeling neuronal defects associated with a lysosomal disorder using patient-derived induced pluripotent stem cells.Q49153656
CDKL5 ensures excitatory synapse stability by reinforcing NGL-1-PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons.Q50305506
Generation of patient-specific induced pluripotent stem cell-derived cardiomyocytes as a cellular model of arrhythmogenic right ventricular cardiomyopathy.Q50506853
NKX2-5(eGFP/w) hESCs for isolation of human cardiac progenitors and cardiomyocytes.Q50509476
Meta-analysis of the heterogeneity of X chromosome inactivation in human pluripotent stem cells.Q51511217
Kinetin in familial dysautonomia carriers: implications for a new therapeutic strategy targeting mRNA splicing.Q54785499
The dark side of induced pluripotencyQ59048452
High-resolution DNA analysis of human embryonic stem cell lines reveals culture-induced copy number changes and loss of heterozygosityQ59696431
Stem cells. Diseases in a dish take offQ82616931
Induced pluripotent stem cells--a cautionary noteQ84242212
Repolarization reserve determines drug responses in human pluripotent stem cell derived cardiomyocytesQ85250707
Erosion of dosage compensation impacts human iPSC disease modelingQ36703082
In vitro modeling of ryanodine receptor 2 dysfunction using human induced pluripotent stem cellsQ37005193
SIRPA is a specific cell-surface marker for isolating cardiomyocytes derived from human pluripotent stem cells.Q37104201
Reprogramming of human primary somatic cells by OCT4 and chemical compoundsQ37267824
Cardiomyocytes generated from CPVTD307H patients are arrhythmogenic in response to β-adrenergic stimulationQ37294805
Characterization of Human Huntington's Disease Cell Model from Induced Pluripotent Stem CellsQ28475963
Modeling retinal degeneration using patient-specific induced pluripotent stem cellsQ28477132
Isogenic pairs of wild type and mutant induced pluripotent stem cell (iPSC) lines from Rett syndrome patients as in vitro disease modelQ28477225
Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factorsQ28749672
Human induced pluripotent stem cells free of vector and transgene sequencesQ29547624
Induced pluripotent stem cells from a spinal muscular atrophy patientQ29614340
Induced pluripotent stem cells generated without viral integrationQ29614343
Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's diseaseQ29615682
Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cellsQ29615870
Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neuronsQ29616199
Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived populationQ29616533
Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genomeQ29616636
Somatic coding mutations in human induced pluripotent stem cellsQ29616798
Pre-mRNA splicing and human diseaseQ29617335
Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic developmentQ29617978
Generation of induced pluripotent stem cells using recombinant proteinsQ29619162
A Model for Neural Development and Treatment of Rett Syndrome Using Human Induced Pluripotent Stem CellsQ29619964
Modelling the long QT syndrome with induced pluripotent stem cellsQ29620092
Patient-specific induced pluripotent stem-cell models for long-QT syndromeQ29620353
Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat heartsQ29620480
Development of functional human embryonic stem cell-derived neurons in mouse brainQ30476562
Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndromeQ30499663
Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndromeQ30529349
Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy.Q30539904
Human cerebral cortex development from pluripotent stem cells to functional excitatory synapsesQ30562410
Transcriptional signature and memory retention of human-induced pluripotent stem cellsQ33504601
Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disordersQ33560423
Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells.Q33672762
Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potencyQ33732735
Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndromeQ33910479
Engineering of human pluripotent stem cells by AAV-mediated gene targetingQ33930075
Reprogramming of mouse and human cells to pluripotency using mature microRNAs.Q34027071
Transgene-free production of pluripotent stem cells using piggyBac transposonsQ34028014
Transgene excision has no impact on in vivo integration of human iPS derived neural precursorsQ34035837
Concise review: the promise of human induced pluripotent stem cell-based studies of schizophreniaQ34051160
Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian ratsQ34115609
Induced pluripotent stem cells from individuals with recessive dystrophic epidermolysis bullosaQ34120479
