Low Temperature Dynamic Mapping Reveals Unexpected Order and Disorder in Troponin

scientific article published on October 2, 2010

Low Temperature Dynamic Mapping Reveals Unexpected Order and Disorder in Troponin is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.M110.181305
P953full work available at URLhttp://www.jbc.org/article/S0021925820605981/pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20889975/pdf/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20889975/?tool=EBI
http://intl.jbc.org/cgi/content/abstract/285/50/38978
https://europepmc.org/articles/PMC2998147
https://europepmc.org/articles/PMC2998147?pdf=render
https://api.elsevier.com/content/article/PII:S0021925820605981?httpAccept=text/xml
https://doi.org/10.1074/jbc.m110.181305
https://api.elsevier.com/content/article/PII:S0021925820605981?httpAccept=text/plain
https://syndication.highwire.org/content/doi/10.1074/jbc.M110.181305
P932PMC publication ID2998147
P698PubMed publication ID20889975

P2093author name stringDevanand Kowlessur
Larry S. Tobacman
P2860cites workStructure of the core domain of human cardiac troponin in the Ca(2+)-saturated formQ24306847
Binding of cardiac troponin-I147-163 induces a structural opening in human cardiac troponin-CQ27618840
Mapping subdomains in the C-terminal region of troponin I involved in its binding to troponin C and to thin filamentQ28137766
Identification of a functionally critical protein kinase C phosphorylation residue of cardiac troponin TQ28183029
The highly conserved COOH terminus of troponin I forms a Ca2+-modulated allosteric domain in the troponin complexQ28186310
Phosphorylation or glutamic acid substitution at protein kinase C sites on cardiac troponin I differentially depress myofilament tension and shortening velocityQ28205242
Calcium, thin filaments, and the integrative biology of cardiac contractilityQ28234995
Ca(2+)-regulated structural changes in troponinQ28241337
Mapping of a second actin-tropomyosin and a second troponin C binding site within the C terminus of troponin I, and their importance in the Ca2+-dependent regulation of muscle contractionQ28249121
The C terminus of cardiac troponin I stabilizes the Ca2+-activated state of tropomyosin on actin filamentsQ28268783
Regulation of contraction in striated muscleQ28610114
Primary structure effects on peptide group hydrogen exchangeQ29614750
Probing the non-covalent structure of proteins by amide hydrogen exchange and mass spectrometryQ30426931
A comparison of muscle thin filament models obtained from electron microscopy reconstructions and low-angle X-ray fibre diagrams from non-overlap muscleQ33247663
Ca2+-dependent photocrosslinking of tropomyosin residue 146 to residues 157-163 in the C-terminal domain of troponin I in reconstituted skeletal muscle thin filamentsQ33432398
Troponin regulatory function and dynamics revealed by H/D exchange-mass spectrometryQ33594032
Protein folding intermediates and pathways studied by hydrogen exchangeQ34001354
Structure of the inhibitory region of troponin by site directed spin labeling electron paramagnetic resonanceQ34189676
Three-dimensional structure of calmodulinQ34198142
Mechanism of regulation of phosphate dissociation from actomyosin-ADP-Pi by thin filament proteinsQ34429702
Dynamics of the C-terminal region of TnI in the troponin complex in solution.Q34452418
Thermodynamics of unfolding for turkey ovomucoid third domain: thermal and chemical denaturationQ36277832
Specific myosin heavy chain mutations suppress troponin I defects in Drosophila musclesQ36288309
Negative charges at protein kinase C sites of troponin I stabilize the inactive state of actinQ36303218
Hydrogen exchange identifies native-state motional domains important in protein foldingQ36697047
Structural basis for the regulation of muscle contraction by troponin and tropomyosinQ36791585
Some cardiomyopathy-causing troponin I mutations stabilize a functional intermediate actin state.Q37279326
An atomic model of the thin filament in the relaxed and Ca2+-activated states.Q38444961
Structural aspects of troponin-tropomyosin regulation of skeletal muscle contractionQ39482040
The relationship between biological activity and primary structure of troponin I from white skeletal muscle of the rabbitQ39993829
The C terminus of cardiac troponin I is essential for full inhibitory activity and Ca2+ sensitivity of rat myofibrilsQ41085813
Thin filament-mediated regulation of cardiac contractionQ41117735
Mutations in human cardiac troponin I that are associated with restrictive cardiomyopathy affect basal ATPase activity and the calcium sensitivity of force developmentQ42479969
Cooperativity and switching within the three-state model of muscle regulation.Q42690203
Switching of troponin I: Ca(2+) and myosin-induced activation of heart muscleQ47333776
A universal algorithm for fast and automated charge state deconvolution of electrospray mass-to-charge ratio spectra.Q52227970
Experimental study of the protein folding landscape: unfolding reactions in cytochrome c.Q53929127
Steric-model for activation of muscle thin filaments 1 1 Edited by P.E. WrightQ58052724
The biological importance of each amino acid residue of the troponin I inhibitory sequence 104-115 in the interaction with troponin C and tropomyosin-actinQ68258305
Comparative studies on the inhibitory region of selected species of troponin-I. The use of synthetic peptide analogs to probe structure-function relationshipsQ70976021
Protein conformational stabilities can be determined from hydrogen exchange ratesQ73037283
Photocrosslinking of benzophenone-labeled single cysteine troponin I mutants to other thin filament proteinsQ73454616
A new model of cooperative myosin-thin filament bindingQ73919625
Kinetics and thermodynamics of conformational equilibria in native proteins by hydrogen exchangeQ74178206
C-terminal truncation of cardiac troponin I causes divergent effects on ATPase and force: implications for the pathophysiology of myocardial stunningQ79150632
An interplay between protein disorder and structure confers the Ca2+ regulation of striated muscleQ80020867
Increased Ca2+ affinity of cardiac thin filaments reconstituted with cardiomyopathy-related mutant cardiac troponin IQ82796150
P433issue50
P407language of work or nameEnglishQ1860
P1104number of pages9
P304page(s)38978-38986
P577publication date2010-10-02
P1433published inJournal of Biological ChemistryQ867727
P1476titleLow temperature dynamic mapping reveals unexpected order and disorder in troponin
Low Temperature Dynamic Mapping Reveals Unexpected Order and Disorder in Troponin
P478volume285

Reverse relations

cites work (P2860)
Q36534070Molecular effects of familial hypertrophic cardiomyopathy-related mutations in the TNT1 domain of cTnT.
Q38891067Order-Disorder Transitions in the Cardiac Troponin Complex
Q36984113Role of cardiac troponin I carboxy terminal mobile domain and linker sequence in regulating cardiac contraction
Q36452032Significance of troponin dynamics for Ca2+-mediated regulation of contraction and inherited cardiomyopathy
Q36531702Structures of the troponin core domain containing the cardiomyopathy-causing mutants studied by small-angle X-ray scattering

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