Organization of the G protein-coupled receptors rhodopsin and opsin in native membranes

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Organization of the G protein-coupled receptors rhodopsin and opsin in native membranes is …
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scholarly articleQ13442814

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P356DOI10.1074/JBC.M302536200
P932PMC publication ID1360145
P698PubMed publication ID12663652

P50authorKrzysztof PalczewskiQ6440188
Slawomir FilipekQ44340544
P2093author name stringAndreas Engel
Yan Liang
Dimitrios Fotiadis
David A Saperstein
P2860cites workRetinopathy induced in mice by targeted disruption of the rhodopsin geneQ73040800
Visual arrestin activity may be regulated by self-associationQ78010480
Responses of retinal rods to single photonsQ24537450
Crystal structure of rhodopsin: A G protein-coupled receptorQ27625972
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Functional role of internal water molecules in rhodopsin revealed by X-ray crystallography.Q27638895
X-ray crystal structure of arrestin from bovine rod outer segmentsQ27748911
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Purification and characterization of rhodopsin kinaseQ28281417
A Method to Identify Protein Sequences That Fold into a Known Three-Dimensional StructureQ28282741
Rhodopsin-transducin interface: studies with conformationally constrained peptidesQ28365146
Evaluation of comparative protein modeling by MODELLERQ29617322
Seven-transmembrane receptorsQ29619896
Kinetic analysis of the activation of transducin by photoexcited rhodopsin. Influence of the lateral diffusion of transducin and competition of guanosine diphosphate and guanosine triphosphate for the nucleotide siteQ33192161
Projection structure of frog rhodopsin in two crystal formsQ33708383
The height of biomolecules measured with the atomic force microscope depends on electrostatic interactions.Q33907468
Oligomerization of G-protein-coupled transmitter receptors.Q34205602
Activation of rhodopsin: new insights from structural and biochemical studiesQ34245445
TAUTOMERIC FORMS OF METARHODOPSIN.Q34255832
Confronting complexity: the interlink of phototransduction and retinoid metabolism in the vertebrate retinaQ34272304
Crystal structure of rhodopsin: implications for vision and beyondQ34331469
Peptide interactions with G-protein coupled receptorsQ34483031
G protein-coupled receptor rhodopsin: a prospectusQ34537340
The genetic control of eye development and its implications for the evolution of the various eye-typesQ34570183
G-protein-coupled receptor dimerization: modulation of receptor function.Q34578524
Morphological, physiological, and biochemical changes in rhodopsin knockout miceQ34853562
G-protein-coupled receptor oligomerization and its potential for drug discoveryQ34932201
G protein-coupled receptor drug discovery: implications from the crystal structure of rhodopsin.Q35162044
Beta-arrestin and arrestin are recognized by autoantibodies in sera from multiple sclerosis patientsQ36232654
Two-dimensional rhodopsin crystals from disk membranes of frog retinal rod outer segmentsQ36282096
Electron microscope and low-angle X-ray diffraction studies on outer segment membranes from the retina of the frogQ36578209
Surface topographies at subnanometer-resolution reveal asymmetry and sidedness of aquaporin-1.Q36842694
Rapid restoration of visual pigment and function with oral retinoid in a mouse model of childhood blindnessQ37236123
The structure of bacteriorhodopsin and its relevance to the visual opsins and other seven-helix G-protein coupled receptorsQ37586615
Molecular design of an amplification cascade in visionQ39493593
The molecular mechanism of visual excitation and its relation to the structure and composition of the rod outer segmentQ39508425
Reconstitution of the vertebrate visual cascade using recombinant heterotrimeric transducin purified from Sf9 cellsQ40840921
High resolution AFM topographs of the Escherichia coli water channel aquaporin Z.Q42681039
Light- and guanosine 5'-3-O-(thio)triphosphate-sensitive localization of a G protein and its effector on detergent-resistant membrane rafts in rod photoreceptor outer segmentsQ43586300
Signal-dependent translocation of transducin, RGS9-1-Gbeta5L complex, and arrestin to detergent-resistant membrane rafts in photoreceptorsQ43907940
The fourth transmembrane segment forms the interface of the dopamine D2 receptor homodimer.Q44259028
Planar liquid-like arrangement of photopigment molecules in frog retinal receptor disk membranesQ45058924
Photoreceptor membrane proteins, phototransduction, and retinal degenerative diseases. The Friedenwald Lecture.Q48379977
Two-dimensional crystallization of bovine rhodopsin.Q48540463
Rpe65 is necessary for production of 11-cis-vitamin A in the retinal visual cycle.Q52532886
Allosteric behavior in transducin activation mediated by rhodopsin. Initial rate analysis of guanine nucleotide exchange.Q52601083
Dimerization of G-protein-coupled receptors.Q53676491
The eyes of deep-sea fish. II. Functional morphology of the retinaQ57088210
Rhodopsin dimers in native disc membranesQ59056014
Neutron diffraction studies of retinal rod outer segment membranesQ59064825
Neutron diffraction analysis of the structure of retinal photoreceptor membranes and rhodopsinQ67809274
Evidence against the role of rhodopsin in rod outer segment binding to RPE cellsQ68268099
Rotational Diffusion of Rhodopsin in the Visual Receptor MembraneQ69091767
Lateral Diffusion of Visual Pigment in Photoreceptor Disk MembranesQ69136395
Anti-rhodopsin monoclonal antibodies of defined specificity: characterization and applicationQ70122085
Protein complement of rod outer segments of frog retinaQ70150246
Lateral diffusion of visual pigment in rod disk membranesQ70409979
Localization of binding sites for carboxyl terminal specific anti-rhodopsin monoclonal antibodies using synthetic peptidesQ70764425
Semper: Distortion Compensation, Selective Averaging, 3-D Reconstruction, and Transfer Function Correction in a Highly Programmable SystemQ71545226
Rod outer segment retinol dehydrogenase: substrate specificity and role in phototransductionQ72773568
P433issue24
P407language of work or nameEnglishQ1860
P921main subjectG protein-coupled receptorQ38173
P304page(s)21655-21662
P577publication date2003-03-27
P1433published inJournal of Biological ChemistryQ867727
P1476titleOrganization of the G protein-coupled receptors rhodopsin and opsin in native membranes
P478volume278

Reverse relations

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Q57364538The Photoreceptor Membrane as a Model System in the Study of Biological Signal Transduction
Q57952195The Retinitis Pigmentosa-Linked Mutations in Transmembrane Helix 5 of Rhodopsin Disrupt Cellular Trafficking Regardless of Oligomerization State
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