Genetic correction and analysis of induced pluripotent stem cells from a patient with gyrate atrophy.Q34175757
Harnessing the potential of induced pluripotent stem cells for regenerative medicineQ34182222
Induced pluripotency: history, mechanisms, and applicationsQ34206028
High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents.Q34213428
Production of de novo cardiomyocytes: human pluripotent stem cell differentiation and direct reprogrammingQ34245487
The promise of induced pluripotent stem cells in research and therapyQ34248218
Diagnosing the decline in pharmaceutical R&D efficiencyQ34257771
Efficient generation of functional dopaminergic neurons from human induced pluripotent stem cells under defined conditionsQ34373911
Hematopoietic differentiation of induced pluripotent stem cells from patients with mucopolysaccharidosis type I (Hurler syndrome)Q34557967
L1 retrotransposition in neurons is modulated by MeCP2Q34686579
Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell linesQ34714112
Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutationQ34793218
Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndromeQ34930935
Isolation of MECP2-null Rett Syndrome patient hiPS cells and isogenic controls through X-chromosome inactivationQ34955419
Generation of keratinocytes from normal and recessive dystrophic epidermolysis bullosa-induced pluripotent stem cells.Q35008203
Oxidase-deficient neutrophils from X-linked chronic granulomatous disease iPS cells: functional correction by zinc finger nuclease-mediated safe harbor targetingQ35030912
Generation of induced pluripotent stem cell lines from 3 distinct laminopathies bearing heterogeneous mutations in lamin A/CQ35052074
Downregulation of VAPB expression in motor neurons derived from induced pluripotent stem cells of ALS8 patientsQ35175041
Kinetin improves IKBKAP mRNA splicing in patients with familial dysautonomiaQ35291933
Specification of neuronal and glial subtypes from human pluripotent stem cellsQ35501624
Nanowired three-dimensional cardiac patchesQ35528919
A functionally characterized test set of human induced pluripotent stem cellsQ35588556
Nuclear plakoglobin is essential for differentiation of cardiac progenitor cells to adipocytes in arrhythmogenic right ventricular cardiomyopathyQ35612944
Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locusQ35692589
Generation of human vascular smooth muscle subtypes provides insight into embryological origin-dependent disease susceptibilityQ35737818
Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell cultureQ35794574
Survival and differentiation of transplanted neural stem cells derived from human induced pluripotent stem cells in a rat stroke modelQ35809643
Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerabilityQ35889309
Background mutations in parental cells account for most of the genetic heterogeneity of induced pluripotent stem cellsQ35947171
Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cellsQ35966957
Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardiaQ36037969
Signaling defects in iPSC-derived fragile X premutation neuronsQ36142068
Evidence for premature aging due to oxidative stress in iPSCs from Cockayne syndromeQ36142076
Targeted gene correction of laminopathy-associated LMNA mutations in patient-specific iPSCsQ36345932
P433issue11
P921main subjectpatientQ181600
P304page(s)713-726
P577publication date2012-10-04
P1433published inNature Reviews Molecular Cell BiologyQ1573120
P1476titleInduced pluripotent stem cells: the new patient?
P478volume13

Reverse relations

cites work (P2860)
Q904619023D Bioprinted Human Cortical Neural Constructs Derived from Induced Pluripotent Stem Cells
Q917866223D Cardiac Cell Culture: A Critical Review of Current Technologies and Applications
Q337301543D In vitro model of a functional epidermal permeability barrier from human embryonic stem cells and induced pluripotent stem cells
Q50329951A Comprehensive Atlas of E3 Ubiquitin Ligase Mutations in Neurological Disorders
Q35999782A Perspective on Studying G-Protein-Coupled Receptor Signaling with Resonance Energy Transfer Biosensors in Living Organisms
Q36740391A Role for the Transcription Factor Nk2 Homeobox 1 in Schizophrenia: Convergent Evidence from Animal and Human Studies
Q37228986A new hERG allosteric modulator rescues genetic and drug-induced long-QT syndrome phenotypes in cardiomyocytes from isogenic pairs of patient induced pluripotent stem cells
Q33768227A novel mutation in LRSAM1 causes axonal Charcot-Marie-Tooth disease with dominant inheritance
Q38573829A retrospective review of the progress in amyotrophic lateral sclerosis drug discovery over the last decade and a look at the latest strategies
Q39380660A simple method for deriving functional MSCs and applied for osteogenesis in 3D scaffolds.
