| scholarly article | Q13442814 |
| P2093 | author name string | Larry S Tobacman | |
| Devanand Kowlessur | |||
| P2860 | cites work | Functional consequences of the mutations in human cardiac troponin I gene found in familial hypertrophic cardiomyopathy | Q24291970 |
| Alterations in thin filament regulation induced by a human cardiac troponin T mutant that causes dilated cardiomyopathy are distinct from those induced by troponin T mutants that cause hypertrophic cardiomyopathy | Q24304998 | ||
| Structure of the core domain of human cardiac troponin in the Ca(2+)-saturated form | Q24306847 | ||
| Severe disease expression of cardiac troponin C and T mutations in patients with idiopathic dilated cardiomyopathy | Q24314590 | ||
| Binding of cardiac troponin-I147-163 induces a structural opening in human cardiac troponin-C | Q27618840 | ||
| Phosphorylation-dependent conformational transition of the cardiac specific N-extension of troponin I in cardiac troponin | Q27648119 | ||
| The dilated cardiomyopathy G159D mutation in cardiac troponin C weakens the anchoring interaction with troponin I | Q27652246 | ||
| Structure of the Rigor Actin-Tropomyosin-Myosin Complex | Q27670842 | ||
| Mapping subdomains in the C-terminal region of troponin I involved in its binding to troponin C and to thin filament | Q28137766 | ||
| Role of troponin I phosphorylation in protein kinase C-mediated enhanced contractile performance of rat myocytes | Q28180214 | ||
| Identification of a functionally critical protein kinase C phosphorylation residue of cardiac troponin T | Q28183029 | ||
| The highly conserved COOH terminus of troponin I forms a Ca2+-modulated allosteric domain in the troponin complex | Q28186310 | ||
| Disease-causing mutations in cardiac troponin T: identification of a critical tropomyosin-binding region | Q28199174 | ||
| Phosphorylation or glutamic acid substitution at protein kinase C sites on cardiac troponin I differentially depress myofilament tension and shortening velocity | Q28205242 | ||
| Calcium, thin filaments, and the integrative biology of cardiac contractility | Q28234995 | ||
| Ca(2+)-regulated structural changes in troponin | Q28241337 | ||
| Mutations in the cardiac troponin I gene associated with hypertrophic cardiomyopathy | Q28244969 | ||
| Mapping of a second actin-tropomyosin and a second troponin C binding site within the C terminus of troponin I, and their importance in the Ca2+-dependent regulation of muscle contraction | Q28249121 | ||
| Mutations in Troponin that cause HCM, DCM AND RCM: what can we learn about thin filament function? | Q28264798 | ||
| The C terminus of cardiac troponin I stabilizes the Ca2+-activated state of tropomyosin on actin filaments | Q28268783 | ||
| Cardiac troponin I mutants. Phosphorylation by protein kinases C and A and regulation of Ca(2+)-stimulated MgATPase of reconstituted actomyosin S-1 | Q28291787 | ||
| Thin filament mutations: developing an integrative approach to a complex disorder | Q28307606 | ||
| Regulation of force and unloaded sliding speed in single thin filaments: effects of regulatory proteins and calcium | Q28578662 | ||
| Effects of cardiac thin filament Ca2+: statistical mechanical analysis of a troponin C site II mutant | Q28585773 | ||
| Regulation of contraction in striated muscle | Q28610114 | ||
| Primary structure effects on peptide group hydrogen exchange | Q29614750 | ||
| A model of calcium activation of the cardiac thin filament | Q30503915 | ||
| A comparison of muscle thin filament models obtained from electron microscopy reconstructions and low-angle X-ray fibre diagrams from non-overlap muscle | Q33247663 | ||
| Troponin regulatory function and dynamics revealed by H/D exchange-mass spectrometry | Q33594032 | ||
| Ca(2+)-desensitizing effect of a deletion mutation Delta K210 in cardiac troponin T that causes familial dilated cardiomyopathy. | Q33894656 | ||
| Protein folding intermediates and pathways studied by hydrogen exchange | Q34001354 | ||
| Drosophila muscle regulation characterized by electron microscopy and three-dimensional reconstruction of thin filament mutants. | Q34185014 | ||
| Disease-related cardiac troponins alter thin filament Ca2+ association and dissociation rates. | Q34295777 | ||
| Low Temperature Dynamic Mapping Reveals Unexpected Order and Disorder in Troponin | Q34386049 | ||
| Mechanism of regulation of phosphate dissociation from actomyosin-ADP-Pi by thin filament proteins | Q34429702 | ||
| Dynamics of the C-terminal region of TnI in the troponin complex in solution. | Q34452418 | ||
| Identifying sarcomere gene mutations in hypertrophic cardiomyopathy: a personal history | Q34772983 | ||
| Covalent and noncovalent modification of thin filament action: the essential role of troponin in cardiac muscle regulation. | Q35649608 | ||
| Structural dynamics of C-domain of cardiac troponin I protein in reconstituted thin filament | Q35801924 | ||
| Correlation of molecular and functional effects of mutations in cardiac troponin T linked to familial hypertrophic cardiomyopathy: an integrative in silico/in vitro approach | Q35922629 | ||
| Effects of partial extraction of troponin complex upon the tension-pCa relation in rabbit skeletal muscle. Further evidence that tension development involves cooperative effects within the thin filament | Q36409528 | ||
| Role of the acidic N' region of cardiac troponin I in regulating myocardial function | Q36618121 | ||
| Hydrogen exchange identifies native-state motional domains important in protein folding | Q36697047 | ||
| Structural basis for the regulation of muscle contraction by troponin and tropomyosin | Q36791585 | ||
