The properties of the protein tyrosine phosphatase PTPMEG.

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The properties of the protein tyrosine phosphatase PTPMEG. is …
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scholarly articleQ13442814

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P356DOI10.1074/JBC.271.44.27751
P698PubMed publication ID8910369

P2093author name stringGu M
Majerus PW
P2860cites workThe nontransmembrane tyrosine phosphatase PTP-1B localizes to the endoplasmic reticulum via its 35 amino acid C-terminal sequenceQ24301399
Identification, cloning, and expression of a cytosolic megakaryocyte protein-tyrosine-phosphatase with sequence homology to cytoskeletal protein 4.1Q24304972
Isolation of a cDNA clone encoding a human protein-tyrosine phosphatase with homology to the cytoskeletal-associated proteins band 4.1, ezrin, and talinQ24305083
Src kinase associates with a member of a distinct subfamily of protein-tyrosine phosphatases containing an ezrin-like domainQ24305967
Substrate specificity of the protein tyrosine phosphatasesQ24309619
The 64-kDa protein that associates with the platelet-derived growth factor receptor beta subunit via Tyr-1009 is the SH2-containing phosphotyrosine phosphatase SypQ24310396
Cloning and expression of a cytosolic megakaryocyte protein-tyrosine-phosphatase with sequence homology to retinaldehyde-binding protein and yeast SEC14pQ24318402
A major palmitoylated membrane protein of human erythrocytes shows homology to yeast guanylate kinase and to the product of a Drosophila tumor suppressor geneQ24324718
Cloning and characterization of hdlg: the human homologue of the Drosophila discs large tumor suppressor binds to protein 4.1Q24328861
Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactionsQ27729407
Cell transformation and activation of pp60c-src by overexpression of a protein tyrosine phosphataseQ28188457
Molecular cloning of a novel protein-tyrosine phosphatase containing a membrane-binding domain and GLGF repeatsQ28258581
DHR domains in syntrophins, neuronal NO synthases and other intracellular proteinsQ28287673
FAP-1: a protein tyrosine phosphatase that associates with FasQ28287693
Identification of an additional member of the protein-tyrosine-phosphatase family: evidence for alternative splicing in the tyrosine phosphatase domainQ28505143
Amino acid sequences common to rapidly degraded proteins: the PEST hypothesisQ29547538
Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signalingQ29617453
Structural basis for the binding of proline-rich peptides to SH3 domainsQ29620408
Expression of a human T-cell protein-tyrosine-phosphatase in baby hamster kidney cellsQ33804441
Identification of the protein 4.1 binding interface on glycophorin C and p55, a homologue of the Drosophila discs-large tumor suppressor proteinQ34316029
Modulation of cellular signals by calpainQ35238940
Ezrin contains cytoskeleton and membrane binding domains accounting for its proposed role as a membrane-cytoskeletal linkerQ36232246
ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletonsQ36382880
A new function for a phosphotyrosine phosphatase: linking GRB2-Sos to a receptor tyrosine kinaseQ36643931
'Zip codes' direct intracellular protein tyrosine phosphatases to the correct cellular 'address'.Q40664326
Biochemical characterization of a human band 4.1-related protein-tyrosine phosphatase, PTPH1.Q41308546
Activation of a Phosphotyrosine Phosphatase by Tyrosine PhosphorylationQ41566187
cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2.Q44705461
Catalytic domains of the LAR and CD45 protein tyrosine phosphatases from Escherichia coli expression systems: purification and characterization for specificity and mechanismQ45342953
Glycophorin is linked by band 4.1 protein to the human erythrocyte membrane skeletonQ59070174
P433issue44
P407language of work or nameEnglishQ1860
P1104number of pages9
P304page(s)27751-27759
P577publication date1996-11-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleThe properties of the protein tyrosine phosphatase PTPMEG.
P478volume271

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cites work (P2860)
Q78003592Amphiphilic and hydrophilic nature of sheep and human platelet phosphotyrosine phosphatase forms
Q39136968Calpain-dependent cleavage of SHP-1 and SHP-2 is involved in the dephosphorylation of Jurkat T cells induced by Entamoeba histolytica
Q36783478Calpain-mediated regulation of platelet signaling pathways
Q24550152Dephosphorylation of beta2-syntrophin and Ca2+/mu-calpain-mediated cleavage of ICA512 upon stimulation of insulin secretion
Q29619893ERM proteins and merlin: integrators at the cell cortex
Q33859413Effects of overexpression of PTP36, a putative protein tyrosine phosphatase, on cell adhesion, cell growth, and cytoskeletons in HeLa cells
Q42816004Evidence for a calpeptin-sensitive protein-tyrosine phosphatase upstream of the small GTPase Rho. A novel role for the calpain inhibitor calpeptin in the inhibition of protein-tyrosine phosphatases
Q36342597Evidence that beta3 integrin-induced Rac activation involves the calpain-dependent formation of integrin clusters that are distinct from the focal complexes and focal adhesions that form as Rac and RhoA become active
Q24290224Generation of novel cytoplasmic forms of protein tyrosine phosphatase epsilon by proteolytic processing and translational control
Q41975625Microvesicle release is associated with extensive protein tyrosine dephosphorylation in platelets stimulated by A23187 or a mixture of thrombin and collagen
Q38767239Molecular Basis of the Interaction of the Human Protein Tyrosine Phosphatase Non-receptor Type 4 (PTPN4) with the Mitogen-activated Protein Kinase p38γ.
Q22253995Molecular cloning of a novel NF2/ERM/4.1 superfamily gene, ehm2, that is expressed in high-metastatic K1735 murine melanoma cells
Q28509897Nischarin, a novel protein that interacts with the integrin alpha5 subunit and inhibits cell migration
Q30009863PTPN4 negatively regulates CrkI in human cell lines
Q37611336Physiological signaling specificity by protein tyrosine phosphatases
Q37094065Protein tyrosine phosphatases: regulatory mechanisms
Q48347371Proteolytic processing of the receptor-type protein tyrosine phosphatase PTPBR7.
Q33867588Regulation of phosphorylation level and distribution of PTP36, a putative protein tyrosine phosphatase, by cell-substrate adhesion
Q43655712Regulation of protein-tyrosine phosphatases alpha and epsilon by calpain-mediated proteolytic cleavage
Q41367437Regulation of the Human Phosphatase PTPN4 by the inter-domain linker connecting the PDZ and the phosphatase domains.
Q24302524Regulation of the catalytic activity of the human phosphatase PTPN4 by its PDZ domain
Q36749161Role of mu-calpain in proteolytic cleavage of brain L-glutamic acid decarboxylase
Q24647975The effect of overexpression of the protein tyrosine phosphatase PTPMEG on cell growth and on colony formation in soft agar in COS-7 cells
Q28507911The protein tyrosine phosphatase PTPN4/PTP-MEG1, an enzyme capable of dephosphorylating the TCR ITAMs and regulating NF-kappaB, is dispensable for T cell development and/or T cell effector functions
Q33289430The protein-tyrosine phosphatase PTPMEG interacts with glutamate receptor delta 2 and epsilon subunits.
Q36673335The δ2 glutamate receptor gates long-term depression by coordinating interactions between two AMPA receptor phosphorylation sites
Q65002616miR-181c-5p Exacerbates Hypoxia/Reoxygenation-Induced Cardiomyocyte Apoptosis via Targeting PTPN4.

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