Q57048812A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation
Q50518321ALPK3-deficient cardiomyocytes generated from patient-derived induced pluripotent stem cells and mutant human embryonic stem cells display abnormal calcium handling and establish that ALPK3 deficiency underlies familial cardiomyopathy.
Q33946049Abnormal oxidative stress responses in fibroblasts from preeclampsia infants
Q33737156Adult hair follicle stem cells do not retain the older DNA strands in vivo during normal tissue homeostasis
Q38437316Advanced Strategies for End-Stage Heart Failure: Combining Regenerative Approaches with LVAD, a New Horizon?
Q52606323Advanced maturation of human cardiac tissue grown from pluripotent stem cells.
Q40786353All-optical control of cardiac excitation: combined high-resolution optogenetic actuation and optical mapping
Q35595728Autism spectrum disorders: emerging mechanisms and mechanism-based treatment.
Q38642565Back and forth in time: Directing age in iPSC-derived lineages.
Q38300878Bacterial-induced cell reprogramming to stem cell-like cells: new premise in host-pathogen interactions
Q30358385Biology-inspired microphysiological system approaches to solve the prediction dilemma of substance testing
Q46303600Blood-brain barrier-on-a-chip: Microphysiological systems that capture the complexity of the blood-central nervous system interface
Q101216809BrainPhys neuronal medium optimized for imaging and optogenetics in vitro
Q30354544Bridging the gap between genetic associations and molecular mechanisms for type 2 diabetes.
Q40453067Capturing the biology of disease severity in a PSC-based model of familial dysautonomia
Q28079057Cardiac Regenerative Medicine: The Potential of a New Generation of Stem Cells
Q38393181Cardiac disease modeling using induced pluripotent stem cell-derived human cardiomyocytes
Q21195758Cardiac regeneration and diabetes
Q34534994Cell fusion enhances mesendodermal differentiation of human induced pluripotent stem cells
Q48143410Comparative transcriptomics of hepatic differentiation of human pluripotent stem cells and adult human liver tissue.
Q36958208Complexity of dopamine metabolism.
Q56879461Comprehensive comparative analysis of 5'-end RNA-sequencing methods
Q28080945Concise Review: Induced Pluripotent Stem Cells as New Model Systems in Oncology
Q38850545Concise Review: Measuring Physiological Responses of Human Pluripotent Stem Cell Derived Cardiomyocytes to Drugs and Disease
Q28649438Concise review: modeling multiple sclerosis with stem cell biological platforms: toward functional validation of cellular and molecular phenotypes in inflammation-induced neurodegeneration
Q41788686Convergent functional genomics of stem cell-derived cells
Q38997127Coordinated Proliferation and Differentiation of Human-Induced Pluripotent Stem Cell-Derived Cardiac Progenitor Cells Depend on Bone Morphogenetic Protein Signaling Regulation by GREMLIN 2.
Q55260762Current state of therapeutic development for rare cancers in Japan, and proposals for improvement.
Q39301532Deep intronic mutations and human disease
Q37017090Derivation of Diverse Hormone-Releasing Pituitary Cells from Human Pluripotent Stem Cells.
Q38257522Design strategies of biodegradable scaffolds for tissue regeneration
Q30428895Diabetes-associated macrovascular complications: cell-based therapy a new tool?