| Troponin: regulatory function and disorders. | Q37043777 | ||
| An atomic model of the thin filament in the relaxed and Ca2+-activated states. | Q38444961 | ||
| Frequency and clinical expression of cardiac troponin I mutations in 748 consecutive families with hypertrophic cardiomyopathy. | Q38515643 | ||
| Control of muscle contraction | Q40000256 | ||
| How optimal are the binding energetics of barnase and barstar? | Q40295730 | ||
| The C terminus of cardiac troponin I is essential for full inhibitory activity and Ca2+ sensitivity of rat myofibrils | Q41085813 | ||
| Thin filament-mediated regulation of cardiac contraction | Q41117735 | ||
| Site-directed mutation of the trigger calcium-binding sites in cardiac troponin C. | Q41315408 | ||
| Structural basis for Ca2+-regulated muscle relaxation at interaction sites of troponin with actin and tropomyosin | Q41626993 | ||
| Local structure and dynamics in proteins characterized by hydrogen exchange and mass spectrometry | Q41731493 | ||
| Troponin I serines 43/45 and regulation of cardiac myofilament function | Q42524860 | ||
| Cooperativity and switching within the three-state model of muscle regulation. | Q42690203 | ||
| Modulation of contractile activation in skeletal muscle by a calcium-insensitive troponin C mutant | Q45024157 | ||
| Thin filament activation and unloaded shortening velocity of rabbit skinned muscle fibres | Q46907465 | ||
| Troponin, tropomyosin, and actin interactions in the Ca2+ regulation of muscle contraction | Q47846865 | ||
| Functional aberration of myofibrils by cardiomyopathy-causing mutations in the coiled-coil region of the troponin-core domain. | Q51774932 | ||
| Thin-filament regulation of force redevelopment kinetics in rabbit skeletal muscle fibres. | Q51925705 | ||
| Thin filament near-neighbour regulatory unit interactions affect rabbit skeletal muscle steady-state force-Ca(2+) relations. | Q52042668 | ||
| A universal algorithm for fast and automated charge state deconvolution of electrospray mass-to-charge ratio spectra. | Q52227970 | ||
| Comparative NMR studies on cardiac troponin C and a mutant incapable of binding calcium at site II. | Q52481919 | ||
| Investigation of thin filament near-neighbour regulatory unit interactions during force development in skinned cardiac and skeletal muscle. | Q52577226 | ||
| Identification and functional characterization of cardiac troponin I as a novel disease gene in autosomal dominant dilated cardiomyopathy | Q55670729 | ||
| Functional effects of the DCM mutant Gly159Asp Troponin C in skinned muscle fibres | Q57279219 | ||
| Steric-model for activation of muscle thin filaments 1 1 Edited by P.E. Wright | Q58052724 | ||
| Conformation of the Troponin Core Complex in the Thin Filaments of Skeletal Muscle during Relaxation and Active Contraction | Q59289105 | ||
| Protein conformational stabilities can be determined from hydrogen exchange rates | Q73037283 | ||
| Cooperative effect of calcium binding to adjacent troponin molecules on the thin filament-myosin subfragment 1 MgATPase rate | Q73335031 | ||
| Kinetics and thermodynamics of conformational equilibria in native proteins by hydrogen exchange | Q74178206 | ||
| Folding and function of the troponin tail domain. Effects of cardiomyopathic troponin T mutations | Q78454995 | ||
| Identification of a region of troponin I important in signaling cross-bridge-dependent activation of cardiac myofilaments | Q79350688 | ||
| An interplay between protein disorder and structure confers the Ca2+ regulation of striated muscle | Q80020867 | ||
| Modulation of cardiac troponin C function by the cardiac-specific N-terminus of troponin I: influence of PKA phosphorylation and involvement in cardiomyopathies | Q80093425 | ||
| The troponin C G159D mutation blunts myofilament desensitization induced by troponin I Ser23/24 phosphorylation | Q80187075 | ||
| DCM troponin C mutant Gly159Asp blunts the response to troponin phosphorylation | Q80496890 | ||
| P433 | issue | 50 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 42299-42311 | |
| P577 | publication date | 2012-10-12 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Significance of troponin dynamics for Ca2+-mediated regulation of contraction and inherited cardiomyopathy | |
| P478 | volume | 287 |
| Q33677442 | Amide hydrogens reveal a temperature-dependent structural transition that enhances site-II Ca2+-binding affinity in a C-domain mutant of cardiac troponin C |
| Q28066435 | Cardiac Troponin and Tropomyosin: Structural and Cellular Perspectives to Unveil the Hypertrophic Cardiomyopathy Phenotype |
| Q36839397 | Molecular evolution of troponin I and a role of its N-terminal extension in nematode locomotion. |
| Q39621686 | Myofilament Calcium Sensitivity: Consequences of the Effective Concentration of Troponin I. |
| Q53828295 | Role of the C-terminus mobile domain of cardiac troponin I in the regulation of thin filament activation in skinned papillary muscle strips. |
| Q90596238 | Stepwise C-Terminal Truncation of Cardiac Troponin T Alters Function at Low and Saturating Ca2 |
| Q39330777 | Structural Dynamics of the Vimentin Coiled-coil Contact Regions Involved in Filament Assembly as Revealed by Hydrogen-Deuterium Exchange |
| Q36531702 | Structures of the troponin core domain containing the cardiomyopathy-causing mutants studied by small-angle X-ray scattering |
| Q28077921 | The Importance of Intrinsically Disordered Segments of Cardiac Troponin in Modulating Function by Phosphorylation and Disease-Causing Mutations |
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