Q40311122Differentiation of human and murine induced pluripotent stem cells to microglia-like cells
Q58734825Differentiation of human iPSCs into functional podocytes
Q38911795Differentiation of human pluripotent stem cells into Medial Ganglionic Eminence vs. Caudal Ganglionic Eminence cells
Q38883549Differentiation of neuroepithelial stem cells into functional dopaminergic neurons in 3D microfluidic cell culture
Q37619231Disease models for the development of therapies for lysosomal storage diseases
Q52975832Dynamic Variations in Genetic Integrity Accompany Changes in Cell Fate.
Q35665070Effectiveness of gene delivery systems for pluripotent and differentiated cells.
Q40982138Efficient CRISPR-Cas9-mediated generation of knockin human pluripotent stem cells lacking undesired mutations at the targeted locus
Q35010413Efficient production of retroviruses using PLGA/bPEI-DNA nanoparticles and application for reprogramming somatic cells
Q38440243Efficient specification of interneurons from human pluripotent stem cells by dorsoventral and rostrocaudal modulation.
Q42060920Electronic "expression" of the inward rectifier in cardiocytes derived from human-induced pluripotent stem cells
Q38750884Electrophysiological Analysis of human Pluripotent Stem Cell-derived Cardiomyocytes (hPSC-CMs) Using Multi-electrode Arrays (MEAs)
Q47207619Engineered Microenvironments for Maturation of Stem Cell Derived Cardiac Myocytes
Q38378499Engineering Stem Cells for Biomedical Applications.
Q58556060Epigenetic Control of Endocrine Pancreas Differentiation : Current Knowledge and Future Perspectives
Q35699296Epigenetic changes in the developing brain: Effects on behavior
Q35180607Epigenetic therapy for Friedreich ataxia
Q26781319Excitation-contraction coupling of human induced pluripotent stem cell-derived cardiomyocytes
Q91678555Expanding the editable genome and CRISPR-Cas9 versatility using DNA cutting-free gene targeting based on in trans paired nicking
Q38207606Familial Alzheimer's disease modelling using induced pluripotent stem cell technology
Q91802461Fast and Efficient Neural Conversion of Human Hematopoietic Cells
Q34684538Fast and efficient neural conversion of human hematopoietic cells
Q39060361Forced aggregation and defined factors allow highly uniform-sized embryoid bodies and functional cardiomyocytes from human embryonic and induced pluripotent stem cells.
Q37592348Functional roles of Nurr1, Pitx3, and Lmx1a in neurogenesis and phenotype specification of dopamine neurons during in vitro differentiation of embryonic stem cells
Q26849397Functions of heterogeneous nuclear ribonucleoproteins in stem cell potency and differentiation
Q33552001Gene profiling of human induced pluripotent stem cell-derived astrocyte progenitors following spinal cord engraftment
Q27333621Generation and characterization of functional cardiomyocytes derived from human T cell-derived induced pluripotent stem cells
Q27301480Generation of Functional Cardiomyocytes from Efficiently Generated Human iPSCs and a Novel Method of Measuring Contractility
Q35162006Generation of induced pluripotent stem cells from muscular dystrophy patients: efficient integration-free reprogramming of urine derived cells
Q28544903Genetic heterogeneity of induced pluripotent stem cells: results from 24 clones derived from a single C57BL/6 mouse
Q92823561Genetic variation in GNB5 causes bradycardia by augmenting the cholinergic response via increased acetylcholine-activated potassium current (I K,ACh)
Q26996283Getting to the heart of the matter: long non-coding RNAs in cardiac development and disease
Q44315676Gorlin syndrome-derived induced pluripotent stem cells are hypersensitive to hedgehog-mediated osteogenic induction
Q40637296Human Neuropsychiatric Disease Modeling using Conditional Deletion Reveals Synaptic Transmission Defects Caused by Heterozygous Mutations in NRXN1.
Q97529091Human forebrain endothelial cell therapy for psychiatric disorders
Q39345477Human heart disease: lessons from human pluripotent stem cell-derived cardiomyocytes.
Q41609643Human iPS cell models of Jervell and Lange-Nielsen syndrome
Q41868474Human iPSC-based modeling of late-onset disease via progerin-induced aging
Q55194774Human iPSC-based models highlight defective glial and neuronal differentiation from neural progenitor cells in metachromatic leukodystrophy.
Q38643034Human induced pluripotent stem cells as a research tool in Alzheimer's disease
Q41664792Human pluripotent stem cell models of cardiac disease: from mechanisms to therapies
Q90599546Hydroxyurea Facilitates Manifestation of Disease Relevant Phenotypes in Patients-Derived IPSCs-Based Modeling of Late-Onset Parkinson's Disease
Q38136473In vivo reprogramming in inflammatory bowel disease
Q38559734Induced Pluripotent Stem Cells Derived from Alzheimer's Disease Patients: The Promise, the Hope and the Path Ahead.
Q38116769Induced Pluripotent Stem Cells and Disorders of the Nervous System: Progress, Problems, and Prospects
Q38242113Induced Pluripotent Stem Cells for Disease Modeling and Drug Discovery in Neurodegenerative Diseases
Q38104143Induced pluripotent stem cells as a new strategy for cardiac regeneration and disease modeling
Q38218254Induced pluripotent stem cells for regenerative medicine
Q26749360Induced pluripotent stem cells in Alzheimer's disease: applications for disease modeling and cell-replacement therapy
Q34036938Induced pluripotent stem cells in medicine and biology
Q92512243Induced pluripotent stem cells, a giant leap for mankind therapeutic applications
Q28079217Inherited heart disease - what can we expect from the second decade of human iPS cell research?
Q38819976Integrating cardiomyocytes from human pluripotent stem cells in safety pharmacology: has the time come?
Q38182329Integrating the roles of long and small non-coding RNA in brain function and disease
Q90482640Intensive care for human hearts in pluripotent stem cell models
Q38130450Is aging a barrier to reprogramming? Lessons from induced pluripotent stem cells
Q34038853Isogenic human pluripotent stem cell pairs reveal the role of a KCNH2 mutation in long-QT syndrome
Q35781992Large-Scale Nanoelectrode Arrays to Monitor the Dopaminergic Differentiation of Human Neural Stem Cells
Q28829869Large-Scale Production of Mature Neurons from Human Pluripotent Stem Cells in a Three-Dimensional Suspension Culture System
Q36239384Lessons from Toxicology: Developing a 21st-Century Paradigm for Medical Research
Q50210670Low-Density Neuronal Cultures from Human Induced Pluripotent Stem Cells
Q64075653MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo
Q47241525MUSCLEMOTION: A Versatile Open Software Tool to Quantify Cardiomyocyte and Cardiac Muscle Contraction In Vitro and In Vivo.
Q34153953Measuring the contractile forces of human induced pluripotent stem cell-derived cardiomyocytes with arrays of microposts
Q26852506Mending broken hearts: cardiac development as a basis for adult heart regeneration and repair
Q34341540MiRiad Roles for MicroRNAs in Cardiac Development and Regeneration
Q26747691Microfluidic organ-on-chip technology for blood-brain barrier research
Q36600856Micropost arrays for measuring stem cell-derived cardiomyocyte contractility
Q89741244Migration, Chemo-Attraction, and Co-Culture Assays for Human Stem Cell-Derived Endothelial Cells and GABAergic Neurons
Q26748486Modeling Barrier Tissues In Vitro: Methods, Achievements, and Challenges
Q26799933Modeling Viral Infectious Diseases and Development of Antiviral Therapies Using Human Induced Pluripotent Stem Cell-Derived Systems
Q34540416Modeling a genetic risk for schizophrenia in iPSCs and mice reveals neural stem cell deficits associated with adherens junctions and polarity
Q35056065Modeling human neurological disorders with induced pluripotent stem cells
Q39130188Modeling neurodevelopmental and psychiatric diseases with human iPSCs
Q51043236Modelling IRF8 Deficient Human Hematopoiesis and Dendritic Cell Development with Engineered iPS Cells.
Q37609839Molecular dissection of germline chromothripsis in a developmental context using patient-derived iPS cells
Q38248400Molecular networks and the evolution of human cognitive specializations
Q33861723Monitoring the differentiation and migration patterns of neural cells derived from human embryonic stem cells using a microfluidic culture system.
Q37622098Multiple Roles of MYC in Integrating Regulatory Networks of Pluripotent Stem Cells.
Q40884175Neural progenitors derived from human induced pluripotent stem cells survive and differentiate upon transplantation into a rat model of amyotrophic lateral sclerosis
Q38110960Neural stem cells as tools for drug discovery: novel platforms and approaches
Q35644670Neuronal medium that supports basic synaptic functions and activity of human neurons in vitro
Q36568097Neuropeptidomics Mass Spectrometry Reveals Signaling Networks Generated by Distinct Protease Pathways in Human Systems
Q26995562New opportunities: harnessing induced pluripotency for discovery in diabetes and metabolism
Q38986478On the shoulders of Hubrecht: From embryos to stem cells
Q37617276One-Step Seeding of Neural Stem Cells with Vitronectin-Supplemented Medium for High-Throughput Screening Assays
Q63246542Opportunities and challenges for the use of induced pluripotent stem cells in modelling neurodegenerative disease
Q34353458Opportunities and challenges of pluripotent stem cell neurodegenerative disease models
Q47822920Optical Method to Quantify Mechanical Contraction and Calcium Transients of Human Pluripotent Stem Cell-Derived Cardiomyocytes.
Q27317028OptoDyCE as an automated system for high-throughput all-optical dynamic cardiac electrophysiology.
Q38905001Organ-on-a-Chip Systems: Microengineering to Biomimic Living Systems
Q38195304Organs-on-a-chip: a new tool for drug discovery
Q37693830Origins and implications of pluripotent stem cell variability and heterogeneity
Q37337917Parkin and PINK1 Patient iPSC-Derived Midbrain Dopamine Neurons Exhibit Mitochondrial Dysfunction and α-Synuclein Accumulation
Q35600964Parkin mutations reduce the complexity of neuronal processes in iPSC-derived human neurons
Q51389361Patient iPSCs: a new discovery tool for Smith-Lemli-Opitz syndrome.
Q39144910Perspectives and Challenges of Pluripotent Stem Cells in Cardiac Arrhythmia Research.
Q42962438Pluripotent and somatic stem cells: from basic science to utilization in disease modeling and therapeutic application. Meeting report on the 7th International Meeting of the Stem Cell Network North Rhine Westphalia.
Q37121491Pluripotent stem cells as a model to study non-coding RNAs function in human neurogenesis
Q38714328Pluripotent stem cells in disease modelling and drug discovery
Q26999292Pluripotent stem cells in regenerative medicine: challenges and recent progress
Q37351739Predicting the functional states of human iPSC-derived neurons with single-cell RNA-seq and electrophysiology
Q28082747Present and future challenges of induced pluripotent stem cells
Q27008903Programming and Reprogramming Cellular Age in the Era of Induced Pluripotency
Q26776053Prospects and Challenges of Induced Pluripotent Stem Cells in Equine Health
Q40090286RNAseq analysis for the diagnosis of muscular dystrophy
Q37414577Rapamycin regulates autophagy and cell adhesion in induced pluripotent stem cells.
Q41573786Real-Time Force and Frequency Analysis of Engineered Human Heart Tissue Derived from Induced Pluripotent Stem Cells Using Magnetic Sensing.
Q34752070Recessive cardiac phenotypes in induced pluripotent stem cell models of Jervell and Lange-Nielsen syndrome: disease mechanisms and pharmacological rescue
Q99589769Reprogramming Urine-Derived Cells using Commercially Available Self-Replicative RNA and a Single Electroporation
Q26853155Reprogramming cells with synthetic proteins
Q28544716Reprogramming of HUVECs into induced pluripotent stem cells (HiPSCs), generation and characterization of HiPSC-derived neurons and astrocytes
Q38482062Role of adult hippocampal neurogenesis in cognition in physiology and disease: pharmacological targets and biomarkers
Q37653706Role of heme oxygenase-1 in postnatal differentiation of stem cells: a possible cross-talk with microRNAs
Q52855874Scalable Expansion of Pluripotent Stem Cells.
Q30251961Schizophrenia.
Q34511100Selective development of myogenic mesenchymal cells from human embryonic and induced pluripotent stem cells
Q38216498Self-renewal and cell lineage differentiation strategies in human embryonic stem cells and induced pluripotent stem cells.
Q91991322Social Isolation Rearing Induces Neuropsychiatric Diseases: Updated Overview
Q90229721Stem cell-based Lung-on-Chips: The best of both worlds?
Q47559391Stem cells: from biomedical research towards clinical applications.
Q45205312Subtype-specific promoter-driven action potential imaging for precise disease modelling and drug testing in hiPSC-derived cardiomyocytes
Q87681974TGF-β Signaling in Control of Cardiovascular Function
Q34428986The Autism Spectrum Disorders Stem Cell Resource at Children's Hospital of Orange County: Implications for Disease Modeling and Drug Discovery
Q92815378The Emergence of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes (hiPSC-CMs) as a Platform to Model Arrhythmogenic Diseases
Q39042193The Sustained Impact of Model Organisms-in Genetics and Epigenetics
Q34386434The aging signature: a hallmark of induced pluripotent stem cells?
Q38663718The ascendance of microphysiological systems to solve the drug testing dilemma
Q35765543The current status of iPS cells in cardiac research and their potential for tissue engineering and regenerative medicine
Q58577684The effect of rho kinase inhibition on morphological and electrophysiological maturity in iPSC-derived neurons
Q38109499The potential of stem cell research for the treatment of neuronal damage in glaucoma.
Q38834532The use of human adipose-derived stem cells based cytotoxicity assay for acute toxicity test.
Q39413537Three-dimensional co-cultures of human endothelial cells and embryonic stem cell-derived pericytes inside a microfluidic device
Q89107012Tissue engineered bone mimetics to study bone disorders ex vivo: Role of bioinspired materials
Q38174727Tissue engineering for plastic surgeons: a primer
Q53479362Translational strategies and challenges in regenerative medicine.
Q35009852Two miRNA clusters reveal alternative paths in late-stage reprogramming
Q47705950Use of a neonatal rat system as a bioincubator to generate adult-like mature cardiomyocytes from human and mouse pluripotent stem cells.
Q35020639Use of cartilage derived from murine induced pluripotent stem cells for osteoarthritis drug screening.
Q36357156Using human induced pluripotent stem cells to model cerebellar disease: hope and hype.
Q39873476Using induced human pluripotent stem cells to study Diamond-Blackfan anemia: an outlook on the clinical possibilities.
Q34143269Using physiologically-based pharmacokinetic-guided "body-on-a-chip" systems to predict mammalian response to drug and chemical exposure
Q42671611Variability of Action Potentials Within and Among Cardiac Cell Clusters Derived from Human Embryonic Stem Cells
Q37131089Will brain cells derived from induced pluripotent stem cells or directly converted from somatic cells (iNs) be useful for schizophrenia research?
Q43601153Workshop meeting report Organs-on-Chips: human disease models
Q41947844hiPS-MSCs differentiation towards fibroblasts on a 3D ECM mimicking scaffold

Search more.